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Volumn 280, Issue 10, 2013, Pages 2462-2470

Glycosaminoglycans are functional ligands for receptor for advanced glycation end-products in tumors

Author keywords

chondroitin sulfate; dermatan sulfate; GalNAc 4 sulfate 6 O sulfotransferase; heparan sulfate; Lewis lung carcinoma; proteoglycan; receptor for advanced glycation end products; tumor metastasis

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; CHONDROITIN SULFATE; DERMATAN SULFATE; GLUCURONIC ACID; GLYCOSAMINOGLYCAN; HEPARAN SULFATE; N ACETYLGALACTOSAMINE; PROTEOGLYCAN;

EID: 84877707810     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12156     Document Type: Review
Times cited : (57)

References (64)
  • 2
    • 35548984829 scopus 로고    scopus 로고
    • Chondroitin/dermatan sulfate in the central nervous system
    • DOI 10.1016/j.sbi.2007.08.015, PII S0959440X07001224, Carbohydrates and glycoconjugates / Biophysical methods
    • Sugahara K, &, Mikami T, (2007) Chondroitin/dermatan sulfate in the central nervous system. Curr Opin Struct Biol 17, 536-545. (Pubitemid 350019013)
    • (2007) Current Opinion in Structural Biology , vol.17 , Issue.5 , pp. 536-545
    • Sugahara, K.1    Mikami, T.2
  • 3
    • 34247610845 scopus 로고    scopus 로고
    • Heparan sulphate proteoglycans fine-tune mammalian physiology
    • DOI 10.1038/nature05817, PII NATURE05817
    • Bishop JR, Schuksz M, &, Esko JD, (2007) Heparan sulphate proteoglycans fine-tune mammalian physiology. Nature 446, 1030-1037. (Pubitemid 46676065)
    • (2007) Nature , vol.446 , Issue.7139 , pp. 1030-1037
    • Bishop, J.R.1    Schuksz, M.2    Esko, J.D.3
  • 4
    • 21744431575 scopus 로고    scopus 로고
    • The sweet and sour of cancer: Glycans as novel therapeutic targets
    • DOI 10.1038/nrc1649
    • Fuster MM, &, Esko JD, (2005) The sweet and sour of cancer: glycans as novel therapeutic targets. Nat Rev Cancer 5, 526-542. (Pubitemid 40942829)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.7 , pp. 526-542
    • Fuster, M.M.1    Esko, J.D.2
  • 8
    • 0032488902 scopus 로고    scopus 로고
    • Characteristic hexasaccharide sequences in octasaccharides derived from shark cartilage chondroitin sulfate D with a neurite outgrowth promoting activity
    • DOI 10.1074/jbc.273.6.3296
    • Nadanaka S, Clement A, Masayama K, Faissner A, &, Sugahara K, (1998) Characteristic hexasaccharide sequences in octasaccharides derived from shark cartilage chondroitin sulfate D with neurite outgrowth promoting activity. J Biol Chem 273, 3296-3307. (Pubitemid 28109743)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.6 , pp. 3296-3307
    • Nadanaka, S.1    Clement, A.2    Masayama, K.3    Faissner, A.4    Sugahara, K.5
  • 9
    • 0032561202 scopus 로고    scopus 로고
    • The DSD-1 carbohydrate epitope depends on sulfation, correlates with chondroitin sulfate D motifs, and is sufficient to promote neurite outgrowth
    • DOI 10.1074/jbc.273.43.28444
    • Clement AM, Nadanaka S, Masayama K, Mandl C, Sugahara K, &, Faissner A, (1998) The DSD-1-epitope depends on sulfation, correlates with chondroitin sulfate D motifs, and is sufficient to promote neurite outgrowth. J Biol Chem 273, 28444-28453. (Pubitemid 28496150)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.43 , pp. 28444-28453
    • Clement, A.M.1    Nadanaka, S.2    Masayama, K.3    Mandl, C.4    Sugahara, K.5    Faissner, A.6
  • 10
    • 33846010772 scopus 로고    scopus 로고
    • Chondroitin 4-O-sulfotransferase-1 regulates E disaccharide expression of chondroitin sulfate required for herpes simplex virus infectivity
    • DOI 10.1074/jbc.M609320200
    • Uyama T, Ishida M, Izumikawa T, Trybala E, Tufaro F, Bergström T, Sugahara K, &, Kitagawa H, (2006) Chondroitin 4-O-sulfotransferase-1 regulates E disaccharide expression of chondroitin sulfate required for herpes simplex virus infectivity. J Biol Chem 281, 38668-38674. (Pubitemid 46041992)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.50 , pp. 38668-38674
    • Uyama, T.1    Ishida, M.2    Izumikawa, T.3    Trybala, E.4    Tufaro, F.5    Bergstrom, T.6    Sugahara, K.7    Kitagawa, H.8
  • 13
    • 70449112926 scopus 로고    scopus 로고
    • Dermatan sulfate epimerase 1-deficient mice have reduced content and changed distribution of iduronic acids in dermatan sulfate and an altered collagen structure in skin
    • Maccarana M, Kalamajski S, Kongsgaard M, Magnusson SP, Oldberg A, &, Malmström A, (2009) Dermatan sulfate epimerase 1-deficient mice have reduced content and changed distribution of iduronic acids in dermatan sulfate and an altered collagen structure in skin. Mol Cell Biol 29, 5517-5528.
