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Volumn 8, Issue 5, 2013, Pages

Three-Dimensional Collagen I Promotes Gemcitabine Resistance In Vitro in Pancreatic Cancer Cells through HMGA2-Dependent Histone Acetyltransferase Expression

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; E1A ASSOCIATED P300 PROTEIN; GEMCITABINE; HIGH MOBILITY GROUP A2 PROTEIN; HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE GCN5; HISTONE ACETYLTRANSFERASE PCAF; HISTONE H3; HISTONE H3K27; HISTONE H3K9; UNCLASSIFIED DRUG;

EID: 84877828072     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0064566     Document Type: Article
Times cited : (55)

References (51)
  • 2
    • 77951755278 scopus 로고    scopus 로고
    • Pancreatic cancer
    • Hidalgo M, (2010) Pancreatic cancer. N Engl J Med 362: 1605-1617.
    • (2010) N Engl J Med , vol.362 , pp. 1605-1617
    • Hidalgo, M.1
  • 4
    • 84555178641 scopus 로고    scopus 로고
    • Biochemical role of the collagen-rich tumor microenvironment in pancreatic cancer progression
    • Shields MA, Dangi-Garimella S, Redig AJ, Munshi HG, (2012) Biochemical role of the collagen-rich tumor microenvironment in pancreatic cancer progression. Biochem J 441: 541-552.
    • (2012) Biochem J , vol.441 , pp. 541-552
    • Shields, M.A.1    Dangi-Garimella, S.2    Redig, A.J.3    Munshi, H.G.4
  • 5
    • 33746882751 scopus 로고    scopus 로고
    • Extracellular matrix-mediated membrane-type 1 matrix metalloproteinase expression in pancreatic ductal cells is regulated by transforming growth factor-beta1
    • Ottaviano AJ, Sun L, Ananthanarayanan V, Munshi HG, (2006) Extracellular matrix-mediated membrane-type 1 matrix metalloproteinase expression in pancreatic ductal cells is regulated by transforming growth factor-beta1. Cancer Res 66: 7032-7040.
    • (2006) Cancer Res , vol.66 , pp. 7032-7040
    • Ottaviano, A.J.1    Sun, L.2    Ananthanarayanan, V.3    Munshi, H.G.4
  • 6
    • 79551509386 scopus 로고    scopus 로고
    • Three-Dimensional Collagen I Promotes Gemcitabine Resistance in Pancreatic Cancer through MT1-MMP-Mediated Expression of HMGA2
    • Dangi-Garimella S, Krantz SB, Barron MR, Shields MA, Heiferman MJ, et al. (2011) Three-Dimensional Collagen I Promotes Gemcitabine Resistance in Pancreatic Cancer through MT1-MMP-Mediated Expression of HMGA2. Cancer Res 71: 1019-1028.
    • (2011) Cancer Res , vol.71 , pp. 1019-1028
    • Dangi-Garimella, S.1    Krantz, S.B.2    Barron, M.R.3    Shields, M.A.4    Heiferman, M.J.5
  • 7
    • 67149143399 scopus 로고    scopus 로고
    • Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
    • Olive KP, Jacobetz MA, Davidson CJ, Gopinathan A, McIntyre D, et al. (2009) Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. Science 324: 1457-1461.
    • (2009) Science , vol.324 , pp. 1457-1461
    • Olive, K.P.1    Jacobetz, M.A.2    Davidson, C.J.3    Gopinathan, A.4    McIntyre, D.5
  • 8
    • 84858602107 scopus 로고    scopus 로고
    • Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma
    • Provenzano PP, Cuevas C, Chang AE, Goel VK, Von Hoff DD, et al. (2012) Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma. Cancer Cell 21: 418-429.
    • (2012) Cancer Cell , vol.21 , pp. 418-429
    • Provenzano, P.P.1    Cuevas, C.2    Chang, A.E.3    Goel, V.K.4    Von Hoff, D.D.5
  • 9
    • 84870909412 scopus 로고    scopus 로고
    • Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
    • Jacobetz MA, Chan DS, Neesse A, Bapiro TE, Cook N, et al. (2012) Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer. Gut.
    • (2012) Gut
    • Jacobetz, M.A.1    Chan, D.S.2    Neesse, A.3    Bapiro, T.E.4    Cook, N.5
  • 10
    • 70349613017 scopus 로고    scopus 로고
    • The high mobility group protein HMGA2: a co-regulator of chromatin structure and pluripotency in stem cells?
