Gene delivery of Homer1c rescues spatial learning in a rodent model of cognitive aging

Neurobiology of Aging

Volumn 34, Issue 8, 2013, Pages 1963-1970

  Gerstein, Hilary ^a,b   Lindstrom, Mary J ^a   Burger, Corinna ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Aged learning impaired; Cognitive aging; Gene rescue; Hippocampus; Homer; Morris water maze; Object location memory; Spatial learning

Indexed keywords

PARVOVIRUS VECTOR; PROTEIN HOMER 1C;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE; GENE EXPRESSION; HIPPOCAMPUS; HOMER1C GENE; LEARNING DISORDER; MALE; MAZE TEST; MORRIS WATER MAZE TEST; NONHUMAN; OBJECT LOCATION MEMORY TASK; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSYCHOLOGIC TEST; PSYCHOMOTOR PERFORMANCE; RAT; SPATIAL LEARNING; SPATIAL MEMORY; TASK PERFORMANCE; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY;

AGING; ANIMALS; CARRIER PROTEINS; DISEASE MODELS, ANIMAL; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; HIPPOCAMPUS; MALE; MAZE LEARNING; MEMORY DISORDERS; MICE; MOLECULAR TARGETED THERAPY; RATS; RATS, INBRED F344; RNA, MESSENGER; SPATIAL BEHAVIOR; UP-REGULATION;

EID: 84877596063     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2013.02.006     Document Type: Article

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