A meta-analysis of mental health treatments and cardiac rehabilitation for improving clinical outcomes and depression among patients with coronary heart disease

Psychosomatic Medicine

Volumn 75, Issue 4, 2013, Pages 335-349

  Rutledge, Thomas ^a,b   Redwine, Laura S ^b   Linke, Sarah E ^b   Mills, Paul J ^b  

^a VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

cardiac rehabilitation; coronary heart disease; depression; mental health; meta analysis

Indexed keywords

ANTIDEPRESSANT AGENT;

CONFIDENCE INTERVAL; DEPRESSION; DISEASE SEVERITY; EFFECT SIZE; HEART REHABILITATION; HUMAN; ISCHEMIC HEART DISEASE; MENTAL HEALTH CARE; META ANALYSIS; MORTALITY; NUMBERS NEEDED TO TREAT; PRIORITY JOURNAL; PSYCHOTHERAPY; REVIEW; RISK REDUCTION; TREATMENT OUTCOME;

EID: 84877584896     PISSN: 00333174     EISSN: 15347796     Source Type: Journal    
DOI: 10.1097/PSY.0b013e318291d798     Document Type: Review

References (91)

1. Whooley MA, de Jonge P, Vittinghoff E, Otte C, Moos R, Carney RM, Ali S, Dowray S, Na B, FeldmanMD, Schiller NB, Browner WS. Depressive symptoms, health behaviors, and risk of cardiovascular events in patients with coronary heart disease. JAMA 2008; 300: 2379-88.
2. Meijer A, Conradi HJ, Bos EH, Thombs BD, van Melle JP, de Jonge P. Prognostic association of depression following myocardial infarction with mortality and cardiovascular events: a meta-analysis of 25 years of research. Gen Hosp Psychiatry 2011; 33: 203-16.
3. Davidson KW, Burg MM, Kronish IM, Shimbo D, Dettenborn L, Mehran R, Vorchheimer D, Clemow L, Schwartz JE, Lesperance F, Rieckmann N. Association of anhedonia with recurrent major adverse cardiac events and mortality 1 year after acute coronary syndrome. Arch Gen Psychiatry 2010; 67: 480-8.
4. van Melle JP, de Jonge P, Spijkerman TA, Tijssen JG, Ormel J, van Veldhuisen DJ, van den Brink RH, van den Berg MP. Prognostic association of depression following myocardial infarction with mortality and cardiovascular events: a meta-analysis. Psychosom Med 2004; 66: 814-22.
5. Glassman AH, O'Connor CM, Califf RM, Swedberg K, Schwartz P, Bigger JT Jr, Krishnan KR, van Zyl LT, Swenson JR, Finkel MS, Landau C, Shapiro PA, Pepine CJ,Mardekian J, HarrisonWM, Barton D,McLvor M. Sertraline treatment of major depression in patients with acute MI or unstable angina. JAMA 2002; 288: 701-9.
6. Lesperance F, Frasure-Smith N, Koszycki D, Laliberte MA, van Zyl LT, Baker B, Swenson JR, Ghatavi K, Abramson BL, Dorian P, Guertin MC. Effects of citalopram and interpersonal psychotherapy on depression in patients with coronary artery disease: the Canadian Cardiac Randomized Evaluation of Antidepressant and Psychotherapy Efficacy (CREATE) trial. JAMA 2007; 297: 367-79.
7. Berkman LF, Blumenthal J, Burg M, Carney RM, Catellier D, Cowan MJ, Czajkowski SM, DeBusk R, Hosking J, Jaffe A, Kaufmann PG, Mitchell P, Norman J, Powell LH, Raczynski JM, Schneiderman N. Effects of treating depression and low perceived social support on clinical events after myocardial infarction: the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) randomized trial. JAMA 2003; 289: 3106-16.
8. Frasure-Smith N, Lesperance F, Prince RH, Verrier P, Garber RA, Juneau M, Wolfson C, Bourassa MG. Randomised trial of home-based psychological nursing intervention for patients recovering from myocardial infarction. Lancet 1997; 350: 473-9.
