메뉴 건너뛰기




Volumn 168, Issue 5, 2013, Pages 665-674

Efficacy of everolimus in patients with metastatic insulinoma and refractory hypoglycemia

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; CYTOTOXIC AGENT; DACARBAZINE; DIAZOXIDE; DOXORUBICIN; EPIRUBICIN; EVEROLIMUS; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; GLUCOSE; INTERFERON; OCTREOTIDE; OXALIPLATIN; STREPTOZOCIN; SUNITINIB;

EID: 84877120580     PISSN: 08044643     EISSN: 1479683X     Source Type: Journal    
DOI: 10.1530/EJE-12-1101     Document Type: Article
Times cited : (85)

References (43)
  • 1
    • 0032434534 scopus 로고    scopus 로고
    • Insulinoma/hypoglycemic syndrome: A statistical evaluation of 1085 reported cases of a Japanese series
    • Soga J, Yakuwa Y & Osaka M. Insulinoma/hypoglycemic syndrome: a statistical evaluation of 1085 reported cases of a Japanese series. Journal of Experimental and Clinical Cancer Research 1998 17 379-388.
    • (1998) Journal of Experimental and Clinical Cancer Research , vol.17 , pp. 379-388
    • Soga, J.1    Yakuwa, Y.2    Osaka, M.3
  • 6
    • 4043171462 scopus 로고    scopus 로고
    • Upstream and downstream of mTOR
    • (doi:10.1101/gad. 1212704)
    • Hay N & Sonenberg N. Upstream and downstream of mTOR. Genes and Development 2004 18 1926-1945. (doi:10.1101/gad. 1212704)
    • (2004) Genes and Development , vol.18 , pp. 1926-1945
    • Hay, N.1    Sonenberg, N.2
  • 9
    • 73949088959 scopus 로고    scopus 로고
    • Daily oral everolimus activity in patients with metastatic pancreatic neuroendocrine tumors after failure of cytotoxic chemotherapy: A phase II trial
    • (doi:10.1200/JCO.2009.24.2669)
    • Yao JC, Lombard-Bohas C, Baudin E., Kvols LK, Rougier P, Ruszniewski P, Hoosen S., St Peter J, Haas T, Lebwohl D et al. Daily oral everolimus activity in patients with metastatic pancreatic neuroendocrine tumors after failure of cytotoxic chemotherapy: a phase II trial. Journal of Clinical Oncology 2010 28 69-76. (doi:10.1200/JCO.2009.24.2669)
    • (2010) Journal of Clinical Oncology , vol.28 , pp. 69-76
    • Yao, J.C.1    Lombard-Bohas, C.2    Baudin, E.3    Kvols, L.K.4    Rougier, P.5    Ruszniewski, P.6    Hoosen, S.7    St Peter, J.8    Haas, T.9    Lebwohl, D.10
  • 10
    • 67349127898 scopus 로고    scopus 로고
    • The emerging safety profile of mTOR inhibitors, a novel class of anticancer agents
    • (doi:10.1007/s11523-009-0107-z)
    • Sankhala K, Mita A, Kelly K., Mahalingam D, Giles F & Mita M. The emerging safety profile of mTOR inhibitors, a novel class of anticancer agents. Targeted Oncology 2009 4 135-142. (doi:10.1007/s11523-009-0107-z)
    • (2009) Targeted Oncology , vol.4 , pp. 135-142
    • Sankhala, K.1    Mita, A.2    Kelly, K.3    Mahalingam, D.4    Giles, F.5    Mita, M.6
  • 11
    • 69949100179 scopus 로고    scopus 로고
    • Successful control of intractable hypoglycemia using rapamycin in an 86-year-old man with a pancreatic insulin-secreting islet cell tumor and metastases
    • (doi:10.1210/jc.2009-0788)
    • Bourcier ME, Sherrod A, DiGuardo M & Vinik AI. Successful control of intractable hypoglycemia using rapamycin in an 86-year-old man with a pancreatic insulin-secreting islet cell tumor and metastases. Journal of Clinical Endocrinology and Metabolism 2009 94 3157-3162. (doi:10.1210/jc.2009-0788)
    • (2009) Journal of Clinical Endocrinology and Metabolism , vol.94 , pp. 3157-3162
    • Bourcier, M.E.1    Sherrod, A.2    DiGuardo, M.3    Vinik, A.I.4
  • 12
    • 1542398693 scopus 로고    scopus 로고
    • Randomized phase II study of multiple dose levels of CCI-779, a novel Mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma
    • (doi:10.1200/JCO.2004.08.185)
