PFOS and PCB 153 have direct adverse effects on neonatal testis modeled using a coculture of primary gonocyte and sertoli cells

Environmental Toxicology

Volumn 28, Issue 6, 2013, Pages 322-331

  Zhang, Jie ^a,b   Liang, Jiren ^a,b   Zhu, Hongyan ^a,b   Li, Cuizhen ^a,b   Wu, Qing ^a,b  

^a FUDAN UNIVERSITY   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

Apoptosis; Coculture; Cytoskeleton; Exposure; Gonocyte; Neonatal; PCB 153; PFOS; ROS; Sertoli

Indexed keywords

COCULTURE; CYTOSKELETONS; EXPOSURE; GONOCYTE; NEONATAL; PCB 153; PFOS; ROS; SERTOLI;

ARGON LASERS; CELL DEATH; POLYCHLORINATED BIPHENYLS; PROTEINS; SELF ASSEMBLY;

ORGANIC POLLUTANTS;

2,2',4,4',5,5' HEXACHLOROBIPHENYL; ACTIN; PERFLUOROOCTANESULFONIC ACID; REACTIVE OXYGEN METABOLITE; VIMENTIN;

APOPTOSIS; BIOACCUMULATION; CELL ORGANELLE; CONCENTRATION (COMPOSITION); DOSE-RESPONSE RELATIONSHIP; HEALTH IMPACT; NEONATE; PCB; POLLUTION EFFECT; POLLUTION EXPOSURE; REPRODUCTIVE HEALTH; SULFONATE (ESTER);

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL VIABILITY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DOSE RESPONSE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SERTOLI CELL; TESTIS;

ALKANESULFONIC ACIDS; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; CELL SURVIVAL; COCULTURE TECHNIQUES; CYTOSKELETON; ENVIRONMENTAL POLLUTANTS; FLUOROCARBONS; GERM CELLS; MALE; POLYCHLORINATED BIPHENYLS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SERTOLI CELLS;

EID: 84877592204     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.20723     Document Type: Article

References (35)