9. Jones DA, West RR. Psychological rehabilitation after myocardial infarction: multicentre randomised controlled trial. BMJ 1996; 313: 1517-21.
10. Gulliksson M, Burell G, Vessby B, Lundin L, Toss H, Svardsudd K. Randomized controlled trial of cognitive behavioral therapy vs standard treatment to prevent recurrent cardiovascular events in patients with coronary heart disease: Secondary Prevention in Uppsala Primary Health Care project (SUPRIM). Arch Intern Med 2011; 171: 134-40.
11. Baumeister H, Hutter N, Bengel J. Psychological and pharmacological interventions for depression in patients with coronary artery disease. Cochrane Database Syst Rev 2011; 7; 9: CD008012.
12. Whalley B, Rees K, Davies P, Bennett P, Ebrahim S, Liu Z, West R, Moxham T, Thompson DR, Taylor RS. Psychological interventions for coronary heart disease. Cochrane Database Syst Rev 2011; 8: CD002902.
13. Pizzi C, Rutjes AW, Costa GM, Fontana F, Mezzetti A, Manzoli L. Metaanalysis of selective serotonin reuptake inhibitors in patients with depression and coronary heart disease. Am J Cardiol 2011; 107: 972-9.
14. Lawler PR, Filion KB, Eisenberg MJ. Efficacy of exercise-based cardiac rehabilitation postYmyocardial infarction: a systematic review and metaanalysis of randomized controlled trials. Am Heart J 2011; 162: 571-584.e2.
15. Clark AM, Hartling L, Vandermeer B, McAlister FA. Meta-analysis: secondary prevention programs for patients with coronary artery disease. Ann Intern Med 2005; 143: 659-72.
16. Blumenthal JA, Babyak MA, O'Connor C, Keteyian S, Landzberg J, Howlett J, Kraus W, Gottlieb S, Blackburn G, Swank A, Whellan DJ. Effects of exercise training on depressive symptoms in patients with chronic heart failure. JAMA 2012; 308: 465-74.
17. Higgins JPT, Altman DG, Sterne JAC, editors. Assessing risk of bias in included studies. In: Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration; 2011.
18. Linden W, Phillips MJ, Leclerc J. Psychological treatment of cardiac patients: a meta-analysis. Eur Heart J 2007; 28: 2972-84.
19. Dusseldorp E, van Elderen T, Maes S, Meulman J, Kraaij V. A metaanalysis of psychoeduational programs for coronary heart disease patients. Health Psychol 1999; 18: 506-19.
20. Blumenthal JA, Jiang W, Babyak MA, Krantz DS, Frid DJ, Coleman RE, Waugh R, Hanson M, Appelbaum M, O'Connor C, Morris JJ. Stress management and exercise training in cardiac patients with myocardial ischemia. Effects on prognosis and evaluation of mechanisms. Arch Intern Med 1997; 157: 2213-23.
21. Strik JJ, Honig A, Lousberg R, Lousberg AH, Cheriex EC, Tuynman-Qua HG, Kuijpers PM, Wellens HJ, Van Praag HM. Efficacy and safety of fluoxetine in the treatment of patients with major depression after first myocardial infarction: findings from a double-blind, placebo controlled trial. Psychosom Med 2000; 62: 783-9.
22. Cowan MJ, Pike KC, Budzynski HK. Psychosocial nursing therapy following sudden cardiac arrest: impact on two-year survival. Nurs Res 2001; 50: 68-76.
23. Appels A, Bar F, van der Pol G, Erdman R, Assman M, Trijsburg W, van Diest R, van Dixhoorn J, Mendes de Leon C. Effects of treating exhaustion in angioplasty patients on new coronary events: results of the randomized Exhaustion Intervention Trial (EXIT). Psychosom Med 2005; 67: 217-23.
