-
1
-
-
0038387390
-
The dawning era of polymer therapeutics
-
Duncan R. The dawning era of polymer therapeutics. Nat Rev Drug Discov. 2003;2(5): 347-60.
-
(2003)
Nat Rev Drug Discov
, vol.2
, Issue.5
, pp. 347-360
-
-
Duncan, R.1
-
2
-
-
32244443852
-
Polymer architecture and drug delivery
-
Qiu LY, Bae YH. Polymer architecture and drug delivery. Pharm Res. 2006;23(1): 1-30.
-
(2006)
Pharm Res
, vol.23
, Issue.1
, pp. 1-30
-
-
Qiu, L.Y.1
Bae, Y.H.2
-
3
-
-
0035342007
-
Poly (amidoamine)(PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications
-
Esfand R, Tomalia DA. Poly (amidoamine)(PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications. Drug Discov Today. 2001;6(8): 427-36.
-
(2001)
Drug Discov Today
, vol.6
, Issue.8
, pp. 427-436
-
-
Esfand, R.1
Tomalia, D.A.2
-
4
-
-
0021586266
-
A new class of polymers: starburst-dendritic macromolecules
-
Tomalia DA, Baker H, Dewald J, Hall M, Kallos G, Martin S, et al. A new class of polymers: starburst-dendritic macromolecules. Polym J. 1985;17(1): 117-32.
-
(1985)
Polym J
, vol.17
, Issue.1
, pp. 117-132
-
-
Tomalia, D.A.1
Baker, H.2
Dewald, J.3
Hall, M.4
Kallos, G.5
Martin, S.6
-
5
-
-
33847017288
-
Dendrimers as multi-purpose nanodevices for oncology drug delivery and diagnostic imaging
-
Tomalia D, Reyna L, Svenson S. Dendrimers as multi-purpose nanodevices for oncology drug delivery and diagnostic imaging. Biochem Soc Trans. 2007;35: 61-7.
-
(2007)
Biochem Soc Trans
, vol.35
, pp. 61-67
-
-
Tomalia, D.1
Reyna, L.2
Svenson, S.3
-
6
-
-
28744445460
-
Dendrimer biocompatibility and toxicity
-
Duncan R, Izzo L. Dendrimer biocompatibility and toxicity. Adv Drug Deliv Rev. 2005;57(15): 2215-37.
-
(2005)
Adv Drug Deliv Rev
, vol.57
, Issue.15
, pp. 2215-2237
-
-
Duncan, R.1
Izzo, L.2
-
7
-
-
0034005436
-
Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo
-
Malik N, Wiwattanapatapee R, Klopsch R, Lorenz K, Frey H, Weener JW, et al. Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo. J Control Release. 2000;65(1-2): 133-48.
-
(2000)
J Control Release
, vol.65
, Issue.1-2
, pp. 133-148
-
-
Malik, N.1
Wiwattanapatapee, R.2
Klopsch, R.3
Lorenz, K.4
Frey, H.5
Weener, J.W.6
-
8
-
-
79959874185
-
Designing dendrimers for drug delivery and imaging: pharmacokinetic considerations
-
Wijagkanalan W, Kawakami S, Hashida M. Designing dendrimers for drug delivery and imaging: pharmacokinetic considerations. Pharm Res. 2011;28(7): 1500-19.
-
(2011)
Pharm Res
, vol.28
, Issue.7
, pp. 1500-1519
-
-
Wijagkanalan, W.1
Kawakami, S.2
Hashida, M.3
-
9
-
-
70349987594
-
Development of HPMA copolymer-anticancer conjugates: clinical experience and lessons learnt
-
Duncan R. Development of HPMA copolymer-anticancer conjugates: clinical experience and lessons learnt. Adv Drug Deliv Rev. 2009;61(13): 1131-48.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, Issue.13
, pp. 1131-1148
-
-
Duncan, R.1
-
10
-
-
75749149269
-
HPMA copolymers: origins, early developments, present, and future
-
Kopecek J, Kopecková P. HPMA copolymers: origins, early developments, present, and future. Adv Drug Deliv Rev. 2010;62(2): 122-49.