    • Pfannkuche K, Summer H, Li O, Hescheler J, Droge P, (2009) The high mobility group protein HMGA2: a co-regulator of chromatin structure and pluripotency in stem cells? Stem Cell Rev 5: 224-230.
    • (2009) Stem Cell Rev , vol.5 , pp. 224-230
    • Pfannkuche, K.1    Summer, H.2    Li, O.3    Hescheler, J.4    Droge, P.5
  • 11
    • 36448992338 scopus 로고    scopus 로고
    • Roles of HMGA proteins in cancer
    • Fusco A, Fedele M, (2007) Roles of HMGA proteins in cancer. Nat Rev Cancer 7: 899-910.
    • (2007) Nat Rev Cancer , vol.7 , pp. 899-910
    • Fusco, A.1    Fedele, M.2
  • 12
    • 58149148165 scopus 로고    scopus 로고
    • HMGA2 protein expression correlates with lymph node metastasis and increased tumor grade in pancreatic ductal adenocarcinoma
    • Hristov AC, Cope L, Reyes MD, Singh M, Iacobuzio-Donahue C, et al. (2009) HMGA2 protein expression correlates with lymph node metastasis and increased tumor grade in pancreatic ductal adenocarcinoma. Mod Pathol 22: 43-49.
    • (2009) Mod Pathol , vol.22 , pp. 43-49
    • Hristov, A.C.1    Cope, L.2    Reyes, M.D.3    Singh, M.4    Iacobuzio-Donahue, C.5
  • 13
    • 84856296152 scopus 로고    scopus 로고
    • HMGA1 and HMGA2 protein expression correlates with advanced tumour grade and lymph node metastasis in pancreatic adenocarcinoma
    • Piscuoglio S, Zlobec I, Pallante P, Sepe R, Esposito F, et al. (2012) HMGA1 and HMGA2 protein expression correlates with advanced tumour grade and lymph node metastasis in pancreatic adenocarcinoma. Histopathology 60: 397-404.
    • (2012) Histopathology , vol.60 , pp. 397-404
    • Piscuoglio, S.1    Zlobec, I.2    Pallante, P.3    Sepe, R.4    Esposito, F.5
  • 14
    • 50249175130 scopus 로고    scopus 로고
    • Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers
    • Wei Y, Xia W, Zhang Z, Liu J, Wang H, et al. (2008) Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers. Mol Carcinog 47: 701-706.
    • (2008) Mol Carcinog , vol.47 , pp. 701-706
    • Wei, Y.1    Xia, W.2    Zhang, Z.3    Liu, J.4    Wang, H.5
  • 15
    • 77950510166 scopus 로고    scopus 로고
    • Cellular histone modification patterns predict prognosis and treatment response in resectable pancreatic adenocarcinoma: results from RTOG 9704
    • Manuyakorn A, Paulus R, Farrell J, Dawson NA, Tze S, et al. (2010) Cellular histone modification patterns predict prognosis and treatment response in resectable pancreatic adenocarcinoma: results from RTOG 9704. J Clin Oncol 28: 1358-1365.
    • (2010) J Clin Oncol , vol.28 , pp. 1358-1365
    • Manuyakorn, A.1    Paulus, R.2    Farrell, J.3    Dawson, N.A.4    Tze, S.5
  • 17
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone-modification maps
    • Esteller M, (2007) Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genet 8: 286-298.
    • (2007) Nat Rev Genet , vol.8 , pp. 286-298
    • Esteller, M.1
  • 18
    • 67649305191 scopus 로고    scopus 로고
    • Epigenetics in cancer: targeting chromatin modifications
    • Ellis L, Atadja PW, Johnstone RW, (2009) Epigenetics in cancer: targeting chromatin modifications. Mol Cancer Ther 8: 1409-1420.
    • (2009) Mol Cancer Ther , vol.8 , pp. 1409-1420
    • Ellis, L.1    Atadja, P.W.2    Johnstone, R.W.3
  • 19
    • 56249097914 scopus 로고    scopus 로고
    • Chromatin-modifying enzymes as therapeutic targets - Part 2
    • Keppler BR, Archer TK, (2008) Chromatin-modifying enzymes as therapeutic targets - Part 2. Expert Opin Ther Targets 12: 1457-1467.
