Magnetic resonance and computed tomography imaging of the structural and functional changes of pulmonary arterial hypertension

Journal of Thoracic Imaging

Volumn 28, Issue 3, 2013, Pages 178-195

  Schiebler, Mark L ^a   Bhalla, Sanjeev ^b   Runo, James ^a   Jarjour, Nizar ^a   Roldan, Alejandro ^a   Chesler, Naomi ^a   François, Christopher J ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Heart catheterization; Hypertension; Magnetic resonance angiography; Multidetector computed tomography; Pulmonary; Thromboembolism

Indexed keywords

TECHNETIUM 99M;

ARTERY COMPLIANCE; ARTERY DIAMETER; CARDIAC IMAGING; CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION; CLINICAL FEATURE; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; CONFERENCE PAPER; COR PULMONALE; FRACTAL ANALYSIS; GOLD STANDARD; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE FUNCTION; HEART RIGHT VENTRICLE EJECTION FRACTION; HEART RIGHT VENTRICLE ENDDIASTOLIC VOLUME; HEART RIGHT VENTRICLE FUNCTION; HEART STROKE VOLUME; HEART VALVE REGURGITATION; HEPATOPULMONARY SYNDROME; INCIDENCE; INFERIOR CAVA VEIN; LUNG ARTERY PRESSURE; LUNG EMBOLISM; LUNG PERFUSION; LUNG VENTILATION; MAGNETIC RESONANCE ANGIOGRAPHY; MEASUREMENT; NON INVASIVE PROCEDURE; NUCLEAR MAGNETIC RESONANCE IMAGING; PREVALENCE; PULMONARY ARTERY; PULMONARY HYPERTENSION; PULMONARY SHUNT; SURVIVAL; TRANSTHORACIC ECHOCARDIOGRAPHY; TRUNK;

HUMANS; HYPERTENSION, PULMONARY; MAGNETIC RESONANCE IMAGING; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84877081832     PISSN: 08835993     EISSN: 15360237     Source Type: Journal    
DOI: 10.1097/RTI.0b013e31828d5c48     Document Type: Conference Paper

References (80)

