Genetic characterisation of Malawian pneumococci prior to the roll-out of the PCV13 vaccine using a high-throughput whole genome sequencing approach

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Everett, Dean B ^a,b   Cornick, Jennifer ^a,b   Denis, Brigitte ^a   Chewapreecha, Claire ^c   Croucher, Nicholas ^c   Harris, Simon ^c   Parkhill, Julian ^c   Gordon, Stephen ^d   Carrol, Enitan D ^b   French, Neil ^b   Heyderman, Robert S ^a,d   Bentley, Stephen D ^b,c  

^a MALAWI LIVERPOOL WELLCOME TRUST CLINICAL RESEARCH PROGRAMME   (Malawi)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^d LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PNEUMOCOCCAL CONJUGATE VACCINE 13; PNEUMOCOCCUS VACCINE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; PREVENAR13; VACCINE;

ADULT; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; CHILD; CONTROLLED STUDY; DISEASE CONTROL; GENE SWITCHING; GENETIC CONSERVATION; GENETIC HETEROGENEITY; HIGH THROUGHPUT SEQUENCING; HUMAN; MALAWIAN; MOLECULAR CLONING; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEOTIDE SEQUENCE; PNEUMOCOCCAL INFECTION; POPULATION STRUCTURE; PUBLIC HEALTH; SEROTYPE; STREPTOCOCCUS PNEUMONIAE; ADOLESCENT; ANTIBIOTIC RESISTANCE; BACTERIAL GENOME; CLASSIFICATION; DRUG EFFECT; GENETIC VARIABILITY; GENETICS; IMMUNOLOGY; INFANT; MALAWI; METHODOLOGY; MIDDLE AGED; PHYLOGENY; PRESCHOOL CHILD; SEROTYPING;

STREPTOCOCCUS PNEUMONIAE;

ADOLESCENT; ADULT; ANTI-BACTERIAL AGENTS; BASE SEQUENCE; CHILD; CHILD, PRESCHOOL; DRUG RESISTANCE, BACTERIAL; GENETIC VARIATION; GENOME, BACTERIAL; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; INFANT; MALAWI; MIDDLE AGED; PHYLOGENY; PNEUMOCOCCAL VACCINES; SEROTYPING; STREPTOCOCCUS PNEUMONIAE; VACCINES, CONJUGATE; YOUNG ADULT;

EID: 84877110544     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044250     Document Type: Article

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