Angiogenesis as a potential target of pharmaconutrients in cancer therapy

Current Opinion in Clinical Nutrition and Metabolic Care

Volumn 13, Issue 4, 2010, Pages 417-422

  Granci, Virginie ^a   Dupertuis, Yves M ^a   Pichard, Claude ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

angiogenesis; cancer; cell migration; metastasis; pharmaconutrients

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOSTATIN; ANTHOCYANIN; ANTHRACYCLINE; APOCININ; ARACHIDONIC ACID; CURCUMIN; DOCETAXEL; DOCOSAHEXAENOIC ACID; DOXORUBICIN; ENDOSTATIN; EPIGALLOCATECHIN GALLATE; FATTY ACID; FLUOROURACIL; GEMCITABINE; INTERFERON; INTERLEUKIN 12; INTERLEUKIN 4; ISOFLAVONOID; ISOLIQUIRITIGENIN; NATURAL PRODUCT; OMEGA 3 FATTY ACID; OXALIPLATIN; OXYGEN; POLYPHENOL; QUERCETIN; RESVERATROL; TISSUE INHIBITOR OF METALLOPROTEINASE; UNCLASSIFIED DRUG; VANILLIN;

ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; BLOOD VESSEL; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER INVASION; CANCER RESEARCH; CANCER THERAPY; CARCINOGENESIS; DIET SUPPLEMENTATION; FOOD INTAKE; HUMAN; NONHUMAN; NUTRIENT; REVIEW;

ANGIOGENESIS INHIBITORS; DIETARY SUPPLEMENTS; FATTY ACIDS, OMEGA-3; FLAVONOIDS; HUMANS; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; PHENOLS; PHYTOTHERAPY; PLANT EXTRACTS; SIGNAL TRANSDUCTION;

EID: 77954348374     PISSN: 13631950     EISSN: 14736519     Source Type: Journal    
DOI: 10.1097/MCO.0b013e3283392656     Document Type: Review

References (41)

