Mechanism of alkoxy groups substitution by Grignard reagents on aromatic rings and experimental verification of theoretical predictions of anomalous reactions

Journal of the American Chemical Society

Volumn 135, Issue 17, 2013, Pages 6633-6642

  Jiménez Osés, Gonzalo ^a   Brockway, Anthony J ^b   Shaw, Jared T ^b   Houk, K N ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC ESTERS; AROMATIC RINGS; CARBONYL GROUPS; COMPUTATIONAL SYSTEM; EXPERIMENTAL VERIFICATION; GRIGNARD REAGENT; LEAVING GROUPS; TRANSITION STATE;

ESTERIFICATION; ESTERS; FORECASTING; KETONES; MAGNESIUM;

AROMATIC COMPOUNDS;

ALDEHYDE; ALKOXY GROUP; ALKYL GROUP; AROMATIC COMPOUND; CARBON; CARBONYL DERIVATIVE; ESTER; GRIGNARD REAGENT; KETONE; MAGNESIUM; UNCLASSIFIED DRUG;

ARTICLE; CALCULATION; NUCLEOPHILICITY; PREDICTION; SUBSTITUTION REACTION;

ALDEHYDES; CHELATING AGENTS; COMPUTER SIMULATION; ENERGY TRANSFER; ESTERS; HYDROCARBONS, AROMATIC; INDICATORS AND REAGENTS; KETONES; MAGNESIUM; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION;

EID: 84877049847     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja4015937     Document Type: Article

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