메뉴 건너뛰기




Volumn 14, Issue 7, 2013, Pages 735-744

Assessment of a pharmacogenomic marker panel in a polypharmacy population identified from electronic medical records

Author keywords

ADME; biorepository; BioVU; CYP2D6; genotyping; Illumina; medicine rare variants; personalized medicine; precision

Indexed keywords

CLOPIDOGREL; CODEINE; CYCLOSPORIN; CYTOCHROME P450 2D6; HEPARIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOSUPPRESSIVE AGENT; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NEUROLEPTIC AGENT; RAPAMYCIN; SEROTONIN UPTAKE INHIBITOR; TACROLIMUS; TAMOXIFEN; WARFARIN;

EID: 84877655072     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/pgs.13.64     Document Type: Article
Times cited : (23)

References (33)
  • 1
    • 34248589343 scopus 로고    scopus 로고
    • Identifying the genotype behind the phenotype: A role model found in VKORC1 and its association with warfarin dosing
    • Crawford DC, Ritchie MD, Rieder MJ. Identifying the genotype behind the phenotype: a role model found in VKORC1 and its association with warfarin dosing. Pharmacogenomics 8(5), 487-496 (2007).
    • (2007) Pharmacogenomics , vol.8 , Issue.5 , pp. 487-496
    • Crawford, D.C.1    Ritchie, M.D.2    Rieder, M.J.3
  • 2
    • 84859889705 scopus 로고    scopus 로고
    • Genetic determinants of response to cardiovascular drugs
    • Wells QS, Delaney JT, Roden DM. Genetic determinants of response to cardiovascular drugs. Curr. Opin. Cardiol. 27(3), 253-261 (2012).
    • (2012) Curr. Opin. Cardiol. , vol.27 , Issue.3 , pp. 253-261
    • Wells, Q.S.1    Delaney, J.T.2    Roden, D.M.3
  • 3
    • 84862620703 scopus 로고    scopus 로고
    • Operational implementation of prospective genotyping for personalized medicine: The design of the vanderbilt PREDICT project
    • Pulley JM, Denny JC, Peterson JF, et al. Operational implementation of prospective genotyping for personalized medicine: the design of the vanderbilt PREDICT project. Clin. Pharmacol. Ther. 92(1), 87-95 (2012).
    • (2012) Clin. Pharmacol. Ther. , vol.92 , Issue.1 , pp. 87-95
    • Pulley, J.M.1    Denny, J.C.2    Peterson, J.F.3
  • 4
    • 61549096893 scopus 로고    scopus 로고
    • Ability of whole-genome SNP arrays to capture 'must have' pharmacogenomic variants
    • Peters EJ, McLeod HL. Ability of whole-genome SNP arrays to capture 'must have' pharmacogenomic variants. Pharmacogenomics 9(11), 1573-1577 (2008).
    • (2008) Pharmacogenomics , vol.9 , Issue.11 , pp. 1573-1577
    • Peters, E.J.1    McLeod, H.L.2
  • 5
    • 79651470986 scopus 로고    scopus 로고
    • Pharmacogenomic biomarkers: New tools in current and future drug therapy
    • Sim SC, Ingelman-Sundberg M. Pharmacogenomic biomarkers: new tools in current and future drug therapy. Trends Pharmacol. Sci. 32(2), 72-81 (2011).
    • (2011) Trends Pharmacol. Sci. , vol.32 , Issue.2 , pp. 72-81
    • Sim, S.C.1    Ingelman-Sundberg, M.2
  • 6
    • 0842312531 scopus 로고    scopus 로고
    • Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants
    • Nelson DR, Zeldin DC, Hoffman SM, Maltais LJ, Wain HM, Nebert DW. Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. Pharmacogenetics 14(1), 1-18 (2004).
    • (2004) Pharmacogenetics , vol.14 , Issue.1 , pp. 1-18
    • Nelson, D.R.1    Zeldin, D.C.2    Hoffman, S.M.3    Maltais, L.J.4    Wain, H.M.5    Nebert, D.W.6
  • 7
