Simvastatin suppresses RANTES-mediated neutrophilia in polyinosinic- polycytidylic acid-induced pneumonia

European Respiratory Journal

Volumn 41, Issue 5, 2013, Pages 1147-1156

  Lee, Chang Seok ^a   Yi, Eun Hee ^a   Lee, Jin Ku ^a   Won, Cheolhee ^a   Lee, Young Ju ^a   Shin, Min Kyung ^a   Yang, Young Mok ^b   Chung, Myung Hee ^a   Lee, Jung Weon ^c   Sung, Sang Hyun ^c   Ye, Sang Kyu ^a  

^a Seoul National University College of Medicine   (South Korea)

^b Konkuk University School of Medicine   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Double stranded RNA; Inflammation; RANTES; Signal transducer and activator of transcription 3; Statin

Indexed keywords

DOUBLE STRANDED RNA; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN KINASE B; RANTES; SHORT HAIRPIN RNA; SIMVASTATIN; STAT3 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME INACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY CELL; LUNG ALVEOLUS EPITHELIUM; MOUSE; NEUTROPHIL CHEMOTAXIS; NEUTROPHILIA; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

DOUBLE-STRANDED RNA; INFLAMMATION; RANTES; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3; STATIN;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BRONCHI; CELL LINE, TUMOR; CHEMOKINE CCL5; DISEASE MODELS, ANIMAL; DOXYCYCLINE; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; FEMALE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INFLAMMATION; LUNG; MICE; MICE, INBRED BALB C; NEUTROPHILS; PNEUMONIA; POLY I-C; RNA, SMALL INTERFERING; SIMVASTATIN; STAT3 TRANSCRIPTION FACTOR;

EID: 84877095321     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00050612     Document Type: Article

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