Isoflurane pretreatment ameliorates postischemic neurologic dysfunction and preserves hippocampal Ca2+/calmodulin-dependent protein kinase in a canine cardiac arrest model

Anesthesiology

Volumn 93, Issue 5, 2000, Pages 1285-1293

  Blanck, Thomas J J ^a,b,c   Haile, Michael ^a,b   Xu, Fang ^a   Zhang, Jin ^a   Heerdt, Paul ^b   Veselis, Robert A ^b   Beckman, James ^b   Kang, Richard ^b   Adamo, Anna ^b   Hemmings, Hugh ^b  

^a Hospital for Special Surgery   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c HOSPITAL FOR SPECIAL SURGERY   (United States)

Author keywords

Global cerebral ischemia; Neuronal calcium; Resuscitation; Volatile anesthetic

Indexed keywords

CALCIUM ION; ISOFLURANE; NEUROPROTECTIVE AGENT; PROTEIN KINASE (CALCIUM,CALMODULIN);

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CALCIUM TRANSPORT; CONTROLLED STUDY; DOG; DRUG EFFICACY; ENZYME ACTIVITY; HEART ARREST; HIPPOCAMPUS; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; SCORING SYSTEM;

EID: 0033763479     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-200011000-00023     Document Type: Article

References (33)

1. Stroke prevalence and mechanisms of cell death
2. Relationships between ions and energy metabolism: Cerebral calcium movements during ischaemia and subsequent recovery
3. Sodium, ATP, and intracellular pH transients during reversible complete ischemia of dog cerebrum
4. Alteration of voltage-dependent calcium channels in canine brain during global ischemia and reperfusion
5. Increased activation of L-type voltage-dependent calcium channels is associated with glycine enhancement of N-methyl-D-aspartate-stimulated dopamine release in global cerebral ischemia
6. Depression of calcium channel blocker binding to rat brain membranes by halothane
7. Halothane and isoflurane alter calcium dynamics in rat cerebrocortical dynaptosomes
8. Prevention of postischemic canine neurological injury through potentiation of brain energy metabolism by acetyl-L-carnitine
9. Cerebral preservation during cardiopulmonary resuscitation
10. A rapid method for isolation of synaptosomes on Percoll gradients
11. Measurement of protein using bicinchoninic acid
12. DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleus
13. 2+/calmodulin-dependent protein kinase II in rat ileal enterocytes
14. Effect of halothane on conventional protein kinase C translocation and down-regulation in rat cerebrocortical synaptosomes
15. 'Western blotting': Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to modified nitrocellulose and radiographic detection with antibody and radioiodinated protein A
16. Delay in cooling negates the beneficial effect of mild resuscitative cerebral hypothermia after cardiac arrest in dogs: A prospective, randomized study
17. Amelioration of brain damage after 12 minutes' cardiac arrest in dogs
18. Differential effects of anesthetic on outcome from near-complete but not incomplete global ischemia in the rat
19. Isoflurane delays but does not prevent cerebral infarction in rats subject to focal ischemia
20. The role of L-type voltage-dependent calcium channels in anesthetic depression of contractility
21. Isoflurane inhibits multiple voltage-gated calcium currents in hippocampal pyramidal neurons
22. 2+ transients
23. The multifunctional calcium/calmodulin-dependent protein kinase: From form to function
24. Synapsins as regulators of neurotransmitter release
25. 2+/calmodulin-dependent protein kinase II
26. 2+/calmodulin-dependent protein kinase II following spinal cord ischemia
27. Ischemia-induced neuronal damage: A role for calcium/calmodulin-dependent protein kinase II
28. Inhibition by volatile anesthetics of endogenous glutamate release from synaptosomes by a presynaptic mechanism
29. The effect of isoflurane on brain amino acid release and tissue content induced by energy deprivation
30. Effects of isoflurane and hypothermia on glutamate receptor-mediated calcium influx in brain slices
31. Hypothermia and isoflurane similarly inhibit glutamate release evoked by chemical anoxia in rat cortical brain slices
32. Effects of hypothermia, pentobarbital, and isoflurane on postdepolarization amino acid release during complete global cerebral ischemia
33. Isoflurane attenuates early neutrophil-independent hypoxia-reoxygenation injuries in the reperfused liver in fasted rats