    • 33947603700 scopus 로고    scopus 로고
    • Comprehensive assessment of metabolic enzyme and transporter genes using the affymetrix targeted genotyping system
    • Dumaual C, Miao X, Daly TM, et al. Comprehensive assessment of metabolic enzyme and transporter genes using the affymetrix targeted genotyping system. Pharmacogenomics 8(3), 293-305 (2007).
    • (2007) Pharmacogenomics , vol.8 , Issue.3 , pp. 293-305
    • Dumaual, C.1    Miao, X.2    Daly, T.M.3
  • 8
    • 83655184675 scopus 로고    scopus 로고
    • The use of a DNA biobank linked to electronic medical records to characterize pharmacogenomic predictors of tacrolimus dose requirement in kidney transplant recipients
    • Birdwell KA, Grady B, Choi L, et al. The use of a DNA biobank linked to electronic medical records to characterize pharmacogenomic predictors of tacrolimus dose requirement in kidney transplant recipients. Pharmacogenet. Genomics 22(1), 32-42 (2012).
    • (2012) Pharmacogenet. Genomics , vol.22 , Issue.1 , pp. 32-42
    • Birdwell, K.A.1    Grady, B.2    Choi, L.3
  • 9
    • 58749094444 scopus 로고    scopus 로고
    • Cytochrome p-450 polymorphisms and response to clopidogrel
    • Mega JL, Close SL, Wiviott SD, et al. Cytochrome p-450 polymorphisms and response to clopidogrel. N. Engl. J. Med. 360(4), 354-362 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , Issue.4 , pp. 354-362
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3
  • 10
    • 49949093313 scopus 로고    scopus 로고
    • Development of a large-scale de-identified DNA biobank to enable personalized medicine
    • Roden DM, Pulley JM, Basford MA, et al. Development of a large-scale de-identified DNA biobank to enable personalized medicine. Clin. Pharmacol. Ther. 84(3), 362-369 (2008).
    • (2008) Clin. Pharmacol. Ther. , vol.84 , Issue.3 , pp. 362-369
    • Roden, D.M.1    Pulley, J.M.2    Basford, M.A.3
  • 11
    • 77958553386 scopus 로고    scopus 로고
    • Assessing the accuracy of observer-reported ancestry in a biorepository linked to electronic medical records
    • Dumitrescu L, Ritchie MD, Brown-Gentry K, et al. Assessing the accuracy of observer-reported ancestry in a biorepository linked to electronic medical records. Genet. Med. 12(10), 648-650 (2010).
    • (2010) Genet. Med. , vol.12 , Issue.10 , pp. 648-650
    • Dumitrescu, L.1    Ritchie, M.D.2    Brown-Gentry, K.3
  • 13
    • 33847641458 scopus 로고    scopus 로고
    • The pharmacogenetics research network: From SNP discovery to clinical drug response
    • Giacomini KM, Brett CM, Altman RB, et al. The pharmacogenetics research network: from SNP discovery to clinical drug response. Clin. Pharmacol. Ther. 81(3), 328-345 (2007).
    • (2007) Clin. Pharmacol. Ther. , vol.81 , Issue.3 , pp. 328-345
    • Giacomini, K.M.1    Brett, C.M.2    Altman, R.B.3
  • 14
    • 67249117049 scopus 로고    scopus 로고
    • Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
    • Hindorff LA, Sethupathy P, Junkins HA, et al. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc. Natl Acad. Sci. USA 106(23), 9362-9367 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , Issue.23 , pp. 9362-9367
    • Hindorff, L.A.1    Sethupathy, P.2    Junkins, H.A.3
  • 15
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analyses
    • Purcell S, Neale B, Todd-Brown K, et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81(3), 559-575 (2007).
