Local and circulating levels of adipocytokines in obese and normal weight individuals with chronic periodontitis

Journal of Periodontology

Volumn 84, Issue 5, 2013, Pages 624-633

  Zimmermann, Glaucia Santos ^a,b   Bastos, Marta Ferreira ^a   Goncxalves, Tiago Eduardo Dias ^a   Chambrone, Leandro ^a   Duarte, Poliana Mendes ^a  

^a GUARULHOS UNIVERSITY   (Brazil)

^b FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

Adipokines; Adiponectin; Chronic periodontitis; Leptin; Obesity; Resistin

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; INTERLEUKIN 6; LEPTIN; RESISTIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ANALYSIS OF VARIANCE; ARTICLE; BLOOD; CASE CONTROL STUDY; CHEMISTRY; CHRONIC PERIODONTITIS; CROSS-SECTIONAL STUDY; FEMALE; GINGIVITIS; HUMAN; MALE; METABOLISM; MIDDLE AGED; OBESITY; PERIODONTAL POCKET; STATISTICAL MODEL;

ADIPOKINES; ADIPONECTIN; ADULT; AGED; ANALYSIS OF VARIANCE; CASE-CONTROL STUDIES; CHRONIC PERIODONTITIS; CROSS-SECTIONAL STUDIES; FEMALE; GINGIVAL CREVICULAR FLUID; HUMANS; INTERLEUKIN-6; LEPTIN; LOGISTIC MODELS; MALE; MIDDLE AGED; OBESITY; PERIODONTAL POCKET; RESISTIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84877120772     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2012.120254     Document Type: Article

References (43)

