Toll-Like Receptor 4 Mediates Acute Lung Injury Induced by High Mobility Group Box-1

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Deng, Yuxiao ^a   Yang, Zhongwei ^a   Gao, Yuan ^a   Xu, Huan ^a   Zheng, Beijie ^a   Jiang, Min ^b   Xu, Jin ^a   He, Zhengyu ^a   Wang, Xiangrui ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Stt Key Lab of Med Neurobiology   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 1BETA; LENTIVIRUS VECTOR; MESSENGER RNA; NEUTRALIZING ANTIBODY; SHORT HAIRPIN RNA; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; PRIMER DNA; RECOMBINANT PROTEIN; TLR4 PROTEIN, RAT;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; GENE EXPRESSION; LUNG ALVEOLUS MACROPHAGE; MALE; NONHUMAN; PNEUMONIA; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UPREGULATION; ANALYSIS OF VARIANCE; ANIMAL; CHEMICALLY INDUCED; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; HISTOLOGY; HUMAN; IMMUNOLOGY; MACROPHAGE; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SPRAGUE DAWLEY RAT; TOXICITY; WESTERN BLOTTING;

ACUTE LUNG INJURY; ANALYSIS OF VARIANCE; ANIMALS; ANTIBODIES, NEUTRALIZING; BLOTTING, WESTERN; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HISTOLOGICAL TECHNIQUES; HMGB1 PROTEIN; HUMANS; INTERLEUKIN-1BETA; MACROPHAGES; MALE; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RECOMBINANT PROTEINS; RNA INTERFERENCE; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84877850224     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0064375     Document Type: Article

References (39)