    • Atkins MB, Hidalgo M, Stadler W.M., Logan TF, Dutcher JP, Hudes GR, Park Y, Liou S-H, Marshall B. Boni JP et al. Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma. Journal of Clinical Oncology 2004 22 909-918. (doi:10.1200/JCO.2004.08.185)
    • (2004) Journal of Clinical Oncology , vol.22 , pp. 909-918
    • Atkins, M.B.1    Hidalgo, M.2    Stadler, W.M.3    Logan, T.F.4    Dutcher, J.P.5    Hudes, G.R.6    Park, Y.7    Liou, S.-H.8    Marshall, B.9    Boni, J.P.10
  • 15
    • 0033525754 scopus 로고    scopus 로고
    • Insulin-stimulated insulin secretion in single pancreatic b cells
    • (doi:10.1074/jbc.274.10.6360)
    • Aspinwall CA, Lakey JR & Kennedy RT. Insulin-stimulated insulin secretion in single pancreatic b cells. Journal of Biological Chemistry 1999 274 6360-6365. (doi:10.1074/jbc.274.10.6360)
    • (1999) Journal of Biological Chemistry , vol.274 , pp. 6360-6365
    • Aspinwall, C.A.1    Lakey, J.R.2    Kennedy, R.T.3
  • 16
    • 0032061042 scopus 로고    scopus 로고
    • Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways
    • (doi:10.1016/S1097-2765 (00)80093-3)
    • Leibiger IB, Leibiger B, Moede T & Berggren PO. Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways. Molecular Cell 1998 1 933-938. (doi:10.1016/S1097-2765 (00)80093-3)
    • (1998) Molecular Cell , vol.1 , pp. 933-938
    • Leibiger, I.B.1    Leibiger, B.2    Moede, T.3    Berggren, P.O.4
  • 17
    • 0035663898 scopus 로고    scopus 로고
    • Insulin release and suppression by tacrolimus, rapamycin and cyclosporin A are through regulation of the ATP-sensitive potassium channel
    • (doi:10.1046/ j.1463-1326.2001.00150.x)
    • Fuhrer DK, Kobayashi M & Jiang H. Insulin release and suppression by tacrolimus, rapamycin and cyclosporin A are through regulation of the ATP-sensitive potassium channel. Diabetes, Obesity & Metabolism 2001 3 393-402. (doi:10.1046/ j.1463-1326.2001.00150.x)
    • (2001) Diabetes, Obesity & Metabolism , vol.3 , pp. 393-402
    • Fuhrer, D.K.1    Kobayashi, M.2    Jiang, H.3
  • 18
    • 33746488875 scopus 로고    scopus 로고
    • Chronic inhibition of Mammalian target of rapamycin signaling downregulates insulin receptor substrates 1 and 2 and AKT activation: A crossroad between cancer and diabetes?
    • (doi:10.1681/ASN.2006030196)
    • Di Paolo S., Teutonico A, Leogrande D., Capobianco C & Schena PF. Chronic inhibition of mammalian target of rapamycin signaling downregulates insulin receptor substrates 1 and 2 and AKT activation: a crossroad between cancer and diabetes? Journal of the American Society of Nephrology 2006 17 2236-2244. (doi:10.1681/ASN.2006030196)
    • (2006) Journal of the American Society of Nephrology , vol.17 , pp. 2236-2244
    • Di Paolo, S.1    Teutonico, A.2    Leogrande, D.3    Capobianco, C.4    Schena, P.F.5
  • 19
    • 42449104351 scopus 로고    scopus 로고
    • MTOR inhibition by rapamycin prevents b-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes
    • (doi:10.2337/db07-0922)
    • Fraenkel M, Ketzinel-Gilad M, Ariav Y., Pappo O, Karaca M, Castel J., Berthault M-F, Magnan C, Cerasi E, Kaiser N et al. mTOR inhibition by rapamycin prevents b-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes. Diabetes 2008 57 945-957. (doi:10.2337/db07-0922)
    • (2008) Diabetes , vol.57 , pp. 945-957
    • Fraenkel, M.1    Ketzinel-Gilad, M.2    Ariav, Y.3    Pappo, O.4    Karaca, M.5    Castel, J.6    Berthault, M.-F.7    Magnan, C.8    Cerasi, E.9    Kaiser, N.10
  • 20
    • 58149385408 scopus 로고    scopus 로고
    • Glycemic control in patients with insulinoma treated with everolimus
    • (doi:10.1056/NEJMc0806740)
