Eosinophil extracellular DNA trap cell death mediates lytic release of free secretion-competent eosinophil granules in humans

Blood

Volumn 121, Issue 11, 2013, Pages 2074-2083

  Ueki, Shigeharu ^a,b   Melo, Rossana C N ^a,c   Ghiran, Ionita ^a   Spencer, Lisa A ^a   Dvorak, Ann M ^a   Weller, Peter F ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b AKITA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c FEDERAL UNIVERSITY OF JUIZ DE FORA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM IONOPHORE; CELL DNA; CELL NUCLEUS DNA; CYTOKINE; EOTAXIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; PHORBOL 13 ACETATE 12 MYRISTATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; THROMBOCYTE ACTIVATING FACTOR; DNA;

ARTICLE; CELL BUDDING; CELL DEATH; CELL DISRUPTION; CELL GRANULE; CELL MEMBRANE; CELLULAR SECRETION; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOLYSIS; EOSINOPHIL; EXTRACELLULAR TRAP; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; PRIORITY JOURNAL; CELL CULTURE; DEGRANULATION; DOSE RESPONSE; DRUG EFFECT; EXOCYTOSIS; EXTRACELLULAR SPACE; GENETICS; METABOLISM; PHYSIOLOGY; SECRETION (PROCESS); SECRETORY VESICLE;

CELL DEATH; CELL DEGRANULATION; CELL MEMBRANE; CELLS, CULTURED; CHEMOKINE CCL11; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; EOSINOPHILS; EXOCYTOSIS; EXTRACELLULAR SPACE; HUMANS; SECRETORY VESICLES;

MLCS; MLOWN;

EID: 84877622192     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-05-432088     Document Type: Article

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