1. Humbert M. The burden of pulmonary hypertension. Eur Respir J. 2007;30:1-2
2. Strange G, Playford D, Stewart S, et al. Pulmonary hypertension: Prevalence and mortality in the Armadale echocardiography cohort. Heart. 2012;98:1805-1811
3. Simonneau G, Robbins IM, Beghetti M, et al. Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol. 2009;54(suppl):S43-S54
4. Galie N, Hoeper MM, Humbert M, et al. Guidelines for the diagnosis and treatment of pulmonary hypertension: The Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). Eur Heart J. 2009;30:2493-2537
5. Chin KM, Kim NH, Rubin LJ. The right ventricle in pulmonary hypertension. Coron Artery Dis. 2005;16:13-18
6. Humbert M, Sitbon O, Chaouat A, et al. Pulmonary arterial hypertension in France: Results from a national registry. Am J Respir Crit Care Med. 2006;173:1023-1030
7. Rich S, Dantzker DR, Ayres SM, et al. Primary pulmonary hypertension. A national prospective study. Ann Intern Med. 1987;107:216-223
8. Badesch DB, Raskob GE, Elliott CG, et al. Pulmonary arterial hypertension: Baseline characteristics from the REVEAL Registry. Chest. 2010;137:376-387
9. Thenappan T, Shah SJ, Rich S, et al. USA-based registry for pulmonary arterial hypertension: 1982-2006. Eur Respir J. 2007;30:1103-1110
10. Peacock AJ, Murphy NF, McMurray JJ, et al. An epidemiological study of pulmonary arterial hypertension. Eur Respir J. 2007;30:104-109
11. Hyduk A, Croft JB, Ayala C, et al. Pulmonary hypertension surveillance -United States, 1980-2002. MMWR Surveill Summ. 2005;54:1-28
12. D'Alonzo GE, Barst RJ, Ayres SM, et al. Survival in patients with primary pulmonary hypertension. Results from a national prospective registry. Ann Intern Med. 1991;115:343-349
13. Hui-li G. The management of acute pulmonary arterial hypertension. Cardiovasc Ther. 2011;29:153-175
14. van Beek EJ, Kuijer PM, Buller HR, et al. The clinical course of patients with suspected pulmonary embolism. Arch Intern Med. 1997;157:2593-2598
15. Goodman LR, Lipchik RJ, Kuzo RS, et al. Subsequent pulmonary embolism: Risk after a negative helical CT pulmonary angiogram -prospective comparison with scintigraphy. Radiology. 2000;215:535-542
16. Qanadli SD, El Hajjam M, Vieillard-Baron A, et al. New CT index to quantify arterial obstruction in pulmonary embolism: Comparison with angiographic index and echocardiography. Am J Roentgenol. 2001;176:1415-1420
17. Kuriyama K, Gamsu G, Stern RG, et al. CT-determined pulmonary artery diameters in predicting pulmonary hypertension. Invest Radiol. 1984;19:16-22
18. Frank H, Globits S, Glogar D, et al. Detection and quantification of pulmonary artery hypertension with MR imaging: Results in 23 patients. Am J Roentgenol. 1993;161:27-31
19. Murray TI, Boxt LM, Katz J, et al. Estimation of pulmonary artery pressure in patients with primary pulmonary hypertension by quantitative analysis of magnetic resonance images. J Thorac Imaging. 1994;9:198-204
20. Edwards PD, Bull RK, Coulden R. CT measurement of main pulmonary artery diameter. Br J Radiol. 1998;71: 1018-1020
21. Sanal S, Aronow WS, Ravipati G, et al. Prediction of moderate or severe pulmonary hypertension by main pulmonary artery diameter and main pulmonary artery diameter/ascending aorta diameter in pulmonary embolism. Cardiol Rev. 2006;14: 213-214
22. Beiderlinden M, Kuehl H, Boes T, et al. Prevalence of pulmonary hypertension associated with severe acute respiratory distress syndrome: Predictive value of computed tomography. Intensive Care Med. 2006;32:852-857
23. Zisman DA, Karlamangla AS, Ross DJ, et al. High-resolution chest CT findings do not predict the presence of pulmonary hypertension in advanced idiopathic pulmonary fibrosis. Chest. 2007;132:773-779
24. Ghanem MK, Makhlouf HA, Agmy GR, et al. Evaluation of recently validated non-invasive formula using basic lung functions as new screening tool for pulmonary hypertension in idiopathic pulmonary fibrosis patients. Ann Thorac Med. 2009; 4:187-196
25. Linguraru MG, Pura JA, Van Uitert RL, et al. Segmentation and quantification of pulmonary artery for noninvasive CT assessment of sickle cell secondary pulmonary hypertension. Med Phys. 2010;37:1522-1532
26. Tan RT, Kuzo R, Goodman LR, et al. Utility of CT scan evaluation for predicting pulmonary hypertension in patients with parenchymal lung disease. Medical College of Wisconsin Lung Transplant Group. Chest. 1998;113:1250-1256
27. Heyer CM, Lemburg SP, Knoop H, et al. Multidetector-CT angiography in pulmonary embolism-can image parameters predict clinical outcome? Eur Radiol. 2011;21:1928-1937
28. van de Veerdonk MC, Kind T, Marcus JT, et al. Progressive right ventricular dysfunction in patients with pulmonary arterial hypertension responding to therapy. J Am Coll Cardiol. 2011;58:2511-2519
29. van Wolferen SA, Marcus JT, Boonstra A, et al. Prognostic value of right ventricular mass, volume, and function in idiopathic pulmonary arterial hypertension. Eur Heart J. 2007;28:1250-1257