24. Claesson M, Birgander LS, Lindahl B, Nasic S, Astrom M, Asplund K, Burell G. Women's heartsYstress management for women with ischemic heart disease: explanatory analyses of a randomized controlled trial. J Cardiopulm Rehabil 2005; 25: 93-102.
25. Michalsen A, Grossman P, Lehmann N, Knoblauch NT, Paul A, Moebus S, Budde T, Dobos GJ. Psychological and quality-of-life outcomes from a comprehensive stress reduction and lifestyle program in patients with coronary artery disease: results of a randomized trial. Psychother Psychosom 2005; 74: 344-52.
26. Sebregts EH, Falger PR, Appels A, Kester AD, Bar FW. Psychological effects of a short behavior modification program in patients with acute myocardial infarction or coronary artery bypass grafting. A randomized controlled trial. J Psychosom Res 2005; 58: 417-24.
27. Gottlieb SS, Kop WJ, Thomas SA, Katzen S, Vesely MR, Greenberg N, Marshall J, Cines M, Minshall S. A double-blind placebo controlled pilot study of controlled-release paroxetine on depression and quality of life in chronic heart failure. Am Heart J 2007; 153: 868-73.
28. van Melle JP, de Jonge P, Honig A, Schene AH, Kuyper AM, Crijns HJ, Schins A, Tulner D, van den Berg MP, Ormel J. Effects of antidepressant treatment following myocardial infarction. Br J Psychiatry 2007; 190: 460-6.
29. Koertge J, Janszky I, Sundin O, Blom M, Georgiades A, Laszlo KD, Alinaghizadeh H, Ahnve S. Effects of a stress management program on vital exhaustion and depression in women with coronary heart disease: a randomized controlled intervention study. J Intern Med 2008; 263: 281-93.
30. Davidson KW, Rieckmann N, Clemow L, Schwartz JE, Shimbo D, Medina V, Albanese G, Kronish I, Hegel M, Burg MM. Enhanced depression care for patients with acute coronary syndrome and persistent depressive symptoms: coronary psychosocial evaluation studies randomized controlled trial. Arch Intern Med 2010; 170: 600-8.
31. O'Connor CM, Jiang W, Kuchibhatla M, Silva SG, Cuffe MS, Callwood DD, Zakhary B, Stough WG, Arias RM, Rivelli SK, Krishnan R; SADHART-CHF Investigators. Safety and efficacy of sertraline for depression in patients with heart failure: results of the SADHART-CHF (Sertraline Against Depression and Heart Disease in Chronic Heart Failure) trial. J Am Coll Cardiol 2010; 56: 692-9.
32. Specchia G, De Servi S, Scire A, Assandri J, Berzuini C, Angoli L, La Rovere MT, Cobelli F. Interaction between exercise training and ejection fraction in predicting prognosis after a first myocardial infarction. Circulation 1996; 94: 978-82.
33. Giannuzzi P, Temporelli PL, Corra U, Gattone M, Giordano A, Tavazzi L. Attenuation of unfavorable remodeling by exercise training in postinfarction patients with left ventricular dysfunction: results of the Exercise in Left Ventricular Dysfunction (ELVD) trial. Circulation 1997; 96: 1790-7.
34. Ornish D, Scherwitz LW, Billings JH, Brown SE, Gould KL, Merritt TA, Sparler S, Armstrong WT, Ports TA, Kirkeeide RL, Hogeboom C, Brand RJ. Intensive lifestyle changes for reversal of coronary heart disease. JAMA 1998; 280: 2001-7.
35. Dugmore LD, Tipson RJ, Phillips MH, Flint EJ, Stentiford NH, Bone MF, Littler WA. Changes in cardiorespiratory fitness, psychological wellbeing, quality of life, and vocational status following a 12 month cardiac exercise rehabilitation programme. Heart 1999; 81: 359-66.
36. Lisspers J, Sundin O, Hofman-Bang C, Nordlander R, Nygren A, Ryden L, Ohman A. Behavioral effects of a comprehensive, multifactorial program for lifestyle change after percutaneous transluminal coronary angioplasty: a prospective, randomized controlled study. J PsychosomRes 1999; 46: 143-54.
