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Volumn 14, Issue 8, 2013, Pages 1017-1028

An update on the pharmacotherapy of neovascular age-related macular degeneration

Author keywords

Aflibercept; Age related macular degeneration; Anti angiogenic therapy; Bevacizumab; Choroidal neovascularization; Intravitreal injection; Pegaptanib sodium; Ranibizumab; VEGF; Verteporfin

Indexed keywords

AFLIBERCEPT; BEVACIZUMAB; CYTOKINE RECEPTOR ANTAGONIST; DEXAMETHASONE; FOVISTA; LAMPALIZUMAB; PEGAPTANIB; PLATELET DERIVED GROWTH FACTOR ANTAGONIST; RANIBIZUMAB; SQUALAMINE; TRIAMCINOLONE ACETONIDE; UNCLASSIFIED DRUG; VERTEPORFIN;

EID: 84877651573     PISSN: 14656566     EISSN: 17447666     Source Type: Journal    
DOI: 10.1517/14656566.2013.787410     Document Type: Review
Times cited : (38)

References (91)
  • 1
    • 0028934221 scopus 로고
    • An international classification and grading system for age-related maculopathy and age-related macular degeneration
    • The International ARM Epidemiological Study Group
    • Bird AC, Bressler NM, Bressler SB, et al. An international classification and grading system for age-related maculopathy and age-related macular degeneration. The International ARM Epidemiological Study Group. Surv Ophthalmol 1995;39(5):367-74
    • (1995) Surv Ophthalmol , vol.39 , Issue.5 , pp. 367-374
    • Bird, A.C.1    Bressler, N.M.2    Bressler, S.B.3
  • 2
    • 0028772508 scopus 로고
    • Diseases of the retina
    • D'Amico DJ. Diseases of the retina. N Engl J Med 1994;331(2):95-106
    • (1994) N Engl J Med , vol.331 , Issue.2 , pp. 95-106
    • D'Amico, D.J.1
  • 4
    • 1842530296 scopus 로고    scopus 로고
    • Causes and prevalence of visual impairment among adults in the United States
    • Congdon N, O'Colmain B, Klaver CC, et al. Causes and prevalence of visual impairment among adults in the United States. Arch Ophthalmol 2004;122(4):477-85
    • (2004) Arch Ophthalmol , vol.122 , Issue.4 , pp. 477-485
    • Congdon, N.1    O'Colmain, B.2    Klaver, C.C.3
  • 5
    • 0028843796 scopus 로고
    • Prevalence of age-related maculopathy in Australia. The Blue Mountains Eye Study
    • Mitchell P, Smith W, Attebo K, Wang JJ. Prevalence of age-related maculopathy in Australia. The Blue Mountains Eye Study. Ophthalmology 1995;102(10):1450-60
    • (1995) Ophthalmology , vol.102 , Issue.10 , pp. 1450-1460
    • Mitchell, P.1    Smith, W.2    Attebo, K.3    Wang, J.J.4
  • 6
    • 0028839002 scopus 로고
    • The prevalence of age-related maculopathy in the Rotterdam Study
    • Vingerling JR, Dielemans I, Hofman A, et al. The prevalence of age-related maculopathy in the Rotterdam Study. Ophthalmology 1995;102(2):205-10
    • (1995) Ophthalmology , vol.102 , Issue.2 , pp. 205-210
    • Vingerling, J.R.1    Dielemans, I.2    Hofman, A.3
  • 7
    • 0034800655 scopus 로고    scopus 로고
    • A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS
    • Age-Related Eye Disease Study Research Group report no. 8
    • Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol 2001;119(10):1417-36
    • (2001) Arch Ophthalmol , vol.119 , Issue.10 , pp. 1417-1436
  • 8
    • 34548650913 scopus 로고    scopus 로고
    • The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS
    • report no. 22
    • SanGiovanni JP, Chew EY, Clemons TE, et al. The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS report no. 22. Arch Ophthalmol 2007;125(9):1225-32
    • (2007) Arch Ophthalmol , vol.125 , Issue.9 , pp. 1225-1232
    • SanGiovanni, J.P.1    Chew, E.Y.2    Clemons, T.E.3
  • 9
    • 79960342630 scopus 로고    scopus 로고
    • Update on geographic atrophy in age-related macular degeneration
    • Biarnes M, Mones J, Alonso J, Arias L. Update on geographic atrophy in age-related macular degeneration. Optom Vis Sci 2011;88(7):881-9
    • (2011) Optom Vis Sci , vol.88 , Issue.7 , pp. 881-889
    • Biarnes, M.1    Mones, J.2    Alonso, J.3    Arias, L.4
  • 10
  • 11
    • 0037398304 scopus 로고    scopus 로고
    • Intraocular concentration and pharmacokinetics of triamcinolone acetonide after a single intravitreal injection
    • Beer PM, Bakri SJ, Singh RJ, et al. Intraocular concentration and pharmacokinetics of triamcinolone acetonide after a single intravitreal injection. Ophthalmology 2003;110(4):681-6
    • (2003) Ophthalmology , vol.110 , Issue.4 , pp. 681-686
    • Beer, P.M.1    Bakri, S.J.2    Singh, R.J.3
  • 12
    • 0026515817 scopus 로고
    • Evaluation of the retinal toxicity and pharmacokinetics of dexamethasone after intravitreal injection
    • Kwak HW, D'Amico DJ. Evaluation of the retinal toxicity and pharmacokinetics of dexamethasone after intravitreal injection. Arch Ophthalmol 1992;110(2):259-66
    • (1992) Arch Ophthalmol , vol.110 , Issue.2 , pp. 259-266
    • Kwak, H.W.1    D'Amico, D.J.2
  • 13
    • 36749070458 scopus 로고    scopus 로고
    • Prospective, randomized clinical trial of intravitreal triamcinolone treatment of neovascular age-related macular degeneration: One-year results
    • Lee J, Freeman WR, Azen SP, et al. Prospective, randomized clinical trial of intravitreal triamcinolone treatment of neovascular age-related macular degeneration: One-year results. Retina 2007;27(9):1205-13
    • (2007) Retina , vol.27 , Issue.9 , pp. 1205-1213
    • Lee, J.1    Freeman, W.R.2    Azen, S.P.3
  • 14
    • 76549221861 scopus 로고
    • Subconjunctival injection of cortisone in iritis
