Lactosylated gramicidin-based lipid nanoparticles (Lac-GLN) for targeted delivery of anti-miR-155 to hepatocellular carcinoma

Journal of Controlled Release

Volumn 168, Issue 3, 2013, Pages 251-261

  Zhang, Mengzi ^a   Zhou, Xiaoju ^a,b   Wang, Bo ^a   Yung, Bryant C ^a   Lee, Ly J ^a,c   Ghoshal, Kalpana ^a   Lee, Robert J ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b WUHAN UNIVERSITY   (China)

^c Ohio State University   (United States)

Author keywords

Asialoglycoprotein receptor; Drug targeting; Gramicidin; Hepatocellular carcinoma; Nanoparticles

Indexed keywords

ASIALOGLYCOPROTEIN RECEPTORS; DRUG-TARGETING; ENCAPSULATION EFFICIENCY; GRAMICIDIN; HEPATOCELLULAR CARCINOMA; INTRAVENOUS ADMINISTRATION; INTRAVENOUS INJECTIONS; PHOSPHATIDYLETHANOLAMINE;

ENCAPSULATION; LIPOSOMES; RNA; ZETA POTENTIAL;

NANOPARTICLES;

CCAAT ENHANCER BINDING PROTEIN BETA; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; GRAMICIDIN; GRAMICIDIN A; LACTOSYLATED GRAMICIDIN BASED LIPID NANOPARTICLE; LIPOFECTAMINE; MICRORNA 155; N LACTOBIONYL DIOLEOYL PHOSPHATIDYLETHANOLAMINE; NANOPARTICLE; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; GENE EXPRESSION; HUMAN; HUMAN CELL; LIVER CELL; LIVER CELL CARCINOMA; MALE; MOUSE; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; UPREGULATION; ZETA POTENTIAL;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIBODIES; CARBOCYANINES; CCAAT-ENHANCER-BINDING PROTEINS; CELL LINE, TUMOR; CELL SURVIVAL; DRUG CARRIERS; FLUORESCENT DYES; FORKHEAD TRANSCRIPTION FACTORS; GRAMICIDIN; HEP G2 CELLS; HUMANS; LACTOSE; LIPIDS; MALE; MICE; MICE, INBRED C57BL; MICRORNAS; NANOPARTICLES; TISSUE DISTRIBUTION;

EID: 84877058809     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.03.020     Document Type: Article

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