37. Heldal M, Sire S, Dale J. Randomised training after myocardial infarction: short and long-term effects of exercise training after myocardial infarction in patients on beta-blocker treatment. A randomized, controlled study. Scand Cardiovasc J 2000; 34: 59-64
38. Myers J, Goebbels U, Dzeikan G, Froelicher V, Bremerich J, Mueller P, Buser P, Dubach P. Exercise training and myocardial remodeling in patients with reduced ventricular function: one-year follow-up with magnetic resonance imaging. Am Heart J 2000; 139: 252-61.
39. Naughton J, Dorn J, Oberman A, Gorman PA, Cleary P. Maximal exercise systolic pressure, exercise training, and mortality in myocardial infarction patients. Am J Cardiol 2000; 85: 416-20.
40. Belardinelli R, Paolini I, Cianci G, Piva R, Georgiou D, Purcaro A. Exercise training intervention after coronary angioplasty: the ETICA trial. J Am Coll Cardiol 2001; 37: 1891-900.
41. La Rovere MT, Bersano C, Gnemmi M, Specchia G, Schwartz PJ. Exerciseinduced increase in baroreflex sensitivity predicts improved prognosis after myocardial infarction. Circulation 2002; 106: 945-9.
42. Marchionni N, Fattirolli F, Fumagalli S, Oldridge N, Del Lungo F, Morosi L, Burgisser C, Masotti G. Improved exercise tolerance and quality of life with cardiac rehabilitation of older patients after myocardial infarction: results of a randomized, controlled trial. Circulation 2003; 107: 2201-6.
43. Vestfold Heartcare Study Group. Influence on lifestyle measures and fiveyear coronary risk by a comprehensive lifestyle intervention programme in patients with coronary heart disease. Eur J Cardiovasc Prev Rehabil 2003; 10: 429-37.
44. Yu CM, Lau CP, Chau J, McGhee S, Kong SL, Cheung BM, Li LS. A short course of cardiac rehabilitation program is highly cost effective in improving long-term quality of life in patients with recent myocardial infarction or percutaneous coronary intervention. Arch Phys Med Rehabil 2004; 85: 1915-22.
45. Giallauria F, Lucci R, De Lorenzo A, D'Agostino M, Del Forno D, Vigorito C. Favourable effects of exercise training on N-terminal proYbrain natriuretic peptide plasma levels in elderly patients after acute myocardial infarction. Age Ageing 2006; 35: 601-7.
46. Zwisler AD, Soja AM, Rasmussen S, Frederiksen M, Abedini S, Appel J, Rasmussen H, Gluud C, Iversen L, Sigurd B, Madsen M, Fischer-Hansen J; DANREHAB Group. Hospital-based comprehensive cardiac rehabilitation versus usual care among patients with congestive heart failure, ischemic heart disease, or high risk of ischemic heart disease: 12-month results of a randomized clinical trial. Am Heart J 2008; 155: 1106-13.
47. Giannuzzi P, Temporelli PL, Marchioli R, Maggioni AP, Balestroni G, Ceci V, Chieffo C, Gattone M, Griffo R, Schweiger C, Tavazzi L, Urbinati S, Valagussa F, Vanuzzo D; GOSPEL Investigators. Global secondary prevention strategies to limit event recurrence aftermyocardial infarction: results of the GOSPEL study, a multicenter, randomized controlled trial from the Italian Cardiac Rehabilitation Network. Arch Intern Med 2008; 168: 2194-204.
48. Lee BC, Hsu HC, Tseng WY, Su MY, Chen SY, Wu YW, Chien KL, Chen MF. Effect of cardiac rehabilitation on angiogenic cytokines in postinfarction patients. Heart 2009; 95: 1012-8.
49. Davidson PM, Cockburn J, Newton PJ,Webster JK, Betihavas V, Howes L, Owensby DO. Can a heart failureYspecific cardiac rehabilitation program decrease hospitalizations and improve outcomes in high-risk patients? Eur J Cardiovasc Prev Rehabil 2010; 17: 393-402.