    • Koff R, Rome S, Kasper R, et al. Subconjunctival injection of cortisone in iritis. J Am Med Assoc 1950;144(15):1259-60
    • (1950) J Am Med Assoc , vol.144 , Issue.15 , pp. 1259-1260
    • Koff, R.1    Rome, S.2    Kasper, R.3
  • 15
    • 34548677180 scopus 로고
    • Use of cortisone in severe bilateral uveitis
    • Theodore FH. Use of cortisone in severe bilateral uveitis. Eye Ear Nose Throat Mon 1950;29(6):314-15
    • (1950) Eye Ear Nose Throat Mon , vol.29 , Issue.6 , pp. 314-315
    • Theodore, F.H.1
  • 16
    • 34250798455 scopus 로고    scopus 로고
    • Safety profile of intravitreal triamcinolone acetonide
    • Baath J, Ells AL, Crichton A, et al. Safety profile of intravitreal triamcinolone acetonide. J Ocul Pharmacol Ther 2007;23(3):304-10
    • (2007) J Ocul Pharmacol Ther , vol.23 , Issue.3 , pp. 304-310
    • Baath, J.1    Ells, A.L.2    Crichton, A.3
  • 17
    • 84856601799 scopus 로고    scopus 로고
    • Further characterization of ocular safety profile of commercially available preserved and preservative-free triamcinolone acetonide
    • Li Y, Chen H, Hou J, et al. Further characterization of ocular safety profile of commercially available preserved and preservative-free triamcinolone acetonide. Retina 2012;32(2):364-74
    • (2012) Retina , vol.32 , Issue.2 , pp. 364-374
    • Li, Y.1    Chen, H.2    Hou, J.3
  • 18
    • 79953299899 scopus 로고    scopus 로고
    • Expanded 2-year follow-up of ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema
    • Elman MJ, Bressler NM, Qin H, et al. Expanded 2-year follow-up of ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. Ophthalmology 2011;118(4):609-14
    • (2011) Ophthalmology , vol.118 , Issue.4 , pp. 609-614
    • Elman, M.J.1    Bressler, N.M.2    Qin, H.3
  • 19
    • 79955053069 scopus 로고    scopus 로고
    • Visual outcome after intravitreal triamcinolone acetonide depends on optical coherence tomographic patterns in patients with diffuse diabetic macular edema
    • Shimura M, Yasuda K, Nakazawa T, et al. Visual outcome after intravitreal triamcinolone acetonide depends on optical coherence tomographic patterns in patients with diffuse diabetic macular edema. Retina 2011;31(4):748-54
    • (2011) Retina , vol.31 , Issue.4 , pp. 748-754
    • Shimura, M.1    Yasuda, K.2    Nakazawa, T.3
  • 20
    • 70349243148 scopus 로고    scopus 로고
    • A randomized trial comparing the efficacy and safety of intravitreal triamcinolone with observation to treat vision loss associated with macular edema secondary to central retinal vein occlusion: The Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) study report 5
    • Ip MS, Scott IU, VanVeldhuisen PC, et al. A randomized trial comparing the efficacy and safety of intravitreal triamcinolone with observation to treat vision loss associated with macular edema secondary to central retinal vein occlusion: The Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) study report 5. Arch Ophthalmol 2009;127(9):1101-14
    • (2009) Arch Ophthalmol , vol.127 , Issue.9 , pp. 1101-1114
    • Ip, M.S.1    Scott, I.U.2    VanVeldhuisen, P.C.3
  • 21
    • 84866352102 scopus 로고    scopus 로고
    • Three intravitreal bevacizumab versus two intravitreal triamcinolone injections in recent-onset branch retinal vein occlusion
    • Ramezani A, Esfandiari H, Entezari M, et al. Three intravitreal bevacizumab versus two intravitreal triamcinolone injections in recent-onset branch retinal vein occlusion. Graefes Arch Clin Exp Ophthalmol 2012;250(8):1149-60
    • (2012) Graefes Arch Clin Exp Ophthalmol , vol.250 , Issue.8 , pp. 1149-1160
    • Ramezani, A.1    Esfandiari, H.2    Entezari, M.3
  • 22
    • 70349247768 scopus 로고    scopus 로고
    • A randomized trial comparing the efficacy and safety of intravitreal triamcinolone with standard care to treat vision loss associated with macular Edema secondary to branch retinal vein occlusion: The Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) study report 6
    • Scott IU, Ip MS, VanVeldhuisen PC, et al. A randomized trial comparing the efficacy and safety of intravitreal triamcinolone with standard care to treat vision loss associated with macular Edema secondary to branch retinal vein occlusion: The Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) study report 6. Arch Ophthalmol 2009;127(9):1115-28
    • (2009) Arch Ophthalmol , vol.127 , Issue.9 , pp. 1115-1128
    • Scott, I.U.1    Ip, M.S.2    VanVeldhuisen, P.C.3
  • 23
    • 70349504173 scopus 로고    scopus 로고
    • The use of intraocular corticosteroids
    • Kiernan DF, Mieler WF. The use of intraocular corticosteroids. Expert Opin Pharmacother 2009;10(15):2511-25
    • (2009) Expert Opin Pharmacother , vol.10 , Issue.15 , pp. 2511-2525
    • Kiernan, D.F.1    Mieler, W.F.2
  • 24
    • 84864058031 scopus 로고    scopus 로고
    • Intraocular corticosteroids for posterior segment disease: 2012 update
    • Kiernan DF, Mieler WF. Intraocular corticosteroids for posterior segment disease: 2012 update. Expert Opin Pharmacother 2012;13(12):1679-94
    • (2012) Expert Opin Pharmacother , vol.13 , Issue.12 , pp. 1679-1694
    • Kiernan, D.F.1    Mieler, W.F.2
  • 25
    • 0028388759 scopus 로고
    • Photophysical and photosensitizing properties of benzoporphyrin derivative monoacid ring a bpd-ma
    • Aveline B, Hasan T, Redmond RW. Photophysical and photosensitizing properties of benzoporphyrin derivative monoacid ring A (BPD-MA). Photochem Photobiol 1994;59(3):328-35
