The role of the flushing response in the relationship between alcohol consumption and insulin resistance

Alcoholism: Clinical and Experimental Research

Volumn 34, Issue 10, 2010, Pages 1699-1704

  Jung, Jin Gyu ^a   Kim, Jong Sung ^a   Oh, Mi Kyeong ^b  

^a Chungnam National University   (South Korea)

^b University of Ulsan   (South Korea)

Author keywords

Alcohol Flushing Response; Drinking; Insulin Resistance

Indexed keywords

ALCOHOL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ALCOHOL CONSUMPTION; ARTICLE; BLOOD PRESSURE; BODY MASS; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIABETES MELLITUS; EXERCISE; FLUSHING; HOMEOSTASIS; HUMAN; HUMAN EXPERIMENT; INSULIN RESISTANCE; KOREA; LIPOPROTEIN BLOOD LEVEL; LOGISTIC REGRESSION ANALYSIS; MALE; MEDICAL RECORD; PRIORITY JOURNAL; SMOKING; TRIACYLGLYCEROL BLOOD LEVEL; WAIST CIRCUMFERENCE;

ALCOHOL DRINKING; ALDEHYDE DEHYDROGENASE; ASIAN CONTINENTAL ANCESTRY GROUP; CROSS-SECTIONAL STUDIES; FLUSHING; HUMANS; INSULIN RESISTANCE; MALE; MIDDLE AGED; RISK FACTORS;

EID: 77957365343     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2010.01256.x     Document Type: Article

References (32)