    • (2007) Am. J. Hum. Genet. , vol.81 , Issue.3 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3
  • 17
    • 33644876453 scopus 로고    scopus 로고
    • SNP500Cancer: A public resource for sequence validation, assay development, and frequency analysis for genetic variation in candidate genes
    • Packer BR, Yeager M, Burdett L, et al. SNP500Cancer: a public resource for sequence validation, assay development, and frequency analysis for genetic variation in candidate genes. Nucleic Acids Res. 34, D617-D621 (2006).
    • (2006) Nucleic Acids Res , vol.34
    • Packer, B.R.1    Yeager, M.2    Burdett, L.3
  • 18
    • 79959503826 scopus 로고    scopus 로고
    • The international hapmap project
    • International Hapmap Consortium
    • International HapMap Consortium. The International HapMap Project. Nature 426(6968), 789-796 (2003).
    • (2003) Nature , vol.426 , Issue.6968 , pp. 789-796
  • 19
    • 0036088113 scopus 로고    scopus 로고
    • PharmGKB: The pharmacogenetics knowledge base
    • Hewett M, Oliver DE, Rubin DL, et al. PharmGKB: the pharmacogenetics knowledge base. Nucleic Acids Res. 30(1), 163-165 (2002).
    • (2002) Nucleic Acids Res , vol.30 , Issue.1 , pp. 163-165
    • Hewett, M.1    Oliver, D.E.2    Rubin, D.L.3
  • 20
    • 44649121538 scopus 로고    scopus 로고
    • The environmental genome project: Reference polymorphisms for drug metabolism genes and genome-wide association studies
    • Rieder MJ, Livingston RJ, Stanaway IB, Nickerson DA. The environmental genome project: reference polymorphisms for drug metabolism genes and genome-wide association studies. Drug Metab. Rev. 40(2), 241-261 (2008).
    • (2008) Drug Metab. Rev. , vol.40 , Issue.2 , pp. 241-261
    • Rieder, M.J.1    Livingston, R.J.2    Stanaway, I.B.3    Nickerson, D.A.4
  • 21
    • 0035173378 scopus 로고    scopus 로고
    • DbSNP: The NCBI database of genetic variation
    • Sherry ST, Ward MH, Kholodov M, et al. dbSNP: the NCBI database of genetic variation. Nucleic Acids Res. 29(1), 308-311 (2001).
    • (2001) Nucleic Acids Res , vol.29 , Issue.1 , pp. 308-311
    • Sherry, S.T.1    Ward, M.H.2    Kholodov, M.3
  • 22
    • 33847062078 scopus 로고    scopus 로고
    • Genotyping and haplotyping of CYP2C19 functional alleles on thin-film biosensor chips
    • Nakamoto K, Kidd JR, Jenison RD, et al. Genotyping and haplotyping of CYP2C19 functional alleles on thin-film biosensor chips. Pharmacogenet. Genomics 17(2), 103-114 (2007).
    • (2007) Pharmacogenet. Genomics , vol.17 , Issue.2 , pp. 103-114
    • Nakamoto, K.1    Kidd, J.R.2    Jenison, R.D.3
  • 23
    • 34748848639 scopus 로고    scopus 로고
    • The NCBI dbGaP database of genotypes and phenotypes
    • Mailman MD, Feolo M, Jin Y, et al. The NCBI dbGaP database of genotypes and phenotypes. Nat. Genet. 39(10), 1181-1186 (2007).
    • (2007) Nat. Genet. , vol.39 , Issue.10 , pp. 1181-1186
    • Mailman, M.D.1    Feolo, M.2    Jin, Y.3
  • 24
    • 73549120609 scopus 로고    scopus 로고
    • Clinical pharmacology and pharmacogenetics in a genomics era: The DMET platform
    • Sissung TM, English BC, Venzon D, Figg WD, Deeken JF. Clinical pharmacology and pharmacogenetics in a genomics era: the DMET platform. Pharmacogenomics 11(1), 89-103 (2010).
    • (2010) Pharmacogenomics , vol.11 , Issue.1 , pp. 89-103