-
(2010)
Adv Drug Deliv Rev
, vol.62
, Issue.2
, pp. 122-149
-
-
Kopecek, J.1
Kopecková, P.2
-
11
-
-
56949085259
-
Tumor-targeted HPMA copolymer-(RGDfK)-(CHX-A″-DTPA) conjugates show increased kidney accumulation
-
Borgman M, Coleman T, Kolhatkar R, Geyser-Stoops S, Line B, Ghandehari H. Tumor-targeted HPMA copolymer-(RGDfK)-(CHX-A″-DTPA) conjugates show increased kidney accumulation. J Control Release. 2008;132(3): 193-9.
-
(2008)
J Control Release
, vol.132
, Issue.3
, pp. 193-199
-
-
Borgman, M.1
Coleman, T.2
Kolhatkar, R.3
Geyser-Stoops, S.4
Line, B.5
Ghandehari, H.6
-
12
-
-
0027701071
-
Effect of side-chains on solution properties of N-(2-hydroxypropyl) methacrylamide copolymers in aqueous solvents
-
Konak C, Rathi RC, Kopeckova P, Kopecek J. Effect of side-chains on solution properties of N-(2-hydroxypropyl) methacrylamide copolymers in aqueous solvents. Polymer. 1993;34(22): 4767-73.
-
(1993)
Polymer
, vol.34
, Issue.22
, pp. 4767-4773
-
-
Konak, C.1
Rathi, R.C.2
Kopeckova, P.3
Kopecek, J.4
-
13
-
-
28244435462
-
Effect of physicochemical modification on the biodistribution and tumor accumulation of HPMA copolymers
-
Lammers T, Kuhnlein R, Kissel M, Subr V, Etrych T, Pola R, et al. Effect of physicochemical modification on the biodistribution and tumor accumulation of HPMA copolymers. J Control Release. 2005;110(1): 103-18.
-
(2005)
J Control Release
, vol.110
, Issue.1
, pp. 103-118
-
-
Lammers, T.1
Kuhnlein, R.2
Kissel, M.3
Subr, V.4
Etrych, T.5
Pola, R.6
-
14
-
-
70449732850
-
The influence of polymer topology on pharmacokinetics: differences between cyclic and linear PEGylated poly (acrylic acid) comb polymers
-
Chen B, Jerger K, Fréchet JMJ, Szoka Jr FC. The influence of polymer topology on pharmacokinetics: differences between cyclic and linear PEGylated poly (acrylic acid) comb polymers. J Control Release. 2009;140(3): 203-9.
-
(2009)
J Control Release
, vol.140
, Issue.3
, pp. 203-209
-
-
Chen, B.1
Jerger, K.2
Fréchet, J.M.J.3
Szoka Jr., F.C.4
-
15
-
-
68949166354
-
Soluble polymer carriers for the treatment of cancer: the importance of molecular architecture
-
Fox ME, Szoka FC, Fre chet JMJ. Soluble polymer carriers for the treatment of cancer: the importance of molecular architecture. Acc Chem Res. 2009;42(8): 1141-51.
-
(2009)
Acc Chem Res
, vol.42
, Issue.8
, pp. 1141-1151
-
-
Fox, M.E.1
Szoka, F.C.2
Fre Chet, J.M.J.3
-
16
-
-
67849104970
-
Dependence of pharmacokinetics and biodistribution on polymer architecture: effect of cyclic versus linear polymers
-
Nasongkla N, Chen B, Macaraeg N, Fox ME, Fréchet JMJ, Szoka FC. Dependence of pharmacokinetics and biodistribution on polymer architecture: effect of cyclic versus linear polymers. J Am Chem Soc. 2009;131(11): 3842-3.
