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Volumn 17, Issue 2, 2013, Pages 63-69

New insights into the genetics of neuroblastoma: Implications for diagnosis and therapy

Author keywords

[No Author keywords available]

Indexed keywords

ANAPLASTIC LYMPHOMA RECEPTOR TYROSINE KINASE; ANAPLASTIC LYMPHOMA RECEPTOR TYROSINE KINASE ANTIBODY; ANTINEOPLASTIC AGENT; CRIZOTINIB; ENZYME ANTIBODY; HOMEODOMAIN PROTEIN; PAIRED LIKE HOMEOBOX 2B PROTEIN; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; SMALL INTERFERING RNA; TAE 684; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 84877340550     PISSN: 11771062     EISSN: 11792000     Source Type: Journal    
DOI: 10.1007/s40291-013-0019-6     Document Type: Review
Times cited : (25)

References (66)
  • 1
    • 34250683435 scopus 로고    scopus 로고
    • Neuroblastoma
    • DOI 10.1016/S0140-6736(07)60983-0, PII S0140673607609830
    • Maris JM, Hogarty MD, Bagatell R, Cohn SL. Neuroblastoma. Lancet. 2007;369:2106-20. (Pubitemid 46935947)
    • (2007) Lancet , vol.369 , Issue.9579 , pp. 2106-2120
    • Maris, J.M.1    Hogarty, M.D.2    Bagatell, R.3    Cohn, S.L.4
  • 2
    • 84993876589 scopus 로고
    • Correlating telomerase activity levels with human neuroblastoma outcomes
    • 7585042 10.1038/nm0395-249 1:CAS:528:DyaK2MXksVGnsrY%3D
    • Hiyama E, Hiyama K, Yokoyama T, Matsuura Y, Piatyszek MA, Shay JW. Correlating telomerase activity levels with human neuroblastoma outcomes. Nat Med. 1995;1:249-55.
    • (1995) Nat Med , vol.1 , pp. 249-255
    • Hiyama, E.1    Hiyama, K.2    Yokoyama, T.3    Matsuura, Y.4    Piatyszek, M.A.5    Shay, J.W.6
  • 3
    • 0021261878 scopus 로고
    • Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage
    • Brodeur GM, Seeger RC, Schwab M, Varmus HE, Bishop JM. Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science. 1984;224:1121-4. (Pubitemid 14106392)
    • (1984) Science , vol.224 , Issue.4653 , pp. 1121-1124
    • Brodeur, G.M.1    Seeger, R.C.2    Schwab, M.3
  • 4
    • 34248671388 scopus 로고    scopus 로고
    • Are chromosomal imbalances important in cancer?
    • DOI 10.1016/j.tig.2007.03.009, PII S0168952507001114
    • Stallings RL. Are chromosomal imbalances important in cancer? Trends Genet. 2007;23:278-83. (Pubitemid 46770894)
    • (2007) Trends in Genetics , vol.23 , Issue.6 , pp. 278-283
    • Stallings, R.L.1
  • 5
    • 77749279754 scopus 로고    scopus 로고
    • High-risk neuroblastoma tumors with 11q-deletion display a poor prognostic, chromosome instability phenotype with later onset
    • 20145112 10.1073/pnas.0910684107 1:CAS:528:DC%2BC3cXjsFWiuro%3D
    • Caren H, Kryh H, Nethander M, Sjoberg RM, Trager C, Nilsson S, Abrahamsson J, Kogner P, Martinsson T. High-risk neuroblastoma tumors with 11q-deletion display a poor prognostic, chromosome instability phenotype with later onset. Proc Natl Acad Sci USA. 2010;107:4323-8.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 4323-4328
    • Caren, H.1    Kryh, H.2    Nethander, M.3    Sjoberg, R.M.4    Trager, C.5    Nilsson, S.6    Abrahamsson, J.7    Kogner, P.8    Martinsson, T.9
  • 14
    • 84858248558 scopus 로고    scopus 로고
    • Association of age at diagnosis and genetic mutations in patients with neuroblastoma
    • 22416102 10.1001/jama.2012.228 1:CAS:528:DC%2BC38XksFCisL8%3D
    • Cheung NK, Zhang J, Lu C, Parker M, Bahrami A, Tickoo SK, et al. Association of age at diagnosis and genetic mutations in patients with neuroblastoma. JAMA. 2012;307:1062-71.
