Human monoclonal ScFv that bind to different functional domains of M2 and inhibit H5N1 influenza virus replication

Virology Journal

Volumn 10, Issue , 2013, Pages

  Pissawong, Tippawan ^a   Maneewatch, Santi ^a   Thueng In, Kanyarat ^b   Srimanote, Potjanee ^c   Dong Din On, Fonthip ^b   Thanongsaksrikul, Jeeraphong ^c   Songserm, Thaweesak ^d   Tongtawe, Pongsri ^c   Bangphoomi, Kunan ^b   Chaicumpa, Wanpen ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

^b KASETSART UNIVERSITY   (Thailand)

^c THAMMASAT UNIVERSITY   (Thailand)

^d KASETSART UNIVERSITY   (Thailand)

Author keywords

H5N1; Human ScFv; Influenza virus; M2 protein; Mimotope; Molecular docking; Phage display; Quantitative real time RT PCR; Virus neutralization

Indexed keywords

ADAMANTANE; EPITOPE; GLUTATHIONE TRANSFERASE M2; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

AMINO ACID SEQUENCE; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ARTICLE; AUTOPHAGY; BIOPANNING; CLADISTICS; COMPUTER MODEL; CONTROLLED STUDY; CYTOPLASM; ESCHERICHIA COLI; HETEROLOGOUS EXPRESSION; HOMOLOGOUS RECOMBINATION; INFLUENZA A (H5N1); INFLUENZA VIRUS A H5N1; MIMOTOPE; MOLECULAR DOCKING; NONHUMAN; PHAGE DISPLAY; PHAGEMID; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; VIRUS ASSEMBLY; VIRUS MORPHOGENESIS; VIRUS NEUTRALIZATION; VIRUS RELEASE; VIRUS REPLICATION;

ORTHOMYXOVIRIDAE;

EID: 84877619861     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-10-148     Document Type: Article

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