    • (2009) Mol Cell Biol , vol.29 , pp. 5517-5528
    • MacCarana, M.1    Kalamajski, S.2    Kongsgaard, M.3    Magnusson, S.P.4    Oldberg, A.5    Malmström, A.6
  • 16
    • 84865684271 scopus 로고    scopus 로고
    • Highly sulfated chondroitin sulfates, a novel class of prognostic biomarkers in ovarian cancer tissue
    • Vallen MJ, Massuger LF, ten Dam GB, Bulten J, &, van Kuppevelt TH, (2012) Highly sulfated chondroitin sulfates, a novel class of prognostic biomarkers in ovarian cancer tissue. Gynecol Oncol 127, 202-209.
    • (2012) Gynecol Oncol , vol.127 , pp. 202-209
    • Vallen, M.J.1    Massuger, L.F.2    Ten Dam, G.B.3    Bulten, J.4    Van Kuppevelt, T.H.5
  • 18
    • 84861742380 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products (RAGE) functions as a receptor for specific sulfated glycosaminoglycans, and anti-RAGE antibody or the sulfated glycosaminoglycans delivered in vivo inhibit pulmonary metastasis of tumor cells
    • Mizumoto S, Takahashi J, &, Sugahara K, (2012) Receptor for advanced glycation end products (RAGE) functions as a receptor for specific sulfated glycosaminoglycans, and anti-RAGE antibody or the sulfated glycosaminoglycans delivered in vivo inhibit pulmonary metastasis of tumor cells. J Biol Chem 287, 18985-18994.
    • (2012) J Biol Chem , vol.287 , pp. 18985-18994
    • Mizumoto, S.1    Takahashi, J.2    Sugahara, K.3
  • 19
    • 0345059766 scopus 로고    scopus 로고
    • Intravital imaging of cell movement in tumours
    • Condeelis J, &, Segall JE, (2003) Intravital imaging of cell movement in tumours. Nat Rev Cancer 3, 921-930. (Pubitemid 37500177)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.12 , pp. 921-930
    • Condeelis, J.1    Segall, J.E.2
  • 20
    • 0036488589 scopus 로고    scopus 로고
    • Role of integrins in cell invasion and migration
    • Hood JD, &, Cheresh DA, (2002) Role of integrins in cell invasion and migration. Nat Rev Cancer 2, 91-100. (Pubitemid 37328796)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.2 , pp. 91-100
    • Hood, J.D.1    Cheresh, D.A.2
  • 21
    • 58849106652 scopus 로고    scopus 로고
    • A tense situation: Forcing tumour progression
    • Butcher DT, Alliston T, &, Weaver VM, (2009) A tense situation: forcing tumour progression. Nat Rev Cancer 9, 108-122.
    • (2009) Nat Rev Cancer , vol.9 , pp. 108-122
    • Butcher, D.T.1    Alliston, T.2    Weaver, V.M.3
  • 23
    • 79959636906 scopus 로고    scopus 로고
    • The physics of cancer: The role of physical interactions and mechanical forces in metastasis
    • Wirtz D, Konstantopoulos K, &, Searson PC, (2011) The physics of cancer: the role of physical interactions and mechanical forces in metastasis. Nat Rev Cancer 11, 512-522.
