Regulation of autophagy in rat hepatocytes treated in vitro with low concentration of mercury

Toxicological and Environmental Chemistry

Volumn 95, Issue 3, 2013, Pages 504-

  Chatterjee, Sarmishtha ^a   Nandi, Pratyusha ^a   Mukherjee, Sandip ^a   Chattopadhyay, Ansuman ^a   Bhattacharya, Shelley ^a  

^a VISVA BHARATI UNIVERSITY   (India)

Author keywords

autophagy; LC3B; lysosome; mercury; rat hepatocytes; ubiquitination

Indexed keywords

CHLORINE COMPOUNDS; DIGITAL STORAGE; MERCURY (METAL); MERCURY COMPOUNDS; PROTEINS; RATS;

AUTOPHAGY; LC3B; LYSOSOME; RAT HEPATOCYTES; UBIQUITINATION;

CELL DEATH;

CELL ORGANELLE; CONCENTRATION (COMPOSITION); ENZYME ACTIVITY; MERCURY (ELEMENT); PATHOLOGY; PHYSIOLOGICAL RESPONSE; PROTEIN; RODENT;

RATTUS;

EID: 84877828450     PISSN: 02772248     EISSN: 10290486     Source Type: Journal    
DOI: 10.1080/02772248.2013.786941     Document Type: Article

References (35)

