Relationships between the level of alcohol consumption and abnormality in biomarkers according to facial flushing in Korean male drinkers

Korean Journal of Family Medicine

Volumn 34, Issue 2, 2013, Pages 123-130

  Kim, Seong Gu ^a   Kim, Jong Sung ^a   Kim, Sung Soo ^a   Jung, Jin Gyu ^a   Yun, Seok Jun ^a   Kim, Eo Chin ^a  

^a Chungnam National University   (South Korea)

Author keywords

Alcohol; Biological markers; Drinking; Flushing

Indexed keywords

EID: 84877103515     PISSN: 20056443     EISSN: 20926715     Source Type: Journal    
DOI: 10.4082/kjfm.2013.34.2.123     Document Type: Article

References (31)

1. Crabb DW. Ethanol oxidizing enzymes: roles in alcohol metabolism and alcoholic liver disease. Prog Liver Dis 1995;13:151-72.
2. Ehrig T, Bosron WF, Li TK. Alcohol and aldehyde dehydrogenase. Alcohol Alcohol 1990;25:105-16.
3. Yin SJ, Liao CS, Chen CM, Fan FT, Lee SC. Genetic polymorphism and activities of human lung alcohol and aldehyde dehydrogenases: implications for ethanol metabolism and cytotoxicity. Biochem Genet 1992;30:203-15.
4. Harada S, Misawa S, Agarwal DP, Goedde HW. Liver alcohol dehydrogenase and aldehyde dehydrogenase in the Japanese: isozyme variation and its possible role in alcohol intoxication. Am J Hum Genet 1980;32:8-15.
5. Crabb DW, Matsumoto M, Chang D, You M. Overview of the role of alcohol dehydrogenase and aldehyde dehydrogenase and their variants in the genesis of alcohol-related pathology. Proc Nutr Soc 2004;63:49-63.
6. Ewing JA, Rouse BA, Pellizzari ED. Alcohol sensitivity and ethnic background. Am J Psychiatry 1974;131:206-10.
7. Wilson JR, McClearn GE, Johnson RC. Ethnic variation in use and effects of alcohol. Drug Alcohol Depend 1978;3:147-51.
8. Wolff PH. Ethnic differences in alcohol sensitivity. Science 1972;175:449-50.
9. Shibuya A, Yasunami M, Yoshida A. Genotype of alcohol dehydrogenase and aldehyde dehydrogenase loci in Japanese alcohol flushers and nonflushers. Hum Genet 1989;82:14-6.
10. Litten RZ, Allen JP, Fertig JB. Gamma-glutamyltranspeptidase and carbohydrate deficient transferrin: alternative measures of excessive alcohol consumption. Alcohol Clin Exp Res 1995;19:1541-6.
11. Anton RF, Dominick C, Bigelow M, Westby C; CDTect Research Group. Comparison of Bio-Rad %CDT TIA and CDTect as laboratory markers of heavy alcohol use and their relationships with gamma-glutamyltransferase. Clin Chem 2001;47:1769-75.
12. Siemens Healthcare Diagnostics Products GmbH. N latex CDT kit. Marburg: Siemens; 2009.
13. Delanghe JR, Helander A, Wielders JP, Pekelharing JM, Roth HJ, Schellenberg F, et al. Development and multicenter evaluation of the N latex CDT direct immunonephelometric assay for serum carbohydrate-deficient transferrin. Clin Chem 2007;53:1115-21.
14. Kim SM, Kim JS, Kim KM, Pack HJ, Lee DH, Kim SS, et al. Carbohydrate-deficient transferrin as a marker of heavy drinking in Korean males. J Korean Med Sci 2007;22:652-5.
15. National Institute on Alcohol Abuse and Alcoholism. Helping patients who drink too much: a clinician's guide: updated 2005 edition [Internet]. Bethesda: National Institutes of Health Publication; 2007. Appendix, what's a standard drink? [cited 2012 Aug 12]. Available from: http://pubs.niaaa.nih.gov/publications/Practitioner/CliniciansGuide2005/guide.pdf.
16. Higuchi S, Muramatsu T, Shigemori K, Saito M, Kono H, Dufour MC, et al. The relationship between low Km aldehyde dehydrogenase phenotype and drinking behavior in Japanese. J Stud Alcohol 1992;53:170-5.