    • (2011) Nat Rev Cancer , vol.11 , pp. 512-522
    • Wirtz, D.1    Konstantopoulos, K.2    Searson, P.C.3
  • 24
    • 34248594553 scopus 로고    scopus 로고
    • Metastasis: recent discoveries and novel treatment strategies
    • DOI 10.1016/S0140-6736(07)60781-8, PII S0140673607607818
    • Eccles SA, &, Welch DR, (2007) Metastasis: recent discoveries and novel treatment strategies. Lancet 369, 1742-1757. (Pubitemid 46755391)
    • (2007) Lancet , vol.369 , Issue.9574 , pp. 1742-1757
    • Eccles, S.A.1    Welch, D.R.2
  • 25
    • 0038481970 scopus 로고    scopus 로고
    • The pathogenesis of cancer metastasis: The 'seed and soil' hypothesis revisited
    • DOI 10.1038/nrc1098
    • Fidler IJ, (2003) The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat Rev Cancer 3, 453-458. (Pubitemid 37328849)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.6 , pp. 453-458
    • Fidler, I.J.1
  • 26
    • 33846149695 scopus 로고    scopus 로고
    • Chondroitin sulfate proteoglycans in tumor progression
    • Wegrowski Y, &, Maquart FX, (2006) Chondroitin sulfate proteoglycans in tumor progression. Adv Pharmacol 53, 297-321.
    • (2006) Adv Pharmacol , vol.53 , pp. 297-321
    • Wegrowski, Y.1    Maquart, F.X.2
  • 27
    • 0026592507 scopus 로고
    • A cell surface chondroitin sulfate proteoglycan, immunologically related to CD44, is involved in type i collagen-mediated melanoma cell motility and invasion
    • Faassen AE, Schrager JA, Klein DJ, Oegema TR, Couchman JR, &, McCarthy JB, (1992) A cell surface chondroitin sulfate proteoglycan, immunologically related to CD44, is involved in type I collagen-mediated melanoma cell motility and invasion. J Cell Biol 116, 521-531.
    • (1992) J Cell Biol , vol.116 , pp. 521-531
    • Faassen, A.E.1    Schrager, J.A.2    Klein, D.J.3    Oegema, T.R.4    Couchman, J.R.5    McCarthy, J.B.6
  • 29
    • 0029940271 scopus 로고    scopus 로고
    • Cell surface chondroitin sulfate proteoglycans in tumor cell adhesion, motility and invasion
    • DOI 10.1006/scbi.1996.0021
    • Iida J, Meijne AM, Knutson JR, Furcht LT, &, McCarthy JB, (1996) Cell surface chondroitin sulfate proteoglycans in tumor cell adhesion, motility and invasion. Semin Cancer Biol 7, 155-162. (Pubitemid 26179262)
    • (1996) Seminars in Cancer Biology , vol.7 , Issue.3 , pp. 155-162
    • Iida, J.1    Meijne, A.M.L.2    Knutson, J.R.3    Furcht, L.T.4    McCarthy, J.B.5
  • 30
    • 0023870372 scopus 로고
    • Immunohistochemical localization of chondroitin sulphate and dermatan sulphate proteoglycans in tumour tissues
    • Fukatsu T, Sobue M, Nagasaka T, Ohiwa N, Fukata S, Nakashima N, &, Takeuchi J, (1988) Immunohistochemical localization of chondroitin sulphate and dermatan sulphate proteoglycans in tumour tissues. Br J Cancer 57, 74-78. (Pubitemid 18067107)
    • (1988) British Journal of Cancer , vol.57 , Issue.1 , pp. 74-78
    • Fukatsu, T.1    Sobue, M.2    Nagasaka, T.3    Ohiwa, N.4    Fukata, S.5    Nakashima, N.6    Takeuchi, J.7
  • 31
    • 0024379745 scopus 로고
    • Neoplastic modulation of extracellular matrix: Stimulation of chondroitin sulfate proteoglycan and hyaluronic acid synthesis in co-cultures of human colon carcinoma and smooth muscle cells
    • DOI 10.1002/jcb.240390403
    • Iozzo RV, Sampson PM, &, Schmitt GK, (1989) Neoplastic modulation of extracellular matrix: stimulation of chondroitin sulfate proteoglycan and hyaluronic acid synthesis in co-cultures of human colon carcinoma and smooth muscle cells. J Cell Biochem 39, 355-378. (Pubitemid 19137347)
    • (1989) Journal of Cellular Biochemistry , vol.39 , Issue.4 , pp. 355-378
    • Iozzo, R.V.1    Sampson, P.M.2    Schmitt, G.K.3
  • 33
    • 0028018781 scopus 로고
    • Altered proteoglycan gene expression and the tumor stroma
    • Iozzo RV, &, Cohen I, (1994) Altered proteoglycan gene expression and the tumor stroma. EXS 70, 199-214.