    • (1994) Photochem Photobiol , vol.59 , Issue.3 , pp. 328-335
    • Aveline, B.1    Hasan, T.2    Redmond, R.W.3
  • 26
    • 0347126955 scopus 로고    scopus 로고
    • Verteporfin ocular photodynamic therapy
    • Bakri SJ, Kaiser PK. Verteporfin ocular photodynamic therapy. Expert Opin Pharmacother 2004;5(1):195-203
    • (2004) Expert Opin Pharmacother , vol.5 , Issue.1 , pp. 195-203
    • Bakri, S.J.1    Kaiser, P.K.2
  • 27
    • 0342632445 scopus 로고    scopus 로고
    • Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: One-year results of 2 randomized clinical trials-TAP report
    • Treatment of age-related macular degeneration with photodynamic therapy (TAP) Study Group
    • Treatment of age-related macular degeneration with photodynamic therapy (TAP) Study Group. Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: One-year results of 2 randomized clinical trials-TAP report. Arch Ophthalmol 1999;117(10):1329-45
    • (1999) Arch Ophthalmol , vol.117 , Issue.10 , pp. 1329-1345
  • 28
    • 0035124965 scopus 로고    scopus 로고
    • Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: Two-year results of 2 randomized clinical trials-Tap report 2
    • Bressler NM. Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: Two-year results of 2 randomized clinical trials-Tap report 2. Arch Ophthalmol 2001;119(2):198-207
    • (2001) Arch Ophthalmol , vol.119 , Issue.2 , pp. 198-207
    • Bressler, N.M.1
  • 29
    • 0035009086 scopus 로고    scopus 로고
    • Verteporfin therapy of subfoveal choroidal neovascularization in age-related macular degeneration: Two-year results of a randomized clinical trial including lesions with occult with no classic choroidal neovascularization-verteporfin in photodynamic therapy report 2
    • Verteporfin In Photodynamic Therapy Study Group
    • Verteporfin In Photodynamic Therapy Study Group. Verteporfin therapy of subfoveal choroidal neovascularization in age-related macular degeneration: Two-year results of a randomized clinical trial including lesions with occult with no classic choroidal neovascularization-verteporfin in photodynamic therapy report 2. Am J Ophthalmol 2001;131(5):541-60
    • (2001) Am J Ophthalmol , vol.131 , Issue.5 , pp. 541-560
  • 30
    • 16844375997 scopus 로고    scopus 로고
    • Verteporfin therapy of subfoveal minimally classic choroidal neovascularization in age-related macular degeneration: 2-year results of a randomized clinical trial
    • Azab M, Boyer DS, Bressler NM, et al. Verteporfin therapy of subfoveal minimally classic choroidal neovascularization in age-related macular degeneration: 2-year results of a randomized clinical trial. Arch Ophthalmol 2005;123(4):448-57
    • (2005) Arch Ophthalmol , vol.123 , Issue.4 , pp. 448-457
    • Azab, M.1    Boyer, D.S.2    Bressler, N.M.3
  • 31
    • 73549117001 scopus 로고    scopus 로고
    • Standard-fluence versus low-fluence photodynamic therapy in chronic central serous chorioretinopathy: A nonrandomized clinical trial
    • e2
    • Reibaldi M, Cardascia N, Longo A, et al. Standard-fluence versus low-fluence photodynamic therapy in chronic central serous chorioretinopathy: A nonrandomized clinical trial. Am J Ophthalmol 2010;149(2):307-15; e2
    • (2010) Am J Ophthalmol , vol.149 , Issue.2 , pp. 307-315
    • Reibaldi, M.1    Cardascia, N.2    Longo, A.3
  • 32
    • 0042029477 scopus 로고    scopus 로고
    • Combined photodynamic therapy with verteporfin and intravitreal triamcinolone acetonide for choroidal neovascularization
    • Spaide RF, Sorenson J, Maranan L. Combined photodynamic therapy with verteporfin and intravitreal triamcinolone acetonide for choroidal neovascularization. Ophthalmology 2003;110(8):1517-25
    • (2003) Ophthalmology , vol.110 , Issue.8 , pp. 1517-1525
    • Spaide, R.F.1    Sorenson, J.2    Maranan, L.3
  • 33
    • 13444273215 scopus 로고    scopus 로고
    • Photodynamic therapy with verteporfin combined with intravitreal injection of triamcinolone acetonide for choroidal neovascularization
    • Spaide RF, Sorenson J, Maranan L. Photodynamic therapy with verteporfin combined with intravitreal injection of triamcinolone acetonide for choroidal neovascularization. Ophthalmology 2005;112(2):301-4
    • (2005) Ophthalmology , vol.112 , Issue.2 , pp. 301-304
    • Spaide, R.F.1    Sorenson, J.2    Maranan, L.3
  • 34
    • 70350574107 scopus 로고    scopus 로고
    • Photodynamic therapy and intravitreal triamcinolone for neovascular age-related macular degeneration: A randomized clinical trial
    • e1
    • Maberley D. Photodynamic therapy and intravitreal triamcinolone for neovascular age-related macular degeneration: A randomized clinical trial. Ophthalmology 2009;116(11):2149-57; e1
    • (2009) Ophthalmology , vol.116 , Issue.11 , pp. 2149-2157
    • Maberley, D.1
  • 35
    • 33749451356 scopus 로고    scopus 로고
    • Ranibizumab versus verteporfin for neovascular age-related macular degeneration
    • Brown DM, Kaiser PK, Michels M, et al. Ranibizumab versus verteporfin for neovascular age-related macular degeneration. N Engl J Med 2006;355(14):1432-44
    • (2006) N Engl J Med , vol.355 , Issue.14 , pp. 1432-1444
    • Brown, D.M.1    Kaiser, P.K.2    Michels, M.3
  • 36
    • 57949094834 scopus 로고    scopus 로고
    • Ranibizumab versus verteporfin photodynamic therapy for neovascular age-related macular degeneration: Two-year results of the ANCHOR study
