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Volumn 203, Issue 3, 2013, Pages 556-564

Bisphenol A affects androgen receptor function via multiple mechanisms

Author keywords

Androgen receptor; Bisphenol A and related compounds; Imaging analysis; qHTS; Transfection

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; ANDROGEN RECEPTOR; ANDROGEN RECEPTOR ANTAGONIST; ENHANCED GREEN FLUORESCENT PROTEIN; ESTROGEN RECEPTOR ALPHA; HORMONE RECEPTOR STIMULATING AGENT;

EID: 84877025952     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2013.03.013     Document Type: Article
Times cited : (165)

References (65)
  • 1
    • 84859493344 scopus 로고    scopus 로고
    • Soy, phytoestrogens and their impact on reproductive health
    • C.R. Cederroth, C. Zimmermann, and S. Nef Soy, phytoestrogens and their impact on reproductive health Mol. Cell. Endocrinol. 355 2012 192 200
    • (2012) Mol. Cell. Endocrinol. , vol.355 , pp. 192-200
    • Cederroth, C.R.1    Zimmermann, C.2    Nef, S.3
  • 3
    • 84859495274 scopus 로고    scopus 로고
    • Regional differences and temporal trends in male reproductive health disorders: Semen quality may be a sensitive marker of environmental exposures
    • L. Nordkap, U.N. Joensen, M. Blomberg Jensen, and N. Jorgensen Regional differences and temporal trends in male reproductive health disorders: semen quality may be a sensitive marker of environmental exposures Mol. Cell. Endocrinol. 355 2012 221 230
    • (2012) Mol. Cell. Endocrinol. , vol.355 , pp. 221-230
    • Nordkap, L.1    Joensen, U.N.2    Blomberg Jensen, M.3    Jorgensen, N.4
  • 4
    • 84859515807 scopus 로고    scopus 로고
    • Cryptorchidism and endocrine disrupting chemicals
    • H.E. Virtanen, and A. Adamsson Cryptorchidism and endocrine disrupting chemicals Mol. Cell. Endocrinol. 355 2012 208 220
    • (2012) Mol. Cell. Endocrinol. , vol.355 , pp. 208-220
    • Virtanen, H.E.1    Adamsson, A.2
  • 6
    • 0036825488 scopus 로고    scopus 로고
    • Environmental estrogens: Roles in male reproductive tract problems and in breast cancer
    • S. Safe Environmental estrogens: roles in male reproductive tract problems and in breast cancer Rev. Environ. Health. 17 2002 253 262 (Pubitemid 36222132)
    • (2002) Reviews on Environmental Health , vol.17 , Issue.4 , pp. 253-262
    • Safe, S.H.1
  • 8
    • 33645220243 scopus 로고    scopus 로고
    • Semen quality in fertile US men in relation to geographical area and pesticide exposure
    • discussion 105-108
    • S.H. Swan Semen quality in fertile US men in relation to geographical area and pesticide exposure Int. J. Androl. 29 2006 62 68 discussion 105-108
    • (2006) Int. J. Androl. , vol.29 , pp. 62-68
    • Swan, S.H.1
  • 9
    • 0035004535 scopus 로고    scopus 로고
    • Testicular dysgenesis syndrome: An increasingly common developmental disorder with environmental aspects
    • N.E. Skakkebaek, E. Rajpert-De Meyts, and K.M. Main Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects Hum. Reprod. 16 2001 972 978 (Pubitemid 32451837)
    • (2001) Human Reproduction , vol.16 , Issue.5 , pp. 972-978
    • Skakkebaek, N.E.1    Rajpert-De Meyts, E.2    Main, K.M.3
  • 10
    • 79961058104 scopus 로고    scopus 로고
    • Disruption of androgen receptor signaling in males by environmental chemicals
    • D.C. Luccio-Camelo, and G.S. Prins Disruption of androgen receptor signaling in males by environmental chemicals J. Steroid Biochem. Mol. Biol. 127 2011 74 82