17. National Institutes of Health. Third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III): final report [Internet]. Bethesda: National Institutes of Health; 2002 [cited 2012 Dec 4]. Available from: http://www.nhlbi.nih.gov/guidelines/cholesterol/atp3full.pdf.
18. Peterson K. Biomarkers for alcohol use and abuse: a summary. Alcohol Res Health 2004-2005;28:30-7.
19. American Psychiatric Association. Diagnostic and statistical manual of mental disorders: DSM-IV. 4th ed. Washington (DC): American Psychiatric Association; 2000.
20. Ministry of Health and Welfare; Korea Centers for Disease Control and Prevention. Korea Health Statistics 2010: Korea National Health and Nutrition Examination Survey (KNHANES V-1) [Internet]. Seoul: Ministry of Health and Welfare; 2011 [cited 2012 Aug 12]. Available from: http://www.bokjiro.go.kr/data/statusView.do?board_sid=297&data_sid=5771475.
21. McDowell MA, Fryar CD, Ogden CL, Flegal KM. Anthropometric reference data for children and adults: United States, 2003-2006. National Health Statistics Reports, number 10 [Internet]. Atlanta: Centers for Disease Control and Prevention; 2008 [cited 2012 Aug 12]. Available from: http://www.cdc.gov/nchs/data/nhsr/nhsr010.pdf.
22. Anton RF. Carbohydrate-deficient transferrin for detection and monitoring of sustained heavy drinking. What have we learned? Where do we go from here?. Alcohol 2001;25:185-8.
23. Xin Y, Lasker JM, Lieber CS. Serum carbohydrate-deficient transferrin: mechanism of increase after chronic alcohol intake. Hepatology 1995;22:1462-8.
24. Enomoto N, Takase S, Takada N, Takada A. Alcoholic liver disease in heterozygotes of mutant and normal aldehyde dehydrogenase-2 genes. Hepatology 1991;13:1071-5.
25. Zierau F, Hardt F, Henriksen JH, Holm SS, Jorring S, Melsen T, et al. Validation of a self-administered modified CAGE test (CAGE-C) in a somatic hospital ward: comparison with biochemical markers. Scand J Clin Lab Invest 2005;65:615-22.
26. Yersin B, Nicolet JF, Dercrey H, Burnier M, van Melle G, Pecoud A. Screening for excessive alcohol drinking: comparative value of carbohydrate-deficient transferrin, gammaglutamyltransferase, and mean corpuscular volume. Arch Intern Med 1995;155:1907-11.
27. Allen JP, Sillanaukee P, Strid N, Litten RZ. Assessing alcohol problems: a guide for clinicians and researchers [Internet]. 2nd ed. Bethesda: National Institute on Alcohol Abuse and Alcoholism; 2007. Screening: biomarkers of heavy drinking [cited 2012 Aug 12]. Available from: http://pubs.niaaa.nih.gov/publications/AssessingAlcohol/allen.pdf.
28. Jung JG, Kim JS, Oh MK. The role of the flushing response in the relationship between alcohol consumption and insulin resistance. Alcohol Clin Exp Res 2010;34:1699-704.
29. Jung JG, Kim JS, Yoon SJ, Oh MK. Relationships among alcohol consumption, facial flushing response, and metabolic syndrome in healthy men. Ann Epidemiol 2012;22:480-6.
30. Ishiguro S, Sasazuki S, Inoue M, Kurahashi N, Iwasaki M, Tsugane S, et al. Effect of alcohol consumption, cigarette smoking and flushing response on esophageal cancer risk: a population-based cohort study (JPHC study). Cancer Lett 2009;275:240-6.
31. Yokoyama T, Yokoyama A, Kato H, Tsujinaka T, Muto M, Omori T, et al. Alcohol flushing, alcohol and aldehyde dehydrogenase genotypes, and risk for esophageal squamous cell carcinoma in Japanese men. Cancer Epidemiol Biomarkers Prev 2003;12(11 Pt 1):1227-33.