    • e5
    • Brown DM, Michels M, Kaiser PK, et al. Ranibizumab versus verteporfin photodynamic therapy for neovascular age-related macular degeneration: Two-year results of the ANCHOR study. Ophthalmology 2009;116(1):57-65; e5
    • (2009) Ophthalmology , vol.116 , Issue.1 , pp. 57-65
    • Brown, D.M.1    Michels, M.2    Kaiser, P.K.3
  • 37
    • 33749445317 scopus 로고    scopus 로고
    • Ranibizumab for neovascular age-related macular degeneration
    • Rosenfeld PJ, Brown DM, Heier JS, et al. Ranibizumab for neovascular age-related macular degeneration. N Engl J Med 2006;355(14):1419-31
    • (2006) N Engl J Med , vol.355 , Issue.14 , pp. 1419-1431
    • Rosenfeld, P.J.1    Brown, D.M.2    Heier, J.S.3
  • 38
    • 84860450956 scopus 로고    scopus 로고
    • Verteporfin plus ranibizumab for choroidal neovascularization in age-related macular degeneration: Twelve-month results of the DENALI study
    • Kaiser PK, Boyer DS, Cruess AF, et al. Verteporfin plus ranibizumab for choroidal neovascularization in age-related macular degeneration: Twelve-month results of the DENALI study. Ophthalmology 2012;119(5):1001-10
    • (2012) Ophthalmology , vol.119 , Issue.5 , pp. 1001-1010
    • Kaiser, P.K.1    Boyer, D.S.2    Cruess, A.F.3
  • 39
    • 84860452217 scopus 로고    scopus 로고
    • Verteporfin plus ranibizumab for choroidal neovascularization in age-related macular degeneration: Twelve-month MONT BLANC study results
    • Larsen M, Schmidt-Erfurth U, Lanzetta P, et al. Verteporfin plus ranibizumab for choroidal neovascularization in age-related macular degeneration: Twelve-month MONT BLANC study results. Ophthalmology 2012;119(5):992-1000
    • (2012) Ophthalmology , vol.119 , Issue.5 , pp. 992-1000
    • Larsen, M.1    Schmidt-Erfurth, U.2    Lanzetta, P.3
  • 40
    • 33846973642 scopus 로고    scopus 로고
    • Triple therapy for choroidal neovascularization due to age-related macular degeneration: Verteporfin PDT, bevacizumab, and dexamethasone
    • Augustin AJ, Puls S, Offermann I. Triple therapy for choroidal neovascularization due to age-related macular degeneration: Verteporfin PDT, bevacizumab, and dexamethasone. Retina 2007;27(2):133-40
    • (2007) Retina , vol.27 , Issue.2 , pp. 133-140
    • Augustin, A.J.1    Puls, S.2    Offermann, I.3
  • 41
    • 84865721295 scopus 로고    scopus 로고
    • EVEREST study: Efficacy and safety of verteporfin photodynamic therapy in combination with ranibizumab or alone versus ranibizumab monotherapy in patients with symptomatic macular polypoidal choroidal vasculopathy
    • Koh A, Lee WK, Chen LJ, et al. EVEREST study: Efficacy and safety of verteporfin photodynamic therapy in combination with ranibizumab or alone versus ranibizumab monotherapy in patients with symptomatic macular polypoidal choroidal vasculopathy. Retina 2012;32(8):1453-64
    • (2012) Retina , vol.32 , Issue.8 , pp. 1453-1464
    • Koh, A.1    Lee, W.K.2    Chen, L.J.3
  • 42
    • 0037407757 scopus 로고    scopus 로고
    • VEGF164 is proinflammatory in the diabetic retina
    • Ishida S, Usui T, Yamashiro K, et al. VEGF164 is proinflammatory in the diabetic retina. Invest Ophthalmol Vis Sci 2003;44(5):2155-62
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , Issue.5 , pp. 2155-2162
    • Ishida, S.1    Usui, T.2    Yamashiro, K.3
  • 43
    • 0043125643 scopus 로고    scopus 로고
    • VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization
    • Ishida S, Usui T, Yamashiro K, et al. VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization. J Exp Med 2003;198(3):483-9
    • (2003) J Exp Med , vol.198 , Issue.3 , pp. 483-489
    • Ishida, S.1    Usui, T.2    Yamashiro, K.3
  • 44
    • 0942287258 scopus 로고    scopus 로고
    • VEGF164(165) as the pathological isoform: Differential leukocyte and endothelial responses through VEGFR1 and VEGFR2
    • Usui T, Ishida S, Yamashiro K, et al. VEGF164(165) as the pathological isoform: Differential leukocyte and endothelial responses through VEGFR1 and VEGFR2. Invest Ophthalmol Vis Sci 2004;45(2):368-74
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , Issue.2 , pp. 368-374
    • Usui, T.1    Ishida, S.2    Yamashiro, K.3
  • 45
    • 11144239923 scopus 로고    scopus 로고
    • Pegaptanib for neovascular age-related macular degeneration
    • Gragoudas ES, Adamis AP, Cunningham ET Jr, et al. Pegaptanib for neovascular age-related macular degeneration. N Engl J Med 2004;351(27):2805-16
    • (2004) N Engl J Med , vol.351 , Issue.27 , pp. 2805-2816
    • Gragoudas, E.S.1    Adamis A, P.2    Cunningham Jr., E.T.3
  • 46
    • 57549094437 scopus 로고    scopus 로고
    • Pharmacotherapy of age-related macular degeneration
    • Ahmadi MA, Lim JI. Pharmacotherapy of age-related macular degeneration. Expert Opin Pharmacother 2008;9(17):3045-52
    • (2008) Expert Opin Pharmacother , vol.9 , Issue.17 , pp. 3045-3052
    • Ahmadi, M.A.1    Lim, J.I.2
  • 47
    • 84867074193 scopus 로고    scopus 로고
    • Treating early choroidal neovascularisation with pegaptanib sodium in patients with neovascular age-related macular degeneration: Findings of the PERSPECTIVES study
    • Chakravarthy U, Staurenghi G, Kwok K, et al. Treating early choroidal neovascularisation with pegaptanib sodium in patients with neovascular age-related macular degeneration: Findings of the PERSPECTIVES study. Br J Ophthalmol 2012;96(10):1351-4
