Intrinsic defects in CD8 T cells with aging contribute to impaired primary antiviral responses

Experimental Gerontology

Volumn 48, Issue 6, 2013, Pages 579-586

  Jiang, Jiu ^a   Fisher, Erin M ^a   Murasko, Donna M ^a  

^a DREXEL UNIVERSITY   (United States)

Author keywords

Aging; Defect; Intrinsic; T cells; Viral

Indexed keywords

CD69 ANTIGEN; GAMMA INTERFERON; HERMES ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA;

ADOPTIVE TRANSFER; AGE DISTRIBUTION; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ANTIGEN PURIFICATION; ARTICLE; CD8+ T LYMPHOCYTE; CELL CULTURE; CELL EXPANSION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; IN VITRO STUDY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS INFECTION; MOUSE; NONHUMAN; PHENOTYPE; PREDICTION; PRIORITY JOURNAL; VIRUS INFECTION;

ADOPTIVE TRANSFER; AGING; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; IMMUNITY, CELLULAR; IMMUNITY, INNATE; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, TRANSGENIC; SPLEEN;

LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MUS;

EID: 84877016468     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2013.02.027     Document Type: Article

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