1. Alam MS, Ohsako S, Tay TW, Tsunekawa N, Kanai Y, Kurohmaru M. 2010. Di(n-butyl) phthalate induces vimentin filaments disruption in rat sertoli cells: A possible relation with spermatogenic cell apoptosis. Anat Histol Embryol 39: 186-193.
2. Aumüller G, Schulze C, Viebahn C. 1992. Intermediate filaments in Sertoli cells. Microsc Res Tech 20: 50-72.
3. Ben-Ze'ev A, Robinson GS, Bucher NL, Farmer SR. 1988. Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes. Proc Natl Acad Sci USA 85: 2161-2165.
4. Bernal SD, Baylin SB, Shaper JH, Gazdar AF, Chen LB. 1983. Cytoskeleton associated proteins of human lung cancer cells. Cancer Res 43: 1798-1808.
5. Dickerson SM, Guevara E, Woller MJ, Gore AC. 2009. Cell death mechanisms in GT1-7 GnRH cells exposed to polychlorinated biphenyls PCB74, PCB118, and PCB153. Toxicol Appl Pharmacol 237: 237-245.
6. Furst P. 2006. Dioxins, polychlorinated biphenyls and other organohalogen compounds in human milk. Levels, correlations, trends and exposure through breastfeeding. Mol Nutr Food Res 50: 922-933.
7. Glynn AW, Wolk A, Aune M, Atuma S, Zettermark S, Maehle-Schmid M, Darnerud PO, Becker W, Vessby B, Adami HO. 2000. Serum concentrations of organochlorines in men: A search for markers of exposure. Sci Total Environ 263: 197-208.
8. Gregus Z, Klaassen CD. 2001. Mechanisms of toxicity. In: Klaassen CD, editor. Casarett and Doull's Toxicology: The Basic Science of Poisons, 6th ed. Beijing: McGraw-Hill. pp 61-64.
9. Hadley MA, Byers SW, Suárez-Quian CA, Kleinman HK, Dym M. 1985. Extracellular matrix regulates Sertoli cell differentiation, testicular cord formation, and germ cell development in vitro. J Cell Biol 101: 1511-1522.
10. Heineke J, Kempf T, Kraft T, Hilfiker A, Morawietz H, Scheubel RJ, Caroni P, Lohmann SM, Drexler H, Wollert KC. 2003. Downregulation of cytoskeletal muscle lim protein by nitric oxide. Impact on cardiac myocyte hypertrophy. Circulation 107: 1424-1432.
11. Hu XZ, Hu DC. 2009. Effects of perfluorooctanoate and perfluorooctane sulfonate exposure on hepatoma Hep G2 cells. Arch Toxicol 83: 851-861.
12. Irani K, Xia Y, Zweier JL, Sollott SJ, Der CJ, Fearon ER, Sundaresan M, Finkel T, Goldschimidt-Clermont PJ. 1997. Mitogenic signaling mediated by oxidants in Ras-trasformed fibroblasts. Science 275: 1649-1652.
13. Jégou B. 1993. The Sertoli-germ cell communication network in mammals. Int Rev Cytol 147: 25-96.
14. Jeon YJ, Youk ES, Lee SH, Suh J, Na YJ, Kim HM. 2002. Polychlorinated biphenyl-induced apoptosis of murine spleen cells is aryl hydrocarbon receptor independent but caspases dependent. Toxicol Appl Pharmacol 181: 116-123.
15. Joensen UN, Bossi R, Leffers H, Jensen AA, Skakkebaek NE, Jørgensen N. 2009. Do perfluoroalkyl compounds impair human semen quality? Environ Health Perspect 117: 923-927.
16. Kavlock RJ, Daston GP, DeRosa C, Fenner-Crisp P, Gray LE, Kaattari S, Lucier G, Luster M, Mac MJ, Maczka C, Miller R, Moore J, Rolland R, Scott G, Sheehan DM, Sinks T, Tilson HA. 1996. Research needs for the risk assessment of health and environmental effects of endocrine disruptors: A report of the US EPA-sponsored workshop. Environ Health Perspect 104( Suppl 4): 715-740.
17. Lau C, Anitole K, Hodes C, Lai D, Pfahles-Hutchens A, Seed J. 2007. Perfluoroalkyl acids: A review of monitoring and toxicological findings. Toxicol Sci 99: 366-394.
18. Lee DW, Gelein RM, Opanashuk LA. 2006. Heme-oxygenase-1 promotes polychlorinated biphenyl mixture aroclor 1254-induced oxidative stress and dopaminergic cell injury. Toxicol Sci 90: 159-167.
19. Lin CH, Lin PH. 2006. Induction of ROS formation, poly(ADP-ribose) polymerase-1 activation, and cell death by PCB126 and PCB153 in human T47D and MDA-MB-231 breast cancer cells. Chem Biol Interact 162: 181-194.
