Formulation and characterization of nanostructured lipid carriers containing a mixed lipids core

Colloids and Surfaces A: Physicochemical and Engineering Aspects

Volumn 430, Issue , 2013, Pages 76-84

  Zheng, Minying ^a   Falkeborg, Mia ^b   Zheng, Yan ^a   Yang, Tiankui ^a   Xu, Xuebing ^a,b  

^a Wilmar International Limited   (China)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

Crystallinity; Drug incorporation; Nanostructured lipid carrier (NLC); Particle size; Rheological behavior

Indexed keywords

DIFFERENTIAL SCANNING CALORIMETRY; DYNAMIC LIGHT SCATTERING; ELASTICITY; LINOLEIC ACID; LIPIDS; LIQUIDS; PARTICLE SIZE; RHEOLOGY; TRANSMISSION ELECTRON MICROSCOPY; X RAY DIFFRACTION;

CRYSTALLINITIES; DRUG INCORPORATION; NANOSTRUCTURED LIPID CARRIER (NLC); NANOSTRUCTURED LIPID CARRIERS; PHYSICOCHEMICAL PARAMETERS; RHEOLOGICAL BEHAVIORS; RHEOLOGICAL MEASUREMENTS; TRANSMISSION ELECTRON MICROSCOPY (TEM);

OILS AND FATS;

LIPID; MEDIUM CHAIN TRIACYLGLYCEROL; NANOCARRIER; NANOSTRUCTURED LIPID CARRIER; PALM OIL; RAPESEED OIL; SOYBEAN OIL; SUNFLOWER OIL; TRISTEARIN; UNCLASSIFIED DRUG;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; FLOW KINETICS; LIGHT SCATTERING; MELTING POINT; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY; VISCOSITY; X RAY DIFFRACTION;

EID: 84877347928     PISSN: 09277757     EISSN: 18734359     Source Type: Journal    
DOI: 10.1016/j.colsurfa.2013.03.070     Document Type: Article

References (33)

