Comparative Proteomics Analysis Suggests that Placental Mitochondria are Involved in the Development of Pre-Eclampsia

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Shi, Zhonghua ^a   Long, Wei ^a   Zhao, Chun ^a   Guo, Xirong ^a   Shen, Rong ^a   Ding, Hongjuan ^a  

^a WOMEN S HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

REACTIVE OXYGEN METABOLITE;

ADULT; APOPTOSIS; ARTICLE; CITRIC ACID CYCLE; CLINICAL ARTICLE; CONTROLLED STUDY; DEGENERATION; DOWN REGULATION; ELECTRON MICROSCOPY; FATTY ACID OXIDATION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIQUID CHROMATOGRAPHY; MITOCHONDRION; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PATHOGENESIS; PLACENTA; PREECLAMPSIA; PROTEIN EXPRESSION; PROTEOMICS; RESPIRATORY CHAIN; TANDEM MASS SPECTROMETRY; UPREGULATION; WESTERN BLOTTING;

ADULT; BLOTTING, WESTERN; CHROMATOGRAPHY, LIQUID; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; PLACENTA; PRE-ECLAMPSIA; PREGNANCY; PREGNANCY PROTEINS; PROTEOMICS; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; YOUNG ADULT;

EID: 84877328461     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0064351     Document Type: Article

References (35)