-
(2009)
J Am Chem Soc
, vol.131
, Issue.11
, pp. 3842-3843
-
-
Nasongkla, N.1
Chen, B.2
Macaraeg, N.3
Fox, M.E.4
Fréchet, J.M.J.5
Szoka, F.C.6
-
17
-
-
78651334140
-
Comparative biodistribution of PAMAM dendrimers and HPMA copolymers in ovarian-tumor-bearing mice
-
Sadekar S, Ray A, Janat-Amsbury M, Peterson C, Ghandehari H. Comparative biodistribution of PAMAM dendrimers and HPMA copolymers in ovarian-tumor-bearing mice. Biomacromolecules. 2011;12(1): 88-96.
-
(2011)
Biomacromolecules
, vol.12
, Issue.1
, pp. 88-96
-
-
Sadekar, S.1
Ray, A.2
Janat-Amsbury, M.3
Peterson, C.4
Ghandehari, H.5
-
19
-
-
33646150223
-
Effects of glomerular filtration rate on Ficoll sieving coefficients (theta) in rats
-
Rippe C, Asgeirsson D, Venturoli D, Rippe A, Rippe B. Effects of glomerular filtration rate on Ficoll sieving coefficients (theta) in rats. Kidney Int. 2006;69(8): 1326-32.
-
(2006)
Kidney Int
, vol.69
, Issue.8
, pp. 1326-1332
-
-
Rippe, C.1
Asgeirsson, D.2
Venturoli, D.3
Rippe, A.4
Rippe, B.5
-
20
-
-
0035923461
-
Viscosimetric, hydrodynamic, and conformational properties of dendrimers and dendrons
-
Tande B, Wagner N, Mackay M, Hawker C, Jeong M. Viscosimetric, hydrodynamic, and conformational properties of dendrimers and dendrons. Macromolecules. 2001;34(24): 8580-5.
-
(2001)
Macromolecules
, vol.34
, Issue.24
, pp. 8580-8585
-
-
Tande, B.1
Wagner, N.2
Mackay, M.3
Hawker, C.4
Jeong, M.5
-
21
-
-
75749144204
-
Structural and chemical aspects of HPMA copolymers as drug carriers
-
Ulbrich K, Subr V. Structural and chemical aspects of HPMA copolymers as drug carriers. Adv Drug Deliv Rev. 2010;62(2): 150-66.
-
(2010)
Adv Drug Deliv Rev
, vol.62
, Issue.2
, pp. 150-166
-
-
Ulbrich, K.1
Subr, V.2
-
22
-
-
70350234894
-
A modeling analysis of the effects of molecular size and binding affinity on tumor targeting
-
Schmidt MM, Wittrup KD. A modeling analysis of the effects of molecular size and binding affinity on tumor targeting. Mol Cancer Ther. 2009;8(10): 2861-71.
-
(2009)
Mol Cancer Ther
, vol.8
, Issue.10
, pp. 2861-2871
-
-
Schmidt, M.M.1
Wittrup, K.D.2
-
23
-
-
0019632722
-
Effects of molecular size and configuration on diffusion in microporous membranes
-
Deen W, Bohrer M, Epstein N. Effects of molecular size and configuration on diffusion in microporous membranes. AICHE J. 1981;27(6): 952-9.
-
(1981)
AICHE J
, vol.27
, Issue.6
, pp. 952-959
-
-
Deen, W.1
Bohrer, M.2
Epstein, N.3
-
24
-
-
0030590447
-
Pharmacokinetic evaluation of polymeric carriers
-
Nishikawa M, Takakura Y, Hashida M. Pharmacokinetic evaluation of polymeric carriers. Adv Drug Deliv Rev. 1996;21(2): 135-55.
-
(1996)
Adv Drug Deliv Rev
, vol.21
, Issue.2
, pp. 135-155
-
-
Nishikawa, M.1
Takakura, Y.2
Hashida, M.3
-
25
-
-
0034000453
-
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review
-
Maeda H, Wu J, Sawa T, Matsumura Y, Hori K. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J Control Release. 2000;65(1-2): 271-84.