    • Kulke MH, Bergsland EK & Yao JC. Glycemic control in patients with insulinoma treated with everolimus. New England Journal of Medicine 2009 360 195-197. (doi:10.1056/NEJMc0806740)
    • (2009) New England Journal of Medicine , vol.360 , pp. 195-197
    • Kulke, M.H.1    Bergsland, E.K.2    Yao, J.C.3
  • 21
    • 77951654565 scopus 로고    scopus 로고
    • Therapies for the medical management of persistent hypoglycaemia in two cases of inoperable Malignant insulinoma
    • (doi:10.1530/EJE-09-1010)
    • Ong GSY, Henley DE, Hurley D, Turner J.H., Claringbold PG & Fegan PG. Therapies for the medical management of persistent hypoglycaemia in two cases of inoperable malignant insulinoma. European Journal of Endocrinology 2010 162 1001-1008. (doi:10.1530/EJE-09-1010)
    • (2010) European Journal of Endocrinology , vol.162 , pp. 1001-1008
    • Ong, G.S.Y.1    Henley, D.E.2    Hurley, D.3    Turner, J.H.4    Claringbold, P.G.5    Fegan, P.G.6
  • 22
    • 79959239083 scopus 로고    scopus 로고
    • Everolimus resolving hypoglycemia, producing hyperglycemia, and necessitating insulin use in a patient with diabetes and nonresectable Malignant insulinoma
    • (doi:10.4158/EP10282.CR)
    • Ferrer-García JC, Tolosa-Torréns M, Hernando-Meliá C, Arribas-Palomar L & Sánchez-Juan C. Everolimus resolving hypoglycemia, producing hyperglycemia, and necessitating insulin use in a patient with diabetes and nonresectable malignant insulinoma. Endocrine Practice 2011 17 e17-e20. (doi:10.4158/EP10282.CR)
    • (2011) Endocrine Practice , vol.17
    • Ferrer-García, J.C.1    Tolosa-Torréns, M.2    Hernando-Meliá, C.3    Arribas-Palomar, L.4    Sánchez-Juan, C.5
  • 23
    • 79959596899 scopus 로고    scopus 로고
    • Everolimus induces rapid plasma glucose Normalization in insulinoma patients by effects on tumor as well as normal tissues
    • (doi:10.1634/theoncologist.2010-0222)
    • Fiebrich H-B, Siemerink EJM, Brouwers AH, Links TP, Remkes W.S. Hospers GAP & De Vries EGE. Everolimus induces rapid plasma glucose normalization in insulinoma patients by effects on tumor as well as normal tissues. Oncologist 2011 16 783-787. (doi:10.1634/theoncologist.2010-0222)
    • (2011) Oncologist , vol.16 , pp. 783-787
    • Fiebrich, H.-B.1    Siemerink, E.J.M.2    Brouwers, A.H.3    Links, T.P.4    Remkes, W.S.5    Hospers, G.A.P.6    De Vries, E.G.E.7
  • 24
    • 78349309297 scopus 로고    scopus 로고
    • Management of intractable hypoglycemia with yttirum-90 radioembolization in a patient with Malignant insulinoma
    • (doi:10.1097/MAJ.0b013e3181ee7be2)
    • Chandra P, Yarandi SS, Khazai N, Jacobs S & Umpierrez GE. Management of intractable hypoglycemia with Yttirum-90 radioembolization in a patient with malignant insulinoma. American Journal of the Medical Sciences 2010 340 414-417. (doi:10.1097/MAJ.0b013e3181ee7be2)
    • (2010) American Journal of the Medical Sciences , vol.340 , pp. 414-417
    • Chandra, P.1    Yarandi, S.S.2    Khazai, N.3    Jacobs, S.4    Umpierrez, G.E.5
  • 28
    • 84862811548 scopus 로고    scopus 로고
    • Comparison of the NCI-CTCAE version 4.0 and version 3.0 in assessing chemoradiation-induced oral mucositis for locally advanced nasopharyngeal carcinoma
    • Liu Y-J, Zhu G-P & Guan X.Y. Comparison of the NCI-CTCAE version 4.0 and version 3.0 in assessing chemoradiation-induced oral mucositis for locally advanced nasopharyngeal carcinoma. Oral Oncology 2012 48 554-559. (http://www.ncbi.nlm.nih.gov/pubmed/22289637)
    • (2012) Oral Oncology , vol.48 , pp. 554-559
    • Liu, Y.-J.1    Zhu, G.-P.2    Guan, X.Y.3
  • 30
    • 33644874507 scopus 로고    scopus 로고
    • Prognosis of carcinoid heart disease: Analysis of 200 cases over two decades
    • (doi:10.1161/CIRCULATIONAHA.105.553750)
