Antitumor activity of Portulaca oleracea L. polysaccharides against cervical carcinoma in vitro and in vivo

Carbohydrate Polymers

Volumn 96, Issue 2, 2013, Pages 376-383

  Zhao, Rui ^a,b   Gao, Xu ^b   Cai, Yaping ^a   Shao, Xingyue ^c   Jia, Guiyan ^a   Huang, Yulan ^a   Qin, Xuegong ^a   Wang, Jingwei ^a   Zheng, Xiaoliang ^a  

^a HEILONGJIANG AUGUST FIRST LAND RECLAMATION UNIVERSITY   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

^c DAQING OILFIELD CO LTD   (China)

Author keywords

Apoptosis; Cell cycle; Cervical carcinoma; Polysaccharides; Portulaca oleracea L.

Indexed keywords

CELL DEATH; CELL PROLIFERATION; COLUMN CHROMATOGRAPHY; DISEASES; DRUG PRODUCTS; ION EXCHANGE; POLYSACCHARIDES;

ANTI-TUMOR ACTIVITIES; ASSOCIATED MECHANISM; CELL CYCLE; CELL-CYCLE ARREST; CERVICAL CANCER CELLS; CERVICAL CARCINOMA; PORTULACA OLERACEA; WATER-SOLUBLE POLYSACCHARIDES;

CYTOLOGY;

GALIUM; GALIUM VERUM; MUS; PORTULACA OLERACEA;

EID: 84877856457     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2013.04.023     Document Type: Article

References (18)

1. Ashokkumar, P., & Sudhandiran, G. (2011). Luteolin inhibits cell proliferation during Azoxymethane-induced experimental colon carcinogenesis via Wnt/β-catenin pathway. Investigational New Drugs, 29, 273-284.
2. Boatright, K.M., & Salvesen, G. S. (2003). Mechanisms of caspase activation. Current Opinion in Cell Biology, 15, 725-731. (Pubitemid 37492933)
3. Chang, S.C., Hsu, B. Y., & Chen, B. H. (2010). Structural characterization of polysaccharides from Zizyphus jujuba and evaluation of antioxidant activity. International Journal of Biological Macromolecules, 47, 445-453.
4. Chen, T., Zhu, L., Liu, X. Y., Li, Y. Y., Zhao, C. D., Xu, Z. G., et al. (2011). Synthesis and antioxidant activity of phosphorylated polysaccharide from Portulaca oleracea L. with H3PW12O40 immobilized on polyamine functionalized polystyrene bead as catalyst. Journal of Molecular Catalysis A: Chemical, 342, 74-82.
5. Cui, F., Tao, W., Xu, Z., Guo, W., Xu, H., Ao, Z., et al. (2007). Structural analysis of antitumor heteropolysaccharide GFPS1b from the cultured mycelia of Grifola frondosa GF9801. Bioresource Technology, 98, 395-401. (Pubitemid 44332166)
6. Hartwell, L., & Weinert, T. (1989). Checkpoints: Controls that ensure the order of cell cycle events. Science, 246, 629-634. (Pubitemid 19283354)
7. Hu, Y.W., Liu, C. Y., Du, C. M., Zhang, J., Wu, W. Q., & Gu, Z. L. (2009). Induction of apoptosis in human hepatocarcinoma SMMC-7721 cells in vitro by flavonoids from Astragalus complanatus. Journal of Ethnopharmacology, 123, 293-301.
8. Hung, C.F., Hsu, B. Y., Chang, S. C., & Chen, B. H. (2012). Antiproliferation of melanoma cells by polysaccharide isolated from Zizyphus jujuba. Nutrition, 28, 98-105.
9. Li, J., Li, Q. W., Peng, Y., Zhao, R., Han, Z. S., & Gao, D. W. (2010). Protective effects of fraction 1a of polysaccharides isolated from Solanum nigrum Linne on thymus in tumor-bearing mice. Journal of Ethnopharmacology, 129, 350-356.
10. Kessel, D., & Luo, Y. (2000). Cells in cryptophycin-induced cell-cycle arrest are susceptible to apoptosis. Cancer Letters, 151, 25-29. (Pubitemid 30155581)
11. Lavrik, I.N., Golks, A., & Krammer, P. H. (2005). Caspases: Pharmacological manipulation of cell death. Journal of Clinical Investigation, 115, 2665-2672. (Pubitemid 41434390)
12. Peter, M.E., & Krammer, P. H. (2003). The CD95(APO-1/Fas) DISC and beyond. Cell Death and Differentiation, 10, 26-35. (Pubitemid 36511830)
13. Schwartsmann, G., Ratain, M. J., Cragg, G. M., Wong, J. E., Saijo, N., & Parkinson, D. R. (2002). Anticancer drug discovery and development throughout the world. Journal of Clinical Oncology, 20, 47S-59S.
14. Tao, Y.Z., Zhang, Y. Y., & Zhang, L. N. (2009). Chemical modification and antitumor activities of two polysaccharide-protein complexes from Pleurotus tuberregium. International Journal of Biological Macromolecules, 45, 109-115.
15. Wu, H., Guo, H. W., & Zhao, R. (2006). Effect of lycium barbarum polysaccharide on the improvement of antioxidant ability and DNA Damage in NIDDM rats. Yakugaku Zasshi. Journal of the Pharmaceutical Society of Japan, 126, 365-371.
16. Xiang, L., Xing, D., Wang, W., Wang, R., Ding, Y., & Du, L. (2005). Alkaloids from Portulaca oleracea L. Phytochemistry, 66, 2595-2601.
17. Zhang, M., Chen, H., Huang, J., Zhong, L., Zhu, C. P., & Zhang, S. H. (2005). Effect of Lycium barbarum polysaccharide on human hepatoma QGY7703 cells: Inhibition of proliferation and induction of apoptosis. Life Sciences, 76, 2115-2124. (Pubitemid 40249369)
18. Zhao, L.Y., Dong, Y. H., Chen, G. T., & Hu, Q. H. (2010). Extraction, purification, characterization and antitumor activity of polysaccharides from Ganoderma lucidum. Carbohydrate Polymers, 80, 783-789.