-
(2000)
J Control Release
, vol.65
, Issue.1-2
, pp. 271-284
-
-
Maeda, H.1
Wu, J.2
Sawa, T.3
Matsumura, Y.4
Hori, K.5
-
26
-
-
79959393938
-
Delivery of molecular and nanoscale medicine to tumors: transport barriers and strategies
-
Chauhan VP, Stylianopoulos T, Boucher Y, Jain RK. Delivery of molecular and nanoscale medicine to tumors: transport barriers and strategies. Annu Rev Chem Biomol. 2011;2: 281-98.
-
(2011)
Annu Rev Chem Biomol
, vol.2
, pp. 281-298
-
-
Chauhan, V.P.1
Stylianopoulos, T.2
Boucher, Y.3
Jain, R.K.4
-
27
-
-
18844370132
-
Biological evaluation of polyester dendrimer: poly (ethylene oxide)"bow-tie" hybrids with tunable molecular weight and architecture
-
Gillies ER, Dy E, Fréchet JMJ, Szoka FC. Biological evaluation of polyester dendrimer: poly (ethylene oxide)"bow-tie" hybrids with tunable molecular weight and architecture. Mol Pharm. 2005;2(2): 129-38.
-
(2005)
Mol Pharm
, vol.2
, Issue.2
, pp. 129-138
-
-
Gillies, E.R.1
Dy, E.2
Fréchet, J.M.J.3
Szoka, F.C.4
-
28
-
-
51049092122
-
The role of the size and number of polyethylene glycol chains in the biodistribution and tumor localization of triazine dendrimers
-
Lim J, Guo Y, Rostollan CL, Stanfield J, Hsieh JT, Sun X, et al. The role of the size and number of polyethylene glycol chains in the biodistribution and tumor localization of triazine dendrimers. Mol Pharm. 2008;5(4): 540-7.
-
(2008)
Mol Pharm
, vol.5
, Issue.4
, pp. 540-547
-
-
Lim, J.1
Guo, Y.2
Rostollan, C.L.3
Stanfield, J.4
Hsieh, J.T.5
Sun, X.6
-
29
-
-
0023219734
-
Transport of molecules in the tumor interstitium: a review
-
Jain RK. Transport of molecules in the tumor interstitium: a review. Cancer Res. 1987;47(12): 3039.
-
(1987)
Cancer Res
, vol.47
, Issue.12
, pp. 3039
-
-
Jain, R.K.1
-
30
-
-
0034809350
-
Effects of filtration rate on the glomerular barrier and clearance of four differently shaped molecules
-
Ohlson M, Sörensson J, Lindström K, Blom AM, Fries E, Haraldsson B. Effects of filtration rate on the glomerular barrier and clearance of four differently shaped molecules. Am J Physiol-Renal. 2001;281(1): F103.
-
(2001)
Am J Physiol-Renal
, vol.281
, Issue.1
-
-
Ohlson, M.1
Sörensson, J.2
Lindström, K.3
Blom, A.M.4
Fries, E.5
Haraldsson, B.6
-
31
-
-
15044362503
-
Ficoll and dextran vs. globular proteins as probes for testing glomerular permselectivity: effects of molecular size, shape, charge, and deformability
-
Venturoli D, Rippe B. Ficoll and dextran vs. globular proteins as probes for testing glomerular permselectivity: effects of molecular size, shape, charge, and deformability. Am J Physiol-Renal. 2005;288(4): F605.
-
(2005)
Am J Physiol-Renal
, vol.288
, Issue.4
-
-
Venturoli, D.1
Rippe, B.2
-
32
-
-
0032978690
-
Diffusion of macromolecules in agarose gels: comparison of linear and globular configurations
-
Pluen A, Netti PA, Jain RK, Berk DA. Diffusion of macromolecules in agarose gels: comparison of linear and globular configurations. Biophys J. 1999;77(1): 542-52.
-
(1999)
Biophys J
, vol.77
, Issue.1
, pp. 542-552
-
-
Pluen, A.1
Netti, P.A.2
Jain, R.K.3
Berk, D.A.4
-
33
-
-
35148860246
-
Reptation of a polymer chain in the presence of fixed obstacles
-
Gennes PG. Reptation of a polymer chain in the presence of fixed obstacles. J Chem Phys. 1971;55(2): 572-9.