    • (2008) Expert Opin Ther Targets , vol.12 , pp. 1457-1467
    • Keppler, B.R.1    Archer, T.K.2
  • 20
    • 56249097914 scopus 로고    scopus 로고
    • Chromatin-modifying enzymes as therapeutic targets - Part 1
    • Keppler BR, Archer TK, (2008) Chromatin-modifying enzymes as therapeutic targets - Part 1. Expert Opin Ther Targets 12: 1301-1312.
    • (2008) Expert Opin Ther Targets , vol.12 , pp. 1301-1312
    • Keppler, B.R.1    Archer, T.K.2
  • 21
    • 79956192290 scopus 로고    scopus 로고
    • Acetylation as a transcriptional control mechanism-HDACs and HATs in pancreatic ductal adenocarcinoma
    • Schneider G, Kramer OH, Schmid RM, Saur D, (2011) Acetylation as a transcriptional control mechanism-HDACs and HATs in pancreatic ductal adenocarcinoma. J Gastrointest Cancer 42: 85-92.
    • (2011) J Gastrointest Cancer , vol.42 , pp. 85-92
    • Schneider, G.1    Kramer, O.H.2    Schmid, R.M.3    Saur, D.4
  • 22
    • 70349311616 scopus 로고    scopus 로고
    • Histone acetyl transferases as emerging drug targets
    • Dekker FJ, Haisma HJ, (2009) Histone acetyl transferases as emerging drug targets. Drug Discov Today 14: 942-948.
    • (2009) Drug Discov Today , vol.14 , pp. 942-948
    • Dekker, F.J.1    Haisma, H.J.2
  • 23
    • 77249176619 scopus 로고    scopus 로고
    • NFAT-induced histone acetylation relay switch promotes c-Myc-dependent growth in pancreatic cancer cells
    • Koenig A, Linhart T, Schlengemann K, Reutlinger K, Wegele J, et al. (2010) NFAT-induced histone acetylation relay switch promotes c-Myc-dependent growth in pancreatic cancer cells. Gastroenterology 138: 1189-1199 e1181-1182.
    • (2010) Gastroenterology , vol.138
    • Koenig, A.1    Linhart, T.2    Schlengemann, K.3    Reutlinger, K.4    Wegele, J.5
  • 24
    • 0036829085 scopus 로고    scopus 로고
    • Down-regulation of p300/CBP histone acetyltransferase activates a senescence checkpoint in human melanocytes
    • Bandyopadhyay D, Okan NA, Bales E, Nascimento L, Cole PA, et al. (2002) Down-regulation of p300/CBP histone acetyltransferase activates a senescence checkpoint in human melanocytes. Cancer Res 62: 6231-6239.
    • (2002) Cancer Res , vol.62 , pp. 6231-6239
    • Bandyopadhyay, D.1    Okan, N.A.2    Bales, E.3    Nascimento, L.4    Cole, P.A.5
  • 25
    • 78751611793 scopus 로고    scopus 로고
    • Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation
    • Jin Q, Yu LR, Wang L, Zhang Z, Kasper LH, et al. (2011) Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation. EMBO J 30: 249-262.
    • (2011) EMBO J , vol.30 , pp. 249-262
    • Jin, Q.1    Yu, L.R.2    Wang, L.3    Zhang, Z.4    Kasper, L.H.5
  • 27
    • 79955613209 scopus 로고    scopus 로고
    • Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors
    • Ogiwara H, Ui A, Otsuka A, Satoh H, Yokomi I, et al. (2011) Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors. Oncogene 30: 2135-2146.
    • (2011) Oncogene , vol.30 , pp. 2135-2146
    • Ogiwara, H.1    Ui, A.2    Otsuka, A.3    Satoh, H.4    Yokomi, I.5
  • 28
    • 79952342432 scopus 로고    scopus 로고
    • GCN5 and E2F1 stimulate nucleotide excision repair by promoting H3K9 acetylation at sites of damage
    • Guo R, Chen J, Mitchell DL, Johnson DG, (2011) GCN5 and E2F1 stimulate nucleotide excision repair by promoting H3K9 acetylation at sites of damage. Nucleic Acids Res 39: 1390-1397.
    • (2011) Nucleic Acids Res , vol.39 , pp. 1390-1397
    • Guo, R.1    Chen, J.2    Mitchell, D.L.3    Johnson, D.G.4
  • 30
    • 79960065049 scopus 로고    scopus 로고
    • HMGA proteins promote ATM expression and enhance cancer cell resistance to genotoxic agents
    • Palmieri D, Valentino T, D'Angelo D, De Martino I, Postiglione I, et al. (2011) HMGA proteins promote ATM expression and enhance cancer cell resistance to genotoxic agents. Oncogene 30: 3024-3035.