    • (2012) JAMA , vol.307 , pp. 1062-1071
    • Cheung, N.K.1    Zhang, J.2    Lu, C.3    Parker, M.4    Bahrami, A.5    Tickoo, S.K.6
  • 20
    • 78049298226 scopus 로고    scopus 로고
    • PHOX2B-mediated regulation of ALK expression: In vitro identification of a functional relationship between two genes involved in neuroblastoma
    • 20957039 10.1371/journal.pone.0013108
    • Bachetti T, Di Paolo D, Di Lascio S, Mirisola V, Brignole C, Bellotti M, et al. PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship between two genes involved in neuroblastoma. PLoS One. 2010;5(10):e13108.
    • (2010) PLoS One , vol.5 , Issue.10 , pp. 13108
    • Bachetti, T.1    Di Paolo, D.2    Di Lascio, S.3    Mirisola, V.4    Brignole, C.5    Bellotti, M.6
  • 21
    • 0031008896 scopus 로고    scopus 로고
    • ALK the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)
    • Morris SW, Naeve C, Mathew P, James PL, Kirstein MN, Cui X, Witte DP. ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK). Oncogene. 1997;14:2175-88. (Pubitemid 27248229)
    • (1997) Oncogene , vol.14 , Issue.18 , pp. 2175-2188
    • Morris, S.W.1    Naeve, C.2    Mathew, P.3    James, P.L.4    Kirstein, M.N.5    Cui, X.6    Witte, D.P.7
  • 22
    • 0032830033 scopus 로고    scopus 로고
    • Identification of novel chromosomal rearrangements in acute myelogenous leukemia involving loci on chromosome 2p23, 15q22 and 17q21
    • Melnick A, Fruchtman S, Zelent A, Liu M, Huang Q, Boczkowska B, Calasanz M, Fernandez A, Licht JD, Najfeld V. Identification of novel chromosomal rearrangements in acute myelogenous leukemia involving loci on chromosome 2p23, 15q22 and 17q21. Leukemia. 1999;13:1534-8. (Pubitemid 29465615)
    • (1999) Leukemia , vol.13 , Issue.10 , pp. 1534-1538
    • Melnick, A.1    Fruchtman, S.2    Zelent, A.3    Liu, M.4    Huang, Q.5    Boczkowska, B.6    Calasanz, M.J.7    Fernandez, A.8    Licht, J.D.9    Najfeld, V.10
  • 23
    • 0030789212 scopus 로고    scopus 로고
    • Diffuse large cell, B-cell type lymphoma with a novel translocation (2;22)(p23;q11.2)
    • DOI 10.1016/S0165-4608(96)00281-6, PII S0165460896002816
    • Park JP, Curran MJ, Levy NB, Davis TH, Elliott JH, Mohandas TK. Diffuse large cell, B-cell type lymphoma with a novel translocation (2;22)(p23;q11.2). Cancer Genet Cytogenet. 1997;96:118-22. (Pubitemid 27287485)
    • (1997) Cancer Genetics and Cytogenetics , vol.96 , Issue.2 , pp. 118-122
    • Park, J.P.1    Curran, M.J.2    Levy, N.B.3    Davis, T.H.4    Elliott, J.H.5    Mohandas, T.K.6
  • 24
    • 0030022316 scopus 로고    scopus 로고
    • The t(5; 17) variant of acute promyelocytic leukemia expresses a nucleophosmin-retinoic acid receptor fusion
    • Redner RL, Rush EA, Faas S, Rudert WA, Corey SJ. The t(5;17) variant of acute promyelocytic leukemia expresses a nucleophosmin-retinoic acid receptor fusion. Blood. 1996;87:882-6. (Pubitemid 26043517)
    • (1996) Blood , vol.87 , Issue.3 , pp. 882-886
    • Redner, R.L.1    Rush, E.A.2    Faas, S.3    Rudert, W.A.4    Corey, S.J.5
  • 27
    • 58149289668 scopus 로고    scopus 로고
    • High incidence of DNA mutations and gene amplifications of the ALK gene in advanced sporadic neuroblastoma tumours
    • 18990089 10.1042/BJ20081834 1:CAS:528:DC%2BD1cXhtlGls7bO
    • Caren H, Abel F, Kogner P, Martinsson T. High incidence of DNA mutations and gene amplifications of the ALK gene in advanced sporadic neuroblastoma tumours. Biochem J. 2008;416:153-9.
    • (2008) Biochem J , vol.416 , pp. 153-159
    • Caren, H.1    Abel, F.2    Kogner, P.3    Martinsson, T.4
  • 32
    • 80655124524 scopus 로고    scopus 로고
    • Emerging importance of ALK in neuroblastoma
    • 21945349 10.1016/j.semcancer.2011.09.005 1:CAS:528:DC%2BC3MXhsVSktLzN
    • Azarova AM, Gautam G, George RE. Emerging importance of ALK in neuroblastoma. Semin Cancer Biol. 2011;21:267-75.