    • (2011) J. Steroid Biochem. Mol. Biol. , vol.127 , pp. 74-82
    • Luccio-Camelo, D.C.1    Prins, G.S.2
  • 12
    • 1842434975 scopus 로고    scopus 로고
    • Environmental anti-androgens and male reproductive health: Focus on phthalates and testicular dysgenesis syndrome
    • J.S. Fisher Environmental anti-androgens and male reproductive health: focus on phthalates and testicular dysgenesis syndrome Reproduction 127 2004 305 315 (Pubitemid 38425690)
    • (2004) Reproduction , vol.127 , Issue.3 , pp. 305-315
    • Fisher, J.S.1
  • 14
    • 3042540196 scopus 로고    scopus 로고
    • Molecular mechanisms of androgen receptor-mediated gene regulation: Structure-function analysis of the AF-1 domain
    • DOI 10.1677/erc.0.0110281
    • I.J. McEwan Molecular mechanisms of androgen receptor-mediated gene regulation: structure-function analysis of the AF-1 domain Endocr. Relat. Cancer 11 2004 281 293 (Pubitemid 38842411)
    • (2004) Endocrine-Related Cancer , vol.11 , Issue.2 , pp. 281-293
    • McEwan, I.J.1
  • 15
    • 20444470999 scopus 로고    scopus 로고
    • Screening for androgen receptor activities in 253 industrial chemicals by in vitro reporter gene assays using AR-EcoScreen™ cells
    • DOI 10.1016/j.tiv.2005.04.009, PII S0887233305000706
    • N. Araki, K. Ohno, M. Nakai, M. Takeyoshi, and M. Iida Screening for androgen receptor activities in 253 industrial chemicals by in vitro reporter gene assays using AR-EcoScreen cells Toxicol. in Vitro 19 2005 831 842 (Pubitemid 40828778)
    • (2005) Toxicology in Vitro , vol.19 , Issue.6 , pp. 831-842
    • Araki, N.1    Ohno, K.2    Nakai, M.3    Takeyoshi, M.4    Iida, M.5
  • 17
    • 10044236969 scopus 로고    scopus 로고
    • Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells
    • H. Kojima, E. Katsura, S. Takeuchi, K. Niiyama, and K. Kobayashi Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells Environ. Health Perspect. 112 2004 524 531 (Pubitemid 38500039)
    • (2004) Environmental Health Perspectives , vol.112 , Issue.5 , pp. 524-531
    • Kojima, H.1    Katsura, E.2    Takeuchi, S.3    Niiyama, K.4    Kobayashi, K.5
  • 19
    • 43149089371 scopus 로고    scopus 로고
    • Screening of 397 chemicals and development of a quantitative structure-activity relationship model for androgen receptor antagonism
    • DOI 10.1021/tx7002382
    • A.M. Vinggaard, J. Niemela, E.B. Wedebye, and G.E. Jensen Screening of 397 chemicals and development of a quantitative structure-activity relationship model for androgen receptor antagonism Chem. Res. Toxicol. 21 2008 813 823 (Pubitemid 351644559)
    • (2008) Chemical Research in Toxicology , vol.21 , Issue.4 , pp. 813-823
    • Vinggaard, A.M.1    Niemela, J.2    Wedebye, E.B.3    Jensen, G.E.4
  • 21
    • 84862017941 scopus 로고    scopus 로고
    • Role of environmental chemicals in diabetes and obesity: A national toxicology program workshop review
    • K.A. Thayer, J.J. Heindel, J.R. Bucher, and M.A. Gallo Role of environmental chemicals in diabetes and obesity: a national toxicology program workshop review Environ. Health Perspect 120 2012 779 789
    • (2012) Environ. Health Perspect , vol.120 , pp. 779-789
    • Thayer, K.A.1    Heindel, J.J.2    Bucher, J.R.3    Gallo, M.A.4
  • 23
    • 39749187628 scopus 로고    scopus 로고
