Proliferative effect of histamine on MA-10 leydig tumor cells mediated through HRH2 activation, transient elevation in cAMP production, and increased extracellular signal-regulated kinase phosphorylation levels

Biology of Reproduction

Volumn 87, Issue 6, 2012, Pages

  Pagotto, Romina María ^a   Monzón, Casandra ^a   Moreno, Marcos Besio ^a   Pignataro, Omar Pedro ^a,b   Mondillo, Carolina ^b  

^a National Research Council ^*  (Argentina)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Cyclic adenosine monophosphate (cAMP); Histamine; Reproductive immunology; Signal transduction; Testis

Indexed keywords

CYCLIC AMP; HISTAMINE; HISTAMINE H2 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; ENZYME INHIBITOR; HISTAMINE AGONIST; HISTIDINE DECARBOXYLASE; TUMOR PROTEIN;

ANDROGEN SYNTHESIS; ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; AUTOCRINE EFFECT; CANCER CELL CULTURE; CELL COUNT; CELL LYSATE; CELL PROLIFERATION; CONTROLLED STUDY; GERM CELL; IMMUNODETECTION; INHIBITION KINETICS; LEYDIG CELL; LEYDIG CELL TUMOR; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; STIMULATION; TESTIS; TESTIS FUNCTION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CHEMISTRY; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; MALE; METABOLISM; PHOSPHORYLATION; PROTEIN PROCESSING; RAT; SECOND MESSENGER; SPRAGUE DAWLEY RAT; STEM CELL; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; CELLS, CULTURED; CYCLIC AMP; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HISTAMINE; HISTAMINE AGONISTS; HISTIDINE DECARBOXYLASE; LEYDIG CELL TUMOR; LEYDIG CELLS; MALE; MICE; NEOPLASM PROTEINS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, HISTAMINE H2; SECOND MESSENGER SYSTEMS; STEM CELLS;

EID: 84877664092     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.112.102905     Document Type: Article

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