1. Ware LB, Matthay MA, (2000) The acute respiratory distress syndrome. N Engl J Med 342: 1334-1349.
2. Hall RI, Smith MS, Rocker G, (1997) The systemic inflammatory response to cardiopulmonary bypass: pathophysiological, therapeutic, and pharmacological considerations. Anesth Analg 85: 766-782.
3. Miller BE, Levy JH, (1997) The inflammatory response to cardiopulmonary bypass. J Cardiothorac Vasc Anesth 11: 355-366.
4. He Z, Gao Y, Deng Y, Li W, Chen Y, et al. (2012) Lipopolysaccharide induces lung fibroblast proliferation through Toll-like receptor 4 signaling and the phosphoinositide3-kinase-Akt pathway. PLoS One 7: e35926.
5. He Z, Zhu Y, Jiang H, (2009) Inhibiting toll-like receptor 4 signaling ameliorates pulmonary fibrosis during acute lung injury induced by lipopolysaccharide: an experimental study. Respir Res 10: 126.
6. Tian J, Wang Y, He Z, Gao Y, Rundhaug JE, et al. (2011) Hydroxyethyl starch (130 kD) inhibits Toll-like receptor 4 signaling pathways in rat lungs challenged with lipopolysaccharide. Anesth Analg 113: 112-119.
7. Hu G, Malik AB, Minshall RD, (2010) Toll-like receptor 4 mediates neutrophil sequestration and lung injury induced by endotoxin and hyperinflation. Crit Care Med 38: 194-201.
8. Lv T, Shen X, Shi Y, Song Y, (2009) TLR4 is essential in acute lung injury induced by unresuscitated hemorrhagic shock. J Trauma 66: 124-131.
9. Gribar SC, Richardson WM, Sodhi CP, Hackam DJ, (2008) No longer an innocent bystander: epithelial toll-like receptor signaling in the development of mucosal inflammation. Mol Med 14: 645-659.
10. Perros F, Lambrecht BN, Hammad H, (2011) TLR4 signalling in pulmonary stromal cells is critical for inflammation and immunity in the airways. Respir Res 12: 125.
11. Bianchi ME, (2007) DAMPs, PAMPs and alarmins: all we need to know about danger. J Leukoc Biol 81: 1-5.
12. Kawai T, Akira S, (2010) The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 11: 373-384.
13. Li J, Wang H, Mason JM, Levine J, Yu M, et al. (2004) Recombinant HMGB1 with cytokine-stimulating activity. J Immunol Methods 289: 211-223.
14. Lotze MT, Tracey KJ, (2005) High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat Rev Immunol 5: 331-342.
15. Andersson U, Erlandsson-Harris H, Yang H, Tracey KJ, (2002) HMGB1 as a DNA-binding cytokine. J Leukoc Biol 72: 1084-1091.
16. Dumitriu IE, Baruah P, Manfredi AA, Bianchi ME, Rovere-Querini P, (2005) HMGB1: guiding immunity from within. Trends Immunol 26: 381-387.
17. Yang H, Wang H, Czura CJ, Tracey KJ, (2005) The cytokine activity of HMGB1. J Leukoc Biol 78: 1-8.
18. Kokkola R, Sundberg E, Ulfgren AK, Palmblad K, Li J, et al. (2002) High mobility group box chromosomal protein 1: a novel proinflammatory mediator in synovitis. Arthritis Rheum 46: 2598-2603.
19. Andersson U, Wang H, Palmblad K, Aveberger AC, Bloom O, et al. (2000) High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes. J Exp Med 192: 565-570.
20. Degryse B, Bonaldi T, Scaffidi P, Muller S, Resnati M, et al. (2001) The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells. J Cell Biol 152: 1197-1206.
21. Fiuza C, Bustin M, Talwar S, Tropea M, Gerstenberger E, et al. (2003) Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells. Blood 101: 2652-2660.
22. Fink MP, (2007) Bench-to-bedside review: High-mobility group box 1 and critical illness. Crit Care 11: 229.
23. Hatada T, Wada H, Nobori T, Okabayashi K, Maruyama K, et al. (2005) Plasma concentrations and importance of High Mobility Group Box protein in the prognosis of organ failure in patients with disseminated intravascular coagulation. Thromb Haemost 94: 975-979.
24. Ueno H, Matsuda T, Hashimoto S, Amaya F, Kitamura Y, et al. (2004) Contributions of high mobility group box protein in experimental and clinical acute lung injury. Am J Respir Crit Care Med 170: 1310-1316.
25. Kim JY, Park JS, Strassheim D, Douglas I, Diaz del Valle F, et al. (2005) HMGB1 contributes to the development of acute lung injury after hemorrhage. Am J Physiol Lung Cell Mol Physiol 288: L958-965.
26. Abraham E, Arcaroli J, Carmody A, Wang HC, Tracey KJ, (2000) Cutting edge: HMG-1 as a mediator of acute lung inflammation. Journal of Immunology 165: 2950-2954.
27. Ulich TR, Yi ES, Yin S, Smith C, Remick D, (1994) Intratracheal administration of endotoxin and cytokines. VII. The soluble interleukin-1 receptor and the soluble tumor necrosis factor receptor II (p80) inhibit acute inflammation. Clin Immunol Immunopathol 72: 137-140.
28. Park WY, Goodman RB, Steinberg KP, Ruzinski JT, Radella F, 2nd, et al (2001) Cytokine balance in the lungs of patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 164: 1896-1903.
29. Luo Y, Zhang B, Xu DQ, Liu Y, Dong MQ, et al. (2011) Protective effect of bicyclol on lipopolysaccharide-induced acute lung injury in mice. Pulm Pharmacol Ther 24: 240-246.
30. Akira S, (2003) Mammalian Toll-like receptors. Curr Opin Immunol 15: 5-11.
31. Medzhitov R, Janeway C Jr, (2000) Innate immunity. N Engl J Med 343: 338-344.
32. Baudouin S, (2010) Innate immune defense on the attack in acute lung injury. Crit Care Med 38: 328-329.
33. Kaczorowski DJ, Mollen KP, Edmonds R, Billiar TR, (2008) Early events in the recognition of danger signals after tissue injury. J Leukoc Biol 83: 546-552.
34. Abraham E, Arcaroli J, Carmody A, Wang H, Tracey KJ, (2000) HMG-1 as a mediator of acute lung inflammation. J Immunol 165: 2950-2954.
35. Voll RE, Urbonaviciute V, Herrmann M, Kalden JR, (2008) High mobility group box 1 in the pathogenesis of inflammatory and autoimmune diseases. Isr Med Assoc J 10: 26-28.
36. Hori O, Brett J, Slattery T, Cao R, Zhang J, et al. (1995) The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system. J Biol Chem 270: 25752-25761.
37. Huttunen HJ, Rauvala H, (2004) Amphoterin as an extracellular regulator of cell motility: from discovery to disease. J Intern Med 255: 351-366.
38. Park JS, Gamboni-Robertson F, He Q, Svetkauskaite D, Kim JY, et al. (2006) High mobility group box 1 protein interacts with multiple Toll-like receptors. Am J Physiol Cell Physiol 290: C917-924.
39. Park JS, Svetkauskaite D, He Q, Kim JY, Strassheim D, et al. (2004) Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J Biol Chem 279: 7370-7377.