Effects of naringin on proliferation, differentiation and maturation of rat calvarial osteoblasts in vitro

Zhongguo Zhongyao Zazhi

Volumn 38, Issue 1, 2013, Pages 105-111

  Zhai, Yuan Kun ^a   Niu, Yin Bo ^a   Pan, Ya Lei ^a   Li, Chen Rui ^a   Wu, Xiang Long ^a   Mei, Qi Bing ^a,b  

^a NORTHWESTERN POLYTECHNICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Differentiation; Naringin; Phytoestrogen; Proliferation; ROB

Indexed keywords

ALKALINE PHOSPHATASE; AURANTIIN; BASIC FIBROBLAST GROWTH FACTOR RECEPTOR; BONE MORPHOGENETIC PROTEIN 2; COLLAGEN TYPE 1; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; MESSENGER RNA; OSTEOCALCIN; OSTEOPONTIN; PHYTOESTROGEN; RNA; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CULTURE MEDIUM; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVITY; IN VITRO STUDY; NONHUMAN; OSTEOBLAST; OSTEOPOROSIS; PROTEIN EXPRESSION; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SKULL; WESTERN BLOTTING;

ALKALINE PHOSPHATASE; ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; DRUGS, CHINESE HERBAL; FLAVANONES; INSULIN-LIKE GROWTH FACTOR I; OSTEOBLASTS; OSTEOCALCIN; RATS; RATS, SPRAGUE-DAWLEY; SKULL;

EID: 84877076797     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: 10.4268/cjcmm20130121     Document Type: Article

References (18)

1. 2009, 22(1):66.
2. 2009, 13(37): 7254.
3. Hsu C K, Liao M H, Tai Y T, et al. Nanoparticles prepared from the water extract of Gusuibu (Drynaria fortunei J. Sm.) protects osteoblasts against insults and promotes cell maturation [J]. Int J Nanomedicine, 2011, 6: 1405.
4. Shi X L, Liu K, Wu L G. Interventional value of total flavonoids from Rhizoma Drynariae on Cathepsin K, a potential target of osteoporosis [J]. Chin J Integr Med, 2011, 17(7): 556.
5. Pari L, Amudha K. Hepatoprotective role of naringin on nickel-induced toxicity in male Wistar rats[J]. Eur J Pharmacol, 2011, 650(1): 364.
6. Liu Y, Wu H, Nie Y, et al. Naringin attenuates acute lung injury in LPS-treated mice by inhibiting NF-kappaB pathway [J]. Int Immunopharmacol, 2011, 11(10): 1606.
7. Liu M, Yang C, Zou W, et al. Toxicokinetics of naringin, a putative antitussive, after 184-day repeated oral administration in rats[J]. Environ Toxicol Pharmacol, 2011, 31(3): 485.
8. 2005, 7(4):5.
9. Pang W Y, Wang X L, Mok S K, et al. Naringin improves bone properties in ovariectomized mice and exerts oestrogen-like activities in rat osteoblast-like (UMR-106) cells[J]. Br J Pharmacol, 2010, 159(8): 1693.
10. The writing group for the women's health initiative investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal woman: principle results from the woman's health initiative randomized controlled trial [J]. JAMA, 2002, 288:321.
11. Hedelin M, Lof M, Andersson T M, et al. Dietary phytoestrogens and the risk of ovarian cancer in the women's lifestyle and health cohort study [J]. Cancer Epidemiol Biomarkers Prev, 2011, 20(2): 308.
12. Wang L, Huang Y, Pan K, et al. Osteogenic responses to different concentrations/ratios of BMP-2 and bFGF in bone formation[J]. Ann Biomed Eng, 2010, 38(1): 77.
13. Kanbur N O, Derman O, Kinik E. The relationships between pubertal development, IGF-1 axis, and bone formation in healthy adolescents[J]. J Bone Miner Metab, 2005, 23 (1): 76.
14. Nakashima K, Zhou X, Kunkel G, et al. The novel zinc finger containing transcription factor osterix is required for osteoblast differentiation and bone formation[J]. Cell, 2002, 108(1):17.
15. Boonchird C, Mahapanichkul T, Cherdshewasart W, et al. Differential binding with ERalpha and ERbeta of the phytoestrogen-rich plant Pueraria mirifica[J]. Braz J Med Biol Res, 2010, 43 (2): 195.
16. 2011, 27(10):1451.
17. Ang E S, Yang X, Chen H, et al. Naringin abrogates osteoclas-togenesis and bone resorption via the inhibition of RANKL-in- duced NF-kappaB and ERK activation [J]. FEBS Lett, 2011, 585(17): 2755.
18. Wu J B, Fong Y C, Tsai H Y, et al. Naringin-induced bone morphogenetic protein-2 expression via PI3K, Akt, c-Fos/c-Jun and AP-1 pathway in osteoblasts[J]. Eur J Pharmacol, 2008, 588(2/3): 333.