Arginine transport is impaired in C57Bl/6 mouse macrophages as a result of a deletion in the promoter of Slc7a2 (CAT2), and susceptibility to Leishmania infection is reduced

Journal of Infectious Diseases

Volumn 207, Issue 11, 2013, Pages 1684-1693

  Sans Fons, M Gloria ^a   Yeramian, Andrée ^a   Pereira Lopes, Selma ^a   Santamaría Babi, Luis F ^a   Modolell, Manuel ^b   Lloberas, Jorge ^a   Celada, Antonio ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

Author keywords

amino acid transporter; arginine; immune response; Leishmania; macrophage; susceptibility

Indexed keywords

AMINO ACID TRANSPORTER; ARGINASE 1; ARGININE; CYTOKINE; INDUCIBLE NITRIC OXIDE SYNTHASE;

AMINO ACID TRANSPORT; ANIMAL CELL; ARTICLE; BAGG ALBINO MOUSE; BONE MARROW DERIVED MACROPHAGE; C57BL 6 MOUSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; GENE DELETION; IMMUNOREGULATION; INFECTION SENSITIVITY; LEISHMANIASIS; MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INDUCTION; TH1 CELL; TH2 CELL; TRINUCLEOTIDE REPEAT;

AMINO ACID TRANSPORT SYSTEMS, BASIC; ANIMALS; ARGININE; BIOLOGICAL TRANSPORT; CELLS, CULTURED; DISEASE RESISTANCE; LEISHMANIA MAJOR; LEISHMANIASIS; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PROMOTER REGIONS, GENETIC; SEQUENCE DELETION;

EID: 84877284829     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jit084     Document Type: Article

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