    • (2011) Oncogene , vol.30 , pp. 3024-3035
    • Palmieri, D.1    Valentino, T.2    D'Angelo, D.3    De Martino, I.4    Postiglione, I.5
  • 31
    • 84863985549 scopus 로고    scopus 로고
    • Genome-wide analysis of HMGA2 transcription factor binding sites by ChIP on chip in gastric carcinoma cells
    • Zha L, Wang Z, Tang W, Zhang N, Liao G, et al. (2012) Genome-wide analysis of HMGA2 transcription factor binding sites by ChIP on chip in gastric carcinoma cells. Mol Cell Biochem 364: 243-251.
    • (2012) Mol Cell Biochem , vol.364 , pp. 243-251
    • Zha, L.1    Wang, Z.2    Tang, W.3    Zhang, N.4    Liao, G.5
  • 32
    • 79959419265 scopus 로고    scopus 로고
    • High-mobility group A2 protein modulates hTERT transcription to promote tumorigenesis
    • Li AY, Lin HH, Kuo CY, Shih HM, Wang CC, et al. (2011) High-mobility group A2 protein modulates hTERT transcription to promote tumorigenesis. Mol Cell Biol 31: 2605-2617.
    • (2011) Mol Cell Biol , vol.31 , pp. 2605-2617
    • Li, A.Y.1    Lin, H.H.2    Kuo, C.Y.3    Shih, H.M.4    Wang, C.C.5
  • 33
    • 84871724355 scopus 로고    scopus 로고
    • HMGA2 regulates the in vitro aging and proliferation of human umbilical cord blood-derived stromal cells through the mTOR/p70S6K signaling pathway
    • Yu KR, Park SB, Jung JW, Seo MS, Hong IS, et al. (2013) HMGA2 regulates the in vitro aging and proliferation of human umbilical cord blood-derived stromal cells through the mTOR/p70S6K signaling pathway. Stem Cell Res 10: 156-165.
    • (2013) Stem Cell Res , vol.10 , pp. 156-165
    • Yu, K.R.1    Park, S.B.2    Jung, J.W.3    Seo, M.S.4    Hong, I.S.5
  • 34
    • 41149162821 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor-1alpha, histone deacetylase 1, and metastasis-associated protein 1 in pancreatic carcinoma: correlation with poor prognosis with possible regulation
    • Miyake K, Yoshizumi T, Imura S, Sugimoto K, Batmunkh E, et al. (2008) Expression of hypoxia-inducible factor-1alpha, histone deacetylase 1, and metastasis-associated protein 1 in pancreatic carcinoma: correlation with poor prognosis with possible regulation. Pancreas 36: e1-9.
    • (2008) Pancreas , vol.36
    • Miyake, K.1    Yoshizumi, T.2    Imura, S.3    Sugimoto, K.4    Batmunkh, E.5
  • 35
    • 48149115853 scopus 로고    scopus 로고
    • High histone deacetylase 7 (HDAC7) expression is significantly associated with adenocarcinomas of the pancreas
    • Ouaissi M, Sielezneff I, Silvestre R, Sastre B, Bernard JP, et al. (2008) High histone deacetylase 7 (HDAC7) expression is significantly associated with adenocarcinomas of the pancreas. Ann Surg Oncol 15: 2318-2328.
    • (2008) Ann Surg Oncol , vol.15 , pp. 2318-2328
    • Ouaissi, M.1    Sielezneff, I.2    Silvestre, R.3    Sastre, B.4    Bernard, J.P.5
  • 36
    • 84871273907 scopus 로고    scopus 로고
    • Class I and class II histone deacetylases are potential therapeutic targets for treating pancreatic cancer
    • Wang G, He J, Zhao J, Yun W, Xie C,et al. Class I and class II histone deacetylases are potential therapeutic targets for treating pancreatic cancer. PLoS One 7: e52095.
    • PLoS One , vol.7
    • Wang, G.1    He, J.2    Zhao, J.3    Yun, W.4    Xie, C.5
  • 37
    • 77952847488 scopus 로고    scopus 로고
    • Three-dimensional cell growth confers radioresistance by chromatin density modification
    • Storch K, Eke I, Borgmann K, Krause M, Richter C, et al. (2010) Three-dimensional cell growth confers radioresistance by chromatin density modification. Cancer Res 70: 3925-3934.