    • (2011) Semin Cancer Biol , vol.21 , pp. 267-275
    • Azarova, A.M.1    Gautam, G.2    George, R.E.3
  • 33
    • 79960122166 scopus 로고    scopus 로고
    • Genome-wide linkage analysis to identify genetic modifiers of ALK mutation penetrance in familial neuroblastoma
    • 21734404 10.1159/000324843 1:CAS:528:DC%2BC3MXos1ehsLs%3D
    • Devoto M, Specchia C, Laudenslager M, Longo L, Hakonarson H, Maris J, Mosse Y. Genome-wide linkage analysis to identify genetic modifiers of ALK mutation penetrance in familial neuroblastoma. Hum Hered. 2011;71:135-9.
    • (2011) Hum Hered , vol.71 , pp. 135-139
    • Devoto, M.1    Specchia, C.2    Laudenslager, M.3    Longo, L.4    Hakonarson, H.5    Maris, J.6    Mosse, Y.7
  • 35
    • 0037194586 scopus 로고    scopus 로고
    • Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines
    • DOI 10.1038/sj.onc.1205735
    • Miyake I, Hakomori Y, Shinohara A, Gamou T, Saito M, Iwamatsu A, Sakai R. Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines. Oncogene. 2002;21:5823-34. (Pubitemid 35007232)
    • (2002) Oncogene , vol.21 , Issue.38 , pp. 5823-5834
    • Miyake, I.1    Hakomori, Y.2    Shinohara, A.3    Gamou, T.4    Saito, M.5    Iwamatsu, A.6    Sakai, R.7
  • 39
    • 0031035052 scopus 로고    scopus 로고
    • Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system
    • Iwahara T, Fujimoto J, Wen D, Cupples R, Bucay N, Arakawa T, Mori S, Ratzkin B, Yamamoto T. Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system. Oncogene. 1997;14:439-49. (Pubitemid 27087107)
    • (1997) Oncogene , vol.14 , Issue.4 , pp. 439-449
    • Iwahara, T.1    Fujimoto, J.2    Wen, D.3    Cupples, R.4    Bucay, N.5    Arakawa, T.6    Mori, S.7    Ratzkin, B.8    Yamamoto, T.9
  • 40
    • 4344662463 scopus 로고    scopus 로고
    • ALK receptor tyrosine kinase promotes cell growth and neurite outgrowth
    • DOI 10.1242/jcs.01183
    • Motegi A, Fujimoto J, Kotani M, Sakuraba H, Yamamoto T. ALK receptor tyrosine kinase promotes cell growth and neurite outgrowth. J Cell Sci. 2004;117:3319-29. (Pubitemid 39139916)
    • (2004) Journal of Cell Science , vol.117 , Issue.15 , pp. 3319-3329
    • Motegi, A.1    Fujimoto, J.2    Kotani, M.3    Sakuraba, H.4    Yamamoto, T.5
  • 41
  • 42
    • 66949152073 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase: Signalling in development and disease
    • 19459784 10.1042/BJ20090387 1:CAS:528:DC%2BD1MXmtlOls7c%3D
    • Palmer RH, Vernersson E, Grabbe C, Hallberg B. Anaplastic lymphoma kinase: signalling in development and disease. Biochem J. 2009;420:345-61.
    • (2009) Biochem J , vol.420 , pp. 345-361
    • Palmer, R.H.1    Vernersson, E.2    Grabbe, C.3    Hallberg, B.4
  • 44
    • 0037184128 scopus 로고    scopus 로고
    • Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types
    • 12122009 10.1074/jbc.M205749200 1:CAS:528:DC%2BD38XnsVCjs78%3D
    • Stoica GE, Kuo A, Powers C, Bowden ET, Sale EB, Riegel AT, Wellstein A. Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types. J Biol Chem. 2002;277:35990-8.
    • (2002) J Biol Chem , vol.277 , pp. 35990-35998
    • Stoica, G.E.1    Kuo, A.2    Powers, C.3    Bowden, E.T.4    Sale, E.B.5    Riegel, A.T.6    Wellstein, A.7
  • 46
    • 84055178183 scopus 로고    scopus 로고
    • Inhibition of N-linked glycosylation impairs ALK phosphorylation and disrupts pro-survival signaling in neuroblastoma cell lines
    • 22192458 10.1186/1471-2407-11-525
    • Del Grosso F, De Mariano M, Passoni L, Luksch R, Tonini GP, Longo L. Inhibition of N-linked glycosylation impairs ALK phosphorylation and disrupts pro-survival signaling in neuroblastoma cell lines. BMC Cancer. 2011;11:525.
