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Volumn 15, Issue 3, 2013, Pages 215-223

Obesity and metabolic syndrome in kidney transplantation

Author keywords

Belatacept; Body mass index; Calcineurin inhibitor; Cardiovascular disease; Chronic allograft nephropathy; Corticosteroids; Graft loss; Hypertension; Immunosuppressive therapy; Mammalian target of rapamycin (mTOR) inhibitor; Metabolic syndrome; New onset diabetes after transplant; Obesity; Patient survival; Renal transplantation

Indexed keywords

BELATACEPT; CALCINEURIN INHIBITOR; CORTICOSTEROID; CYCLOPHOSPHAMIDE; CYCLOSPORIN; EVEROLIMUS; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RAPAMYCIN; TACROLIMUS;

EID: 84877820389     PISSN: 15226417     EISSN: 15343111     Source Type: Journal    
DOI: 10.1007/s11906-013-0335-6     Document Type: Article
Times cited : (24)

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    • 10.1111/j.1600-6143.2011.03914.x This study compared a traditional cyclosporine-based regimen with the new biologic agent beletacept in patients who had received extended criteria donor kidney transplants. They found that the belatecept group had a mean calculated GFR 11 ml/min higher than the cyclosporine treatment group at 3 years and that there was no increased risk of rejection
    • • Jo P, Grinyo JM, Vanrenterghem Y, et al. Three year outcomes from BENEFIT-EXT: a phase III study of belatacept versus cyclosporine in recipients of extended criteria donor kidneys. Am J Transplant. 2012;12(3):630-9. This study compared a traditional cyclosporine-based regimen with the new biologic agent beletacept in patients who had received extended criteria donor kidney transplants. They found that the belatecept group had a mean calculated GFR 11 ml/min higher than the cyclosporine treatment group at 3 years and that there was no increased risk of rejection.
    • (2012) Am J Transplant , vol.12 , Issue.3 , pp. 630-639
    • Jo, P.1    Grinyo, J.M.2    Vanrenterghem, Y.3
  • 95
    • 79955544132 scopus 로고    scopus 로고
    • Belatacept-based regimens are associated with improved cardiovascular and metabolic risk factors compared with cyclosporine in kidney transplant recipients
    • 21372756 10.1097/TP.0b013e31820c10eb 1:CAS:528:DC%2BC3MXkvF2itr4%3D This study analyzed the data from the BENEFIT and BENEFIT-EXT studies specifically looking at cardiacvascular and metabolic endpoints. It was shown that at 12 months, the belatacept regimens were associated with lower blood pressure and lipid levels than the cyclosporine-based therapy. There was a lower incident of new-onset diabetes after transplant (NODAT) in the belatacept group
    • • Vanrenterghem Y, Bresnahan B, Campistol J, et al. Belatacept-based regimens are associated with improved cardiovascular and metabolic risk factors compared with cyclosporine in kidney transplant recipients. Transplantation. 2011;91(9):976-83. This study analyzed the data from the BENEFIT and BENEFIT-EXT studies specifically looking at cardiacvascular and metabolic endpoints. It was shown that at 12 months, the belatacept regimens were associated with lower blood pressure and lipid levels than the cyclosporine-based therapy. There was a lower incident of new-onset diabetes after transplant (NODAT) in the belatacept group.
    • (2011) Transplantation , vol.91 , Issue.9 , pp. 976-983
    • Vanrenterghem, Y.1    Bresnahan, B.2    Campistol, J.3


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