    • (1994) EXS , vol.70 , pp. 199-214
    • Iozzo, R.V.1    Cohen, I.2
  • 36
    • 5444261094 scopus 로고    scopus 로고
    • The stroma reaction myofibroblast: A key player in the control of tumor cell behavior
    • DOI 10.1387/ijdb.041802ad, Invasion in Cancer and Embryonic Development
    • Desmoulière A, Guyot C, &, Gabbiani G, (2004) The stroma reaction myofibroblast: a key player in the control of tumor cell behavior. Int J Dev Biol 48, 509-517. (Pubitemid 39360401)
    • (2004) International Journal of Developmental Biology , vol.48 , Issue.5-6 , pp. 509-517
    • Desmouliere, A.1    Guyot, C.2    Gabbiani, G.3
  • 37
    • 0024474545 scopus 로고
    • The Engelberth-Holm-Swarm mouse tumor produces undersulfated heparan sulfate and oversulfated galactosaminoglycans
    • Sugahara K, Okumura Y, &, Yamashina I, (1989) The Engelbreth-Holm-Swarm mouse tumor produces undersulfated heparan sulfate and oversulfated galactosaminoglycans. Biochem Biophys Res Commun 162, 189-197. (Pubitemid 19185845)
    • (1989) Biochemical and Biophysical Research Communications , vol.162 , Issue.1 , pp. 189-197
    • Sugahara, K.1    Okumura, Y.2    Yamashina, I.3
  • 38
    • 34248396018 scopus 로고    scopus 로고
    • The utility of formalin-fixed and paraffin-embedded tissue blocks for quantitative analysis of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase mRNA expressed by colorectal cancer cells
    • DOI 10.1267/ahc.07004
    • Ito Y, Watanabe M, Nishizawa T, Omachi T, Kobayashi T, Kasama S, Habuchi O, &, Nakayama J, (2007) The utility of formalin-fixed and paraffin-embedded tissue blocks for quantitative analysis of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase mRNA expressed by colorectal cancer cells. Acta Histochem Cytochem 40, 53-59. (Pubitemid 46743502)
    • (2007) Acta Histochemica et Cytochemica , vol.40 , Issue.2 , pp. 53-59
    • Ito, Y.1    Watanabe, M.2    Nishizawa, T.3    Omachi, T.4    Kobayashi, T.5    Kasama, S.6    Habuchi, O.7    Nakayama, J.8
  • 39
    • 0037113896 scopus 로고    scopus 로고
    • Specific molecular interactions of oversulfated chondroitin sulfate E with various heparin-binding growth factors: Implications as a physiological binding partner in the brain and other tissues
    • DOI 10.1074/jbc.M207105200
    • Deepa SS, Umehara Y, Higashiyama S, Itoh N, &, Sugahara K, (2002) Specific interactions of oversulfated chondroitin sulfate E with various heparin-binding growth factors. Implications as a physiological binding partner. J Biol Chem 277, 43707-43716. (Pubitemid 36157787)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.46 , pp. 43707-43716
    • Deepa, S.S.1    Umehara, Y.2    Higashiyama, S.3    Itoh, N.4    Sugahara, K.5
  • 40
    • 0041355233 scopus 로고    scopus 로고
    • Hyaluronan oligosaccharides induce CD44 cleavage and promote cell migration in CD44-expressing tumor cells
    • DOI 10.1074/jbc.M300347200
    • Sugahara KN, Murai T, Nishinakamura H, Kawashima H, Saya H, &, Miyasaka M, (2003) Hyaluronan oligosaccharides induce CD44 cleavage and promote cell migration in CD44-expressing tumor cells. J Biol Chem 278, 32259-32265. (Pubitemid 37048419)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.34 , pp. 32259-32265
    • Sugahara, K.N.1    Murai, T.2    Nishinakamura, H.3    Kawashima, H.4    Saya, H.5    Miyasaka, M.6
  • 42
    • 84861880572 scopus 로고    scopus 로고
    • Strategies for the discovery and development of therapies for metastatic breast cancer
    • Eckhardt BL, Francis PA, Parker BS, &, Anderson RL, (2012) Strategies for the discovery and development of therapies for metastatic breast cancer. Nat Rev Drug Discov 11, 479-497.
