Insulin resistance impairs cutaneous wound healing in mice

Wound Repair and Regeneration

Volumn 21, Issue 3, 2013, Pages 464-472

  Otranto, Marcela ^a   Nascimento, Adriana Paulino Do ^a   Monte Alto Costa, Andréa ^a  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CHOLESTEROL; COLLAGEN FIBER; GLUCOSE; HYDROXYPROLINE; INDUCIBLE NITRIC OXIDE SYNTHASE; TRANSFORMING GROWTH FACTOR BETA; TRIACYLGLYCEROL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY MASS; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DEBRIDEMENT; FULL THICKNESS SKIN GRAFT; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; INFLAMMATORY INFILTRATE; INSULIN RESISTANCE; INSULIN TOLERANCE TEST; LIPID DIET; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; SKIN INJURY; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN; WOUND HEALING;

ANIMALS; DISEASE MODELS, ANIMAL; FOLLOW-UP STUDIES; GLUCOSE TOLERANCE TEST; HYDROXYPROLINE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INSULIN RESISTANCE; MALE; MICE; MICE, INBRED C57BL; NITRIC OXIDE SYNTHASE TYPE II; SKIN; WOUND HEALING; WOUNDS AND INJURIES;

EID: 84877581912     PISSN: 10671927     EISSN: 1524475X     Source Type: Journal    
DOI: 10.1111/wrr.12042     Document Type: Article

References (30)

1. Zeyda M, Stulnig TM,. Obesity, inflammation, and insulin resistance-a mini-review. Gerontology 2009; 55: 379-386.
2. Cheung KP, Taylor KR, Jameson JM,. Immunomodulation at epithelial sites by obesity and metabolic disease. Immunol Res 2012; 52: 182-199.
3. Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW, Jr,. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003; 112: 1796-1808.
4. Lumeng CN, Deyoung SM, Bodzin JL, Saltiel AR,. Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity. Diabetes 2007; 56: 16-23.
5. Qiu L, List EO, Kopchick JJ,. Differentially expressed proteins in the pancreas of diet-induced diabetic mice. Mol Cell Proteomics 2005; 4: 1311-1318.
6. Fellmann L, Nascimento AR, Tibirica E, Bousquet P,. Murine models for pharmacological studies of the metabolic syndrome. Pharmacol Ther 2013; 137: 331-340.
7. Reinke JM, Sorg H,. Wound repair and regeneration. Eur Surg Res 2012; 49: 35-43.
8. Reeves PG, Nielsen FH, Fahey GC,. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc Whiting Committe on the reformulation of the AIN-76A rodent diet. J Nutr 1993; 123: 1939-1951.
9. Cattaneo L, De Gennaro Colonna V, Zoli M, Muller EE, Cocchi D,. Hypothalamo-pituitary-IGF-1 axis in female rats made obese by overfeeding. Life Sci 1997; 61: 881-889.
10. Otranto M, Do Nascimento AP, Monte-Alto-Costa A,. Effects of supplementation with different edible oils on cutaneous wound healing. Wound Repair Regen 2010; 18: 629-636.
11. Anwer T, Sharma M, Pillai KK, Iqbal M,. Effect of Withania somnifera on insulin sensitivity in non-insulin-dependent diabetes mellitus rats. Basic Clin Pharmacol Toxicol 2008; 102: 498-503.
12. Bhatt PA, Makwana D,. Comparative influence of propranolol and verapamil on glycemic control and histamine sensitivity associated with L-thyroxine-induced hyperthyroidism-an experimental study. Fundam Clin Pharmacol 2008; 22: 53-59.
13. Woessner JF, Jr,. The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. Arch Biochem Biophys 1961; 93: 440-447.
14. Schaffer MR, Efron PA, Thornton FJ, Klingel K, Gross SS, Barbul A,. Nitric oxide, an autocrine regulator of wound fibroblast synthetic function. J Immunol 1997; 158: 2375-2381.
15. Green LC, Wagner DA, Glogowski J, Skipper PL, Wishnok JS, Tannenbaum SR,. Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Anal Biochem 1982; 126: 131-138.
16. Stark JM, van Egmond AW, Zimmerman JJ, Carabell SK, Tosi MF,. Detection of enhanced neutrophil adhesion to parainfluenza-infected airway epithelial cells using a modified myeloperoxidase assay in a microtiter format. J Virol Methods 1992; 40: 225-242.
17. Draper HH, Squires EJ, Mahmoodi H, Wu J, Agarwal S, Hadley M,. A comparative evaluation of thiobarbituric acid methods for the determination of malondialdehyde in biological materials. Free Radic Biol Med 1993; 15: 353-363.
18. Levine RL, Garland D, Oliver CN, Amici A, Climent I, Lenz AG, et al. Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol 1990; 186: 464-478.
19. Schaffer MR, Tantry U, Efron PA, Ahrendt GM, Thornton FJ, Barbul A,. Diabetes-impaired healing and reduced wound nitric oxide synthesis: a possible pathophysiologic correlation. Surgery 1997; 121: 513-519.
20. Oscai LB, Brown MM, Miller WC,. Effect of dietary fat on food intake, growth and body composition in rats. Growth 1984; 48: 415-424.
21. Riccardi G, Giacco R, Rivellese AA,. Dietary fat, insulin sensitivity and the metabolic syndrome. Clin Nutr 2004; 23: 447-456.
22. Paulino do Nascimento A, Monte-Alto-Costa A,. Both obesity-prone and obesity-resistant rats present delayed cutaneous wound healing. Br J Nutr 2011; 106: 603-611.
23. Wellen KE, Hotamisligil GS,. Inflammation, stress, and diabetes. J Clin Invest 2005; 115: 1111-1119.
24. Maritim AC, Sanders RA, Watkins JB 3rd,. Diabetes, oxidative stress, and antioxidants: a review. J Biochem Mol Toxicol 2003; 17: 24-38.
25. Fardoun RZ,. The use of vitamin E in type 2 diabetes mellitus. Clin Exp Hypertens 2007; 29: 135-148.
26. Yosipovitch G, DeVore A, Dawn A,. Obesity and the skin: skin physiology and skin manifestations of obesity. J Am Acad Dermatol 2007; 56: 901-916.
27. Desmouliere A, Redard M, Darby I, Gabbiani G,. Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar. Am J Pathol 1995; 146: 56-66.
28. Toriseva M, Laato M, Carpen O, Ruohonen ST, Savontaus E, Inada M, et al. MMP-13 regulates growth of wound granulation tissue and modulates gene expression signatures involved in inflammation, proteolysis, and cell viability. PLoS ONE 2012; 7: e42596.
29. Li J, Chen J, Kirsner R,. Pathophysiology of acute wound healing. Clin Dermatol 2007; 25: 9-18.
30. Gurtner GC, Werner S, Barrandon Y, Longaker MT,. Wound repair and regeneration. Nature 2008; 453: 314-321.