1. Hung T, Skepper JN, Charnock-Jones DS, Burton GJ, (2002) A potent inducer of apoptotic changes in the human placenta and possible etiological factor in Preeclampsia. Circulation Research 90: 1274-81.
2. Cunningham FG, Leveno KJ, Bloom SL, Hauth JC (2005) Williams Obstetrics. 22nd Edn. New York: McGraw-Hill. 761-808.
3. Robert JM (2004) Maternal Fetal Medicine, 5th Edn. W. B. Saunders, Philadelphia. 859-899.
4. Young NK, Hyoung KK, Mohamad W, Nari K, Won SP, et al. (2007) Toward a better understanding of preeclampsia: Comparative proteomic analysis of preeclamptic placentae. Proteomics Clin Appl 1: 1625-36.
5. Martin W, Hans S, Manfred GM, (1998) Pre-eclampsia: a disorder of placental mitochondria? Mol Med Today 4: 286-91.
6. Torbergsen T, Oian P, Mathiesen E, Borud O, (1989) Pre-eclampsia: a mitochondrial disease? Acta Obstet Gynecol Scand 68: 145-8.
7. Wang Y, Walsh SW, (1998) Placental mitochondria as a source of oxidative stress in pre-eclampsia. Placenta 19: 581-6.
8. Shibata E, Nanri H, Ejima K, Araki M, Fukuda J, et al. (2003) Enhancement of mitochondrial oxidative stress and up-regulation of antioxidant protein peroxiredoxin III/SP-22 in the mitochondria of human pre-eclamptic placentae. Placenta 24: 698-705.
9. Padmini E, Lavanya S, Uthra V, (2009) Preeclamptic placental stress and over expression of mitochondrial HSP70. Clin Chem Lab Med 47: 1073-80.
10. Jiang Y, Wang X, (2012) Comparative mitochondrial proteomics: perspective in human diseases. J Hematol Oncol 18 5: 11.
11. Wu WW, Wang G, Baek SJ, Shen RF, (2006) Comparative study of three proteomic quantitative methods, DIGE, cICAT, and iTRAQ, using 2D Gelor LC-MALDI TOF/TOF. J Proteome Res 5: 651-8.
12. Ross PL, Huang YN, Marchese JN, Williamson B, Parker K, et al. (2004) Multiplexed protein quantitation in saccharomyces cerevisiae using amine-reactive isobaric tagging reagents. Mol Cell Proteomics 3: 1154-69.
13. Sun C, Song C, Ma Z, Xu K, Zhang Y, et al. (2011) Periostin identified as potential biomarker of prostate cancer by iTRAQ-proteomics analysis of prostate biopsy. Proteome Sci 9: 22.
14. Watson AL, Skepper JN, Jauniaux E, Burton GJ, (1998) Susceptibility of human placental syncytiotrophoblastic mitochondria to oxygen-mediated damage in relation to gestational age. J Clin Endocrinol Metab 83: 1697-705.
15. Glen A, Evans CA, Gan CS, Cross SS, Hamdy FC, (2010) Eight-plex iTRAQ analysis of variant metastatic human prostate cancer cells identifies candidate biomarkers of progression: An exploratory study. Prostate 70: 1313-32.
16. Glen A, Gan CS, Hamdy FC, Eaton CL, Cross SS, (2008) iTRAQ-facilitated proteomic analysis of human prostate cancer cells identifies proteins associated with progression. J Proteome Res 7: 897-907.
17. Khatun R, Wu Y, Kanenishi K, Ueno M, Tanaka S, et al. (2003) Immunohistochemical study of transferrin receptor expression in the placenta of preeclampticpregnancy. Placenta 24: 870-6.
18. Nikitin A, Egorov S, Daraselia N, (2003) Pathway studio-the analysis and navigation of molecular networks. Bioinformatics 19: 2155-7.
19. Pollard HB, Eidelman O, Jozwik C, (2006) De novo biosynthetic profiling of high abundance proteins in cystic fibrosis lung epithelial cells. Mol Cell Proteomics 5: 1628-37.
20. Roberts JM, Lain KY, (2002) Recent insights into the pathogenesis of pre-eclampsia. Placenta 23: 359-72.
21. Maynard SE, Min JY, Merchan J, Lim KH, Li J, et al. (2003) Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J Clin Invest 111: 649-58.
22. Brosens IA, Robertson WB, Dixon HG, (1972) The role of the spiral arteries in the pathogenesis of preeclampsia. Obstet Gynecol Annu 1: 177-91.
23. Fisher SJ, (2004) The placental problem: linking abnormal cytotrophoblast differentiation to the maternal symptoms of preeclampsia. Reprod Biol Endocrinol 2: 53.
24. Huppertz B, Kadyrov M, Kingdom JC, (2006) Apoptosis and its role in the trophoblast. Am J Obstet Gynecol 195: 29-39.
25. Illsinger S, Janzen N, Sander S, Schmidt KH, Bednarczyk J, et al. (2010) Preeclampsia and HELLP syndrome: impaired mitochondrial function in umbilical ensothelial cells. Reprod Sci 17: 219-26.
26. Kirkinezos IG, Moraes CT, (2001) Reactive oxygen species and mitochondrial diseases. Semin Cell Dev Bio 12: 449-57.
27. Leung DN, Smith SC, To KF, Sahota DS, Baker PN, (2001) Increased placental apoptosis in pregnancies complicated by preeclampsia. Am J Obstet Gynecol 184: 1249-50.
28. Sharp AN, Heazell AE, Crocker IP, Mor G, (2010) Placental apoptosis in health and disease. Am J Reprod Immunol 64: 59-69.
29. Redman CW, Sargent IL, (2005) Placental debris, oxiative stress and pre-eclampsia. Science 308: 1592-4.
30. Bartha JL, Visiedo F, Fernández-Deudero A, Bugatto F, Perdomo G, (2012) Decreased mitochondrial fatty acid oxidation in placentas from women with Preeclampsia. Placenta 33: 132-4.
31. Shekhawat P, Bennett MJ, Sadovsky Y, Nelson DM, Rakheja D, et al. (2003) Human placenta metabolizes fatty acids: implications for fetal fatty acid oxidation disorders and maternal liver diseases. Am J Physiol Endocrinol Metab 284: E1098-105.
32. Haggarty P, Allstaff S, Hoad G, Ashton J, Abramovich DR, (2002) Placental nutrient transfer capacity and fetal growth. Placenta 23: 86-92.
33. Herrera E, Amusquivar E, Lopez-Soldado I, Ortega H, (2006) Maternal lipid metabolism and placental lipid transfer. Horm Res 65Suppl 3: 59-64.
34. Rakheja D, Bennett MJ, Foster BM, Domiati-Saad R, Rogers BB, (2002) Evidence for fatty acid oxidation in human placenta, and the relationship of fatty acid oxidation enzyme activities with gestational age. Placenta 23: 447-50.
35. Shekhawat PS, Matern D, Strauss AW, (2005) Fetal fatty acid oxidation disorders, their effect on maternal health and neonatal outcome: impact of expanded newborn screening on their diagnosis and management. Pediatr Res 57: 78R-86R.