Comparative influence of propranolol and verapamil on glycemic control and histamine sensitivity associated with l-thyroxine-induced hyperthyroidism - An experimental study

Fundamental and Clinical Pharmacology

Volumn 22, Issue 1, 2008, Pages 53-59

  Bhatt, Parloop A ^a   Makwana, Dharmesh ^a  

^a L M COLLEGE OF PHARMACY   (India)

Author keywords

Glycemic control; Histamine sensitivity; Hyperthyroidism; Propranolol; Verapamil

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; GLUCOSE; HISTAMINE; INSULIN; LEVOTHYROXINE; PROPRANOLOL; THYROTROPIN; VERAPAMIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY TEMPERATURE; BODY WEIGHT; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLYCEMIC CONTROL; GUINEA PIG; HYPERGLYCEMIA; HYPERINSULINEMIA; HYPERTHYROIDISM; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; RAT; THYROTOXICOSIS; THYROTROPIN BLOOD LEVEL;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; ASPHYXIA; BLOOD GLUCOSE; CALCIUM CHANNEL BLOCKERS; FEMALE; GUINEA PIGS; HISTAMINE; HYPERTHYROIDISM; INSULIN; PROPRANOLOL; RATS; RATS, WISTAR; THYROTROPIN; THYROXINE; TRIIODOTHYRONINE; VERAPAMIL;

EID: 38649095201     PISSN: 07673981     EISSN: 14728206     Source Type: Journal    
DOI: 10.1111/j.1472-8206.2007.00559.x     Document Type: Article

References (38)