    • Exposure of the US population to bisphenol A and 4-tertiary-octylphenol: 2003-2004
    • A.M. Calafat, X. Ye, L.Y. Wong, J.A. Reidy, and L.L. Needham Exposure of the US population to bisphenol A and 4-tertiary-octylphenol: 2003-2004 Environ. Health Perspect. 116 2008 39 44
    • (2008) Environ. Health Perspect. , vol.116 , pp. 39-44
    • Calafat, A.M.1    Ye, X.2    Wong, L.Y.3    Reidy, J.A.4    Needham, L.L.5
  • 25
    • 85046980335 scopus 로고    scopus 로고
    • Bisphenol A and adult disease: Making sense of fragmentary data and competing inferences
    • D. Melzer, and T. Galloway Bisphenol A and adult disease: making sense of fragmentary data and competing inferences Ann. Intern. Med. 155 2011 392 394
    • (2011) Ann. Intern. Med. , vol.155 , pp. 392-394
    • Melzer, D.1    Galloway, T.2
  • 27
    • 79960980803 scopus 로고    scopus 로고
    • Bisphenol A: An endocrine disruptor with widespread exposure and multiple effects
    • B.S. Rubin Bisphenol A: an endocrine disruptor with widespread exposure and multiple effects J. Steroid Biochem. Mol. Biol. 127 2011 27 34
    • (2011) J. Steroid Biochem. Mol. Biol. , vol.127 , pp. 27-34
    • Rubin, B.S.1
  • 28
    • 38049080345 scopus 로고    scopus 로고
    • Endocrine-disrupting potential of bisphenol A, bisphenol A dimethacrylate, 4-n-nonylphenol, and 4-n-octylphenol in vitro: New data and a brief review
    • E.C. Bonefeld-Jorgensen, M. Long, M.V. Hofmeister, and A.M. Vinggaard Endocrine-disrupting potential of bisphenol A, bisphenol A dimethacrylate, 4-n-nonylphenol, and 4-n-octylphenol in vitro: new data and a brief review Environ. Health Perspect. 115 Suppl. 1 2007 69 76
    • (2007) Environ. Health Perspect. , vol.115 , Issue.SUPPL. 1 , pp. 69-76
    • Bonefeld-Jorgensen, E.C.1    Long, M.2    Hofmeister, M.V.3    Vinggaard, A.M.4
  • 29
    • 0031656115 scopus 로고    scopus 로고
    • Several environmental oestrogens are also anti-androgens
    • P. Sohoni, and J.P. Sumpter Several environmental oestrogens are also anti-androgens J. Endocrinol. 158 1998 327 339 (Pubitemid 28407540)
    • (1998) Journal of Endocrinology , vol.158 , Issue.3 , pp. 327-339
    • Sohoni, P.1    Sumpter, J.P.2
  • 30
    • 33751318449 scopus 로고    scopus 로고
    • Antiandrogenic activity of pyrethroid pesticides and their metabolite in reporter gene assay
    • DOI 10.1016/j.chemosphere.2006.05.059, PII S0045653506007351
    • H. Sun, X.L. Xu, L.C. Xu, L. Song, X. Hong, J.F. Chen, L.B. Cui, and X.R. Wang Antiandrogenic activity of pyrethroid pesticides and their metabolite in reporter gene assay Chemosphere 66 2007 474 479 (Pubitemid 44802881)
    • (2007) Chemosphere , vol.66 , Issue.3 , pp. 474-479
    • Sun, H.1    Xu, X.-L.2    Xu, L.-C.3    Song, L.4    Hong, X.5    Chen, J.-F.6    Cui, L.-B.7    Wang, X.-R.8
  • 32
    • 12344333360 scopus 로고    scopus 로고
    • Bisphenol-A, an environmental contaminant that acts as a thyroid hormone receptor antagonist in vitro, increases serum thyroxine, and alters RC3/neurogranin expression in the developing rat brain
    • DOI 10.1210/en.2004-1018
    • R.T. Zoeller, R. Bansal, and C. Parris Bisphenol-A, an environmental contaminant that acts as a thyroid hormone receptor antagonist in vitro, increases serum thyroxine, and alters RC3/neurogranin expression in the developing rat brain Endocrinology 146 2005 607 612 (Pubitemid 40129816)
    • (2005) Endocrinology , vol.146 , Issue.2 , pp. 607-612