    • (2010) Cancer Res , vol.70 , pp. 3925-3934
    • Storch, K.1    Eke, I.2    Borgmann, K.3    Krause, M.4    Richter, C.5
  • 38
    • 0016291837 scopus 로고
    • Intranuclear distribution of DNA repair synthesis induced by chemical carcinogens or ultraviolet light in human diploid fibroblasts
    • Harris CC, Connor RJ, Jackson FE, Lieberman MW, (1974) Intranuclear distribution of DNA repair synthesis induced by chemical carcinogens or ultraviolet light in human diploid fibroblasts. Cancer Res 34: 3461-3468.
    • (1974) Cancer Res , vol.34 , pp. 3461-3468
    • Harris, C.C.1    Connor, R.J.2    Jackson, F.E.3    Lieberman, M.W.4
  • 39
    • 34748902384 scopus 로고    scopus 로고
    • Global chromatin compaction limits the strength of the DNA damage response
    • Murga M, Jaco I, Fan Y, Soria R, Martinez-Pastor B, et al. (2007) Global chromatin compaction limits the strength of the DNA damage response. J Cell Biol 178: 1101-1108.
    • (2007) J Cell Biol , vol.178 , pp. 1101-1108
    • Murga, M.1    Jaco, I.2    Fan, Y.3    Soria, R.4    Martinez-Pastor, B.5
  • 40
    • 79952262759 scopus 로고    scopus 로고
    • Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy
    • Wagner JM, Hackanson B, Lubbert M, Jung M, (2010) Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy. Clin Epigenetics 1: 117-136.
    • (2010) Clin Epigenetics , vol.1 , pp. 117-136
    • Wagner, J.M.1    Hackanson, B.2    Lubbert, M.3    Jung, M.4
  • 41
    • 78650723028 scopus 로고    scopus 로고
    • Rationale for possible targeting of histone deacetylase signaling in cancer diseases with a special reference to pancreatic cancer
    • Ouaissi M, Giger U, Sielezneff I, Pirro N, Sastre B, et al. (2011) Rationale for possible targeting of histone deacetylase signaling in cancer diseases with a special reference to pancreatic cancer. J Biomed Biotechnol 2011: 315939.
    • (2011) J Biomed Biotechnol , vol.2011 , pp. 315939
    • Ouaissi, M.1    Giger, U.2    Sielezneff, I.3    Pirro, N.4    Sastre, B.5
  • 42
    • 80053144962 scopus 로고    scopus 로고
    • A decade of exploring the cancer epigenome - biological and translational implications
    • Baylin SB, Jones PA, (2011) A decade of exploring the cancer epigenome - biological and translational implications. Nat Rev Cancer 11: 726-734.
    • (2011) Nat Rev Cancer , vol.11 , pp. 726-734
    • Baylin, S.B.1    Jones, P.A.2
  • 43
    • 33745629366 scopus 로고    scopus 로고
    • Gemcitabine plus CI-994 offers no advantage over gemcitabine alone in the treatment of patients with advanced pancreatic cancer: results of a phase II randomized, double-blind, placebo-controlled, multicenter study
    • Richards DA, Boehm KA, Waterhouse DM, Wagener DJ, Krishnamurthi SS, et al. (2006) Gemcitabine plus CI-994 offers no advantage over gemcitabine alone in the treatment of patients with advanced pancreatic cancer: results of a phase II randomized, double-blind, placebo-controlled, multicenter study. Ann Oncol 17: 1096-1102.
    • (2006) Ann Oncol , vol.17 , pp. 1096-1102
    • Richards, D.A.1    Boehm, K.A.2    Waterhouse, D.M.3    Wagener, D.J.4    Krishnamurthi, S.S.5
  • 44
    • 34748861551 scopus 로고    scopus 로고
    • Characterization of novel inhibitors of histone acetyltransferases
    • Eliseeva ED, Valkov V, Jung M, Jung MO, (2007) Characterization of novel inhibitors of histone acetyltransferases. Mol Cancer Ther 6: 2391-2398.
    • (2007) Mol Cancer Ther , vol.6 , pp. 2391-2398
    • Eliseeva, E.D.1    Valkov, V.2    Jung, M.3    Jung, M.O.4
  • 45
    • 77954204335 scopus 로고    scopus 로고
    • Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor
    • Bowers EM, Yan G, Mukherjee C, Orry A, Wang L, et al. (2010) Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor. Chem Biol 17: 471-482.