50. McFarlane A, Kamath MV, Fallen EL, Malcolm V, Cherian F, Norman G. Effect of sertraline on the recovery rate of cardiac autonomic function in depressed patients after acute myocardial infarction. Am Heart J 2001; 142: 617-23.
51. Sundin O, Lisspers J, Hofman-Bang C, Nygren A, Ryden L, Ohman A. Comparing multifactorial lifestyle interventions and stress management in coronary risk reduction. Int J Behav Med 2003; 10: 191-204.
52. Bishop GD, Kaur D, Tan VL, Chua YL, Liew SM, Mak KH. Effects of a psychosocial skills training workshop on psychophysiological and psychosocial risk in patients undergoing coronary artery bypass grafting. Am Heart J 2005; 150: 602-9.
53. Blumenthal JA, Sherwood A, Babyak MA, Watkins LL, Waugh R, Georgiades A, Bacon SL, Hayano J, Coleman RE, Hinderliter A. Effects of exercise and stress management training on markers of cardiovascular risk in patients with ischemic heart disease: a randomized controlled trial. JAMA 2005; 293: 1626-34.
54. Fraguas R, da Silva Telles RM, Alves TC, Andrei AM, Rays J, Iosifescu DV, Wajngarten M. A double-blind, placebo-controlled treatment trial of citalopram for major depressive disorder in older patients with heart failure: the relevance of the placebo effect and psychological symptoms. Contemp Clin Trials 2009; 30: 205-11.
55. Freedland KE, Skala JA, Carney RM, Rubin EH, Lustman PJ, Davila-Roman VG, Steinmeyer BC, Hogue CW Jr. Treatment of depression after coronary artery bypass surgery: a randomized controlled trial. Arch Gen Psychiatry 2009; 66: 387-96.
56. Pizzi C, Mancini S, Angeloni L, Fontana F, Manzoli L, Costa GM. Effects of selective serotonin reuptake inhibitor therapy on endothelial function and inflammatory markers in patients with coronary heart disease. Clin Pharmacol Ther 2009; 86: 527-32.
57. Gary RA, Dunbar SB, Higgins MK, Musselman DL, Smith AL. Combined exercise and cognitive behavioral therapy improves outcomes in patients with heart failure. J Psychosom Res 2010; 69: 119-31.
58. Oldridge N, Perkins A, Marchionni N, Fumagalli S, Fattirolli F, Guyatt G. Number needed to treat in cardiac rehabilitation. J Cardiopulm Rehabil 2002; 22: 22-30.
59. Hedges LV, Olkin I. Statistical Methods for Meta-Analysis. San Diego: Academic Press; 1985.
60. Wallace BC, Schmid CH, Lau J, Trikalinos TA. Meta-Analyst: software for meta-analysis of binary, continuous and diagnostic data. BMC Med Res Methodol 2009; 9: 80.
61. Hofman-Bang C, Lisspers J, Nordlander R, Nygren A, Sundin O, Ohman A, Ryden L. Two-year results of a controlled study of residential rehabilitation for patients treated with percutaneous transluminal coronary angioplasty. A randomized study of a multifactorial programme. Eur Heart J 1999; 20: 1465-74.
62. Seki E,Watanabe Y, Sunayama S, Iwama Y, Shimada K, Kawakami K, Sato M, Sato H, Mokuno H, Daida H. Effects of phase III cardiac rehabilitation programs on health-related quality of life in elderly patients with coronary artery disease: Juntendo Cardiac Rehabilitation Program (J-CARP). Circ J 2003; 67: 73-7.
63. Bettencourt N, Dias C, Mateus P, Sampaio F, Santos L, Adao L, Mateus C, Salome N, Miranda F, Teixeira M, Simoes L, Ribeiro VG. Impact of cardiac rehabilitation on quality of life and depression after acute coronary syndrome. Rev Port Cardiol 2005; 24: 687-96.