    • Zoeller, R.T.1    Bansal, R.2    Parris, C.3
  • 33
    • 78649680619 scopus 로고    scopus 로고
    • Bisphenol-A can bind to human glucocorticoid receptor as an agonist: An in silico study
    • G.K. Prasanth, L.M. Divya, and C. Sadasivan Bisphenol-A can bind to human glucocorticoid receptor as an agonist: an in silico study J. Appl. Toxicol. 30 2010 769 774
    • (2010) J. Appl. Toxicol. , vol.30 , pp. 769-774
    • Prasanth, G.K.1    Divya, L.M.2    Sadasivan, C.3
  • 34
    • 40949108026 scopus 로고    scopus 로고
    • Direct evidence revealing structural elements essential for the high binding ability of bisphenol A to human estrogen-related receptor-gamma
    • H. Okada, T. Tokunaga, X. Liu, S. Takayanagi, A. Matsushima, and Y. Shimohigashi Direct evidence revealing structural elements essential for the high binding ability of bisphenol A to human estrogen-related receptor-gamma Environ. Health Perspect. 116 2008 32 38
    • (2008) Environ. Health Perspect. , vol.116 , pp. 32-38
    • Okada, H.1    Tokunaga, T.2    Liu, X.3    Takayanagi, S.4    Matsushima, A.5    Shimohigashi, Y.6
  • 35
    • 84865226393 scopus 로고    scopus 로고
    • Estrogen-related receptor gamma modulates energy metabolism target genes in human trophoblast
    • D. Poidatz, E. Dos Santos, A. Brule, P. De Mazancourt, and M.N. Dieudonne Estrogen-related receptor gamma modulates energy metabolism target genes in human trophoblast Placenta 33 2012 688 695
    • (2012) Placenta , vol.33 , pp. 688-695
    • Poidatz, D.1    Dos Santos, E.2    Brule, A.3    De Mazancourt, P.4    Dieudonne, M.N.5
  • 36
    • 77951664611 scopus 로고    scopus 로고
    • In vitro study of organization for economic co-operation and development (OECD) endocrine disruptor screening and testing methods- establishment of a recombinant rat androgen receptor (rrAR) binding assay
    • T.S. Kim, C.Y. Yoon, K.K. Jung, S.S. Kim, I.H. Kang, J.H. Baek, M.S. Jo, H.S. Kim, and T.S. Kang In vitro study of organization for economic co-operation and development (OECD) endocrine disruptor screening and testing methods- establishment of a recombinant rat androgen receptor (rrAR) binding assay J. Toxicol. Sci. 35 2010 239 243
    • (2010) J. Toxicol. Sci. , vol.35 , pp. 239-243
    • Kim, T.S.1    Yoon, C.Y.2    Jung, K.K.3    Kim, S.S.4    Kang, I.H.5    Baek, J.H.6    Jo, M.S.7    Kim, H.S.8    Kang, T.S.9
  • 37
    • 0037205916 scopus 로고    scopus 로고
    • Phenylphenols, biphenols, bisphenol-A and 4-tert-octylphenol exhibit α and β estrogen activities and antiandrogen activity in reporter cell lines
    • DOI 10.1016/S0303-7207(02)00094-1, PII S0303720702000941
    • F. Paris, P. Balaguer, B. Terouanne, N. Servant, C. Lacoste, J.P. Cravedi, J.C. Nicolas, and C. Sultan Phenylphenols, biphenols, bisphenol-A and 4-tert-octylphenol exhibit alpha and beta estrogen activities and antiandrogen activity in reporter cell lines Mol. Cell. Endocrinol. 193 2002 43 49 (Pubitemid 34823606)
    • (2002) Molecular and Cellular Endocrinology , vol.193 , Issue.1-2 , pp. 43-49
    • Paris, F.1    Balaguer, P.2    Terouanne, B.3    Servant, N.4    Lacoste, C.5    Cravedi, J.-P.6    Nicolas, J.-C.7    Sultan, C.8
  • 38
    • 0041380903 scopus 로고    scopus 로고
    • Antiandrogenic effects of bisphenol A and nonylphenol on the function of androgen receptor
    • DOI 10.1093/toxsci/kfg150
