Tear osmolarity and ocular surface changes in patient with polycystic ovary syndrome

Current Eye Research

Volumn 38, Issue 6, 2013, Pages 621-625

  Gonen, Tansu ^a   Celik, Cem ^a   Oznur, Meltem ^a   Abali, Remzi ^a   Gonen, Korcan A ^a   Horozoglu, Fatih ^a   Aksu, Erson ^a   Keskinbora, Kadircan H ^a  

^a NAMIK KEMAL UNIVERSITY   (Turkey)

Author keywords

Conjunctival impression cytology; Dry eye; Ocular surface; Polycystic ovary syndrome; Tear osmolarity

Indexed keywords

INSULIN; TESTOSTERONE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONJUNCTIVAL HYPEREMIA; CONTROLLED STUDY; FEMALE; HUMAN; IMPRESSION CYTOLOGY; INSULIN BLOOD LEVEL; LACRIMAL FLUID; MEIBOMIAN GLAND; MUCUS SECRETION; OBSERVATIONAL STUDY; OCULAR SURFACE DISEASE; OSMOLARITY; OVARY POLYCYSTIC DISEASE; PRIORITY JOURNAL; PROSPECTIVE STUDY; SQUAMOUS CELL METAPLASIA; TEAR FILM; TESTOSTERONE BLOOD LEVEL;

ADULT; CONJUNCTIVAL DISEASES; CORNEAL DISEASES; DRY EYE SYNDROMES; FEMALE; HUMANS; HYPERANDROGENISM; OSMOLAR CONCENTRATION; POLYCYSTIC OVARY SYNDROME; PROSPECTIVE STUDIES; TEARS; YOUNG ADULT;

EID: 84877608120     PISSN: 02713683     EISSN: 14602202     Source Type: Journal    
DOI: 10.3109/02713683.2012.749917     Document Type: Article

References (23)

1. Asuncia M, Calvo RM, San Milla JL, Sancho J, Avila S, Escobar-Morreale HF. A prospective study of the prevalence of the polycystic ovary syndrome in unselected Caucasian women from Spain. J Clin Endocrinol Metab 2000; 85: 2434-2438. (Pubitemid 32269197)
2. Azziz R, Woods KS, Reyna R, Key TJ, Knochenhauer ES, Yildiz BO. The prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab 2004; 89: 2745-2749. (Pubitemid 38766360)
3. Knochenhauer ES, Key TJ, Kahsar-Miller M, Waggoner W, Boots LR, Azziz R. Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study. J Clin Endocrinol Metab 1998; 83: 3078-3082. (Pubitemid 28500937)
4. Goodarzi MO, Dumesic DA, Chazenbalk G, Azziz R. Polycystic ovary syndrome: etiology, pathogenesis and diagnosis. Nat Rev Endocrinol 2011; 7: 219-231.
5. Rotterdam ESHRE/ASRM-Sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod. 2004; 19: 41-47.
6. Cibula D, CokovaR, Fanta M, Poledne R, Zivny J, Skibová J. Increased risk of non-insulin dependent diabetes mellitus, arterial hypertension and coronary artery disease in perimenopausal women with a history of the polycystic ovary syndrome. Hum Reprod 2000; 15: 785-789. (Pubitemid 30192723)
7. Sullivan DA, Hann LE. Hormonal infl uence on the secretory immune system of the eye: endocrine impact on the lacrimal gland accumulation and secretion of IgA and IgG. J Steroid Biochem 1989; 34: 253-262. (Pubitemid 20061790)
8. Mitchell S, Abel P, Madaan S, Jeffs J, Chaudhary K, Stamp G et al. Androgen-dependent regulation of human MUC1 mucin expression. Neoplasia 2002; 4: 9-18. (Pubitemid 34075886)
9. Yavas GF, Ozturk F, Kusbeci T, Ermis SS, Yilmazer M, Cevrioglu S et al. Meibomian gland alterations in polycystic ovary syndrome. Curr Eye Res 2008; 33: 133-138. (Pubitemid 351302196)
10. Bonini S, Mantelli F, Moretti C, Lambiase A, Bonini S, Micera A. Itchy-dry eye associated with polycystic ovary syndrome. Am J Ophthalmol 2007; 143: 763-771.
11. Coksuer H, Ozcura F, Oghan F, Haliloglu B, Karatas S. Effects of hyperandrogenism on tear function and tear drainage in patients with polycystic ovary syndrome. J Reprod Med 2011; 56: 65-70.
12. Lemp MA, Bron AJ, Baudouin C, Benarjez Del Castillo JM, Geffen D, Tauber J et al. Tear osmolarity in the diagnosis and management of dry eye disease. Am J Ophthalmol 2011; 151: 792-798.e1.
13. Versura P, Profazio V, Campos EC. Performance of tear osmolarity compared to previous diagnostic tests for dry eye diseases. Curr Eye Res 2010; 35: 553-564.
14. [No authors listed]. The defi nition and classifi cation of dry eye disease: report of the Defi nition and Classifi cation Subcommittee of the International Dry Eye WorkShop (2007). Ocul Surf. 2007; 5: 75-92.
15. Schiffman RM, Christianson MD, Jacobsen G, Hirsch JD, Reis BL. Reliability and validity of the Ocular Surface Disease Index. Arch Ophthalmol 2000; 118: 615-621. (Pubitemid 30327337)
16. Bron AJ, Evans VE, Smith JA. Grading of corneal and conjunctival staining in the context of other dry eye tests. Cornea 2003; 22: 640-650. (Pubitemid 37175145)
17. Nelson JD, Wright JC. Conjunctival goblet cell densities in ocular surface disease. Arch Ophthalmol 1984; 102: 1049-1051. (Pubitemid 14083489)
18. Apter D, Buzow T, Laughlin GA, Yen SS. Metabolic features of polycystic ovary syndrome are found in adolescent girls with hyperandrogenism. J Clin Endocrinol Metab 1995; 80: 2966-2973.
19. Nestler JE, Jakubowicz DJ. Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome. N Engl J Med 1996; 335: 617-623. (Pubitemid 26277951)
20. Sullivan DA, Rocha EM, Ullman MD, Krenzer KL, Gao J, Toda I et al. Androgen regulation of the meibomian gland. Adv Exp Med Biol 1998; 438: 327-331. (Pubitemid 28303756)
21. Sullivan DA, Krenzer KL, Sullivan BD, Tolls DB, Toda I, Dana MR. Does androgen insuffi ciency cause lacrimal gland infl ammation and aqueous tear defi ciency? Invest Ophthalmol Vis Sci 1999; 40: 1261-1265. (Pubitemid 29211466)
22. Sullivan DA, Wickham LA, Rocha EM, Krenzer KL, Sullivan BD, Steagall R et al. Androgens and dry eye in Sjren's syndrome. Ann N Y Acad Sci 1999; 876: 312-324. (Pubitemid 29352143)
23. Schaumberg DA, Buring JE, Sullivan DA, Dana MR. Hormone replacement therapy and dry eye syndrome. JAMA 2001; 286: 2114-2119. (Pubitemid 34041596)