Emergency department vancomycin use: Dosing practices and associated outcomes

Journal of Emergency Medicine

Volumn 44, Issue 5, 2013, Pages 910-918

  Fuller, Brian M ^a   Mohr, Nicholas ^b   Skrupky, Lee ^c   Mueller, Kristen ^a   McCammon, Craig ^c  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c BARNES JEWISH HOSPITAL   (United States)

Author keywords

dosing; Emergency Department; outcomes; vancomycin

Indexed keywords

AZTREONAM; CEFEPIME; CEFTRIAXONE; CIPROFLOXACIN; GENTAMICIN; MEROPENEM; MOXIFLOXACIN; PIPERACILLIN PLUS TAZOBACTAM; VANCOMYCIN;

ADULT; AGED; ARTICLE; BODY WEIGHT; CLINICAL PRACTICE; DRUG DOSE REGIMEN; DRUG EFFECT; DRUG OVERDOSE; DRUG UNDERDOSE; DRUG USE; EMERGENCY WARD; FEMALE; GRAM NEGATIVE INFECTION; HOSPITALIZATION; HUMAN; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; TERTIARY HEALTH CARE;

ACADEMIC MEDICAL CENTERS; ADULT; AGED; ANTI-BACTERIAL AGENTS; BODY WEIGHT; COHORT STUDIES; CREATININE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG UTILIZATION; EMERGENCY SERVICE, HOSPITAL; FEMALE; HOSPITAL MORTALITY; HUMANS; LENGTH OF STAY; LOGISTIC MODELS; MALE; MEDICATION ERRORS; MIDDLE AGED; RETROSPECTIVE STUDIES; VANCOMYCIN;

EID: 84877582648     PISSN: 07364679     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jemermed.2012.09.036     Document Type: Article

References (37)