    • H.J. Lee, S. Chattopadhyay, E.Y. Gong, R.S. Ahn, and K. Lee Antiandrogenic effects of bisphenol A and nonylphenol on the function of androgen receptor Toxicol. Sci. 75 2003 40 46 (Pubitemid 37098734)
    • (2003) Toxicological Sciences , vol.75 , Issue.1 , pp. 40-46
    • Lee, H.J.1    Chattopadhyay, S.2    Gong, E.-Y.3    Ahn, R.S.4    Lee, K.5
  • 39
    • 28244470719 scopus 로고    scopus 로고
    • Evaluation of androgen receptor transcriptional activities of bisphenol A, octylphenol and nonylphenol in vitro
    • DOI 10.1016/j.tox.2005.08.006, PII S0300483X05003719
    • L.C. Xu, H. Sun, J.F. Chen, Q. Bian, J. Qian, L. Song, and X.R. Wang Evaluation of androgen receptor transcriptional activities of bisphenol A, octylphenol and nonylphenol in vitro Toxicology 216 2005 197 203 (Pubitemid 41712009)
    • (2005) Toxicology , vol.216 , Issue.2-3 , pp. 197-203
    • Xu, L.-C.1    Sun, H.2    Chen, J.-F.3    Bian, Q.4    Qian, J.5    Song, L.6    Wang, X.-R.7
  • 41
    • 0021187553 scopus 로고
    • Methyltrienolone (R1881) is not aromatized by placental microsomes or rat hypothalamic homogenates
    • DOI 10.1016/0022-4731(84)90360-1
    • C.H. Doering, and P.T. Leyra Methyltrienolone (R1881) is not aromatized by placental microsomes or rat hypothalamic homogenates J. Steroid Biochem. 20 1984 1157 1162 (Pubitemid 14108616)
    • (1984) Journal of Steroid Biochemistry , vol.20 , Issue.5 , pp. 1157-1162
    • Doering, C.H.1    Leyra, P.T.2
  • 42
    • 0017445819 scopus 로고
    • The mechanism of action of androgens
    • W.I. Mainwaring The mechanism of action of androgens Monogr. Endocrinol. 10 1977 1 178
    • (1977) Monogr. Endocrinol. , vol.10 , pp. 1-178
    • Mainwaring, W.I.1
  • 43
    • 0035813090 scopus 로고    scopus 로고
    • Coregulator codes of transcriptional regulation by nuclear receptors
    • M.G. Rosenfeld, and C.K. Glass Coregulator codes of transcriptional regulation by nuclear receptors J. Biol. Chem. 276 2001 36865 36868
    • (2001) J. Biol. Chem. , vol.276 , pp. 36865-36868
    • Rosenfeld, M.G.1    Glass, C.K.2
  • 45
    • 56249084597 scopus 로고    scopus 로고
    • Androgen receptor functional analyses by high throughput imaging: Determination of ligand, cell cycle, and mutation-specific effects
    • A.T. Szafran, M. Szwarc, M. Marcelli, and M.A. Mancini Androgen receptor functional analyses by high throughput imaging: determination of ligand, cell cycle, and mutation-specific effects PLoS One 3 2008 e3605
    • (2008) PLoS One , vol.3 , pp. 3605
    • Szafran, A.T.1    Szwarc, M.2    Marcelli, M.3    Mancini, M.A.4
  • 46
    • 0033802882 scopus 로고    scopus 로고
    • Interaction of methoxychlor and related compounds with estrogen receptor alpha and beta, and androgen receptor: Structure-activity studies
    • K.W. Gaido, S.C. Maness, D.P. McDonnell, S.S. Dehal, D. Kupfer, and S. Safe Interaction of methoxychlor and related compounds with estrogen receptor alpha and beta, and androgen receptor: structure-activity studies Mol. Pharmacol. 58 2000 852 858
    • (2000) Mol. Pharmacol. , vol.58 , pp. 852-858
    • Gaido, K.W.1    Maness, S.C.2    McDonnell, D.P.3    Dehal, S.S.4    Kupfer, D.5    Safe, S.6
  • 48
    • 0028904382 scopus 로고
    • Identification of two transcription activation units in the N-terminal domain of the human androgen receptor