    • Møller JE, Pellikka PA, Bernheim AM, Schaff HV, Rubin J & Connolly HM. Prognosis of carcinoid heart disease: analysis of 200 cases over two decades. Circulation 2005 112 3320-3327. (doi:10.1161/CIRCULATIONAHA.105. 553750)
    • (2005) Circulation , vol.112 , pp. 3320-3327
    • Møller, J.E.1    Pellikka, P.A.2    Bernheim, A.M.3    Schaff, H.V.4    Rubin, J.5    Connolly, H.M.6
  • 31
    • 84857838286 scopus 로고    scopus 로고
    • ENETS consensus guidelines for the management of patients with liver and other distant metastases from neuroendocrine neoplasms of foregut, midgut, hindgut, and unknown primary
    • (doi:10.1159/000335597)
    • Pavel M, Baudin E, Couvelard A., Krenning E, Öberg K, Steinmüller T, Anlauf M, Wiedenmann B & Salazar R. ENETS Consensus Guidelines for the management of patients with liver and other distant metastases from neuroendocrine neoplasms of foregut, midgut, hindgut, and unknown primary. Neuroendo-crinology 2012 95 157-176. (doi:10.1159/000335597)
    • (2012) Neuroendo-crinology , vol.95 , pp. 157-176
    • Pavel, M.1    Baudin, E.2    Couvelard, A.3    Krenning, E.4    Öberg, K.5    Steinmüller, T.6    Anlauf, M.7    Wiedenmann, B.8    Salazar, R.9
  • 32
    • 0030695334 scopus 로고    scopus 로고
    • Diazoxide treatment for insulinoma: A national UK survey
    • (doi:10.1136/pgmj.73.864.640)
    • Gill GV, Rauf O & MacFarlane IA. Diazoxide treatment for insulinoma: a national UK survey. Postgraduate Medical Journal 1997 73 640-641. (doi:10.1136/pgmj.73.864.640)
    • (1997) Postgraduate Medical Journal , vol.73 , pp. 640-641
    • Gill, G.V.1    Rauf, O.2    MacFarlane, I.A.3
  • 34
    • 0024355315 scopus 로고
    • Aggravation of hypoglycemia in insulinoma patients by the long-acting somatostatin analogue octreotide (Sandostatin)
    • Stehouwer CD, Lems WF, Fischer H.R., Hackeng WH & Naafs MA. Aggravation of hypoglycemia in insulinoma patients by the long-acting somatostatin analogue octreotide (Sandostatin). Acta Endocrinologica 1989 121 34-40.
    • (1989) Acta Endocrinologica , vol.121 , pp. 34-40
    • Stehouwer, C.D.1    Lems, W.F.2    Fischer, H.R.3    Hackeng, W.H.4    Naafs, M.A.5
  • 35
    • 0029007787 scopus 로고
    • Octreotide exacerbated fasting hypoglycaemia in a patient with a proinsulinoma; the glucostatic importance of pancreatic glucagon
    • discussion 120-122. (doi:10.1111/j.1365-2265.1995.tb01901.x)
    • Gama R, Marks V, Wright J & Teale JD. Octreotide exacerbated fasting hypoglycaemia in a patient with a proinsulinoma; the glucostatic importance of pancreatic glucagon. Clinical Endocrinology 1995 43 117-120; discussion 120-122. (doi:10.1111/j.1365-2265.1995.tb01901.x)
    • (1995) Clinical Endocrinology , vol.43 , pp. 117-120
    • Gama, R.1    Marks, V.2    Wright, J.3    Teale, J.D.4
  • 36
    • 34447094133 scopus 로고    scopus 로고
    • Severe hypoglycaemia after long-acting octreotide in a patient with an unrecognized Malignant insulinoma
    • (doi:10.1111/j.1445-5994.2007.01371.x)
    • Healy ML, Dawson SJ, Murray RML, Zalcberg J & Jefford M. Severe hypoglycaemia after long-acting octreotide in a patient with an unrecognized malignant insulinoma. Internal Medicine Journal 2007 37 406-409. (doi:10.1111/j.1445-5994.2007.01371.x)
    • (2007) Internal Medicine Journal , vol.37 , pp. 406-409
    • Healy, M.L.1    Dawson, S.J.2    Murray, R.M.L.3    Zalcberg, J.4    Jefford, M.5
  • 37
    • 79961243200 scopus 로고    scopus 로고
    • New therapeutic options for metastatic Malignant insulinomas
    • (doi:10.1111/j.1365-2265. 2011.04145.x)
    • De Herder W.W., Van Schaik E, Kwekkeboom D & Feelders RA. New therapeutic options for metastatic malignant insulinomas. Clinical Endocrinology 2011 75 277-284. (doi:10.1111/j.1365-2265. 2011.04145.x)