    • (2012) Br J Ophthalmol , vol.96 , Issue.10 , pp. 1351-1354
    • Chakravarthy, U.1    Staurenghi, G.2    Kwok, K.3
  • 48
    • 79958012399 scopus 로고    scopus 로고
    • A Phase 23 Multicenter Randomized Double-masked 2-year Trial Of Pegaptanib Sodium For The Treatment Of Diabetic Macular Edema
    • Sultan MB, Zhou D, Loftus J, et al. A phase 2/3, multicenter, randomized, double-masked, 2-year trial of pegaptanib sodium for the treatment of diabetic macular edema. Ophthalmology 2011;118(6):1107-18
    • (2011) Ophthalmology , vol.118 , Issue.6 , pp. 1107-1118
    • Sultan, M.B.1    Zhou, D.2    Loftus, J.3
  • 49
    • 65249132359 scopus 로고    scopus 로고
    • Pegaptanib sodium for macular edema secondary to central retinal vein occlusion
    • Wroblewski JJ, Wells JA III, Adamis AP, et al. Pegaptanib sodium for macular edema secondary to central retinal vein occlusion. Arch Ophthalmol 2009;127(4):374-80
    • (2009) Arch Ophthalmol , vol.127 , Issue.4 , pp. 374-380
    • Wroblewski, J.J.1    Wells III, J.A.2    Adamis, A.P.3
  • 50
    • 72049090107 scopus 로고    scopus 로고
    • Pegaptanib sodium for macular edema secondary to branch retinal vein occlusion
    • Wroblewski JJ, Wells JA III, Gonzales CR. Pegaptanib sodium for macular edema secondary to branch retinal vein occlusion. Am J Ophthalmol 2010;149(1):147-54
    • (2010) Am J Ophthalmol , vol.149 , Issue.1 , pp. 147-154
    • Wroblewski, J.J.1    Wells III, J.A.2    Gonzales, C.R.3
  • 51
    • 51649109046 scopus 로고    scopus 로고
    • Intraocular pharmacokinetics of bevacizumab after a single intravitreal injection in humans
    • Krohne TU, Eter N, Holz FG, Meyer CH. Intraocular pharmacokinetics of bevacizumab after a single intravitreal injection in humans. Am J Ophthalmol 2008;146(4):508-12
    • (2008) Am J Ophthalmol , vol.146 , Issue.4 , pp. 508-512
    • Krohne, T.U.1    Eter, N.2    Holz, F.G.3    Meyer, C.H.4
  • 52
    • 84866398752 scopus 로고    scopus 로고
    • Intraocular pharmacokinetics of ranibizumab following a single intravitreal injection in humans
    • e2
    • Krohne TU, Liu Z, Holz FG, Meyer CH. Intraocular pharmacokinetics of ranibizumab following a single intravitreal injection in humans. Am J Ophthalmol 2012;154(4):682-6; e2
    • (2012) Am J Ophthalmol , vol.154 , Issue.4 , pp. 682-686
    • Krohne, T.U.1    Liu, Z.2    Holz F, G.3    Meyer, C.H.4
  • 53
    • 20144372969 scopus 로고    scopus 로고
    • Systemic bevacizumab (Avastin) therapy for neovascular age-related macular degeneration twelve-week results of an uncontrolled open-label clinical study
    • Michels S, Rosenfeld PJ, Puliafito CA, et al. Systemic bevacizumab (Avastin) therapy for neovascular age-related macular degeneration twelve-week results of an uncontrolled open-label clinical study. Ophthalmology 2005;112(6):1035-47
    • (2005) Ophthalmology , vol.112 , Issue.6 , pp. 1035-1047
    • Michels, S.1    Rosenfeld, P.J.2    Puliafito, C.A.3
  • 54
    • 33750305221 scopus 로고    scopus 로고
    • Systemic bevacizumab (Avastin) therapy for neovascular age-related macular degeneration: Twenty-four-week results of an uncontrolled open-label clinical study
    • 2002 e1-2002 12
    • Moshfeghi AA, Rosenfeld PJ, Puliafito CA, et al. Systemic bevacizumab (Avastin) therapy for neovascular age-related macular degeneration: Twenty-four-week results of an uncontrolled open-label clinical study. Ophthalmology 2006;113(11):2002; e1-12
    • (2006) Ophthalmology , vol.113 , Issue.11
    • Moshfeghi, A.A.1    Rosenfeld, P.J.2    Puliafito, C.A.3
  • 55
    • 23044505200 scopus 로고    scopus 로고
    • Optical coherence tomography findings after an intravitreal injection of bevacizumab (Avastin) for neovascular age-related macular degeneration
    • Rosenfeld PJ, Moshfeghi AA, Puliafito CA. Optical coherence tomography findings after an intravitreal injection of bevacizumab (Avastin) for neovascular age-related macular degeneration. Ophthalmic Surg Lasers Imaging 2005;36(4):331-5
    • (2005) Ophthalmic Surg Lasers Imaging , vol.36 , Issue.4 , pp. 331-335
    • Rosenfeld, P.J.1    Moshfeghi, A.A.2    Puliafito, C.A.3
  • 56
    • 79955085045 scopus 로고    scopus 로고
    • Pharmacotherapy for neovascular age-related macular degeneration: An analysis of the 100%
    • e1 medicare fee-for-service part B claims file
    • Brechner RJ, Rosenfeld PJ, Babish JD, Caplan S. Pharmacotherapy for neovascular age-related macular degeneration: An analysis of the 100% 2008 medicare fee-for-service part B claims file. Am J Ophthalmol 2011;151(5):887-95; e1
    • (2008) Am J Ophthalmol , vol.151 , Issue.5 , pp. 887-895
    • Brechner, R.J.1    Rosenfeld, P.J.2    Babish, J.D.3    Caplan, S.4
  • 57
    • 84862914622 scopus 로고    scopus 로고
    • Avastin doesn't blind people, people blind people
    • e1
    • Gonzalez S, Rosenfeld PJ, Stewart MW, et al. Avastin doesn't blind people, people blind people. Am J Ophthalmol 2012;153(2):196-203; e1
    • (2012) Am J Ophthalmol , vol.153 , Issue.2 , pp. 196-203
    • Gonzalez, S.1    Rosenfeld, P.J.2    Stewart, M.W.3
  • 58
    • 84863320414 scopus 로고    scopus 로고
    • Ranibizumab and bevacizumab for treatment of neovascular age-related macular degeneration: Two-year results
    • Martin DF, Maguire MG, Fine SL, et al. Ranibizumab and bevacizumab for treatment of neovascular age-related macular degeneration: Two-year results. Ophthalmology 2012;119(7):1388-98