    • (2010) Chem Biol , vol.17 , pp. 471-482
    • Bowers, E.M.1    Yan, G.2    Mukherjee, C.3    Orry, A.4    Wang, L.5
  • 46
    • 80052707789 scopus 로고    scopus 로고
    • Inhibition of the acetyltransferases p300 and CBP reveals a targetable function for p300 in the survival and invasion pathways of prostate cancer cell lines
    • Santer FR, Hoschele PP, Oh SJ, Erb HH, Bouchal J, et al. (2011) Inhibition of the acetyltransferases p300 and CBP reveals a targetable function for p300 in the survival and invasion pathways of prostate cancer cell lines. Mol Cancer Ther 10: 1644-1655.
    • (2011) Mol Cancer Ther , vol.10 , pp. 1644-1655
    • Santer, F.R.1    Hoschele, P.P.2    Oh, S.J.3    Erb, H.H.4    Bouchal, J.5
  • 47
    • 77956238502 scopus 로고    scopus 로고
    • Rho-ROCK-myosin signaling mediates membrane type 1 matrix metalloproteinase-induced cellular aggregation of keratinocytes
    • Dangi-Garimella S, Redig AJ, Shields MA, Siddiqui MA, Munshi HG, (2010) Rho-ROCK-myosin signaling mediates membrane type 1 matrix metalloproteinase-induced cellular aggregation of keratinocytes. J Biol Chem 285: 28363-28372.
    • (2010) J Biol Chem , vol.285 , pp. 28363-28372
    • Dangi-Garimella, S.1    Redig, A.J.2    Shields, M.A.3    Siddiqui, M.A.4    Munshi, H.G.5
  • 48
    • 79953230450 scopus 로고    scopus 로고
    • Pancreatic Cancer Cells Respond to Type I Collagen by Inducing Snail Expression to Promote Membrane Type 1 Matrix Metalloproteinase-dependent Collagen Invasion
    • Shields MA, Dangi-Garimella S, Krantz SB, Bentrem DJ, Munshi HG, (2011) Pancreatic Cancer Cells Respond to Type I Collagen by Inducing Snail Expression to Promote Membrane Type 1 Matrix Metalloproteinase-dependent Collagen Invasion. J Biol Chem 286: 10495-10504.
    • (2011) J Biol Chem , vol.286 , pp. 10495-10504
    • Shields, M.A.1    Dangi-Garimella, S.2    Krantz, S.B.3    Bentrem, D.J.4    Munshi, H.G.5
  • 49
    • 84857466746 scopus 로고    scopus 로고
    • Interplay between beta1-Integrin and Rho Signaling Regulates Differential Scattering and Motility of Pancreatic Cancer Cells by Snail and Slug Proteins
    • Shields MA, Krantz SB, Bentrem DJ, Dangi-Garimella S, Munshi HG, (2012) Interplay between beta1-Integrin and Rho Signaling Regulates Differential Scattering and Motility of Pancreatic Cancer Cells by Snail and Slug Proteins. J Biol Chem 287: 6218-6229.
    • (2012) J Biol Chem , vol.287 , pp. 6218-6229
    • Shields, M.A.1    Krantz, S.B.2    Bentrem, D.J.3    Dangi-Garimella, S.4    Munshi, H.G.5
  • 50
    • 4644356493 scopus 로고    scopus 로고
    • Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth factor-beta1-induced pericellular collagenolysis
    • Munshi HG, Wu YI, Mukhopadhyay S, Ottaviano AJ, Sassano A, et al. (2004) Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth factor-beta1-induced pericellular collagenolysis. J Biol Chem 279: 39042-39050.
    • (2004) J Biol Chem , vol.279 , pp. 39042-39050
    • Munshi, H.G.1    Wu, Y.I.2    Mukhopadhyay, S.3    Ottaviano, A.J.4    Sassano, A.5
  • 51
    • 79952005676 scopus 로고    scopus 로고
    • Collagen regulation of let-7 in pancreatic cancer involves TGF-beta1-mediated membrane type 1-matrix metalloproteinase expression
    • Dangi-Garimella S, Strouch MJ, Grippo PJ, Bentrem DJ, Munshi HG, (2011) Collagen regulation of let-7 in pancreatic cancer involves TGF-beta1-mediated membrane type 1-matrix metalloproteinase expression. Oncogene 30: 1002-1008.
    • (2011) Oncogene , vol.30 , pp. 1002-1008
    • Dangi-Garimella, S.1    Strouch, M.J.2    Grippo, P.J.3    Bentrem, D.J.4    Munshi, H.G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.