    • G. Jenster, H.A. van der Korput, J. Trapman, and A.O. Brinkmann Identification of two transcription activation units in the N-terminal domain of the human androgen receptor J. Biol. Chem. 270 1995 7341 7346
    • (1995) J. Biol. Chem. , vol.270 , pp. 7341-7346
    • Jenster, G.1    Van Der Korput, H.A.2    Trapman, J.3    Brinkmann, A.O.4
  • 49
    • 82655174034 scopus 로고    scopus 로고
    • Structural features discriminate androgen receptor N/C terminal and coactivator interactions
    • E.B. Askew, J.T. Minges, A.T. Hnat, and E.M. Wilson Structural features discriminate androgen receptor N/C terminal and coactivator interactions Mol. Cell. Endocrinol. 348 2012 403 410
    • (2012) Mol. Cell. Endocrinol. , vol.348 , pp. 403-410
    • Askew, E.B.1    Minges, J.T.2    Hnat, A.T.3    Wilson, E.M.4
  • 51
    • 0031039888 scopus 로고    scopus 로고
    • Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors and α and β
    • DOI 10.1210/en.138.3.863
    • G.G. Kuiper, B. Carlsson, K. Grandien, E. Enmark, J. Haggblad, S. Nilsson, and J.A. Gustafsson Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta Endocrinology 138 1997 863 870 (Pubitemid 27089735)
    • (1997) Endocrinology , vol.138 , Issue.3 , pp. 863-870
    • Kuiper, G.G.J.M.1    Carlsson, B.2    Grandien, K.3    Enmark, E.4    Haggblad, J.5    Nilsson, S.6    Gustafsson, J.-A.7
  • 52
    • 0034680924 scopus 로고    scopus 로고
    • Differential effects of xenoestrogens on coactivator recruitment by estrogen receptor (ER) alpha and ERbeta
    • E.J. Routledge, R. White, M.G. Parker, and J.P. Sumpter Differential effects of xenoestrogens on coactivator recruitment by estrogen receptor (ER) alpha and ERbeta J. Biol. Chem. 275 2000 35986 35993
    • (2000) J. Biol. Chem. , vol.275 , pp. 35986-35993
    • Routledge, E.J.1    White, R.2    Parker, M.G.3    Sumpter, J.P.4
  • 53
    • 84864148571 scopus 로고    scopus 로고
    • Differential Estrogenic Actions of Endocrine-Disrupting Chemicals Bisphenol A, Bisphenol AF, and Zearalenone through Estrogen Receptor alpha and beta in Vitro
    • Y. Li, K.A. Burns, Y. Arao, C.J. Luh, and K.S. Korach Differential Estrogenic Actions of Endocrine-Disrupting Chemicals Bisphenol A, Bisphenol AF, and Zearalenone through Estrogen Receptor alpha and beta in Vitro Environ. Health Perspect. 120 2012 1029 1035
    • (2012) Environ. Health Perspect. , vol.120 , pp. 1029-1035
    • Li, Y.1    Burns, K.A.2    Arao, Y.3    Luh, C.J.4    Korach, K.S.5
  • 54
    • 0035958949 scopus 로고    scopus 로고
    • The subnuclear three-dimensional image analysis of androgen receptor fused to green fluorescence protein
    • A. Tomura, K. Goto, H. Morinaga, M. Nomura, T. Okabe, T. Yanase, R. Takayanagi, and H. Nawata The subnuclear three-dimensional image analysis of androgen receptor fused to green fluorescence protein J. Biol. Chem. 276 2001 28395 28401
    • (2001) J. Biol. Chem. , vol.276 , pp. 28395-28401
    • Tomura, A.1    Goto, K.2    Morinaga, H.3    Nomura, M.4    Okabe, T.5    Yanase, T.6    Takayanagi, R.7    Nawata, H.8
  • 55
    • 43149125406 scopus 로고    scopus 로고
    • Structural basis for the nuclear import of the human androgen receptor
    • DOI 10.1242/jcs.022103
    • M.L. Cutress, H.C. Whitaker, I.G. Mills, M. Stewart, and D.E. Neal Structural basis for the nuclear import of the human androgen receptor J. Cell Sci. 121 2008 957 968 (Pubitemid 351639415)
    • (2008) Journal of Cell Science , vol.121 , Issue.7 , pp. 957-968