1. Agarwal DP, Harada S, Goedde HW (1981) Racial differences in biological sensitivity to ethanol: the role of alcohol dehydrogenase and aldehyde dehydrogenase isozymes. Alcohol Clin Exp Res 5 : 12 16. (Pubitemid 12242369)
2. Ajani UA, Hennekens CH, Spelsberg A, Manson JE (2000) Alcohol consumption and risk of type 2 diabetes mellitus among US male physicians. Arch Intern Med 160 : 1025 1030. (Pubitemid 30191933)
3. Bell RA, D'Agostino RB, Mayer EJ, Haffner SM, Martin MA (2000) Associations between alcohol consumption and insulin sensitivity and cardiovascular disease risk factors. Diabetes Care 23 : 1630 1636.
4. Bell LM, Watts K, Siafarikas A, Thompson A, Ratnam N, Bulsara M, Finn J, O'Driscoll G, Green DJ, Jones TW, Davis EA (2007) Exercise alone reduces insulin resistance in obese children independently of changes in body composition. J Clin Endocrinol Metab 92 : 4230 4235. (Pubitemid 350074736)
5. Enomoto N, Takase S, Takada N, Takada A (1991) Alcoholic liver disease in heterozygotes of mutant and normal aldehyde dehydrogenase2 genes. Hepatology 13 : 1071 1075.
6. Eriksson CJ (2001) The role of acetaldehyde in the actions of alcohol (update 2000). Alcohol Clin Exp Res 25 : 15S 32S. (Pubitemid 32545008)
7. Feskens EJ, Kromhout D (1989) Cardiovascular risk factors and the 25-year incidence of diabetes mellitus in middle-aged men. The Zutphen Study. Am J Epidemiol 130 : 1101 1108. (Pubitemid 20016347)
8. Geloneze B, Tambascia MA (2006) Laboratorial evaluation and diagnosis of insulin resistance. Arq Bras Endocrinol Metabol 50 : 208 215. (Pubitemid 43799107)
9. Goldberg RB, Jacobson TA (2008) Effects of niacin on glucose control in patients with dyslipidemia. Mayo Clin Proc 83 (4 470 478. (Pubitemid 351536472)
10. Holbrook TL, Barrett-Connor E, Wingard DL (1990) A prospective population-based study of alcohol use and non-insulin-dependent diabetes mellitus. Am J Epidemiol 132 : 902 909. (Pubitemid 20363669)
11. Ishiguro S, Sasazuki S, Inoue M, Kurahashi N, Iwasaki M, Tsugane S JPHC Study Group (2009) Effect of alcohol consumption, cigarette smoking and flushing response on esophageal cancer risk: a population-based cohort study (JPHC study). Cancer Lett 275 : 240 246.
12. Kamanna VS, Kashyap ML (2008) Mechanism of action of niacin. Am J Cardiol 101 (8A 20B 26B.
13. Kao WH, Puddey IB, Boland LL, Watson RL, Brancati FL (2001) Alcohol consumption and the risk of type 2 diabetes mellitus: atherosclerosis risk in communities study. Am J Epidemiol 154 : 748 757. (Pubitemid 32971496)
14. Kim SG, Lim HS, Cheong HK, Kim CS, Seo HJ (2007) Incidence and risk factors of insulin resistance syndrome in 20-59 year-old Korean male workers. J Korean Med Sci 22 : 968 972.
15. Lazarus R, Sparrow D, Weiss ST (1997) Alcohol intake and insulin levels. The normative aging study. Am J Epidemiol 145 : 909 916. (Pubitemid 27200777)
16. Lee S, Choi S, Kim HJ, Chung YS, Lee KW, Lee HC, Huh KB, Kim DJ (2006) Cutoff values of surrogate measures of insulin resistance for metabolic syndrome in Korean non-diabetic adults. J Korean Med Sci 21 : 695 700. (Pubitemid 44199326)
17. Maiese K, Morhan SD, Chong ZZ (2007) Oxidative stress biology and cell injury during type 1 and type 2 diabetes mellitus. Curr Neurovasc Res 4 (1 63 71. (Pubitemid 46280293)
18. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC (1985) Homeostasis model assessment: insulin resistance and -cell function from fasting plasma glucose and insulin concentration in man. Diabetologia 28 : 412 419. (Pubitemid 15018832)
19. Meigs JB, Larson MG, Fox CS, Keaney JF Jr., Vasan RS, Benjamin EJ (2007) Association of oxidative stress, insulin resistance, and diabetes risk phenotypes: the Framingham offspring study. Diabetes Care 30 (10 2529 2535.
20. Mizoi Y, Tatsuno Y, Adachi J, Kogame M, Fukunaga T, Fujiwara S, Hishida S, Ijiri I (1983) Alcohol sensitivity related to polymorphism of alcohol-metabolizing enzymes in Japanese. Pharmacol Biochem Behav 18 : 127 133. (Pubitemid 14119317)
21. Nordback IH, MacGowan S, Potter JJ, Cameron JL (1991) The role of acetaldehyde in the pathogenesis of acute alcoholic pancreatitis. Ann Surg 214 : 671 678.
22. Ogden CL, Fryar CD, Carroll MD, Flegal KM (2004) Mean body weight, height, and body mass index, United States 1960-2002. Adv Data 347 : 1 17.
23. Park K, Gross M, Lee DH, Holvoet P, Himes JH, Shikany JM, Jacobs DR Jr. (2009) Oxidative stress and insulin resistance: the coronary artery risk development in young adults study. Diabetes Care 32 (7 1302 1307.
24. Rao G (2001) Insulin resistance syndrome. Am Fam Physician 15 (63 1159 1163. (Pubitemid 32238877)
25. Razay G, Heaton KW (1997) Moderate alcohol consumption has been shown previously to improve insulin sensitivity in men. BMJ 314 : 443 444. (Pubitemid 27067817)
26. Rockville MD. A pocket guide for alcohol screening and brief intervention [NIAAA website]. 2005. Available at: http://www.niaaa.nih.gov. Accessed April 1, 2008.
27. Thomasson HR, Edenberg HJ, Crabb DW, Mai XL, Jerome RE, Li TK, Wang SP, Lin YT, Lu RB, Yin SJ (1991) Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men. Am J Hum Genet 48 : 677 681.
28. Tsumura K, Hayashi T, Suematsu C, Endo G, Fujii S, Okada K (1999) Daily alcohol consumption and the risk of type 2 diabetes in Japanese men. Diabetes Care 22 : 1432 1437.
29. Wei M, Gibbons LW, Mitchell TL, Kampert JB, Blair SN (2000) Alcohol intake and incidence of type 2 diabetes in men. Diabetes Care 23 : 18 22. (Pubitemid 30022888)
30. Yokoyama A, Muramatsu T, Ohmori T, Kumagai Y, Hiquchi S, Ishii H (1997) Reliability of a flushing questionnaire and the ethanol patch test in screening for inactive aldehyde dehydrogenase-2 and alcohol-related cancer risk. Cancer Epidemiol Biomark Prev 6 : 1105 1107. (Pubitemid 28007425)
31. Yokoyama T, Yokoyama A, Kato H, Tsujinaka T, Muto M, Omori T, Haneda T, Kumagai Y, Igaki H, Yokoyama M, Watanabe H (2003) Alcohol flushing, alcohol and aldehyde dehydrogenase genotypes, and risk for esophageal squamous cell carcinoma in Japanese men. Cancer Epidemiol Biomarkers Prev 12 : 1227 1233. (Pubitemid 37499449)
32. Yoshida A, Huang IY, Ikawa M (1984) Molecular abnormality of an inactive aldehyde dehydrogenase variant commonly found in Orientals. Proc Natl Acad Sci USA 81 : 258 261. (Pubitemid 14180868)