64. Reid RD, Dafoe WA, Morrin L, Mayhew A, Papadakis S, Beaton L, Oldridge NB, Coyle D, Wells GA. Impact of program duration and contact frequency on efficacy and cost of cardiac rehabilitation: results of a randomized trial. Am Heart J 2005; 149: 862-8.
65. Scholz U, Knoll N, Sniehotta FF, Schwarzer R. Physical activity and depressive symptoms in cardiac rehabilitation: long-term effects of a selfmanagement intervention. Soc Sci Med 2006; 62: 3109-20.
66. Kulcu DG, Kurtais Y, Tur BS, Gu lec S, Seckin B. The effect of cardiac rehabilitation on quality of life, anxiety and depression in patients with congestive heart failure. A randomized controlled trial, short-term results. Eura Medicophys 2007; 43: 489-97.
67. Beckie TM, Beckstead JW, Schocken DD, Evans ME, Fletcher GF. The effects of a tailored cardiac rehabilitation program on depressive symptoms in women: a randomized clinical trial. Int J Nurs Stud 2011; 48: 3-12.
68. European Association of Cardiovascular Prevention and Rehabilitation Committee for Science Guidelines; EACPR, Corra U, Piepoli MF, Carre F, Heuschmann P, Hoffmann U, Verschuren M, Halcox J; Document Reviewers, Giannuzzi P, Saner H, Wood D, Piepoli MF, Corra U, Benzer W, Bjarnason-Wehrens B, Dendale P, Gaita D, McGee H, Mendes M, Niebauer J, Zwisler AD, Schmid JP. Secondary prevention through cardiac rehabilitation: physical activity counselling and exercise training: key components of the position paper from the Cardiac Rehabilitation Section of the European Association of Cardiovascular Prevention and Rehabilitation. Eur Heart J 2010; 31: 1967-74.
69. Serruys PW, Morice MC, Kappetein AP, Colombo A, Holmes DR, Mack MJ, Sta?hle E, Feldman TE, van den Brand M, Bass EJ, Van Dyck N, Leadley K, Dawkins KD, Mohr FW; SYNTAX Investigators. Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease. N Engl J Med 2009; 360: 961-72.
70. Lavie CJ, Milani RV, Cassidy MM, Gilliland YE. Effects of cardiac rehabilitation and exercise training programs in women with depression. Am J Cardiol 1999; 83: 1480-3, A7.
71. Milani RV, Lavie CJ, Mehra MR, Ventura HO. Impact of exercise training and depression on survival in heart failure due to coronary heart disease. Am J Cardiol 2011; 107: 64-8.
72. Milani RV, Lavie CJ. Impact of cardiac rehabilitation on depression and its associated mortality. Am J Med 2007; 120: 799-806.
73. Blumenthal JA, Babyak MA, Carney RM, Huber M, Saab PG, Burg MM, Sheps D, Powell L, Taylor CB, Kaufmann PG. Exercise, depression, and mortality after myocardial infarction in the ENRICHD trial. Med Sci Sports Exerc 2004; 36: 746-55.
74. Dusseldorp E, van Elderen T, Maes S, Meulman J, Kraaij V. A meta-analysis of psychoeducational programs for coronary heart disease patients. Health Psychol 1999; 18: 506-19.
75. Carney RM, Blumenthal JA, Freedland KE, Youngblood M, Veith RC, Burg MM, Cornell C, Saab PG, Kaufmann PG, Czajkowski SM, Jaffe AS; ENRICHD Investigators. Depression and late mortality after myocardial infarction in the Enhancing Recovery in Coronary Heart Disease (ENRICHD) study. Psychosom Med 2004; 66: 466-74.
76. Cossette S, Frasure-Smith N, Lesperance F. Clinical implications of a reduction in psychological distress on cardiac prognosis in patients participating in a psychosocial intervention program. Psychosom Med 2001; 63: 257-66.