    • (2012) Nat Rev Drug Discov , vol.11 , pp. 479-497
    • Eckhardt, B.L.1    Francis, P.A.2    Parker, B.S.3    Anderson, R.L.4
  • 43
    • 0033289060 scopus 로고    scopus 로고
    • Model for mediastinal lymph node metastasis produced by orthotopic intrapulmonary implantation of lung cancer cells in mice
    • Yamaura T, Doki Y, Murakami K, &, Saiki I, (1999) Model for mediastinal lymph node metastasis produced by orthotopic intrapulmonary implantation of lung cancer cells in mice. Hum Cell 12, 197-204.
    • (1999) Hum Cell , vol.12 , pp. 197-204
    • Yamaura, T.1    Doki, Y.2    Murakami, K.3    Saiki, I.4
  • 45
    • 0034531291 scopus 로고    scopus 로고
    • Inhibition of the midkine-mediated neural cell adhesion to culture substrates by chondroitin sulfate E. Specific molecular interactions of midkine with chondroitin sulfate e
    • Ueoka C, Kaneda N, Okazaki I, Nadanaka S, Muramatsu T, &, Sugahara K, (2000) Inhibition of the midkine-mediated neural cell adhesion to culture substrates by chondroitin sulfate E. Specific molecular interactions of midkine with chondroitin sulfate E. J Biol Chem 275, 37407-37413.
    • (2000) J Biol Chem , vol.275 , pp. 37407-37413
    • Ueoka, C.1    Kaneda, N.2    Okazaki, I.3    Nadanaka, S.4    Muramatsu, T.5    Sugahara, K.6
  • 46
    • 84874818623 scopus 로고    scopus 로고
    • Expression of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase involved in chondroitin sulfate synthesis is responsible for pulmonary metastasis
    • Mizumoto S, Watanabe M, Yamada S, &, Sugahara K, (2013) Expression of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase involved in chondroitin sulfate synthesis is responsible for pulmonary metastasis. Bio Med Res Int 2013, 656319.
    • (2013) Bio Med Res Int , vol.2013 , pp. 656319
    • Mizumoto, S.1    Watanabe, M.2    Yamada, S.3    Sugahara, K.4
  • 47
    • 0037066693 scopus 로고    scopus 로고
    • Oversulfated chondroitin/dermatan sulfates containing GlcAβ1/IdoAα1-3GalNAc(4,6-O-disulfate) interact with L- and P-selectin and chemokines
    • DOI 10.1074/jbc.M200396200
    • Kawashima H, Atarashi K, Hirose M, Hirose J, Yamada S, Sugahara K, &, Miyasaka M, (2002) Oversulfated chondroitin/dermatan sulfates containing GlcAβ1/IdoAα1-3GalNAc(4,6-O-disulfate) interact with L- and P-selectin and chemokines. J Biol Chem 277, 12921-12930. (Pubitemid 34952659)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.15 , pp. 12921-12930
    • Kawashima, H.1    Atarashi, K.2    Hirose, M.3    Hirose, J.4    Yamada, S.5    Sugahara, K.6    Miyasaka, M.7
  • 52
    • 77951922772 scopus 로고    scopus 로고
    • The receptor for advanced glycation end products (RAGE) and the lung
    • Buckley ST, &, Ehrhardt C, (2010) The receptor for advanced glycation end products (RAGE) and the lung. J Biomed Biotechnol 2010, 917108.
    • (2010) J Biomed Biotechnol , vol.2010 , pp. 917108
    • Buckley, S.T.1    Ehrhardt, C.2
  • 53
    • 82355181520 scopus 로고    scopus 로고
    • Heparan sulfate is essential for high mobility group protein 1 (HMGB1) signaling by the receptor for advanced glycation end products (RAGE)
    • Xu D, Young J, Song D, &, Esko JD, (2011) Heparan sulfate is essential for high mobility group protein 1 (HMGB1) signaling by the receptor for advanced glycation end products (RAGE). J Biol Chem 286, 41736-41744.
