A fishy conclusion regarding n-3 fatty acid supplementation in cancer patients

Clinical Nutrition

Volumn 32, Issue 3, 2013, Pages 466-467

  Murphy, Rachel A ^a   Clandinin, M Thomas ^a   Chu, Quincy S ^a   Arends, Jann ^b   Mazurak, Vera C ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Chemoresistance; Chemotherapy; Cisplatin; Humans; N 3 fatty acids; Tumor cells

Indexed keywords

DOCOSAHEXAENOIC ACID; FISH OIL; ICOSAPENTAENOIC ACID; OMEGA 3 FATTY ACID; PLATINUM DERIVATIVE;

APPETITE; ARTICLE; CACHEXIA; CANCER PATIENT; CANCER RESEARCH; CANCER THERAPY; DRUG CYTOTOXICITY; DRUG EFFICACY; HEALTH CARE QUALITY; HUMAN; LUNG CANCER; MALIGNANT NEOPLASTIC DISEASE; MUSCLE FUNCTION; MUSCLE MASS; NONHUMAN; PHYSICAL ACTIVITY; TREATMENT RESPONSE; VITAMIN SUPPLEMENTATION;

ANIMALS; DIETARY SUPPLEMENTS; DISEASE MODELS, ANIMAL; FATTY ACIDS, OMEGA-3; FISH OILS; HUMANS; NEOPLASMS; NUTRITIONAL REQUIREMENTS;

EID: 84877147621     PISSN: 02615614     EISSN: 15321983     Source Type: Journal    
DOI: 10.1016/j.clnu.2012.05.013     Document Type: Article

References (16)

1. Roodhart J.M.L., Daenen L.G.M., Stitger E.C.A., Prins H.-J., Gerrits J., Houthuijzen J.M., et al. Mesenchymal stem cells induce resistance to chemotherapy through the release of platinum-induced fatty acids. Cancer Cell 2011, 20:370-383.
2. Murphy R.A., Yeung E., Mazurak V.C., Mourtzakis M. Influence of eicosapentaenoic acid supplementation on lean body mass in cancer cachexia. Br J Cancer 2011, 105:1469-1473.
3. Ries A., Trottenberg P., Elsner F., Stiel S., Haugen D., Kaasa S., et al. A systematic review on the role of fish oil for the treatment of cachexia in advanced cancer: an EPCRC cachexia guidelines project. Palliat Med Aug 24 2011, 10.1177/0269216311418709.
4. Murphy R.A., Mourtzakis M., Mazurak V.C. N-3 polyunsaturated fatty acids: the potential role for supplementation in cancer. Curr Opin Clin Nutr Metab Care 2012 Feb 23, [Epub ahead of print].
5. van der Meij B.S., Langius J.A., Spreeuwenberg M.D., Slootmaker S.M., Paul M.A., Smit E.F., et al. Oral nutritional supplements containing n-3 polyunsaturated fatty acids affect quality of life and functional status in lung cancer patients during multimodality treatment: an RCT. Eur J Clin Nutr 2012, 66:399-404.
6. Murphy R.A., Mourtzakis M., Reiman T., Chu Q., Baracos V.E., Mazurak V.C. Supplementation with fish oil increases first-line chemotherapy efficacy in patients with advanced non-small cell lung cancer. Cancer 2011, 117:3774-3780.
7. Bougnoux P., Hajjaji N., Ferrasson M.N., Giraudeau B., Couet C., Le Floch O. Improving outcome of chemotherapy of metastatic breast cancer by docosahexaenoic acid: a phase II trial. Br J Cancer 2009, 101:1978-1985.
8. Ma D.W.L., Mazurak V.C., Baracos V.E. N-3 fatty acids and Cancer Progression. Nutr Res Rev 2004, 17:177-192.
9. Granci V., Dupertuis Y.M., Pichard C. Angiogenesis as a potential target of pharmaconutrients in cancer therapy. Curr Opin Clin Nutr Metab Care 2010, 13:417-422.
10. Xue H., Sawyer M.B., Wischmeyer P.E., Baracos V.E. Nutrition modulation of gastrointestinal toxicity related to cancer chemotherapy: from preclinical findings to clinical strategy. JPEN J Parenter Enteral Nutr 2011, 35:74-90.
11. Dupertuis Yves M., Meguid M.M., Pichard C. Colon cancer therapy, new perspectives on of nutritional manipulations using polyunsaturated fatty acids. Curr Opin Clin Nutr Metab Care 2007, 10:427-432.
12. Murphy R.A., Mourtzakis M., Reiman T., Chu Q., Mazurak V.C. Nutritional intervention with fish oil provides a benefit over standard of care on weight, and skeletal muscle mass in non-small cell lung cancer patients receiving chemotherapy. Cancer 2011, 117:1775-1782.
13. van der Meij B.S., Langius J.A., Smit E.F., Spreeuwenberg M.D., von Blomberg B.M., Heijboer A.C., et al. Oral nutritional supplements containing (n-3) polyunsaturated fatty acids affect the nutritional status of patients with stage III nonsmall cell lung cancer during multimodality treatment. J Nutr 2010, 140:1774-1780.
14. Fearon K.C., Von Meyenfeldt M.F., Moses A.G., Van Geenen R., Roy A., Gouma D.J., et al. Effect of a protein and energy dense N-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia: a randomised double blind trial. Gut 2003, 52:1479-1486.
15. Uramoto H., Nakanishi R., Nagashima A., Uchiyama A., Inoue M., Osaki T., et al. A randomized phase II trial of adjuvant chemotherapy with bi-weekly carboplatin plus paclitaxel versus carboplatin plus gemcitabine in patients with completely resected non-small cell lung cancer. Anticancer Res 2010, 30:4695-4699.
16. Azzoli C.G., Baker S., Temin S., Pao W., Aliff T., Brahmer J., et al. American society of clinical oncology clinical practice guideline update on chemotherapy for stage IV non-small-cell lung cancer. J Clin Oncol 2009, 27:6251-6266. American Society of clinical Oncology.