    • Cutress, M.L.1    Whitaker, H.C.2    Mills, I.G.3    Stewart, M.4    Neal, D.E.5
  • 56
    • 0034465595 scopus 로고    scopus 로고
    • Dynamics of intracellular movement and nucleocytoplasmic recycling of the ligand-activated androgen receptor in living cells
    • DOI 10.1210/me.14.8.1162
    • R.K. Tyagi, Y. Lavrovsky, S.C. Ahn, C.S. Song, B. Chatterjee, and A.K. Roy Dynamics of intracellular movement and nucleocytoplasmic recycling of the ligand-activated androgen receptor in living cells Mol. Endocrinol. 14 2000 1162 1174 (Pubitemid 32260478)
    • (2000) Molecular Endocrinology , vol.14 , Issue.8 , pp. 1162-1174
    • Tyagi, R.K.1    Lavrovsky, Y.2    Ahn, S.C.3    Song, C.S.4    Chatterjee, B.5    Roy, A.K.6
  • 58
    • 0036559993 scopus 로고    scopus 로고
    • The xenoestrogen bisphenol A induces inappropriate androgen receptor activation and mitogenesis in prostatic adenocarcinoma cells
    • Y.B. Wetherill, C.E. Petre, K.R. Monk, A. Puga, and K.E. Knudsen The xenoestrogen bisphenol A induces inappropriate androgen receptor activation and mitogenesis in prostatic adenocarcinoma cells Mol. Cancer Ther. 1 2002 515 524
    • (2002) Mol. Cancer Ther. , vol.1 , pp. 515-524
    • Wetherill, Y.B.1    Petre, C.E.2    Monk, K.R.3    Puga, A.4    Knudsen, K.E.5
  • 60
    • 55749094858 scopus 로고    scopus 로고
    • Structural basis for nuclear receptor corepressor recruitment by antagonist-liganded androgen receptor
    • M.C. Hodgson, H.C. Shen, A.N. Hollenberg, and S.P. Balk Structural basis for nuclear receptor corepressor recruitment by antagonist-liganded androgen receptor Mol. Cancer Ther. 7 2008 3187 3194
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 3187-3194
    • Hodgson, M.C.1    Shen, H.C.2    Hollenberg, A.N.3    Balk, S.P.4
  • 63
    • 0142125911 scopus 로고    scopus 로고
    • Hsp90 as a Therapeutic Target in Prostate Cancer
    • DOI 10.1016/S0093-7754(03)00346-4
    • D.B. Solit, H.I. Scher, and N. Rosen Hsp90 as a therapeutic target in prostate cancer Semin. Oncol. 30 2003 709 716 (Pubitemid 37296795)
    • (2003) Seminars in Oncology , vol.30 , Issue.5 , pp. 709-716
    • Solit, D.B.1    Scher, H.I.2    Rosen, N.3
  • 64
    • 33846854438 scopus 로고    scopus 로고
    • The Expanding Role of Epigenetics in the Development, Diagnosis and Treatment of Prostate Cancer and Benign Prostatic Hyperplasia
    • DOI 10.1016/j.juro.2006.10.063, PII S0022534706027376
    • J.R. Dobosy, J.L. Roberts, V.X. Fu, and D.F. Jarrard The expanding role of epigenetics in the development, diagnosis and treatment of prostate cancer and benign prostatic hyperplasia J. Urol. 177 2007 822 831 (Pubitemid 46223571)
    • (2007) Journal of Urology , vol.177 , Issue.3 , pp. 822-831
    • Dobosy, J.R.1    Roberts, J.L.W.2    Fu, V.X.3    Jarrard, D.F.4
  • 65
    • 7944234374 scopus 로고    scopus 로고
    • HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability
    • DOI 10.1016/j.ccr.2004.09.031, PII S1535610804003034
    • I.K. Mellinghoff, I. Vivanco, A. Kwon, C. Tran, J. Wongvipat, and C.L. Sawyers HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability Cancer Cell 6 2004 517 527 (Pubitemid 39469987)
    • (2004) Cancer Cell , vol.6 , Issue.5 , pp. 517-527
    • Mellinghoff, I.K.1    Vivanco, I.2    Kwon, A.3    Tran, C.4    Wongvipat, J.5    Sawyers, C.L.6


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