    • (2011) J Biol Chem , vol.286 , pp. 41736-41744
    • Xu, D.1    Young, J.2    Song, D.3    Esko, J.D.4
  • 56
    • 78650341420 scopus 로고    scopus 로고
    • The 1.5 Å crystal structure of human receptor for advanced glycation endproducts (RAGE) ectodomains reveals unique features determining ligand binding
    • Park H, Adsit FG, &, Boyington JC, (2010) The 1.5 Å crystal structure of human receptor for advanced glycation endproducts (RAGE) ectodomains reveals unique features determining ligand binding. J Biol Chem 285, 40762-40770.
    • (2010) J Biol Chem , vol.285 , pp. 40762-40770
    • Park, H.1    Adsit, F.G.2    Boyington, J.C.3
  • 57
    • 34547116890 scopus 로고    scopus 로고
    • Functions of chondroitin sulfate/dermatan sulfate chains in brain development: Critical roles of E and iE disaccharide units recognized by a single chain antibody GD3G7
    • DOI 10.1074/jbc.M700630200
    • Purushothaman A, Fukuda J, Mizumoto S, ten Dam GB, van Kuppevelt TH, Kitagawa H, Mikami T, &, Sugahara K, (2007) Functions of chondroitin sulfate/dermatan sulfate chains in brain development. Critical roles of E and iE disaccharide units recognized by a single chain antibody GD3G7. J Biol Chem 282, 19442-19452. (Pubitemid 47100083)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.27 , pp. 19442-19452
    • Purushothaman, A.1    Fukuda, J.2    Mizumoto, S.3    Ten Dam, G.B.4    Van Kuppevelt, T.H.5    Kitagawa, H.6    Mikami, T.7    Sugahara, K.8
  • 58
    • 33847666790 scopus 로고    scopus 로고
    • Novel sulfated octa- and decasaccharides from squid cartilage chondroitin sulfate E: Sequencing and application for determination of the epitope structure of the monoclonal antibody MO-225
    • DOI 10.1021/bi602374m
    • Deepa SS, Kalayanamitra K, Ito Y, Kongtawelert P, Fukui S, Yamada S, Mikami T, &, Sugahara K, (2007) Novel sulfated octa- and decasaccharides from squid cartilage chondroitin sulfate E: sequencing and application for determination of the epitope structure of the monoclonal antibody MO-225. Biochemistry 46, 2453-2465. (Pubitemid 46362419)
    • (2007) Biochemistry , vol.46 , Issue.9 , pp. 2453-2465
    • Deepa, S.S.1    Kalayanamitra, K.2    Ito, Y.3    Kongtawelert, P.4    Fukui, S.5    Yamada, S.6    Mikami, T.7    Sugahara, K.8
  • 60
    • 77956641177 scopus 로고    scopus 로고
    • Proteoglycans in health and disease: Novel roles for proteoglycans in malignancy and their pharmacological targeting
    • Theocharis AD, Skandalis SS, Tzanakakis GN, &, Karamanos NK, (2010) Proteoglycans in health and disease: novel roles for proteoglycans in malignancy and their pharmacological targeting. FEBS J 277, 3904-3923.
    • (2010) FEBS J , vol.277 , pp. 3904-3923
    • Theocharis, A.D.1    Skandalis, S.S.2    Tzanakakis, G.N.3    Karamanos, N.K.4
  • 62
    • 84859102378 scopus 로고    scopus 로고
    • Glycosaminoglycans: From 'cellular glue' to novel therapeutical agents
    • Karamanos NK, &, Tzanakakis GN, (2012) Glycosaminoglycans: from 'cellular glue' to novel therapeutical agents. Curr Opin Pharmacol 12, 220-222.
    • (2012) Curr Opin Pharmacol , vol.12 , pp. 220-222
    • Karamanos, N.K.1    Tzanakakis, G.N.2
  • 63
    • 0036320685 scopus 로고    scopus 로고
    • N-glycans on the receptor for advanced glycation end products influence amphoterin binding and neurite outgrowth
    • DOI 10.1046/j.0022-3042.2002.00796.x
    • Srikrishna G, Huttunen HJ, Johansson L, Weigle B, Yamaguchi Y, Rauvala H, &, Freeze HH, (2002) N-Glycans on the receptor for advanced glycation end products influence amphoterin binding and neurite outgrowth. J Neurochem 80, 998-1008. (Pubitemid 34809952)
    • (2002) Journal of Neurochemistry , vol.80 , Issue.6 , pp. 998-1008
    • Srikrishna, G.1    Huttunen, H.J.2    Johansson, L.3    Weigle, B.4    Yamaguchi, Y.5    Rauvala, H.6    Freeze, H.H.7


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