Role of serum cytokines tumour necrosis factor-α and interleukin-6 in the association between body weight and periodontal infection

Journal of Clinical Periodontology

Volumn 36, Issue 2, 2009, Pages 100-105

  Saxlin, Tuomas ^a   Suominen Taipale, Liisa ^b   Leiviskä, Jaana ^b   Jula, Antti ^b   Knuuttila, Matti ^c   Ylöstalo, Pekka ^a  

^a UNIVERSITY OF OULU   (Finland)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^c OULU UNIVERSITY HOSPITAL   (Finland)

Author keywords

Body weight; IL 6; Periodontal infection; TNF

Indexed keywords

INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BACTERIAL INFECTION; BLOOD; BODY WEIGHT; CHRONIC PERIODONTITIS; FEMALE; HUMAN; MALE; MIDDLE AGED; PERIODONTITIS; REGRESSION ANALYSIS;

BACTERIAL INFECTIONS; BODY WEIGHT; CHRONIC PERIODONTITIS; FEMALE; HUMANS; INTERLEUKIN-6; MALE; MIDDLE AGED; PERIODONTAL POCKET; REGRESSION ANALYSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 58849156540     PISSN: 03036979     EISSN: 1600051X     Source Type: Journal    
DOI: 10.1111/j.1600-051X.2008.01350.x     Document Type: Article

References (28)

1. Al-Zahrani, M. S., Bissada, N. F. Borawski, E. A. (2003) Obesity and periodontal disease in young, middle-aged, and older adults. Journal of Periodontology 74, 610 615.
2. Bartold, P. M., Marshall, R. I. Haynes, D. R. (2005) Periodontitis and rheumatoid arthritis: a review. Journal of Periodontology 76, 2066 2074.
3. Dalla Vecchia, C. F., Susin, C., Rösing, C. K., Oppermann, R. V. Albandar, J. M. (2005) Overweight and obesity as risk indicators for periodontitis in adults. Journal of Periodontology 76, 1721 1728.
4. Fantuzzi, G. (2005) Adipose tissue, adipokines and inflammation. Journal of Allergy and Clinical Immunology 115, 911 919.
5. Gemmell, E., Marshall, R. I. Seymour, G. J. (1997) Cytokines and prostaglandins in immune homeostasis and tissue destruction in periodontal disease. Periodontology 2000 14, 112 143.
6. Genco, R. J., Grossi, S. G., Ho, A., Nishimura, F. Murayama, Y. (2005) A proposed model linking inflammation to obesity, diabetes and periodontal infections. Journal of Periodontology 76, 2075 2084.
7. Graves, D. T. (1999) The potential role of chemokines and inflammatory cytokines in periodontal disease progression. Clinical Infectious Diseases 28, 482 490.
8. Hujoel, P. P., Drangsholt, M., Spiekerman, C. DeRoen, T. A. (2002) Periodontitis-systemic disease associations in the presence of smoking - causal or coincidental? Periodontology 2000 30, 51 60.
9. Johnson, R. B. Serio, F. G. (2001) Leptin within healthy and diseased human gingiva. Journal of Periodontology 72, 1254 1257.
10. Karthikeyan, B. V. Pradeep, A. R. (2007) Leptin levels in gingival crevicular fluid in periodontal health and disease. Journal of Periodontal Research 42, 300 304.
11. Kinnby, B., Lindberg, P., Lecander, I. Matsson, L. (1999) Localization of plasminogen activators and plasminogen activator inhibitors in human gingival tissues demonstrated by immunohistochemistry and in situ hybridization. Archives of Oral Biology 44, 1027 1034.
12. Lundin, M., Yucel-Linberg, T., Dahllöf, G., Marcus, C. Modeer, T. (2004) Correlation between TNFa in gingival crevicular fluid and body mass index in obese subjects. Acta Odontologica Scandinavica 62, 273 277.
13. Mercado, F. B., Marshall, R. I. Bartold, P. M. (2003) Inter-relationships between rheumatoid arthritis and periodontal disease. Journal of Clinical Periodontology 30, 761 772.
14. Nishida, N., Tanaka, M., Hayashi, N., Nagata, H., Takeshita, T., Nakayama, K., Morimoto, K. Shizukuishi, S. (2005) Determination of smoking and obesity as periodontitis risks using the classification and regression tree method. Journal of Periodontology 76, 923 928.
15. Nishimura, F. Murayama, Y. (2001) Periodontal inflammation and insulin resistance - lessons from obesity. Journal of Dental Research 80, 1690 1694.
16. Page, R. (1991) The role of inflammatory mediators in the pathogenesis of periodontal disease. Journal of Periodontal Research 26, 230 242.
17. Park, J. Y. Pillinger, M. H. (2007) Interleukin-6 in the pathogenesis of rheumatoid arthritis. Bulletin of the NYU Hospital for Joint Diseases 65 (Suppl. 1), S4 S10.
18. Preshaw, P. M., Foster, N. Taylor, J. J. (2007) Cross-susceptibility between periodontal disease and type 2 diabetes mellitus: an immunobiological perspective. Periodontology 2000 45, 138 157.
19. Reeves, A. F., Rees, J. M., Schiff, M. Hujoel, P. P. (2006) Total body weight and waist circumference associated with chronic periodontitis among adolescents in the United States. Archives of Pediatrics and Adolescents Medicine 160, 894 899.
20. Ritchie, C. S. (2007) Obesity and periodontal disease. Periodontology 2000 44, 154 163.
21. Saito, T. Shimazaki, Y. (2007) Metabolic disorders related to obesity and periodontal disease. Periodontology 2000 43, 254 266.
22. Saito, T., Shimazaki, Y., Koga, T., Tsuzuki, M. Ohshima, A. (2001) Relationship between upper body obesity and periodontitis. Journal of Dental Research 80, 1631 1636.
23. Saxlin, T., Suominen-Taipale, L., Kattainen, A., Marniemi, J., Knuuttila, M. Ylöstalo, P. (2008) Association between serum lipid levels and periodontal infection. Journal of Clinical Periodontology, 35, 1040 1047.
24. Shimomura, I., Funahashi, T., Takahashi, M., Maeda, K., Kotani, K., Nakamura, T., Yamashita, S., Miura, M., Fukuda, Y., Takemura, K., Tokunaga, K. Matsuzava, Y. (1996) Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity. Nature Medicine 2, 800 803.
25. Stumvoll, M., Goldstein, B. J. van Haeften, T. W. (2005) Type 2 diabetes: principles of pathogenesis and therapy. Lancet 365, 1333 1346.
26. Vehkalahti, M., Knuuttila, M. Hausen, H. (2004) Kliinisten mittausten laadun varmistaminen (Quality assurance of clinical examinations). In : Suominen-Taipale, L., Nordblad, A., Vehkalahti, M. Aromaa, A. (eds). Suomalaisten Aikuisten Suunterveys, Terveys 2000 - Tutkimus (Oral Health of Finnish Adults, Health 2000 Health Examination Survey), pp. 24 32. Helsinki : Publications of the National Public Health Institute.
27. Wood, N., Johnson, R. B. Streckfus, C. F. (2003) Comparison of body composition and periodontal disease using nutritional assessment techniques: third National Health and Nutrition Examination Survey (NHANES III). Journal of Clinical Periodontology 30, 321 327.
28. Ziccardi, P., Nappo, F., Giugliano, G., Esposito, K., Marfella, R., Cioffi, M., D'Andrea, F., Molinari, A. M. Giugliano, D. (2002) Reduction of inflammatory cytokine concentrations and improvement of endothelial functions in obese women after weight loss over one year. Circulation 105, 804 809.