1. Jones NE, Heyland DK. Pharmaconutrition: a new emerging paradigm. Curr Opin Gastroenterol 2008; 24:215-222.
2. Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971; 285:1182-1186.
3. Red-Horse K, Crawford Y, Shojaei F, et al. Endothelium-microenvironment interactions in the developing embryo and in the adult. Dev Cell 2007; 12:181-194.
4. Perrone G, Vincenzi B, Santini D, et al. Correlation of p53 and bcl-2 expression with vascular endothelial growth factor (VEGF), microvessel density (MVD) and clinico-pathological features in colon cancer. Cancer Lett 2004; 208:227-234.
5. Cheresh DA, Stupack DG. Regulation of angiogenesis: apoptotic cues from the ECM. Oncogene 2008; 27:6285-6298.
6. Raffetto JD, Khalil RA. Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease. Biochem Pharmacol 2008; 75: 346-359.
7. Chrzanowska-Wodnicka M, Kraus AE, Gale D, et al. Defective angiogenesis, endothelial migration, proliferation, and MAPK signaling in Rap1b-deficient mice. Blood 2008; 111:2647-2656.
8. Korpisalo P, Karvinen H, Rissanen TT, et al. Vascular endothelial growth factor-A and platelet-derived growth factor-B combination gene therapy prolongs angiogenic effects via recruitment of interstitial mononuclear cells and paracrine effects rather than improved pericyte coverage of angiogenic vessels. Circ Res 2008; 103:1092-1099.
9. Popkin BM. Understanding global nutrition dynamics as a step towards controlling cancer incidence. Nat Rev Cancer 2007; 7:61-67.
10. Aggarwal BB, Van Kuiken ME, Iyer LH, et al. Molecular targets of nutraceu-ticals derived from dietary spices: potential role in suppression of inflammation and tumorigenesis. Exp Biol Med (Maywood) 2009; 234:825-849.
11. Mazzio EA, Soliman KF. In-vitro screening for the tumoricidal properties of international medicinal herbs. Phytother Res 2009; 23:385-398.
12. Berquin IM, Min Y, Wu R, et al. Modulation of prostate cancer genetic risk by omega-3 and omega-6 fatty acids. J Clin Invest 2007; 117:1866-1875.
13. Pan MH, Ho CT. Chemopreventive effects of natural dietary compounds on cancer development. Chem Soc Rev 2008; 37:2558-2574.
14. Pohland T, Wagner S, Mahyar-Roemer M, et al. Bax and Bak are the critical complementary effectors of colorectal cancer cell apoptosis by chemopreventive resveratrol. Anticancer Drugs 2006; 17:471-478.
15. Toit-Kohn JL, Louw L, Engelbrecht AM. Docosahexaenoic acid induces apoptosis in colorectal carcinoma cells by modulating the PI3 kinase and p38 MAPK pathways. J Nutr Biochem 2009; 20:106-114.
16. Hardman WE, AvulaCP, Fernandes G, et al. Three-percentage dietary fish oil concentrate increased efficacy of doxorubicin against MDA-MB 231 breast cancer xenografts. Clin Cancer Res 2001; 7:2041-2049.
17. Sala-Vila A, Folkes J, Calder PC. The effect of three lipid emulsions differing in fatty acid composition on growth, apoptosis and cell cycle arrest in the HT-29 colorectal cancer cell line. Clin Nutr 2009 [Epub ahead of print]
18. Yang KC, Tsai CY, Wang YJ, et al. Apple polyphenol phloretin potentiates the anticancer actions of paclitaxel through induction of apoptosis in human hep G2 cells. Mol Carcinog 2009; 48:420-431.
19. Zhuo Z, Zhang L, Mu Q, et al. The effect of combination treatment with docosahexaenoic acid and 5-fluorouracil on the mRNA expression of apop-tosis-related genes, including the novel gene BCL2L12, in gastric cancer cells. In Vitro Cell Dev Biol Anim 2009; 45:69-74.
20. Lang M, Henson R, Braconi C, et al. Epigallocatechin-gallate modulates chemotherapy-induced apoptosis in human cholangiocarcinoma cells. Liver Int 2009; 29:670-677.
21. Kim YH, Lee DH, Jeong JH, et al. Quercetin augments TRAIL-induced apoptotic death: involvement of the ERK signal transduction pathway. Bio-chem Pharmacol 2008; 75:1946-1958.
22. Du B, Jiang L, Xia Q, et al. Synergistic inhibitory effects of curcumin and 5-fluorouracil on the growth of the human colon cancer cell line HT-29. Chemotherapy 2006; 52:23-28.
23. Shaikh IA, Brown I, Schofield AC, et al. Docosahexaenoic acid enhances the efficacy of docetaxel in prostate cancer cells by modulation of apoptosis: the role of genes associated with the NF-kappaB pathway. Prostate 2008; 68:1635-1646.
24. Dann JM, Sykes PH, Mason DR, et al. Regulation of vascular endothelial growth factor in endometrial tumour cells by resveratrol and EGCG. Gynecol Oncol 2009; 113:374-378.
25. Liu Y, Veena CK, Morgan JB, et al. Methylalpinumisoflavone inhibits hypoxia-inducible factor-1 (HIF-1) activation by simultaneously targeting multiple pathways. J Biol Chem 2009; 284:5859-5868.
26. Kwon GT, Cho HJ, Chung WY, et al. Isoliquiritigenin inhibits migration and invasion of prostate cancer cells: possible mediation by decreased JNK/AP-1 signaling. J Nutr Biochem 2009; 20:663-676.
27. Lin SS, Lai KC, Hsu SC, et al. Curcumin inhibits the migration and invasion of human A549 lung cancer cells through the inhibition of matrix metalloprotei-nase-2 and metalloproteinase-9 and vascular endothelial growth factor (VEGF). Cancer Lett 2009; 285:127-133.
28. Yoysungnoen P, Wirachwong P, Bhattarakosol P, et al. Effects of curcumin on tumor angiogenesis and biomarkers, COX-2 and VEGF, in hepatocellular carcinoma cell-implanted nude mice. Clin Hemorheol Microcirc 2006; 34:109-115.
29. Brown MD, Hart C, Gazi E, etal. Influence of omega-6 PUFAarachidonic Acid and Bone Marrow Adipocytes on Metastatic Spread from Prostate Cancer. Br J Cancer 2010; 102:403-413.
30. Calviello G, Di Nicuolo F, Gragnoli S, et al. n-3 PUFAs reduce VEGF expression in human colon cancer cells modulating the COX-2/PGE2 induced ERK-1 and ERK-2 and HIF-1 alpha induction pathway. Carcinogenesis 2004; 25:2303-2310.
31. Denkins Y, Kempf D, Ferniz M, et al. Role of omega-3 polyunsaturated fatty acids on cyclooxygenase-2 metabolism in brain-metastatic melanoma. J Lipid Res 2005; 46:1278-1284.
32. Calviello G, Resci F, Serini S, et al. Docosahexaenoic acid induces protea-some-dependent degradation of beta-catenin, downregulation of surviving and apoptosis in human colorectal cancer cells not expressing COX-2. Carcinogenesis 2007; 28:1202-1209.
33. Altenburg JD, Siddiqui RA. Omega-3 polyunsaturated fatty acids downmo-dulate CXCR4 expression and function in MDA-MB-231 breast cancer cells. Mol Cancer Res 2009; 7:1013-1020.
34. Huang HP, Shih YW, Chang YC, et al. Chemoinhibitory effect of mulberry anthocyanins on melanoma metastasis involved in the Ras/PI3K pathway. J Agric Food Chem 2008; 56:9286-9293.
35. Lee SH, Cekanova M, Baek SJ. Multiple mechanisms are involved in 6-gingerol-induced cell growth arrest and apoptosis in human colorectal cancer cells. Mol Carcinog 2008; 47:197-208.
36. Lirdprapamongkol K, Kramb JP, Suthiphongchai T, et al. Vanillin suppresses metastatic potential of human cancer cells through PI3K inhibition and decreases angiogenesis in vivo. J Agric Food Chem 2009; 57:3055-3063.
37. Colas S, Maheo K, Denis F, et al. Sensitization by dietary docosahexaenoic acid of rat mammary carcinoma to anthracycline: a role for tumor vascularization. Clin Cancer Res 2006; 12:5879-5886.
38. Siddiqui IA, Malik A, Adhami VM, et al. Green tea polyphenol EGCG sensitizes human prostate carcinoma LNCaP cells to TRAIL-mediated apoptosis and synergistically inhibits biomarkers associated with angiogenesis and metastasis. Oncogene 2008; 27:2055-2063.
39. Du G, Lin H, Wang M, et al. Quercetin greatly improved therapeutic index of doxorubicin against 4T1 breast cancer by its opposing effects on HIF-1alpha in tumor and normal cells. Cancer Chemother Pharmacol 2010; 65:277-287.
40. KunnumakkaraAB, GuhaS, Krishnan S, et al. Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products. Cancer Res 2007; 67:3853-3861.
41. Tharakan ST, Inamoto T, Sung B, et al. Curcumin potentiates the antitumor effects of gemcitabine in an orthotopic model of human bladder cancer through suppression of proliferative and angiogenic biomarkers. Biochem Pharmacol 2010; 79:218-228.