    • (2012) Ophthalmology , vol.119 , Issue.7 , pp. 1388-1398
    • Martin, D.F.1    Maguire, M.G.2    Fine, S.L.3
  • 59
    • 79956218863 scopus 로고    scopus 로고
    • Ranibizumab and bevacizumab for neovascular age-related macular degeneration
    • Martin DF, Maguire MG, Ying GS, et al. Ranibizumab and bevacizumab for neovascular age-related macular degeneration. N Engl J Med 2011;364(20):1897-908
    • (2011) N Engl J Med , vol.364 , Issue.20 , pp. 1897-1908
    • Martin, D.F.1    Maguire, M.G.2    Ying, G.S.3
  • 60
    • 84863327423 scopus 로고    scopus 로고
    • Ranibizumab versus bevacizumab to treat neovascular age-related macular degeneration: One-year findings from the IVAN randomized trial
    • Chakravarthy U, Harding SP, Rogers CA, et al. Ranibizumab versus bevacizumab to treat neovascular age-related macular degeneration: One-year findings from the IVAN randomized trial. Ophthalmology 2012;119(7):1399-411
    • (2012) Ophthalmology , vol.119 , Issue.7 , pp. 1399-1411
    • Chakravarthy, U.1    Harding, S.P.2    Rogers, C.A.3
  • 61
    • 84874654113 scopus 로고    scopus 로고
    • A randomised double-masked trial comparing the visual outcome after treatment with ranibizumab or bevacizumab in patients with neovascular age-related macular degeneration
    • Krebs I, Schmetterer L, Boltz A, et al. A randomised double-masked trial comparing the visual outcome after treatment with ranibizumab or bevacizumab in patients with neovascular age-related macular degeneration. Br J Ophthalmol 2013;97(3):266-71
    • (2013) Br J Ophthalmol , vol.97 , Issue.3 , pp. 266-271
    • Krebs, I.1    Schmetterer, L.2    Boltz, A.3
  • 62
    • 36749003833 scopus 로고    scopus 로고
    • Pharmacokinetics and retinal distribution of ranibizumab, a humanized antibody fragment directed against VEGF-A, following intravitreal administration in rabbits
    • Gaudreault J, Fei D, Beyer JC, et al. Pharmacokinetics and retinal distribution of ranibizumab, a humanized antibody fragment directed against VEGF-A, following intravitreal administration in rabbits. Retina 2007;27(9):1260-6
    • (2007) Retina , vol.27 , Issue.9 , pp. 1260-1266
    • Gaudreault, J.1    Fei, D.2    Beyer, J.C.3
  • 63
    • 0032864292 scopus 로고    scopus 로고
    • Comparisons of the intraocular tissue distribution, pharmacokinetics, and safety of 125I-labeled full-length and Fab antibodies in rhesus monkeys following intravitreal administration
    • Mordenti J, Cuthbertson RA, Ferrara N, et al. Comparisons of the intraocular tissue distribution, pharmacokinetics, and safety of 125I-labeled full-length and Fab antibodies in rhesus monkeys following intravitreal administration. Toxicol Pathol 1999;27(5):536-44
    • (1999) Toxicol Pathol , vol.27 , Issue.5 , pp. 536-544
    • Mordenti, J.1    Cuthbertson, R.A.2    Ferrara, N.3
  • 64
    • 13944266313 scopus 로고    scopus 로고
    • Preclinical pharmacokinetics of ranibizumab (rhuFabV2) after a single intravitreal administration
    • Gaudreault J, Fei D, Rusit J, et al. Preclinical pharmacokinetics of ranibizumab (rhuFabV2) after a single intravitreal administration. Invest Ophthalmol Vis Sci 2005;46(2):726-33
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , Issue.2 , pp. 726-733
    • Gaudreault, J.1    Fei, D.2    Rusit, J.3
  • 65
    • 85027955048 scopus 로고    scopus 로고
    • Pharmacokinetic rationale for dosing every 2 weeks versus 4 weeks with intravitreal ranibizumab, bevacizumab, and aflibercept (vascular endothelial growth factor Trap-eye
    • Stewart MW, Rosenfeld PJ, Penha FM, et al. Pharmacokinetic rationale for dosing every 2 weeks versus 4 weeks with intravitreal ranibizumab, bevacizumab, and aflibercept (vascular endothelial growth factor Trap-eye). Retina 2012;32(3):434-57
    • (2012) Retina , vol.32 , Issue.3 , pp. 434-457
    • Stewart, M.W.1    Rosenfeld, P.J.2    Penha, F.M.3
  • 66
    • 76149118115 scopus 로고    scopus 로고
    • Morphological and functional analysis of the loading regimen with intravitreal ranibizumab in neovascular age-related macular degeneration
    • Bolz M, Simader C, Ritter M, et al. Morphological and functional analysis of the loading regimen with intravitreal ranibizumab in neovascular age-related macular degeneration. Br J Ophthalmol 2010;94(2):185-9
    • (2010) Br J Ophthalmol , vol.94 , Issue.2 , pp. 185-189
    • Bolz, M.1    Simader, C.2    Ritter, M.3
  • 67
    • 69249222585 scopus 로고    scopus 로고
    • A Phase IIIb study to evaluate the safety of ranibizumab in subjects with neovascular age-related macular degeneration
    • Boyer DS, Heier JS, Brown DM, et al. A Phase IIIb study to evaluate the safety of ranibizumab in subjects with neovascular age-related macular degeneration. Ophthalmology 2009;116(9):1731-9
    • (2009) Ophthalmology , vol.116 , Issue.9 , pp. 1731-1739
    • Boyer, D.S.1    Heier, J.S.2    Brown, D.M.3
  • 68
    • 33947403618 scopus 로고    scopus 로고
    • An optical coherence tomography-guided, variable dosing regimen with intravitreal ranibizumab (Lucentis) for neovascular age-related macular degeneration
    • Fung AE, Lalwani GA, Rosenfeld PJ, et al. An optical coherence tomography-guided, variable dosing regimen with intravitreal ranibizumab (Lucentis) for neovascular age-related macular degeneration. Am J Ophthalmol 2007;143(4):566-83
    • (2007) Am J Ophthalmol , vol.143 , Issue.4 , pp. 566-583