20. Li LH, Jester WFJr, Orth JM. 1998. Effects of relatively low levels of mono-(2-ethylhexyl) phthalate on cocultured Sertoli cells and gonocytes from neonatal rats. Toxicol Appl Pharmacol 153: 258-265.
21. Mariussen E, Myhre O, Reistad T, Fonnum F. 2002. The polychlorinated biphenyl mixture aroclor 1254 induces death of rat cerebellar granule cells: The involvement of the N-methyl-D-aspartate receptor and reactive oxygen species. Toxicol Appl Pharmacol 179: 137-144.
22. Olsen GW, Gilliland FD, Burlew MM, Burris JM, Mandel JS, Mandel JH. 1998. An epidemiologic investigation of reproductive hormones in men with occupational exposure to perfluorooctanoic acid. J Occup Environ Med 40: 614-622.
23. Orth JM. 1982. Proliferation of Sertoli cells in fetal and postnatal rats: A quantitative autoradiographic study. Anat Rec 203: 485-492.
24. Orth JM, Gunsalus GL, Lamperti AA. 1988. Evidence from Sertoli cell-depleted rats indicates that spermatid number in adults depends on numbers of Sertoli cells produced during perinatal development. Endocrinology 122: 787-794.
25. Oskam IC, Lyche JL, Krogenaes A, Thomassen R, Skaare JU, Wiger R, Dahl E, Sweeney T, Stien A, Ropstad E. 2005. Effects of long-term maternal exposure to low doses of PCB126 and PCB153 on the reproductive system and related hormones of young male goats. Reproduction 130: 731-742.
26. Ostertag SK, Tague BA, Humphries MM, Tittlemier SA, Chan HM. 2009. Estimated dietary exposure to fluorinated compounds from traditional foods among Inuit in Nunavut, Canada. Chemosphere 75: 1165-1172.
27. Qian Y, Ducatman A, Ward R, Leonard S, Bukowski V, Lan Guo N, Shi X, Vallyathan V, Castranova V. 2010. Perfluorooctane sulfonate (PFOS) induces reactive oxygen species (ROS) production in human microvascular endothelial cells: Role inendothelial permeability. J Toxicol Environ Health A 73: 819-836.
28. Raychoudhury SS, Flowers AF, Millette CF, Finlay MF. 2000. Toxic effects of polychlorinated biphenyls on cultured rat Sertoli cells. J Androl 21: 964-973.
29. Slotkin TA, MacKillop EA, Melnick RL, Thayer KA, Seidler FJ. 2008. Developmental neurotoxicity of perfluorinated chemicals modeled in vitro. Environ Health Perspect 116: 716-722.
30. Toppari J, Larsen JC, Christiansen P, Giwercman A, Grandjean P, Guillette LJJr, Jégou B, Jensen TK, Jouannet P, Keiding N, Leffers H, McLachlan JA, Meyer O, Müller J, Rajpert-De Meyts E, Scheike T, Sharpe R, Sumpter J, Skakkebaek NE. 1996. Male reproductive health and environmental xenoestrogens. Environ Health Perspect 104( Suppl 4): 741-803.
31. Trudel D, Horowitz L, Wormuth M, Scheringer M, Cousins IT, Hungerbühler K. 2008. Estimating consumer exposure to PFOS and PFOA. Risk Anal 28: 251-269.
32. Venkatesha VA, Venkataraman S, Sarsour EH, Kalen AL, Buettner GR, Robertson LW, Lehmler HJ, Goswami PC. 2008. Catalase ameliorates polychlorinated biphenyl-induced cytotoxicity in nonmalignant human breast epithelial cells. Free Radic Biol Med 45: 1094-1102.
33. Williams K, McKinnell C, Saunders PT, Walker M, Fisher JS, Turner KJ, Atanassova N, Sharpe M. 2001. Neonatal exposure to potent and environmental oestrogens and abnormalities of the male reproductive system in the rat: Evidence for importance of the androgen-oestrogen balance and assessment of the relevance to man. Hum Reprod Update 7: 236-247.
34. Xiao W, Li K, Wu Q, Nishimura N, Chang X, Zhou Z. 2010. Influence of persistent thyroxine reduction on spermatogenesis in rats neonatally exposed to 2, 2′, 4, 4′, 5, 5′-hexa-chlorobiphenyl. Birth Defects Res B Dev Reprod Toxicol 89: 18-25.
35. Zhao B, Hu GX, Chu Y, Jin X, Gong S, Akingbemi BT, Zhang Z, Zirkin BR, Ge RS. 2010. Inhibition of human and rat 3beta-hydroxysteroid dehydrogenase and 17beta-hydroxysteroid dehydrogenase 3 activities by perfluoroalkylated substances. Chem Biol Interact 188: 38-43.