1. Fadel B.M., Ellahham S., Ringel M.D., Lindsay J., Wartofsky L., Burman K.D. Hyperthyroid heart disease. Clin. Cardiol. (2000) 23 402 408.
2. Faber J., Winberg N., Schifter S., Mehlsen J. Haemodynamic changes following treatment of subclinical and overt hyperthyroidism. Eur. J. Endocrinol. (2001) 145 391 396.
3. Tauveron I. Impairment of glucose tolerance in hyperthyroidism. Diabetes Metab. (1992) 18/1 131 136.
4. Dimitriadis G.D., Raptis S.A. Thyroid hormone excess and glucose intolerance. Exp. Clin. Endocrinol. Diabetes (2001) 109 S225 S239. doi.
5. Weinstein S.P., O'Boyle E., Fisher M., Haber R.S. Regulation of Glut 2 glucose transporter expression in liver by thyroid hormone: evidence for hormonal regulation of the hepatic glucose transport system. Endocrinology (1994) 135 649 654. doi:.
6. Mokuno T., Uchimura K., Hayashi R., Hayakawa H., Sawai Y., Kotake M. Glucose transporter 2 concentrations in hyper- and hypothyroid rat livers. J. Endocrinol. (1999) 160 285 289. doi:.
7. Matthaei S., Trost B., Hamann A., Kausch C., Benecke H., Greten H. Effect of in vivo thyroid hormone status on insulin signalling and GLUT 1 and GLUT 4 glucose transport system in rat adipocytes. J. Endocrinol. (1995) 144 347 357.
8. Mackowiak P., Ginalska E., Nowak- Strojec E., Szkudelski T. The influence of hypo- and hyperthyroidism on insulin receptors and metabolism. Arch. Physiol. Biochem. (1999) 107 273 279.
9. Gottlieb P.A., Braveman L.E. The effect of thyroid disease on diabetes. Clin. Diabetes (1994) 12 15 18.
10. Gasinka T., Wawrzyniak L. Glucose tolerance and insulin secretion in patients with hyperthyroidism: pathogenesis of disturbances and therapeutic consequences. Pol. Tyg. Lek. (1994) 49 43 45.
11. Diekmann M.J., Anghelescu N., Endert E., Bakker O., Wiersinga W.M. Changes in plasma low-density lipoprotein (LDL) and high density lipoprotein cholesterol in hypo- and hyperthyroid patients are related to changes in free thyroxin, not to polymorphisms in LDL receptor or cholesterol ester transfer protein genes. J. Clin. Endocrinol. Metab. (2000) 85 1857 1862. doi:.
12. Einhorn D. An overview of the diagnosis and treatment of the patient with thyroid disease. Mod. Med. (1990) 58 36 55.
13. Geffner D.L., Hershman J.M. Beta adrenergic blockade for the treatment of hyperthyroidism. Am. J. Med. (1992) 93 61 68. doi:.
14. Bakris G.L., Bell D.S., Fonseca V., Katholi R., McGill J., Phillips R. Gemini investigators: the rationale and design of the glycemic effects in diabetes mellitus carvedilol-metoprolol comparison in hypertensives. J. Diabetes Complications (2005) 19 74 79. doi:.
15. Gammage M.D., Logan S.D. Effect of thyroid dysfunction on serum calcium in rats. Clin. Sci. (1986) 71 271 276.
16. Klein M., Pascal V., Aubert V., Weryha G., Danchin N., Leckere J. Heart and thyroid. Ann. Endocrinol. (Paris) (1995) 56 473 486.
17. Opie L.H. International society and federation of cardiology: working groups of classification of calcium antagonists for cardiovascular disease. Am. J. Cardiol. (1987) 60 630 632.
18. Triggle D.J. Calcium antagonist: history and perspective. Stroke (1990) 21 49 58.
19. Krickler D.M. Thyroidal effects and lipid turnover. Br. J. Clin. Pharmacol. (1986) 2 183S 189S.
20. Varricchio M., Balbi V., Varricchio G., Taglianmonte M.R., Gambardella A., Paolisso G. The therapy of aged diabetic hypertensives. Arch. Gerontol. Geriatr. (1996) 93 57 63.
21. Leger J., Masson G.C., Prado J.L. Factors influencing an anaphylactoid reaction in the rat. Proc. Fed. Am. Soc. Exp. Biol. (1947) 6 150 151.
22. Gotzl F.R., Dragstedt C.A. Effect of thyroidectomy and of experimental hyperthyroidism upon histamine content of rat tissue. Proc. Soc. Exp. Biol. Med. (1940) 45 688 689.
23. Schayer R.W., Smiley R.L., Davis K.J. Inhibition by cortisone of the binding of new histamine in rat tissues. Proc. Soc. Exp. Biol. Med. (1954) 87 590 592.
24. Ahmed T., Russi E., Kim C.S. Comparative effects of oral and inhaled verapamil on antigen induced bronchoconstriction. Chest (1985) 88 176.
25. Fanta C.H. Calcium channel blockers in prophylaxis and treatment of asthma. Am. J. Cardiol. (1985) 55 202B 209B.
26. Chand N., Pillar J., Diamantis W., Sofia R.D. Invitro inhibition of allergic histamine release by calcium antagonist. Eur. J. Pharmacol. (1985) 107 353 358.
27. Jensen C., Stahl-Skov P., Norn S. Inhibitory effects of calcium antagonist on histamine release from human leucocytes: in vivo and in vitro experiments. Allergy (1983) 38 233.
28. Alford F.P., Martin F.R., Pearson M.J. Significance and interpretation of mildly abnormal OGTT. Diabetologia (1971) 7 173 180. doi:.
29. Kahaly G.J., Nieswandt J., Mohr- Kahaly S. Cardiac risks of hyperthyroidism in the elderly. Thyroid (1998) 8 1165 1167.
30. Gershenghorn M.C. Mechanism of thyrotropin releasing hormone stimulation on pituitary hormone secretion. Annu. Rev. Physiol. (1986) 48 515 526.
31. Degroot L.J. In: Joseph W.L., Morton D.L., Adkins P.C. (Eds The thyroid and its diseases, 5th edn, John Wiley and Sons, New York, 1984, pp. 102 120.
32. Ohguni S., Notsu K., Kato Y. Correlation of plasma free thyroxine levels with insulin sensitivity and metabolic clearance rate of insulin in patients with hyperthyroid Graves disease. Intern. Med. (1995) 34 339 341.
33. Jap T.S., Ho L.T., Won J.G. Insulin secretion and sensitivity in hyperthyroidism. Horm. Metab. Res. (1989) 5 261 266.
34. Hedner T., Samuelsson O., Lindholm L. Effects of antihypertensive therapy on glucose tolerance: focus on calcium antagonists. J. Intern. Med. Suppl. (1991) 735 101 111.
35. Lithell H.O. Insulin resistance as an intermediary endpoint. Blood Press. Suppl. (1997) 2 108 112.
36. Bakris G., Molitch M., Hewkin A. et al. STAR Investigators Differences in glucose tolerance between fixed-dose antihypertensive drug combinations in people with metabolic syndrome. Diabetes Care (2006) 29 2592 2597.
37. Parrat J.R., West G.B. Hypersensitivity and the thyroid gland. Int. Arch. Allergy Appl. Immunol. (1960) 16 288 302.
38. Kojima K., Kume H., Ito S. et al. Direct effects of hydrogen peroxide on airway smooth muscle tone: Roles of Ca(2+) influx and Rho-kinase. Eur. J. Pharmacol. (2006) 10 29 35.