Further evidence for the sleep-promoting effects of 5-HT2A receptor antagonists and demonstration of synergistic effects with the hypnotic, zolpidem in rats

Neuropharmacology

Volumn 70, Issue , 2013, Pages 19-26

  Griebel, Guy ^a   Beeské, Sandra ^a   Jacquet, Agnès ^a   Laufrais, Christian ^a   Alonso, Richard ^a   Decobert, Michel ^a   Avenet, Patrick ^a   Françon, Dominique ^a  

^a SANOFI   (France)

Author keywords

5 HT2A antagonist; EEG; Sleep maintenance; Zolpidem

Indexed keywords

AVE 8488; EPLIVANSERIN; SEROTONIN 2A ANTAGONIST; UNCLASSIFIED DRUG; VOLINANSERIN; ZOLPIDEM;

ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG POTENCY; DRUG POTENTIATION; DRUG RECEPTOR BINDING; ELECTROENCEPHALOGRAM; INSOMNIA; LATENT PERIOD; LOW DRUG DOSE; MALE; NONHUMAN; NONREM SLEEP; PRIORITY JOURNAL; RAT; SIGNAL PROCESSING; SLEEP INDUCTION; SLEEP WAKING CYCLE;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; FLUOROBENZENES; HYPNOTICS AND SEDATIVES; MALE; PHENOLS; PIPERIDINES; PYRIDINES; RATS; SEROTONIN ANTAGONISTS; SLEEP STAGES; WAKEFULNESS;

EID: 84876980834     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.12.008     Document Type: Article

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