77. Daley A. Exercise and depression: review of reviews. J Clin Psychol Med Settings 2008; 15: 140-7.
78. Blumenthal JA, Babyak MA, Doraiswamy PM, Watkins L, Hoffman BM, Barbour KA, Herman S, Craighead WE, Brosse AL,Waugh R, Hinderliter A, Sherwood A. Exercise and pharmacotherapy in the treatment of major depressive disorder. Psychosom Med 2007; 69: 587-96.
79. Mead GE, Morley W, Campbell P, Greig CA, McMurdo M, Lawlor DA. Exercise for depression. Cochrane Database Syst Rev 2009; 3: CD004366.
80. Raedler TJ. Inflammatory mechanisms in major depressive disorder. Curr Opin Psychiatry 2011; 24: 519-25.
81. Hughes JW, Casey E, Doe VH, Glickman EL, Stein PK, Waechter D, Josephson R, Rosneck J. Depression and heart rate variability in cardiac rehabilitation patients: exploring the roles of physical activity and fitness. Percept Mot Skills 2010; 111: 608-24.
82. Kemp AH, Quintana DS, Gray MA, Felmingham KL, Brown K, Gatt JM. Impact of depression and antidepressant treatment on heart rate variability: a review and meta-analysis. Biol Psychiatry 2010; 67: 1067-74.
83. Curtis BM, O'Keefe JH Jr. Autonomic tone as a cardiovascular risk factor: the dangers of chronic fight or flight. Mayo Clin Proc 2002; 77: 45-54.
84. Thayer JF, Sternberg E. Beyond heart rate variability: vagal regulation of allostatic systems. Ann N Y Acad Sci 2006; 1088: 361-72.
85. Edwards KM, Ziegler MG, Mills PJ. The potential anti-inflammatory benefits of improving physical fitness in hypertension. J Hypertens 2007; 25: 1533-42.
86. Leon AS, Franklin BA, Costa F, Balady GJ, Berra KA, Stewart KJ, Thompson PD, Williams MA, Lauer MS; American Heart Association; Council on Clinical Cardiology (Subcommittee on Exercise, Cardiac Rehabilitation, and Prevention); Council on Nutrition, Physical Activity, and Metabolism (Subcommittee on Physical Activity); American association of Cardiovascular and Pulmonary Rehabilitation. Cardiac rehabilitation and secondary prevention of coronary heart disease: an American Heart Association scientific statement from the Council on Clinical Cardiology (Subcommittee on Exercise, Cardiac Rehabilitation, and Prevention) and the Council on Nutrition, Physical Activity, and Metabolism (Subcommittee on Physical Activity), in collaboration with the American association of Cardiovascular and Pulmonary Rehabilitation. Circulation 2005; 111: 369-76.
87. Jackson L, Leclerc J, Erskine Y, Linden W. Getting the most out of cardiac rehabilitation a review of referral and adherence predictors. Heart 2005; 91: 10-4.
88. Beswick AD, Rees K,West RR, Taylor FC, Burke M, Griebsch I, Taylor RS, Victory J, Brown J, Ebrahim S. Improving uptake and adherence in cardiac rehabilitation: literature review. J Adv Nurs 2005; 49: 538-55.
89. Caulin-Glaser T, Maciejewski PK, Snow R, LaLonde M, Mazure C. Depressive symptoms and sex affect completion rates and clinical outcomes in cardiac rehabilitation. Prev Cardiol 2007; 10: 15-21.
90. McGrady A, McGinnis R, Badenhop D, Bentle M, Rajput M. Effects of depression and anxiety on adherence to cardiac rehabilitation. J Cardiopulm Rehabil Prev 2009; 29: 358-64.
91. SwardfagerW, Herrmann N, Marzolini S, Saleem M, Farber SB, Kiss A, Oh PI, Lanctot KL. Major depressive disorder predicts completion, adherence, and outcomes in cardiac rehabilitation: a prospective cohort study of 195 patients with coronary artery disease. J Clin Psychiatry 2011; 72: 1181-8.