    • Fung, A.E.1    Lalwani, G.A.2    Rosenfeld, P.J.3
  • 69
    • 79953295148 scopus 로고    scopus 로고
    • Safety and efficacy of a flexible dosing regimen of ranibizumab in neovascular age-related macular degeneration: The sustain study
    • Holz FG, Amoaku W, Donate J, et al. Safety and efficacy of a flexible dosing regimen of ranibizumab in neovascular age-related macular degeneration: The SUSTAIN study. Ophthalmology 2011;118(4):663-71
    • (2011) Ophthalmology , vol.118 , Issue.4 , pp. 663-671
    • Holz, F.G.1    Amoaku, W.2    Donate, J.3
  • 70
    • 67149101784 scopus 로고    scopus 로고
    • A variable-dosing regimen with intravitreal ranibizumab for neovascular age-related macular degeneration: Year 2 of the PrONTO Study
    • e1
    • Lalwani GA, Rosenfeld PJ, Fung AE, et al. A variable-dosing regimen with intravitreal ranibizumab for neovascular age-related macular degeneration: year 2 of the PrONTO Study. Am J Ophthalmol 2009;148(1):43-58; e1
    • (2009) Am J Ophthalmol , vol.148 , Issue.1 , pp. 43-58
    • Lalwani, G.A.1    Rosenfeld, P.J.2    Fung, A.E.3
  • 71
    • 73349096955 scopus 로고    scopus 로고
    • Treat and extend" ; Dosing of intravitreal antivascular endothelial growth factor therapy for type 3 neovascularization/ retinal angiomatous proliferation
    • Engelbert M, Zweifel SA, Freund KB. " ;Treat and extend" ; Dosing of intravitreal antivascular endothelial growth factor therapy for type 3 neovascularization/ retinal angiomatous proliferation. Retina 2009;29(10):1424-31
    • (2009) Retina , vol.29 , Issue.10 , pp. 1424-1431
    • Engelbert, M.1    Zweifel, S.A.2    Freund, K.B.3
  • 72
    • 78049267612 scopus 로고    scopus 로고
    • Long-Term follow-up for type 1 (subretinal pigment epithelium) neovascularization using a modified " ;treat and extend" ; Dosing regimen of intravitreal antivascular endothelial growth factor therapy
    • Engelbert M, Zweifel SA, Freund KB. Long-Term follow-up for type 1 (subretinal pigment epithelium) neovascularization using a modified " ;treat and extend" ; Dosing regimen of intravitreal antivascular endothelial growth factor therapy. Retina 2010;30(9):1368-75
    • (2010) Retina , vol.30 , Issue.9 , pp. 1368-1375
    • Engelbert, M.1    Zweifel, S.A.2    Freund, K.B.3
  • 73
    • 78049279239 scopus 로고    scopus 로고
    • A Treat and extend regimen using ranibizumab for neovascular age-related macular degeneration clinical and economic impact
    • Gupta OP, Shienbaum G, Patel AH, et al. A treat and extend regimen using ranibizumab for neovascular age-related macular degeneration clinical and economic impact. Ophthalmology 2010;117(11):2134-40
    • (2010) Ophthalmology , vol.117 , Issue.11 , pp. 2134-2140
    • Gupta, O.P.1    Shienbaum, G.2    Patel, A.H.3
  • 74
    • 78651371501 scopus 로고    scopus 로고
    • Inject and extend dosing versus dosing as needed: A comparative retrospective study of ranibizumab in exudative age-related macular degeneration
    • Oubraham H, Cohen SY, Samimi S, et al. Inject and extend dosing versus dosing as needed: A comparative retrospective study of ranibizumab in exudative age-related macular degeneration. Retina 2011;31(1):26-30
    • (2011) Retina , vol.31 , Issue.1 , pp. 26-30
    • Oubraham, H.1    Cohen, S.Y.2    Samimi, S.3
  • 75
    • 0037231664 scopus 로고    scopus 로고
    • Cytokine traps: Multi-component, high-Affinity blockers of cytokine action
    • Economides AN, Carpenter LR, Rudge JS, et al. Cytokine traps: Multi-component, high-Affinity blockers of cytokine action. Nat Med 2003;9(1):47-52
    • (2003) Nat Med , vol.9 , Issue.1 , pp. 47-52
    • Economides, A.N.1    Carpenter, L.R.2    Rudge, J.S.3
  • 76
    • 0037143764 scopus 로고    scopus 로고
    • VEGF-Trap: A VEGF blocker with potent antitumor effects
    • Holash J, Davis S, Papadopoulos N, et al. VEGF-Trap: A VEGF blocker with potent antitumor effects. Proc Natl Acad Sci USA 2002;99(17):11393-8
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.17 , pp. 11393-11398
    • Holash, J.1    Davis, S.2    Papadopoulos, N.3
  • 77
    • 84857250733 scopus 로고    scopus 로고
    • Intravitreal aflibercept injection for neovascular (wet) age-related macular degeneration
    • Ohr M, Kaiser PK. Intravitreal aflibercept injection for neovascular (wet) age-related macular degeneration. Expert Opin Pharmacother 2012;13(4):585-91
    • (2012) Expert Opin Pharmacother , vol.13 , Issue.4 , pp. 585-591
    • Ohr, M.1    Kaiser, P.K.2
  • 78
    • 84861722422 scopus 로고    scopus 로고
    • What are the half-lives of ranibizumab and aflibercept (vegf trap-eye) in human eyes? calculations with a mathematical model
    • Stewart MW. What are the half-lives of ranibizumab and aflibercept (VEGF Trap-eye) in human eyes? Calculations with a mathematical model. Eye Rep 2011;1(1):e5
    • (2011) Eye Rep , vol.1 , Issue.1
    • Stewart, M.W.1
  • 79
    • 84870723704 scopus 로고    scopus 로고
    • Intravitreal aflibercept (VEGF Trap-Eye) in wet age-related macular degeneration
    • Heier JS, Brown DM, Chong V, et al. Intravitreal aflibercept (VEGF Trap-Eye) in wet age-related macular degeneration. Ophthalmology 2012;119(12):2537-48
    • (2012) Ophthalmology , vol.119 , Issue.12 , pp. 2537-2548
    • Heier, J.S.1    Brown, D.M.2    Chong, V.3
  • 80
    • 84866370357 scopus 로고    scopus 로고
    • Aflibercept for age-related macular degeneration: A game-changer or quiet addition?