1. ATSDR (Agency for Toxic Substances & Disease Registry) 1999. "Toxicological Profile for Mercury." CAS# 7439-97-6
2. Bode, A. M., and Z. Dong. 2002. "The Paradox of Arsenic: Molecular Mechanisms of Cell Transformation and Chemotherapeutic Effects." Critical Reviews in Oncology/Hematology 42: 5-24.
3. Bolt, M., R. M. Byrd, and W. T. Klimecki. 2010. "Autophagy is a Biological Target of Arsenic." In Arsenic in Geosphere and Human Diseases, edited by Jean, J. S., J. Bundschuh, and P. Bhattacharya,291-292. Boca Raton, FL: CRC Press.
4. Buege, J. A., and S. D. Aust. 1978. "Microsomal Lipid Peroxidation." Methods in Enzymology 52: 302.
5. Chargui, A., S. Zerki, G. Jacquillet, I. Rubera, M. Ilie, A. Belaid, C. Duranton, et al 2011. "Cadmium-induced Autophagy in Rat Kidney: An Early Biomarker of Subtoxic Exposure." Toxicological Sciences 121: 31-42.
6. Chatterjee, S., A. Ray, S. Mukherjee, S. Agarwal, R. Kundu, and S. Bhattacharya. 2012. "Low Concentration of Mercury Induces Autophagic Cell Death in Rat Hepatocytes." Toxicology and Industrial Health. doi:10.1177/0748233712462442.
7. Cullinan, S. B., J. D. Gordan, J. Jin, J. W. Harper, and J. A. Diehl. 2004. "The Keap1-BTB Protein is an Adaptor that Bridges Nrf2 to a Cul3-based E3 Ligase: Oxidative Stress Sensing by a Cul3-Keap1 Ligase." Molecular and Cellular Biology 24: 8477-8486.
8. Deretic, V. 2006. Autophagy in Immunity and Infection. Weinheim, Germany: Wiley-VCH.
9. Eskelinen, E. L., and P. Saftig. 2009. "Autophagy: A Lysosomal Degradation Pathway With a Central Role in Health and Disease." Biochimica et Biophysica Acta 1793: 664-673.
10. Fan, W., Z. Tang, D. Chen, D. Moughon, X. Ding, S. Chen, M. Zhu, and Q. Zhong. 2010. "Keap1 Facilitates p62-Mediated Ubiquitin Aggregate Clearance via Autophagy." Autophagy 6: 614-621.
11. Giansanti, V., A. Torriglia, and A. I. Scovassi. 2011. "Conversation Between Apoptosis and Autophagy: Is it Your Turn or Mine?"Apoptosis 16: 321-333.
12. Hoyvik, H., P. B. Gordon, T. O. Berg, P. E. Strmhaug, and P. O. Seglen. 1991. "Inhibition of Autophagic-lysosomal Delivery and Autophagic Lactolysis by Asparagine." Journal of Cell Biology 113: 1305-1312.
13. Ichimura, Y., and M. Komatsu. 2010. "Selective Degradation of p62 by Autophagy." Immunopathology 32: 431-436.
14. Itakura, E., and M. Noboru. 2011. "p62 Targeting to the Autophagosome Formation Site Requires Self-oligomerization but Not LC3B Binding." Journal of Cell Biology 192: 17-27.
15. Jung, C. H., S. H. Ro, J. Cao, N. M. Otto, and D. H. Kim. 2010. "mTOR Regulation of Autophagy." FEBS Letters 584: 1287-1295.
16. Kabeya, Y., N. Mizushima, T. Ueno, A. Yamamoto, T. Kirisako, T. Noda, E. Kominami, Y. Ohsumi, and T. Yoshimori. 2000. "LC3B, a Mammalian Homologue of Yeast Apg8, is Localized in Autophagosome Membranes After Processing." EMBO Journal 19: 5720-5728.
17. Kensler, T. W., N. Wakabayashi, and S. Biswal. 2007. "Cell Survival Responses to Environmental Stresses via the Keap1-Nrf2-ARE Pathway." Annual Review of Pharmacology and Toxicology 47: 89-116.
18. Kirkin, V., D. G. McEwan, I. Novak, and I. Dikic. 2009. "A Role for Ubiquitin in Selective Autophagy." Molecular Cell 34: 259-269.
19. Komatsu, M., H. Kurokawa, S. Waguri, K. Taguchi, A. Kobayashi, and Y. Ichimura. 2010. "The Selective Autophagy Substrate p62 Activates the Stress Responsive Transcription Factor Nrf2 Through Inactivation of Keap." Nature Cell Biology 12: 213-223.
20. Kopitz, J., G. O. Kisen, P. B. Gordon, P. Bohley, and P. O. Seglen. 1990. "Nonselective Autophagy of Cytosolic Enzymes in Isolated rat Hepatocytes." Journal of Cell Biology 111: 941-953.
21. Lau, A., X. J. Wang, F. Zhao, N. F. Villeneuve, T. Wu, T. Jiang, Z. Sun, E. White, and D. D. Zhang. 2010. "A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction Between Keap1 and p62." Molecular and Cell Biology 30: 3275-3285.
22. Lowry, O. H., N. J. Rosebrough, A. L. Farr, and R. J. Randall. 1951. "Measurement of Protein With the Folin Phenol Reagent." Biological Chemistry 193: 265-275.
23. Martin, P., M. C. Poggi, J. C. Chambard, K. E. Boulukos, and P. Pognonec 2006. "Low Dose Cadmium Poisoning Results in Sustained ERK Phosphorylation and Caspase Activation." Biochemical and Biophysical Research Communications 350: 803-807.
24. Noda, N. N., Y. Oshumi, and F. Inagaki. 2010. "ATG8-family Interacting Motif Crucial for Selective Autophagy." FEBS Letter 584: 1379-1385.
25. Ogata, T., Y. Oishi, M. Higuchi, and I. Muraoka. 2010. "Fasting-related Autophagic Response in Slow- and Fast-twitch Skeletal Muscle." Biochemical and Biophysical Research Communications 394: 136-140.
26. Pankiv, S., T. H. Clausen, T. Lamark, A. Brech, J. A. Bruun, H. Outzen, H. Øvervatn, G. Bjørkøy, and T. Johansen. 2007. "p62/SQSTM1 Binds Directly to ATG8/LC3B to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy." Biological Chemistry 282: 24131-24145.
27. 3 Toxicity in rat Hepatocytes: Manifestation of Caspase-mediated Apoptosis." Toxicology and Industrial Health 24: 643-653.
28. Reggiori, F., and D. J. Klinosky. 2002. "Autophagy in the Eukaryotic Cell." Eukaryotic Cell 1: 11-21.
29. Roy, S., and S. Bhattacharya. 2006. "Arsenic-induced Histopathology and Synthesis of Stress Proteins in Liver and Kidney of Channa punctatus." Ecotoxicology and Environmental Safety 65: 218-229.
30. Shimano, K., M. Satake, A. Okaya, J. Kitanaka, N. Kitanaka, and M. Takemura. 2003. "Hepatic Oval Cell Have the Side Population Phenotype Defined by Expression of ATP Binding Cassette Transporter ABCG2/BCRP." American Journal of Pathology 163: 3-9.
31. Sou, Y. S., S. Waguri, J. Iwata, T. Ueno, T. Fujimura, and T. Hara. 2008. "The ATG8 Conjugation System is Indispensable for Proper Development of Autophagic Isolation Membranes in Mice." Molecular and Cell Biology 19: 4762-4775.
32. Sridharan, S., K. Jain, and A. Basu. 2011. "Regulation of Autophagy by Kinases." Cancers 3: 2630-54.
33. Wang, C. W., and D. J. Klionsky. 2003. "The Molecular Mechanism of Autophagy." Molecular Medicine 9: 65-76.
34. Yogalingam, G., and A. M. Pendergast. 2008. "Abl Kinases Regulate Autophagy by Promoting the Trafficking and Function of Lysosomal Components." Journal of Biological Chemistry 283: 35941-35953.
35. Young, M. M., Y. Takahashi, O. Khan, S. Park, T. Hori, J. Yun, A. K. Sharma, et al 2012. "Autophagosomal Membrane Serves as Platform for Intracellular Death-inducing Signaling Complex (iDISC)-mediated Caspase-8 Activation and Apoptosis." Biological Chemistry 287: 12455-12468.