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Volumn 5, Issue 3, 2013, Pages 174-182

Identification of a small molecule activator of SIRT1 gene expression

Author keywords

Gene expression; Senescence; SIRT1; Small molecule activator; Syringaresinol

Indexed keywords


EID: 84877640253     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100539     Document Type: Article
Times cited : (22)

References (13)
  • 1
    • 79952806932 scopus 로고    scopus 로고
    • Sirtuins at a glance
    • Nakagawa T and Guarente L. Sirtuins at a glance. J Cell Sci. 2011; 124:833-838.
    • (2011) J Cell Sci , vol.124 , pp. 833-838
    • Nakagawa, T.1    Guarente, L.2
  • 2
    • 79958206937 scopus 로고    scopus 로고
    • Epstein Lecture: Sirtuins, aging, and medicine
    • Guarente L. Franklin H. Epstein Lecture: Sirtuins, aging, and medicine. N Engl J Med. 2011; 364:2235-2244.
    • (2011) N Engl J Med , vol.364 , pp. 2235-2244
    • Guarente, L.1    Franklin, H.2
  • 3
    • 77957579920 scopus 로고    scopus 로고
    • Impact of Sirt1 on mammalian aging
    • Herranz D and Serrano M. Impact of Sirt1 on mammalian aging. Aging (Albany NY). 2010; 2:315-316.
    • (2010) Aging (Albany NY) , vol.2 , pp. 315-316
    • Herranz, D.1    Serrano, M.2
  • 5
    • 77949887506 scopus 로고    scopus 로고
    • Mammalian sirtuins: biological insights and disease relevance
    • Haigis MC and Sinclair DA. Mammalian sirtuins: biological insights and disease relevance. Annu Rev Pathol. 2010; 5:253-295.
    • (2010) Annu Rev Pathol , vol.5 , pp. 253-295
    • Haigis, M.C.1    Sinclair, D.A.2
  • 6
    • 80052799903 scopus 로고    scopus 로고
    • Emerging roles of SIRT1 deacetylase in regulating cardiomyocyte survival and hypertrophy
    • Sundaresan NR, Pillai VB and Gupta MP. Emerging roles of SIRT1 deacetylase in regulating cardiomyocyte survival and hypertrophy. J Mol Cell Cardiol. 2011; 51:614-618.
    • (2011) J Mol Cell Cardiol , vol.51 , pp. 614-618
    • Sundaresan, N.R.1    Pillai, V.B.2    Gupta, M.P.3
  • 7
    • 53249121556 scopus 로고    scopus 로고
    • Sirtuins--novel therapeutic targets to treat age-associated diseases
    • Lavu S, Boss O, Elliott PJ and Lambert PD. Sirtuins--novel therapeutic targets to treat age-associated diseases. Nat Rev Drug Discov. 2008; 7:841-853.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 841-853
    • Lavu, S.1    Boss, O.2    Elliott, P.J.3    Lambert, P.D.4
  • 8
    • 40849135481 scopus 로고    scopus 로고
    • The Sirtuin family: therapeutic targets to treat diseases of aging
    • Milne JC and Denu JM. The Sirtuin family: therapeutic targets to treat diseases of aging. Curr Opin Chem Biol. 2008; 12:11-17.
    • (2008) Curr Opin Chem Biol , vol.12 , pp. 11-17
    • Milne, J.C.1    Denu, J.M.2
  • 9
    • 80052083866 scopus 로고    scopus 로고
    • Resveratrol-activated SIRT1 in liver and pancreatic beta-cells: a Janus head looking to the same direction of metabolic homeostasis
    • Vetterli L and Maechler P. Resveratrol-activated SIRT1 in liver and pancreatic beta-cells: a Janus head looking to the same direction of metabolic homeostasis. Aging (Albany NY). 2011; 3:444-449.
    • (2011) Aging (Albany NY) , vol.3 , pp. 444-449
    • Vetterli, L.1    Maechler, P.2
  • 10
    • 77952496696 scopus 로고    scopus 로고
    • SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells
    • Zu Y, Liu L, Lee MY, Xu C, Liang Y, Man RY, Vanhoutte PM and Wang Y. SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells. Circ Res. 2010; 106:1384-1393.
    • (2010) Circ Res , vol.106 , pp. 1384-1393
    • Zu, Y.1    Liu, L.2    Lee, M.Y.3    Xu, C.4    Liang, Y.5    Man, R.Y.6    Vanhoutte, P.M.7    Wang, Y.8
  • 11
    • 35349011597 scopus 로고    scopus 로고
    • Sirt1 modulates premature senescence-like phenotype in human endothelial cells
    • Ota H, Akishita M, Eto M, Iijima K, Kaneki M and Ouchi Y. Sirt1 modulates premature senescence-like phenotype in human endothelial cells. J Mol Cell Cardiol. 2007; 43:571-579.
    • (2007) J Mol Cell Cardiol , vol.43 , pp. 571-579
    • Ota, H.1    Akishita, M.2    Eto, M.3    Iijima, K.4    Kaneki, M.5    Ouchi, Y.6
  • 12
    • 54149103338 scopus 로고    scopus 로고
    • Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice
    • Zhang QJ, Wang Z, Chen HZ, Zhou S, Zheng W, Liu G, Wei YS, Cai H, Liu DP and Liang CC. Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice. Cardiovasc Res. 2008; 80:191-199.
    • (2008) Cardiovasc Res , vol.80 , pp. 191-199
    • Zhang, Q.J.1    Wang, Z.2    Chen, H.Z.3    Zhou, S.4    Zheng, W.5    Liu, G.6    Wei, Y.S.7    Cai, H.8    Liu, D.P.9    Liang, C.C.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.