30. Mathai SC, Sibley CT, Forfia PR, et al. Tricuspid annular plane systolic excursion is a robust outcome measure in systemic sclerosis-Associated pulmonary arterial hypertension. J Rheumatol. 2011;38:2410-2418
31. Gan CT, Lankhaar JW, Westerhof N, et al. Noninvasively assessed pulmonary artery stiffness predicts mortality in pulmonary arterial hypertension. Chest. 2007;132:1906-1912
32. Ng CS, Wells AU, Padley SPA. CT sign of chronic pulmonary arterial hypertension: The ratio of main pulmonary artery to aortic diameter. J Thorac Imaging. 1999;14:270-278
33. Stein PD, Chenevert TL, Fowler SE, et al. Gadoliniumenhanced magnetic resonance angiography for pulmonary embolism: A multicenter prospective study (PIOPED III). Ann Intern Med. 2010;152:434-443, W142-W433
34. Revel MP, Sanchez O, Couchon S, et al. Diagnostic accuracy of magnetic resonance imaging for an acute pulmonary embolism: Results of the 'IRM-EP' study. J Thromb Haemost. 2012;10:743-750
35. Kalb B, Sharma P, Tigges S, et al. MR imaging of pulmonary embolism: Diagnostic accuracy of contrast-enhanced 3D MR pulmonary angiography, contrast-enhanced low-flip angle 3D GRE, and nonenhanced free-induction FISP sequences. Radiology. 2012;263:271-278
36. Schiebler ML, Nagle SK, Francois CJ, et al. Effectiveness of MR angiography for the primary diagnosis of acute pulmonary embolism: Clinical outcomes at 3 months and 1 year. J Magn Reson Imaging. 2013. (In press) (DOI 10.1002/jmri.24057
37. Carrier M, Righini M, Wells PS, et al. Subsegmental pulmonary embolism diagnosed by computed tomography: Incidence and clinical implications. A systematic review and meta-Analysis of the management outcome studies. J Thromb Haemost. 2010;8:1716-1722
38. Pijpe A, Andrieu N, Easton DF, et al. Exposure to diagnostic radiation and risk of breast cancer among carriers of BRCA1/2 mutations: Retrospective cohort study (GENE-RAD-RISK). BMJ. 2012;345:e5660
39. Saggar R, Sitbon O. Hemodynamics in pulmonary arterial hypertension: Current and future perspectives. Am J Cardiol. 2012;110(suppl):S9-S15
40. Sosland RP, Gupta K. Images in cardiovascular medicine: McConnell's sign. Circulation. 2008;118:e517-e518
41. Benza RL, Miller DP, Gomberg-Maitland M, et al. Predicting survival in pulmonary arterial hypertension: Insights from the Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL). Circulation. 2010;122:164-172
42. Cho EJ, Jiamsripong P, Calleja AM, et al. Right ventricular free wall circumferential strain reflects graded elevation in acute right ventricular afterload. Am J Physiol Heart Circ Physiol. 2009;296:H413-H420
43. Devaraj A, Wells AU, Meister MG, et al. Pulmonary hypertension in patients with bronchiectasis: Prognostic significance of CT signs. Am J Roentgenol. 2011;196:1300-1304
44. Frazier AA, Franks TJ, Mohammed TL, et al. From the archives of the AFIP: Pulmonary veno-occlusive disease and pulmonary capillary hemangiomatosis. Radiographics. 2007; 27:867-882
45. McAdams HP, Erasmus J, Crockett R, et al. The hepatopulmonary syndrome: Radiologic findings in 10 patients. Am J Roentgenol. 1996;166:1379-1385
46. Porres-Aguilar M, Altamirano JT, Torre-Delgadillo A, et al. Portopulmonary hypertension and hepatopulmonary syndrome: A clinician-oriented overview. Eur Respir Rev. 2012;21:223-233
47. Dartevelle P, Fadel E, Mussot S, et al. Chronic thromboembolic pulmonary hypertension. Eur Respir J. 2004;23:637-648
48. Willemink MJ, van Es HW, Koobs L, et al. CT evaluation of chronic thromboembolic pulmonary hypertension. Clin Radiol. 2012;67:277-285
49. Rossi A, Attina D, Borgonovi A, et al. Evaluation of mosaic pattern areas in HRCT with Min-IP reconstructions in patients with pulmonary hypertension: Could this evaluation replace lung perfusion scintigraphy? Eur J Radiol. 2012;81:e1-e6
50. Haitao S, Ning L, Lijun G, et al. Fractal dimension analysis of MDCT images for quantifying the morphological changes of the pulmonary artery tree in patients with pulmonary hypertension. Korean J Radiol. 2011;12:289-296
51. Wells JM, Washko GR, Han MK, et al. Pulmonary arterial enlargement and acute exacerbations of COPD. N Engl J Med. 2012;367:913-921
52. Lin FY, Devereux RB, Roman MJ, et al. The right sided great vessels by cardiac multidetector computed tomography: Normative reference values among healthy adults free of cardiopulmonary disease, hypertension, and obesity. Acad Radiol. 2009;16:981-987
53. Devaraj A, Wells AU, Meister MG, et al. Detection of pulmonary hypertension with multidetector CT and echocardiography alone and in combination. Radiology. 2010;254: 609-616
54. Johnson KM, Fain SB, Schiebler ML, et al. Optimized 3D ultrashort echo time pulmonary MRI. Magn Reson Med. 2012. doi: 10.1002/mrm.24570
55. Liu M, Ma ZH, Guo XJ, et al. A septal angle measured on computed tomographic pulmonary angiography can noninvasively estimate pulmonary vascular resistance in patients with chronic thromboembolic pulmonary hypertension. J Thorac Imaging. 2012;27:325-330