1. Müller R.H., Mäder K., Gohla S. Solid lipid nanoparticles (SLN) for controlled drug delivery: a review of the state of the art. Eur. J. Pharm. Biopharm. 2000, 50:161-177.
2. Müller R.H., Radtke M., Wissing S.A. Nanostructured lipid matrices for improved microencapsulation of drugs. Int. J. Pharm. 2002, 242:121-128.
3. Müller R.H., Radtke M., Wissing S. A Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations. Adv. Drug Deliv. Rev. 2002, 54(Suppl. 1):S131-S155.
4. Liu D.H., Liu Z.H., Wang L.L., Zhang C., Zhang N. Nanostructured lipid carriers as novel carrier for parenteral delivery of docetaxel. Colloids Surf. B 2011, 85:262-269.
5. Li X., Nie S.F., Kong J., Li N., Ju C.Y., Pan W.S. A controlled-release ocular delivery system for ibuprofen based on nanostructured lipid carriers. Int. J. Pharm. 2008, 363:177-182.
6. Mehnert W., Mäder K. Solid lipid nanoparticles: production, characterization and applications. Adv. Drug Deliv. Rev. 2001, 47:165-196.
7. Jia L.J., Zhang D.R., Li Z.Y., Duan C.X., Wang Y.C., Feng F.F., Wang F.H., Liu Y., Zhang Q. Nanostructured lipid carriers for parenteral delivery of silybin: biodistribution and pharmacokinetic studies. Colloids Surf. B 2010, 80:213-218.
8. Chen C.C., Tsai T.H., Huang Z.R., Fang J.Y. Effects of lipophilic emulsifiers on the oral administration of lovastatin from nanostructured lipid carriers: physicochemical characterization and pharmacokinetics. Eur. J. Pharm. Biopharm. 2010, 74:474-482.
9. Kumbhar D.D., Pokharkar V.B. Engineering of nanostructured lipid carrier of the poorly water-soluble drug, bicalutamide: physicochemical investigations. Colloids Surf. A 2013, 416:32-42.
10. Liu G.Y., Wang J.M., Xia Q. Application of nanostructured lipid carrier in food for the improved bioavailability. Eur. Food Res. Technol. 2012, 234:391-398.
11. Hentschel A., Gramdorf S., Müller R.H., Kurz T. β-Carotene-loaded nanostructured lipid carriers. J. Food Sci. 2008, 73:N1-N6.
12. Loveday S.M., Singh H. Recent advances in technologies for vitamin A protection in foods. Trends Food Sci. Technol. 2008, 19:657-668.
13. Müller R.H., Petersen R.D., Hommoss A., Pardeike J. Nanostructured lipid carriers (NLC) in cosmetic dermal products. Adv. Drug Deliv. Rev. 2007, 59:522-530.
14. Xia Q., Saupe A., Müller R.H., Souto E.B. Nanostructured lipid carriers as novel carrier for sunscreen formulations. Int. J. Cosmet. Sci. 2007, 29:473-482.
15. Han F., Li S., Yin R., Liu H.Z., Xu L. Effect of surfactants on the formation and characterization of a new type of colloidal drug delivery system: nanostructured lipid carriers. Colloids Surf. A 2008, 315:210-216.
16. Kovacevic A., Savic S., Vuleta G., Müller R.H., Keck C.M. Polyhydroxy surfactants for the formulation of lipid nanoparticles (SLN and NLC): effects on size, physical stability and particle matrix structure. Int. J. Pharm. 2011, 406:163-172.
17. Marten B., Pfeuffer M., Schrezenmeir J. Medium-chain triglycerides. Int. Dairy J. 2006, 16:1374-1382.
18. Thiyam U. The other side of rapeseed oil mill: perspective on press cake utilization. Inform 2006, 17:382-383.
19. Zheng M.Y., Liu F., Wang Z.W., Baoyindugurong J.H. Formation and characterization of self-assembling fish oil microemulsion. Colloid J. 2011, 73:319-326.
20. Unruh T., Bunjes H., Westesen K., Koch M.H.J. Investigations on the melting behavior of triglyceride nanoparticles. Colloid Polym. Sci. 2001, 279:398-403.
21. Liu J., Gong T., Wang C.G., Zhong Z.R. Solid lipid nanoparticles loaded with insulin by sodium cholatephosphatidylcholine-based mixed micelles: preparation and characterization. Int. J. Pharm. 2007, 340:153-162.
22. Sato K. Crystallization behaviour of fats and lipids-a review. Chem. Eng. Sci. 2001, 56:2255-2265.
23. Larsson K. Classification of glyceride crystal forms. Acta Chem. Scand. 1966, 20:2255-2260.
24. Sato K., Ueno S., Yano J. Molecular interactions and kinetic properties of fats. Prog. Lipid Res. 1999, 91-116.
25. Jenning V., Gohla S.H. Encapsulation of retinoids in solid lipid nanoparticles. J. Microencapsul. 2001, 18:149-158.
26. 10-loaded NLC versus nanoemulsions: stability, rheology and in vitro skin permeation. Int. J. Pharm. 2009, 377:207-214.
27. Souto E.B., Wissing S.A., Barbosa C.M., Müller R.H. Evaluation of the physical stability of SLN and NLC before and after incorporation into hydrogel formulations. Eur. J. Pharm. Biopharm. 2004, 58:83-90.
28. Paredes J., Shahidzadeh-Bonn N., Bonn D. Shear banding in thixotropic and normal emulsions. J. Phys.-Condens. Mat. 2011, 23:1-8.
29. Akoh C.C., Lai O.M. Healthful Lipids 2004, AOCS Press, Champaign (USA), pp. 249-251.
30. Ip C., Jiang C., Thompson H.J., Scimeca J.A. Retention of conjugated linoleic acid in the mammary gland is associated with tumor inhibition during the post-initiation phase of carcinogenesis. Carcinogenesis 1997, 18:755-759.
31. Nicolosi R.J., Rogers E.J., Kritchevsky D., Scimeca J.A., Huth P.J. Dietary conjugated linoleic acid reduces plasma lipoprotein and early aortic atherosclerosis in hypercholesterolemic hamsters. Artery 1997, 266-277.
32. Jimenez M., García H.S., Beristain C.I. Spray-dried encapsulation of conjugated linoleic acid (CLA) with polymeric matrices. J. Sci. Food Agric. 2006, 2431-2437.
33. Jimenez M., García H.S., Beristain C.I. Effect of water activity on physical properties of conjugated linoleic acid (CLA) microcapsules. J. Food Process Eng. 2010, 33:434-447.