-
(1971)
J Chem Phys
, vol.55
, Issue.2
, pp. 572-579
-
-
Gennes, P.G.1
-
34
-
-
0018670579
-
Macromolecule transport across glomerular capillaries: application of pore theory
-
Deen WM, Bohrer MP, Brenner BM. Macromolecule transport across glomerular capillaries: application of pore theory. Kidney Int. 1979;16(3): 353-65.
-
(1979)
Kidney Int
, vol.16
, Issue.3
, pp. 353-365
-
-
Deen, W.M.1
Bohrer, M.P.2
Brenner, B.M.3
-
35
-
-
0036103603
-
Renal tubular damage detected by dynamic micro-MRI with a dendrimer-based magnetic resonance contrast agent
-
Kobayashi H, Kawamoto S, Jo SK, Sato N, Saga T, Hiraga A, et al. Renal tubular damage detected by dynamic micro-MRI with a dendrimer-based magnetic resonance contrast agent. Kidney Int. 2002;61(6): 1980-5.
-
(2002)
Kidney Int
, vol.61
, Issue.6
, pp. 1980-1985
-
-
Kobayashi, H.1
Kawamoto, S.2
Jo, S.K.3
Sato, N.4
Saga, T.5
Hiraga, A.6
-
36
-
-
33644772618
-
Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers
-
Dreher MR, Liu W, Michelich CR, Dewhirst MW, Yuan F, Chilkoti A. Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers. J Natl Cancer Inst. 2006;98(5): 335-44.
-
(2006)
J Natl Cancer Inst
, vol.98
, Issue.5
, pp. 335-344
-
-
Dreher, M.R.1
Liu, W.2
Michelich, C.R.3
Dewhirst, M.W.4
Yuan, F.5
Chilkoti, A.6
-
37
-
-
1342323477
-
The role of molecular conformation on tumor uptake of polymeric contrast agents
-
Uzgiris E. The role of molecular conformation on tumor uptake of polymeric contrast agents. Invest Radiol. 2004;39(3): 131-7.
-
(2004)
Invest Radiol
, vol.39
, Issue.3
, pp. 131-137
-
-
Uzgiris, E.1
-
38
-
-
0842344665
-
Conformation and structure of polymeric contrast agents for medical imaging
-
Uzgiris E, Cline H, Moasser B, Grimmond B, Amaratunga M, Smith JF, et al. Conformation and structure of polymeric contrast agents for medical imaging. Biomacromolecules. 2004;5(1): 54-61.
-
(2004)
Biomacromolecules
, vol.5
, Issue.1
, pp. 54-61
-
-
Uzgiris, E.1
Cline, H.2
Moasser, B.3
Grimmond, B.4
Amaratunga, M.5
Smith, J.F.6
-
39
-
-
45349109292
-
A cell-surface polymer reptation mechanism for tumor transendothelial transport of macromolecules
-
Uzgiris E. A cell-surface polymer reptation mechanism for tumor transendothelial transport of macromolecules. Technol Cancer Res T. 2008;7(3): 257-68.
-
(2008)
Technol Cancer Res T
, vol.7
, Issue.3
, pp. 257-268
-
-
Uzgiris, E.1
-
40
-
-
67650727594
-
Physiologic upper limit of pore size in the blood-tumor barrier of malignant solid tumors
-
Sarin H, Kanevsky AS, Wu H, Sousa AA, Wilson CM, Aronova MA, et al. Physiologic upper limit of pore size in the blood-tumor barrier of malignant solid tumors. J Transl Med. 2009;7(1): 51.
-
(2009)
J Transl Med
, vol.7
, Issue.1
, pp. 51
-
-
Sarin, H.1
Kanevsky, A.S.2
Wu, H.3
Sousa, A.A.4
Wilson, C.M.5
Aronova, M.A.6
|