Synthesis and biological evaluation against Leishmania amazonensis of a series of alkyl-substituted benzophenones

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 11, 2013, Pages 3114-3119

  MacIel Rezende, Claudia Mara ^a   De Almeida, Letícia ^a   Costa, Éderson D'Martin ^a   Pires, Francieli Ribeiro ^a   Alves, Karina Ferreira ^a   Junior, Cláudio Viegas ^a,b   Dias, Danielle Ferreira ^a,b   Doriguetto, Antônio Carlos ^b   Marques, Marcos José ^a   Dos Santos, Marcelo Henrique ^a  

^a FEDERAL UNIVERSITY OF ALFENAS   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Benzophenone derivatives; Leishmania amazonensis; Leishmaniasis

Indexed keywords

2 HYDROXY 4 O (3,3 DIMETHYL)ALLYLBENZOPHENONE; 2 HYDROXY 4 O BUTYLBENZOPHENONE; 2,4' DIHYDROXYBENZOPHENONE; 2,4' DIHYDROXYBENZOPHENONE DERIVATIVE; 4 BUTOXYBENZOPHENONE; 4 METHOXYBENZOPHENONE; 4 O (3,3 DIMETHYL)ALLYLBENZOPHENONE; 4,4' DI BUTOXYBENZOPHENONE; 4,4' DI METHOXYBENZOPHENONE; 4,4' DI O (3,3 DIMETHYL)ALLYLBENZOPHENONE; 4,E4,4' DIHYDROXYBENZOPHENONE DERIVATIVE; ALKYL SUBSTITUTED BENZOPHENONE DERIVATIVE; AMPHOTERICIN B; BENZOPHENONE DERIVATIVE; LFQM 115; LFQM 116; LFQM 117; LFQM 118; LFQM 119; LFQM 120; LFQM 121; LFQM 122; LFQM 123; OXYBENZONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SYNTHESIS; IC 50; LEISHMANIA; LIPOPHILICITY; MACROPHAGE; MEMBRANE PERMEABILITY; MOUSE; NONHUMAN; PROMASTIGOTE;

AMPHOTERICIN B; ANIMALS; BENZOPHENONES; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; CELLS, CULTURED; LEISHMANIA MEXICANA; LIFE CYCLE STAGES; MACROPHAGES, PERITONEAL; MICE; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS;

LEISHMANIA AMAZONENSIS; MURINAE; PROTOZOA;

EID: 84877813729     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.03.045     Document Type: Article

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