56. Bradlow WM, Gibbs JS, Mohiaddin RH. Cardiovascular magnetic resonance in pulmonary hypertension. J Cardiovasc Magn Res. 2012;14:1-12
57. Ley S, Mereles D, Risse F, et al. Quantitative 3D pulmonary MR-perfusion in patients with pulmonary arterial hypertension: Correlation with invasive pressure measurements. Eur J Radiol. 2007;61:251-255
58. Oberholzer K, Romaneehsen B, Kunz P, et al. Contrastenhanced 3D MR angiography of the pulmonary arteries with integrated parallel acquisition technique (iPAT) in patients with chronic-Thromboembolic pulmonary hypertension CTEPH -sagittal or coronal acquisition? RoFo Fortschr Geb Rontgenstra Nuklearmedizin. 2004;176:605-609
59. Ghio S, Gavazzi A, Campana C, et al. Independent and additive prognostic value of right ventricular systolic function and pulmonary artery pressure in patients with chronic heart failure. J Am Coll Cardiol. 2001;37:183-188
60. Sanz J, Dellegrottaglie S, Kariisa M, et al. Prevalence and correlates of septal delayed contrast enhancement in patients with pulmonary hypertension. Am J Cardiol. 2007;100: 731-735
61. Rajaram S, Swift AJ, Capener D, et al. Diagnostic accuracy of contrast-enhanced MR angiography and unenhanced proton MR imaging compared with CT pulmonary angiography in chronic thromboembolic pulmonary hypertension. Eur Radiol. 2012;22:310-317
62. Marcus JT, Gan CT, Zwanenburg JJ, et al. Interventricular mechanical asynchrony in pulmonary arterial hypertension: Left-To-right delay in peak shortening is related to right ventricular overload and left ventricular underfilling. J Am Coll Cardiol. 2008;51:750-757
63. Frank O. The basic shape of the arterial pulse. First treatise: Mathematical analysis. 1899. J Mol Cell Cardiol. 1990;22: 255-277
64. Debl K, Djavidani B, Buchner S, et al. Quantification of leftto-right shunting in adult congenital heart disease: Phasecontrast cine MRI compared with invasive oximetry. Br J Radiol. 2009;82:386-391
65. Sommer G, Bremerich J, Lund G. Magnetic resonance imaging in valvular heart disease: Clinical application and current role for patient management. J Magn Res Imaging. 2012;35: 1241-1252
66. Lederlin M, Bauman G, Eichinger M, et al. Functional MRI using Fourier decomposition of lung signal: Reproducibility of ventilation-And perfusion-weighted imaging in healthy volunteers. Eur J Radiol. 2013; PMID:23295084
67. Bauman G, Scholz A, Rivoire J, et al. Lung ventilation-And perfusion-weighted Fourier decomposition magnetic resonance imaging: In vivo validation with hyperpolarized (3) He and dynamic contrast-enhanced MRI. Magn Res Med. 2013; 69:229-237
68. Kilner PJ, Yang GZ, Mohiaddin RH, et al. Helical and retrograde secondary flow patterns in the aortic arch studied by three-directional magnetic resonance velocity mapping. Circulation. 1993;88(pt 1):2235-2247
69. Kilner PJ, Yang GZ, Wilkes AJ, et al. Asymmetric redirection of flow through the heart. Nature. 2000;404:759-761
70. Markl M, Kilner PJ, Ebbers T. Comprehensive 4D velocity mapping of the heart and great vessels by cardiovascular magnetic resonance. J Cardiovasc Magn Res. 2011;13:1-22
71. Reiter G, Reiter U, Kovacs G, et al. Magnetic resonancederived 3-dimensional blood flow patterns in the main pulmonary artery as a marker of pulmonary hypertension and a measure of elevated mean pulmonary arterial pressure. Circ Cardiovasc Imaging. 2008;1:23-30
72. Ohno Y, Hatabu H, Murase K, et al. Primary pulmonary hypertension: 3D dynamic perfusion MRI for quantitative analysis of regional pulmonary perfusion. Am J Roentgenol. 2007;188:48-56
73. Meier P, Zierler KL. On the theory of the indicator-dilution method for measurement of blood flow and volume. J Appl Physiol. 1954;6:731-744
74. Ohno Y, Murase K, Higashino T, et al. Assessment of bolus injection protocol with appropriate concentration for quantitative assessment of pulmonary perfusion by dynamic contrast-enhanced MR imaging. J Magn Res Imaging. 2007; 25:55-65
75. Risse F, Semmler W, Kauczor HU, et al. Dual-bolus approach to quantitative measurement of pulmonary perfusion by contrast-enhanced MRI. J Magn Res Imaging. 2006;24: 1284-1290
76. Oldendorf WH, Kitano M, Shimizu S, et al. Hematocrit of the human cranial blood pool. Circ Res. 1965;17:532-539
77. Westerhof N, Lankhaar JW, Westerhof BE. The arterial Windkessel. Med Biol Eng Comput. 2009;47:131-141
78. Westerhof N, Elzinga G, Sipkema P. An artificial arterial system for pumping hearts. J Appl Physiol. 1971;31: 776-781
79. Bellofiore A, Roldan-Alzate A, Besse M, et al. Impact of acute pulmonary embolization on arterial stiffening and right ventricular function in dogs. Ann Biomed Eng. 2012;41:195-204
80. Stevens GR, Garcia-Alvarez A, Sahni S, et al. RV dysfunction in pulmonary hypertension is independently related to pulmonary artery stiffness. JACC Cardiovasc Imaging. 2012;5: 378-387