    • Browning DJ, Kaiser PK, Rosenfeld PJ, Stewart MW. Aflibercept for age-related macular degeneration: A game-changer or quiet addition? Am J Ophthalmol 2012;154(2):222-6
    • (2012) Am J Ophthalmol , vol.154 , Issue.2 , pp. 222-226
    • Browning, D.J.1    Kaiser, P.K.2    Rosenfeld, P.J.3    Stewart, M.W.4
  • 81
    • 70349200939 scopus 로고    scopus 로고
    • Switching biologic agents for uveitis
    • Lond
    • Dhingra N, Morgan J, Dick AD. Switching biologic agents for uveitis. Eye (Lond) 2009;23(9):1868-70
    • (2009) Eye , vol.23 , Issue.9 , pp. 1868-1870
    • Dhingra, N.1    Morgan, J.2    Dick, A.D.3
  • 82
    • 33744728068 scopus 로고    scopus 로고
    • Inhibition of platelet-derived growth factor B signaling enhances the efficacy of anti-vascular endothelial growth factor therapy in multiple models of ocular neovascularization
    • Jo N, Mailhos C, Ju M, et al. Inhibition of platelet-derived growth factor B signaling enhances the efficacy of anti-vascular endothelial growth factor therapy in multiple models of ocular neovascularization. Am J Pathol 2006;168(6):2036-53
    • (2006) Am J Pathol , vol.168 , Issue.6 , pp. 2036-2053
    • Jo, N.1    Mailhos, C.2    Ju, M.3
  • 83
    • 0042780350 scopus 로고    scopus 로고
    • Designing repeat proteins: Well-expressed, soluble and stable proteins from combinatorial libraries of consensus ankyrin repeat proteins
    • Binz HK, Stumpp MT, Forrer P, et al. Designing repeat proteins: Well-expressed, soluble and stable proteins from combinatorial libraries of consensus ankyrin repeat proteins. J Mol Biol 2003;332(2):489-503
    • (2003) J Mol Biol , vol.332 , Issue.2 , pp. 489-503
    • Binz, H.K.1    Stumpp, M.T.2    Forrer, P.3
  • 84
    • 84877652903 scopus 로고    scopus 로고
    • Treatment of diabetic macular edema with a designed ankyrin repeat protein that binds vascular endothelial growth factor: A phase 1/2 study
    • [ Epub ahead of print]
    • Campochiaro PA, Channa R, Berger BB, et al. Treatment of diabetic macular edema with a designed ankyrin repeat protein that binds vascular endothelial growth factor: A phase 1/2 study. Am J Ophthalmol 2012; [Epub ahead of print]
    • (2012) Am J Ophthalmol
    • Campochiaro, P.A.1    Channa, R.2    Berger, B.B.3
  • 85
    • 77958524704 scopus 로고    scopus 로고
    • Pathway-based therapies for age-related macular degeneration: An integrated survey of emerging treatment alternatives
    • Zarbin MA, Rosenfeld PJ. Pathway-based therapies for age-related macular degeneration: An integrated survey of emerging treatment alternatives. Retina 2010;30(9):1350-67
    • (2010) Retina , vol.30 , Issue.9 , pp. 1350-1367
    • Zarbin, M.A.1    Rosenfeld, P.J.2
  • 86
    • 33748787141 scopus 로고    scopus 로고
    • Squalamine lactate for exudative age-related macular degeneration
    • 6
    • Connolly B, Desai A, Garcia CA, et al. Squalamine lactate for exudative age-related macular degeneration. Ophthalmol Clin North Am 2006;19(3):381-91, vi
    • (2006) Ophthalmol Clin North Am , vol.19 , Issue.3 , pp. 381-391
    • Connolly, B.1    Desai, A.2    Garcia, C.A.3
  • 87
    • 77958554327 scopus 로고    scopus 로고
    • Do we need a new classification for choroidal neovascularization in age-related macular degeneration?
    • 87. Freund KB, Zweifel SA, Engelbert M. Do we need a new classification for choroidal neovascularization in age-related macular degeneration? Retina 2010;30(9):1333-49
    • (2010) Retina , vol.30 , Issue.9 , pp. 1333-1349
    • Freund, K.B.1    Zweifel, S.A.2    Engelbert, M.3
  • 88
    • 0028142135 scopus 로고
    • Biomicroscopic and histopathologic considerations regarding the feasibility of surgical excision of subfoveal neovascular membranes
    • Gass JD. Biomicroscopic and histopathologic considerations regarding the feasibility of surgical excision of subfoveal neovascular membranes. Am J Ophthalmol 1994;118(3):285-98
    • (1994) Am J Ophthalmol , vol.118 , Issue.3 , pp. 285-298
    • Gass, J.D.1
  • 89
    • 84865129521 scopus 로고    scopus 로고
    • Binding and neutralization of vascular endothelial growth factor (vegf) and related ligands by vegf trap ranibizumab and bevacizumab
    • Papadopoulos N, Martin J, Ruan Q, et al. Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab. Angiogenesis 2012;15(2):171-85
    • (2012) Angiogenesis , vol.15 , Issue.2 , pp. 171-185
    • Papadopoulos, N.1    Martin, J.2    Ruan, Q.3
  • 90
    • 0345827805 scopus 로고    scopus 로고
    • Technology evaluation: Pegaptanib, Eyetech/Pfizer
    • Vinores SA. Technology evaluation: Pegaptanib, Eyetech/Pfizer. Curr Opin Mol Ther 2003;5(6):673-9
    • (2003) Curr Opin Mol Ther , vol.5 , Issue.6 , pp. 673-679
    • Vinores, S.A.1
  • 91
    • 33747891752 scopus 로고    scopus 로고
    • Year 2 efficacy results of 2 randomized controlled clinical trials of pegaptanib for neovascular age-related macular degeneration
    • 1508
    • Chakravarthy U, Adamis AP, Cunningham ET Jr, et al. Year 2 efficacy results of 2 randomized controlled clinical trials of pegaptanib for neovascular age-related macular degeneration. Ophthalmology 2006;113(9):1508; e1-25
    • (2006) Ophthalmology , vol.113 , Issue.9
    • Chakravarthy, U.1    Adamis A, P.2    Cunningham Jr., E.T.3


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