    • Sissung, T.M.1    English, B.C.2    Venzon, D.3    Figg, W.D.4    Deeken, J.F.5
  • 25
    • 84855968708 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype
    • Crews KR, Gaedigk A, Dunnenberger HM, et al. Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype. Clin. Pharmacol. Ther. 91(2), 321-326 (2012).
    • (2012) Clin. Pharmacol. Ther. , vol.91 , Issue.2 , pp. 321-326
    • Crews, K.R.1    Gaedigk, A.2    Dunnenberger, H.M.3
  • 26
    • 80052962391 scopus 로고    scopus 로고
    • Clinical pharmacogenetics implementation consortium guidelines for CYP2C9 and VKORC1 genotypes and warfarin dosing
    • Johnson JA, Gong L, Whirl-Carrillo M, et al. Clinical pharmacogenetics implementation consortium guidelines for CYP2C9 and VKORC1 genotypes and warfarin dosing. Clin. Pharmacol. Ther. 90(4), 625-629 (2011).
    • (2011) Clin. Pharmacol. Ther. , vol.90 , Issue.4 , pp. 625-629
    • Johnson, J.A.1    Gong, L.2    Whirl-Carrillo, M.3
  • 27
    • 84875438476 scopus 로고    scopus 로고
    • Clinical pharmacogenetics implementation consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing: 2013 update
    • Relling MV, Gardner EE, Sandborn WJ, et al. Clinical pharmacogenetics implementation consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing: 2013 update. Clin. Pharmacol. Ther. 93(4), 324-325 (2013).
    • (2013) Clin. Pharmacol. Ther. , vol.93 , Issue.4 , pp. 324-325
    • Relling, M.V.1    Gardner, E.E.2    Sandborn, W.J.3
  • 28
    • 79960613122 scopus 로고    scopus 로고
    • Clinical pharmacogenetics implementation consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy
    • Scott SA, Sangkuhl K, Gardner EE, et al. Clinical pharmacogenetics implementation consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy. Clin. Pharmacol. Ther. 90(2), 328-332 (2011).
    • (2011) Clin. Pharmacol. Ther. , vol.90 , Issue.2 , pp. 328-332
    • Scott, S.A.1    Sangkuhl, K.2    Gardner, E.E.3
  • 29
    • 84862600938 scopus 로고    scopus 로고
    • The clinical pharmacogenomics implementation consortium: CPIC guideline for SLCO1B1 and simvastatin-induced myopathy
    • Wilke R A, Ramsey LB, Johnson SG, et al. The clinical pharmacogenomics implementation consortium: CPIC guideline for SLCO1B1 and simvastatin-induced myopathy. Clin. Pharmacol. Ther. 92(1), 112-117 (2012).
    • (2012) Clin. Pharmacol. Ther. , vol.92 , Issue.1 , pp. 112-117
    • Wilke, R.A.1    Ramsey, L.B.2    Johnson, S.G.3
  • 31
    • 13544249943 scopus 로고    scopus 로고
    • Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6) : clinical consequences, evolutionary aspects and functional diversity
    • Ingelman-Sundberg M. Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6) : clinical consequences, evolutionary aspects and functional diversity. Pharmacogenomics J. 5(1), 6-13 (2005).
    • (2005) Pharmacogenomics J , vol.5 , Issue.1 , pp. 6-13
    • Ingelman-Sundberg, M.1
  • 32
    • 77951553451 scopus 로고    scopus 로고
    • Drug-induced liver injury: Past, present and future
    • Daly AK. Drug-induced liver injury: past, present and future. Pharmacogenomics 11(5), 607-611 (2010).
    • (2010) Pharmacogenomics , vol.11 , Issue.5 , pp. 607-611
    • Daly, A.K.1
  • 33
    • 84877681528 scopus 로고    scopus 로고
    • Illumina
    • Illumina. www.illumina.com


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.