    • (2011) Clinical Endocrinology , vol.75 , pp. 277-284
    • De Herder, W.W.1    Van Schaik, E.2    Kwekkeboom, D.3    Feelders, R.A.4
  • 38
    • 80051758316 scopus 로고    scopus 로고
    • Liver transplantation for the treatment of liver metastases from neuroendocrine tumors: An analysis of the UNOS database
    • (doi:10.1001/ archsurg.2011.186)
    • Gedaly R, Daily MF, Davenport D, McHugh P.P., Koch A, Angulo P & Hundley JC. Liver transplantation for the treatment of liver metastases from neuroendocrine tumors: an analysis of the UNOS database. Archive Surgery 2011 146 953-958. (doi:10.1001/ archsurg.2011.186)
    • (2011) Archive Surgery , vol.146 , pp. 953-958
    • Gedaly, R.1    Daily, M.F.2    Davenport, D.3    McHugh, P.P.4    Koch, A.5    Angulo, P.6    Hundley, J.C.7
  • 39
    • 80053339992 scopus 로고    scopus 로고
    • Effect of the tyrosine kinase inhibitors (sunitinib, sorafenib, dasatinib, and imatinib) on blood glucose levels in diabetic and nondiabetic patients in general clinical practice
    • (doi:10.1177/1078155210378913)
    • Agostino NM, Chinchilli VM, Lynch C.J., Koszyk-Szewczyk A, Gingrich R, Sivik J & Drabick JJ. Effect of the tyrosine kinase inhibitors (sunitinib, sorafenib, dasatinib, and imatinib) on blood glucose levels in diabetic and nondiabetic patients in general clinical practice. Journal of Oncology Pharmacy Practice 2011 17 197-202. (doi:10.1177/1078155210378913)
    • (2011) Journal of Oncology Pharmacy Practice , vol.17 , pp. 197-202
    • Agostino, N.M.1    Chinchilli, V.M.2    Lynch, C.J.3    Koszyk-Szewczyk, A.4    Gingrich, R.5    Sivik, J.6    Drabick, J.J.7
  • 40
    • 48149112155 scopus 로고    scopus 로고
    • Sirolimus is associated with new-onset diabetes in kidney transplant recipients
    • (doi:10.1681/ASN.2007111202)
    • Johnston O, Rose CL, Webster AC & Gill JS. Sirolimus is associated with new-onset diabetes in kidney transplant recipients. Journal of the American Society of Nephrology 2008 19 1411-1418. (doi:10.1681/ASN.2007111202)
    • (2008) Journal of the American Society of Nephrology , vol.19 , pp. 1411-1418
    • Johnston, O.1    Rose, C.L.2    Webster, A.C.3    Gill, J.S.4
  • 41
    • 33645742164 scopus 로고    scopus 로고
    • Everolimus: A review of its use in renal and cardiac transplantation
    • (doi:10.2165/ 00003495-200666040-00009)
    • Dunn C & Croom KF. Everolimus: a review of its use in renal and cardiac transplantation. Drugs 2006 66 547-570. (doi:10.2165/ 00003495-200666040-00009)
    • (2006) Drugs , vol.66 , pp. 547-570
    • Dunn, C.1    Croom, K.F.2
  • 42
    • 39449124107 scopus 로고    scopus 로고
    • Pulmonary complications of novel antineoplastic agents for solid tumors
    • (doi:10.1378/chest.07-0851)
    • Vahid B & Marik PE. Pulmonary complications of novel antineoplastic agents for solid tumors. Chest 2008 133 528-538. (doi:10.1378/chest.07-0851)
    • (2008) Chest , vol.133 , pp. 528-538
    • Vahid, B.1    Marik, P.E.2
  • 43
    • 84864954263 scopus 로고    scopus 로고
    • Incidence and management of mTOR inhibitor-associated pneumonitis in patients with metastatic renal cell carcinoma
    • (doi:10.1093/annonc/mds115)
    • Albiges L, Chamming's F, Duclos B, Stern M, Motzer RJ, Ravaud A & Camus P. Incidence and management of mTOR inhibitor-associated pneumonitis in patients with metastatic renal cell carcinoma. Annals of Oncology 2012 23 1943-1953. (doi:10.1093/annonc/mds115)
    • (2012) Annals of Oncology , vol.23 , pp. 1943-1953
    • Albiges, L.1    Chamming's, F.2    Duclos, B.3    Stern, M.4    Motzer, R.J.5    Ravaud, A.6    Camus, P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.