1. S.R. Norrby, C.E. Nord, R. Finch European Society of Clinical Microbiology and Infectious Diseases Lack of development of new antimicrobial drugs: a potential serious threat to public health Lancet Infect Dis 5 2005 115 119
2. C.C. Achiam, C.M. Fernandes, and S.L. McLeod Methicillin-resistant Staphylococcus aureus in skin and soft tissue infections presenting to the Emergency Department of a Canadian Academic Health Care Center Eur J Emerg Med 18 2012 2 8
3. L. May, K. Harter, and K. Yadav Practice patterns and management strategies for purulent skin and soft-tissue infections in an urban academic ED Am J Emerg Med 30 2012 302 310
4. C.A. Odell Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) skin infections Curr Opin Pediatr 22 2010 273 277
5. D.J. Pallin, D.J. Egan, A.J. Pelletier, J.A. Espinola, D.C. Hooper, and C.A. Camargo Jr. Increased US emergency department visits for skin and soft tissue infections, and changes in antibiotic choices, during the emergence of community-associated methicillin-resistant Staphylococcus aureus Ann Emerg Med 51 2008 291 298
6. F. Alvarez-Lerma Modification of empiric antibiotic treatment in patients with pneumonia acquired in the intensive care unit Intensive Care Med 22 1996 387 394
7. E.H. Ibrahim, G. Sherman, S. Ward, V.J. Fraser, and M.H. Kollef The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting Chest 118 2000 146 155
8. M.H. Kollef Inadequate antimicrobial treatment: an important determinant of outcome for hospitalized patients Clin Infect Dis 31 Suppl 4 2000 S131 S138
9. A. Kumar, D. Roberts, and K.E. Wood Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock Crit Care Med 34 2006 1589 1596
10. L. Leibovici, I. Shraga, M. Drucker, H. Konigsberger, Z. Samra, and S. Pitlik The benefit of appropriate empirical antibiotic treatment in patients with bloodstream infection J Intern Med 244 1998 379 386
11. T.P. Lodise, P.S. McKinnon, L. Swiderski, and M.J. Rybak Outcomes analysis of delayed antibiotic treatment for hospital-acquired Staphylococcus aureus bacteremia Clin Infect Dis 36 2003 1418 1423
12. E.W. Mueller, S.D. Hanes, M.A. Croce, G.C. Wood, B.A. Boucher, and T.C. Fabian Effect from multiple episodes of inadequate empiric antibiotic therapy for ventilator-associated pneumonia on morbidity and mortality among critically ill trauma patients J Trauma 58 2005 94 101
13. M.J. Rybak, B.M. Lomaestro, and J.C. Rotschafer Vancomycin therapeutic guidelines: a summary of consensus recommendations from the infectious diseases Society of America, the American Society of Health-System Pharmacists, and the Society of Infectious Diseases Pharmacists Clin Infect Dis 49 2009 325 327
14. S. Wright Appropriateness of vancomycin use in the emergency department Ann Emerg Med 32 1998 531 536
15. L. Hidayat High dose vancomycin therapy for MRSA infections efficacy and toxicity Arch Intern Med 166 2006 2138 2144
16. M.N. Jeffres, W. Isakow, and J.A. Doherty Predictors of mortality for methicillin-resistant Staphylococcus aureus health-care-associated pneumonia: specific evaluation of vancomycin pharmacokinetic indices Chest 130 2006 947 955
17. E. Rivers, B. Nguyen, S. Havstad Early Goal-Directed Therapy Collaborative Group Early goal-directed therapy in the treatment of severe sepsis and septic shock N Engl J Med 345 2001 1368 1377
18. M. Duong, S. Markwell, J. Peter, and S. Barenkamp Randomized, controlled trial of antibiotics in the management of community-acquired skin abscesses in the pediatric patient Ann Emerg Med 55 2010 401 407
19. G. Moran Methicillin-resistant S. aureus infections among patients in the emergency department N Engl J Med 355 2006 666 674
20. J.L. Llera, and R.C. Levy Treatment of cutaneous abscess: a double-blind clinical study Ann Emerg Med 14 1985 15 19
21. P.M. Rajendran, D. Young, and T. Maurer Randomized, double-blind, placebo-controlled trial of cephalexin for treatment of uncomplicated skin abscesses in a population at risk for community-acquired methicillin-resistant Staphylococcus aureus infection Antimicrob Agents Chemother 51 2007 4044 4048
22. M.C. Lee, A.M. Rios, and M.F. Aten Management and outcome of children with skin and soft tissue abscesses caused by community-acquired methicillin-resistant Staphylococcus aureus Pediatr Infect Dis J 23 2004 123 127
23. M.B. Hasty, A. Klasner, and S. Kness Cutaneous community-associated methicillin-resistant Staphylococcus aureus among all skin and soft-tissue infections in two geographically distant pediatric emergency departments Acad Emerg Med 14 2007 35 40
24. A.E. Patanwala, C.J. Norris, D.E. Nix, B.J. Kopp, and B.L. Erstad Vancomycin dosing for pneumonia in critically ill trauma patients J Trauma 67 2009 802 804
25. T.P. Lodise, N. Patel, B.M. Lomaestro, K.A. Rodvold, and G.L. Drusano Relationship between initial vancomycin concentration-time profile and nephrotoxicity among hospitalized patients Clin Infect Dis 49 2009 507 514
26. K.A. Hazlewood, S.D. Brouse, W.D. Pitcher, and R.G. Hall Vancomycin-associated nephrotoxicity: grave concern or death by character assassination? Am J Med 123 2010 182.e1 182.e7
27. A. Wong-Beringer, J. Joo, E. Tse, and P. Beringer Vancomycin-associated nephrotoxicity: a critical appraisal of risk with high-dose therapy Int J Antimicrob Agents 37 2011 95 101
28. C. Pollack Jr. , and E. Braunwald Update to the ACC/AHA guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction: implications for emergency department practice Ann Emerg Med 51 2008 591 606
29. Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group N Engl J Med 333 1995 1581 1587
30. A. Kumar, D. Roberts, and K. Wood Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock Crit Care Med 34 2006 1589 1596
31. K. Wood Major pulmonary embolism: review of a pathophysiologic approach to the golden hour of hemodynamically significant pulmonary embolsim Chest 121 2002 877 905
32. E. Boersma, A. Maas, and J.W. Deckers Early thrombolytic treatment in acute myocardial infarction: reappraisal of the golden hour Lancet Infect Dis 348 1996 771 775
33. O. Blow, L. Magliore, and J. Claridge The golden hour and the silver day: detection and correction of occult hypoperfusion within 24 hours improves outcomes from major trauma J Trauma 47 1999 964 969
34. D.C. Angus, W.T. Linde-Zwirble, J. Lidicker, G. Clermont, J. Carcillo, and M.R. Pinsky Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care Crit Care Med 29 2001 1303 1310
35. J.S. Solomkin, J.E. Mazuski, and J.S. Bradley Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection Society and the Infectious Diseases Society of America Surg Infect (Larchmt) 11 2010 79 109
36. R. Daza, J. Gutiérrez, and G. Piédrola Antibiotic susceptibility of bacterial strains isolated from patients with community-acquired urinary tract infections Int J Antimicrob Agents 18 2001 211 215
37. R.R. Muder, C. Brennen, and J.D. Rihs Isolation of Staphylococcus aureus from the urinary tract: association of isolation with symptomatic urinary tract infection and subsequent staphylococcal bacteremia Clin Infect Dis 42 2006 46 50