Screening for androgen receptor activities in 253 industrial chemicals by in vitro reporter gene assays using AR-EcoScreen™ cells

Toxicology in Vitro

Volumn 19, Issue 6, 2005, Pages 831-842

  Araki, Naohiro ^a   Ohno, Ken ^a   Nakai, Makoto ^b   Takeyoshi, Masahiro ^c   Iida, Mitsuru ^a  

^a OTSUKA PHARMACEUTICAL CO LTD   (Japan)

^b CHEMICALS EVALUATION AND RESEARCH INSTITUTE   (Japan)

^c CERI   (Japan)

Author keywords

Androgen receptor; AR EcoScreen ; Endocrine disruptor; High throughput screening; Reporter gene assay

Indexed keywords

3,3' DICHLOROBENZIDINE; ANDROGEN RECEPTOR; ANDROSTANOLONE; ANTHRAQUINONE DERIVATIVE; ANTIANDROGEN; BENZALDEHYDE DERIVATIVE; DIPHENYLAMINE DERIVATIVE; HORMONE RECEPTOR STIMULATING AGENT; HYDRAZINE DERIVATIVE; INDUSTRIAL CHEMICAL; PHENOL DERIVATIVE; PROPANE; PYRIDINE DERIVATIVE;

ARTICLE; REPORTER GENE; SCREENING TEST;

ANDROGEN ANTAGONISTS; ANIMALS; BINDING, COMPETITIVE; CELL LINE; CHO CELLS; CRICETINAE; DIHYDROTESTOSTERONE; DIMETHYL SULFOXIDE; GENES, REPORTER; GENETIC ENGINEERING; LUCIFERASES; MALE; ORGANIC CHEMICALS; PILOT PROJECTS; RATS; RECEPTORS, ANDROGEN; REPRODUCIBILITY OF RESULTS; TESTOSTERONE CONGENERS; TOXICITY TESTS; TRANSFECTION;

EID: 20444470999     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2005.04.009     Document Type: Article

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