Recent progress of the Golgi technique and electron microscopy to examine dendritic pathology in Alzheimer's disease

Future Neurology

Volumn 8, Issue 3, 2013, Pages 239-242

  Baloyannis, Stavros J ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

Alzheimer's disease; dendrite; dendritic spine; electron microscopy; Golgi staining; synapse

Indexed keywords

AMYLOID BETA PROTEIN;

ALZHEIMER DISEASE; AUDITORY CORTEX; BRAIN DEGENERATION; BRAIN MITOCHONDRION; CELL LOSS; CELL MATURATION; CELL STRUCTURE; CEREBELLUM; CONFOCAL MICROSCOPY; DENDRITE; DENDRITIC CELL; DENDRITIC SPINE; DISEASE ASSOCIATION; ELECTRON MICROSCOPY; GOLGI STAIN; GRANULE CELL; IMMUNOCYTOCHEMISTRY; LEARNING; MEMORY; MENTAL FUNCTION; MOSSY FIBER; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NERVE FIBER; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; NISSL STAINING; PATHOGENESIS; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTOPLASMATIC ASTROCYTE; PURKINJE CELL; REVIEW; SENESCENCE; SENILE PLAQUE; SILVER IMPREGNATION; SYNAPSE; VESTIBULAR SYSTEM; VISUAL CORTEX;

EID: 84877249758     PISSN: 14796708     EISSN: 17486971     Source Type: Journal    
DOI: 10.2217/fnl.13.10     Document Type: Review

References (26)

1. Golgi C. On the structure of nerve cells 1896. J. Microsc. 155, 3-7 (1969).
2. Ramon y Cajal S. Neuron Theory or Reticular Theory? Objective Evidence of the Anatomical Unity of the Nerve Cells. Consejo Superior de Investigaciones Cientificas, Madrid, Spain (1954).
3. Scheibel ME, Scheibel AB. The methods of Golgi. In: Neuroanatomical Research Techniques. Robertson RT (Ed.). Academic Press, NY, USA, 90-114 (1978).
4. Levine ND, Rademacher DJ, Collier TJ et al. Advances in thin tissue Golgi-Cox impregnation: fast, reliable methods for multi-assay analyses in rodent and non-human primate brain. J. Neurosci. Methods 213(2), 214-227 (2013).
5. Fiala JC, Spacek J, Harris KM. Dendritic spine pathology: cause or consequence of neurological disorders? Brain Res. Rev. 39, 29-54 (2002).
6. Penzes P, Cahill ME, Jones KA et al. Dendritic spine pathology in neuropsychiatric disorders. Nat. Neurosci. 14, 285-293 (2011).
7. Terry RD, Katzman R. Senile dementia of the Alzheimer type. Ann. Neurol. 14, 497-506 (1983).
8. Wendou Y, Bingwei L. Synapses and dendritic spines as pathogenic targets in Alzheimer's disease. Neural Plast. 2012, 247150 (2012).
9. Baloyannis SJ. Dendritic pathology in Alzheimer's disease. J. Neurol. Sci. 283, 153-157 (2009).
10. Baloyannis SJ, Costa V, Mauroudis I et al. Dendritic and spinal pathology in the acoustic cortex in Alzheimer's disease: morphological and morphometric estimation by Golgi technique and electron microscopy. Acta Otolaryngol. 127, 351-354 (2007).
11. Mavroudis IA, Fotiou DF, Adipepe LF et al. Morphological changes of the human purkinje cells and deposition of neuritic plaques and neurofibrillary tangles on the cerebellar cortex of Alzheimer's disease. Am. J. Alzh. Dis. Oth. Dement. 25, 585-591 (2010).
12. Baloyannis SJ, Manolidis SL, Manolidis LS. Synaptic alterations in the vestibulocerebellar system in Alzheimer's disease - a Golgi and electron microscope study. Acta Otolaryngol. 120, 247-250 (2000).
13. Yoshiyama Y, Higuchi M, Zhang B et al. Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model. Neuron 53, 337-351 (2007).
14. Baloyannis SJ, Mavroudis I, Manolidis SL, Manolidis LS. Synaptic alterations in the medial geniculate bodies and the inferior colliculi in Alzheimer's disease: a Golgi and electron microscope study. Acta Otolaryngol. 129(4), 416-418 (2009).
15. Baloyannis SJ. Morphological and morphometric alterations of Cajal-Retzius cells in early cases of Alzheimer's disease: a Golgi and electron microscope study. Intern. J. Neurosci. 115, 965-980 (2005).
16. del Valle J, Bayod S, Camins A et al. Dendritic spine abnormalities in hippocampal CA1 pyramidal neurons underlying memory deficits in the SAMP8 mouse model of Alzheimer's disease. J. Alzheimers Dis. 32(1), 233-240 (2012).
17. Zhou Y, Luo Y, Dai J. Axonal and dendritic changes are associated with diabetic encephalopathy in rats: an important risk factor for Alzheimer's disease. J. Alzheimers Dis. 34(4), 937-947 (2013).
18. Spiga S, Acquas E, Puddu MC, Mulas G, Lintas A, Diana M. Simultaneous Golgi-Cox and immunofluorescence using confocal microscopy. Brain Struct. Funct. 216(3), 171-182 (2011).
19. Baloyannis SJ. Mitochondrial alterations in Alzheimer's disease. J. Alzh. Dis. 9(2), 119-126 (2006).
20. Baloyannis S. The Golgi apparatus of Purkinje cells in Alzheimer's disease. In: Neuropathology Back to the Roots. Bohl J (Ed.). Shaker Vertag, Aachen, Germany, 1-10 (2002).
21. Calkins MJ, Manczak M, Mao P, Shirendeb U, Reddy PH. Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease. Hum. Mol. Genet. 20(23), 4515-4529 (2011).
22. Zempel H, Thies E, Mandelkow E, Mandelkow EM. Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous tau into dendrites, tau phosphorylation, and destruction of microtubules and spines. J. Neurosci. 30(36), 11938-11950 (2010).
23. Adalbert R, Coleman MP. Axon pathology in age-related neurodegenerative disorders. Neuropathol. Appl. Neurobiol. doi:10.1111/j.1365-2990.2012.01308.x. (2012) (Epub ahead of print).
24. Blazquez-Llorca L, Merchán-Pérez A, Rodríguez R, Gascón J, Defelipe J. FIB/SEM technology and Alzheimer's disease: three-dimensional analysis of human cortical synapses. J. Alzheimers Dis. 34(4), 995-1013 (2013).
25. Mavroudis I, Petrides F, Manani M et al. Dendritic and spinal alterations of the spiny stellate cells of the human visual cortex during normal aging. Folia Neuropathol. 50(3), 261-269 (2012).
26. Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. 82, 239-959 (1991).