1. Ouchi N, Parker JL, Lugus JJ, Walsh K. Adipokines in inflammation and metabolic disease. Nat Rev Immunol 2011;11:85-97.
2. Chaffee BW, Weston SJ. Association between chronic periodontal disease and obesity: A systematic review and meta-Analysis. J Periodontol 2010;81:1708-1724.
3. Suvan J, D'Aiuto F, Moles DR, Petrie A, Donos N. Association between overweight/obesity and periodontitis in adults. A systematic review. Obes Rev 2011;12:e381-e404.
4. Wozniak SE, Gee LL, Wachtel MS, Frezza EE. Adipose tissue: The new endocrine organ A review article. Dig Dis Sci 2009;54:1847-1856.
5. Conde J, Scotece M, Gómez R, et al. Adipokines: Biofactors from white adipose tissue. A complex hub among inflammation, metabolism, and immunity. Biofactors 2011;37:413-420.
6. Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-A: Direct role in obesity-linked insulin resistance. Science 1993;259: 87-91.
7. Preshaw PM, Taylor JJ. How has research into cytokine interactions and their role in driving immune responses impacted our understanding of periodontitis? J Clin Periodontol 2011;38 (Suppl. 11):60-84.
8. Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature 1998;395:763-770.
9. Lord GM, Matarese G, Howard JK, Baker RJ, Bloom SR, Lechler RI. Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression. Nature 1998;394:897-901.
10. Kiguchi N, Maeda T, Kobayashi Y, Fukazawa Y, Kishioka S. Leptin enhances CC-chemokine ligand expression in cultured murine macrophage. Biochem Biophys Res Commun 2009;384:311-315.
11. Johnson RB, Serio FG. Leptin within healthy and diseased human gingiva. J Periodontol 2001;72: 1254-1257.
12. Karthikeyan BV, Pradeep AR. Gingival crevicular fluid and serum leptin: Their relationship to periodontal health and disease. J Clin Periodontol 2007;34:467-472.
13. Bokarewa M, Nagaev I, Dahlberg L, Smith U, Tarkowski A. Resistin, an adipokine with potent proinflammatory properties. J Immunol 2005;174:5789-5795.
14. Kawanami D, Maemura K, Takeda N, et al. Direct reciprocal effects of resistin and adiponectin on vascular endothelial cells: A new insight into adipocytokineendothelial cell interactions. Biochem Biophys Res Commun 2004;314:415-419.
15. Saito T, Yamaguchi N, Shimazaki Y, et al. Serum levels of resistin and adiponectin in women with periodontitis: The Hisayama study. J Dent Res 2008;87:319-322.
16. Furugen R, Hayashida H, Yamaguchi N, et al. The relationship between periodontal condition and serum levels of resistin and adiponectin in elderly Japanese. J Periodontal Res 2008;43:556-562.
17. Ryo M, Nakamura T, Kihara S, et al. Adiponectin as a biomarker of the metabolic syndrome. Circ J 2004; 68:975-981.
18. Yamaguchi N, Hamachi T, Kamio N, et al. Expression levels of adiponectin receptors and periodontitis. J Periodontal Res 2010;45:296-300.
19. Dalla Vecchia CF, Susin C, Rosing CK, Oppermann RV, Albandar JM. Overweight and obesity as risk indicators for periodontitis in adults. J Periodontol 2005;76:1721-1728.
20. Pataro AL, Costa FO, Cortelli SC, Cortelli JR, Abreu MH, Costa JE. Association between severity of body mass index and periodontal condition in women. Clin Oral Investig 2012;16:727-734.
21. Santos VR, Ribeiro FV, Lima JA, Napimoga MH, Bastos MF, Duarte PM. Cytokine levels in sites of chronic periodontitis of poorly controlled and well-controlled type 2 diabetic subjects. J Clin Periodontol 2010;37: 1049-1058.
22. Ainamo J, Bay I. Problems and proposals for recording gingivitis and plaque. Int Dent J 1975;25:229-235.
23. World Health Organization. Waist Circumference and Waist-Hip Ratio: Report of aWHO Expert Consultation: Geneva, 2008, December: 1-47.
24. Armitage GC. Development of a classification system for periodontal diseases and conditions. Ann Periodontol 1999;4:1-6.
25. Shimada Y, Komatsu Y, Ikezawa-Suzuki I, Tai H, Sugita N, Yoshie H. The effect of periodontal treatment on serum leptin, interleukin-6, and C-reactive protein. J Periodontol 2010;81:1118-1123.
26. Karthikeyan BV, Pradeep AR. Leptin levels in gingival crevicular fluid in periodontal health and disease. J Periodontal Res 2007;42:300-304.
27. Lear SA, James PT, Ko GT, Kumanyika S. Appropriateness of waist circumference and waist-to-hip ratio cutoffs for different ethnic groups. Eur J Clin Nutr 2010; 64:42-61.
28. Nagano Y, Arishiro K, Uene M, et al. A low ratio of high molecular weight adiponectin to total adiponectin associates with periodontal status in middle-Aged men. Biomarkers 2011;16:106-111.
29. Kumada M, Kihara S, Ouchi N, et al. Adiponectin specifically increased tissue inhibitor of metalloproteinase-1 through interleukin-10 expression in human macrophages. Circulation 2004;109:2046-2049.
30. Liu ZW, Zhang N, Han QY, et al. Correlation of serum leptin levels with anthropometric and metabolic parameters and biochemical liver function in Chinese patients with chronic hepatitis C virus infection. World J Gastroenterol 2005;11:3357-3362.
31. Grunfeld C, Zhao C, Fuller J, et al. Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters. J Clin Invest 1996;97:2152-2157.
32. Kim SJ. Leptin potentiates Prevotella intermedia lipopolysaccharide- induced production of TNF-Alpha in monocyte-derived macrophages. J Periodontal Implant Sci 2010;40:119-124.
33. Tsigos C, Kyrou I, Chala E, et al. Circulating tumor necrosis factor alpha concentrations are higher in abdominal versus peripheral obesity. Metabolism 1999;48:1332-1335.
34. Ziccardi P, Nappo F, Giugliano G, et al. Reduction of inflammatory cytokine concentrations and improvement of endothelial functions in obese women after weight loss over one year. Circulation 2002;105:804-809.
35. Zuza EP, Barroso EM, Carrareto AL, et al. The role of obesity as a modifying factor in patients undergoing non-surgical periodontal therapy. J Periodontol 2011; 82:676-682.
36. Genco RJ, Grossi SG, Ho A, Nishimura F, Murayama Y. A proposed model linking inflammation to obesity, diabetes, and periodontal infections. J Periodontol 2005; 76(Suppl. 11)2075-2084.
37. Khanna S, Mali AM. Evaluation of tumor necrosis factor-A (TNF-A) levels in plasma and their correlation with periodontal status in obese and non-obese subjects. J Indian Soc Periodontol 2010;14:217-221.
38. Saxlin T, Suominen-Taipale L, Leiviska J, Jula A, Knuuttila M, Ylostalo P. Role of serum cytokines tumour necrosis factor-Alpha and interleukin-6 in the association between body weight and periodontal infection. J Clin Periodontol 2009;36:100-105.
39. Nakajima T, Honda T, Domon H, et al. Periodontitisassociated up-regulation of systemic inflammatory mediator level may increase the risk of coronary heart disease. J Periodontal Res 2010;45:116-122.
40. Kurtisx B, Tuter G, Serdar M, et al. Gingival crevicular fluid levels of monocyte chemoattractant protein-1 and tumor necrosis factor-Alpha in patients with chronic and aggressive periodontitis. J Periodontol 2005;76: 1849-1855.
41. Rossomando EF, Kennedy JE, Hadjimichael J. Tumour necrosis factor alpha in gingival crevicular fluid as a possible indicator of periodontal disease in humans. Arch Oral Biol 1990;35:431-434.
42. Lundin M. Yucel-LindbergT, Dahllof G, Marcus C, Modéer T. Correlation between TNFalpha in gingival crevicular fluid and body mass index in obese subjects. Acta Odontol Scand 2004;62:273-277.
43. Khosravi R, Tran SD, Lambert M, et al. Adiposity and gingival crevicular fluid tumour necrosis factoralpha levels in children. J Clin Periodontol 2009;36: 301-307.