    • (2011) BMC Cancer , vol.11 , pp. 525
    • Del Grosso, F.1    De Mariano, M.2    Passoni, L.3    Luksch, R.4    Tonini, G.P.5    Longo, L.6
  • 47
    • 42549119526 scopus 로고    scopus 로고
    • Development of anaplastic lymphoma kinase (ALK) small-molecule inhibitors for cancer therapy
    • DOI 10.1002/med.20109
    • Li R, Morris SW. Development of anaplastic lymphoma kinase (ALK) small-molecule inhibitors for cancer therapy. Med Res Rev. 2008;28:372-412. (Pubitemid 351590540)
    • (2008) Medicinal Research Reviews , vol.28 , Issue.3 , pp. 372-412
    • Li, R.1    Morris, S.W.2
  • 54
    • 84862286182 scopus 로고    scopus 로고
    • Inhibitors of the anaplastic lymphoma kinase
    • 22612599 10.1517/13543784.2012.690031 1:CAS:528:DC%2BC38Xos1Slt7g%3D
    • Mologni L. Inhibitors of the anaplastic lymphoma kinase. Expert Opin Investig Drugs. 2012;21:985-94.
    • (2012) Expert Opin Investig Drugs , vol.21 , pp. 985-994
    • Mologni, L.1
  • 58
    • 84869400315 scopus 로고    scopus 로고
    • Antibody targeting of anaplastic lymphoma kinase induces cytotoxicity of human neuroblastoma
    • 10.1038/onc.2012.208 1:CAS:528:DC%2BC38Xhs1OgsLnK
    • Carpenter EL, Haglund EA, Mace EM, Deng D, Martinez D, Wood AC, et al. Antibody targeting of anaplastic lymphoma kinase induces cytotoxicity of human neuroblastoma. Oncogene. 2012;31(46):4888.
    • (2012) Oncogene , vol.31 , Issue.46 , pp. 4888
    • Carpenter, E.L.1    Haglund, E.A.2    MacE, E.M.3    Deng, D.4    Martinez, D.5    Wood, A.C.6
  • 59
    • 38549166548 scopus 로고    scopus 로고
    • Aberrant splicing of the PTPRD gene mimics microdeletions identified at this locus in neuroblastomas
    • DOI 10.1002/gcc.20521
    • Nair P, De Preter K, Vandesompele J, Speleman F, Stallings RL. Aberrant splicing of the PTPRD gene mimics microdeletions identified at this locus in neuroblastomas. Genes Chromosomes Cancer. 2008;47:197-202. (Pubitemid 351162850)
    • (2008) Genes Chromosomes and Cancer , vol.47 , Issue.3 , pp. 197-202
    • Nair, P.1    DePreter, K.2    Vandesompele, J.3    Speleman, F.4    Stallings, R.L.5
  • 60
    • 33645749497 scopus 로고    scopus 로고
    • High-resolution analysis of chromosomal breakpoints and genomic instability identifies PTPRD as a candidate tumor suppressor gene in neuroblastoma
    • 16585193 10.1158/0008-5472.CAN-05-4154 1:CAS:528:DC%2BD28XjtVOrtro%3D
    • Stallings RL, Nair P, Maris JM, Catchpoole D, McDermott M, O'Meara A, Breatnach F. High-resolution analysis of chromosomal breakpoints and genomic instability identifies PTPRD as a candidate tumor suppressor gene in neuroblastoma. Cancer Res. 2006;66:3673-80.
    • (2006) Cancer Res , vol.66 , pp. 3673-3680
    • Stallings, R.L.1    Nair, P.2    Maris, J.M.3    Catchpoole, D.4    McDermott, M.5    O'Meara, A.6    Breatnach, F.7
  • 63
    • 77956282773 scopus 로고    scopus 로고
    • Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres
    • 20651253 10.1073/pnas.1008850107 1:CAS:528:DC%2BC3cXhtVCktrfO
    • Lewis PW, Elsaesser SJ, Noh KM, Stadler SC, Allis CD. Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication- independent chromatin assembly at telomeres. Proc Natl Acad Sci USA. 2010;107:14075-80.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 14075-14080
    • Lewis, P.W.1    Elsaesser, S.J.2    Noh, K.M.3    Stadler, S.C.4    Allis, C.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.