High-dose versus low-dose octreotide in the treatment of acute pancreatitis: A randomized controlled trial

Peptides

Volumn 40, Issue , 2013, Pages 57-64

  Wang, Rui ^a   Yang, Fan ^a   Wu, Hao ^a   Wang, Yufang ^a   Huang, Zhiyin ^a   Hu, Bing ^a   Zhang, Mingguang ^a   Tang, Chengwei ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Acute pancreatitis; Inflammation; Octreotide; Somatostatin

Indexed keywords

INTERLEUKIN 6; OCTREOTIDE; SOMATOSTATIN; TUMOR NECROSIS FACTOR ALPHA;

ACUTE PANCREATITIS; ADULT; AGED; APACHE; ARTICLE; CONTROLLED STUDY; DRUG MEGADOSE; FEMALE; HUMAN; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SOMATOSTATIN BLOOD LEVEL; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

ADOLESCENT; ADULT; AGED; FEMALE; HUMANS; INFLAMMATION; INTERLEUKIN-6; MALE; MIDDLE AGED; OCTREOTIDE; PANCREATITIS; SOMATOSTATIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84876978857     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2012.12.018     Document Type: Article

References (56)

1. A. Al Samaraee, I.J. McCallum, P.E. Coyne, and K. Seymour Nutritional strategies in severe acute pancreatitis: a systematic review of the evidence Surgeon 8 2010 105 110 [PMID: 20303893]
2. A. Andoh, K. Hata, M. Shimada, S. Fujino, K. Tasaki, and S. Bamba Inhibitory effects of somatostatin on tumor necrosis factor-α-induced interleukin-6 secretion in human pancreatic periacinar myofibroblasts Int J Mol Med 10 2002 89 93 [PMID: 12060857]
3. A. Andriulli, G. Leandro, R. Clemente, V. Festa, N. Caruso, and V. Annese Meta-analysis of somatostatin, octreotide and gabexate mesilate in the therapy of acute pancreatitis Aliment Pharmacol Ther 12 1998 237 245 [PMID: 9570258]
4. Y. Bai, Y. Liu, L. Jia, H. Jiang, M. Ji, and N. Lv Severe acute pancreatitis in China: etiology and mortality in 1976 patients Pancreas 35 2007 232 237 [PMID: 17895843]
5. P.A. Banks, and M.L. Freeman The Practice Parameters Committee of the American College of Gastroenterology, Practice guidelines in acute pancreatitis Am J Gastroenterol 101 2006 2379 2400 [PMID: 17032204]
6. S.G. Barreto, C.J. Carati, A.C. Schloithe, J. Toouli, and G.T. Saccone Octreotide negates the benefit of galantide when used in the treatment of caerulein-induced acute pancreatitis in mice HPB (Oxford) 12 2010 403 411 [PMID: 20662791]
7. N. Beechey-Newman Controlled trial of high-dose octreotide in treatment of acute pancreatitis. Evidence of improvement in disease severity Dig Dis Sci 38 1993 644 647 [PMID: 8462363]
8. M. Bhatia, F.L. Wong, Y. Cao, H.Y. Lau, J. Huang, and P. Puneet Pathophysiology of acute pancreatitis Pancreatology 5 2005 132 144 [PMID: 15849484]
9. T.L. Bollen, H.C. van Santvoort, M.G. Besselink, M.S. van Leeuwen, K.D. Horvath, and P.C. Freeny The Atlanta classification of acute pancreatitis revisited Br J Surg 95 2008 6 21 [PMID: 17985333]
10. A.L. Buchman Side effects of corticosteroid therapy J Clin Gastroenterol 33 2001 289 294 [PMID: 11588541]
11. A. Carnovale, P.G. Rabitti, G. Manes, P. Esposito, L. Pacelli, and G. Uomo Mortality in acute pancreatitis: is it an early or a late event? JOP 6 2005 438 444 [PMID: 16186665]
12. C.C. Chen, S.S. Wang, S.H. Tsay, F.Y. Lee, S.L. Wu, and R.H. Lu Effects of high dose octreotide on retrograde bile salt-induced pancreatitis in rats Peptides 19 1998 543 547 [PMID: 9533643]
13. P. Chen, B. Hu, Q. Tan, L. Liu, D. Li, and C. Jiang Role of neurocrine somatostatin on sphincter of Oddi contractility and intestinal ischemia reperfusion-induced acute pancreatitis in macaques Neurogastroenterol Motil 22 2010 935 944 [PMID: 20497509]
14. S.T. Fan, E.C. Lai, F.P. Mok, C.M. Lo, S.S. Zheng, and J. Wong Prediction of the severity of acute pancreatitis Am J Surg 166 1993 262 268 [PMID: 8368436]
15. F. Fiedler, G. Jauernig, V. Keim, A. Richter, and H.J. Bender Octreotide treatment in patients with necrotizing pancreatitis and pulmonary failure Intensive Care Med 22 1996 909 915 [PMID: 8905425]
16. S.E. Greer, and K.W. Burchard Acute pancreatitis and critical illness: a pancreatic tale of hypoperfusion and inflammation Chest 136 2009 1413 1419 [PMID: 19892682]
17. P. Gregoric, A. Sijacki, S. Stankovic, D. Radenkovic, N. Ivancevic, and A. Karamarkovic SIRS score on admission and initial concentration of IL-6 as severe acute pancreatitis outcome predictors Hepatogastroenterology 57 2010 349 353 [PMID: 20583441]
18. O. Güler, S. Akturan, E. Kisli, I. Dolapçi, M. Caydere, and A. Akova Acute pancreatitis, bacterial translocation, and different octreotide regimens: an experimental study Surg Today 39 2009 876 883 [PMID: 19784727]
19. "Helping Patients Who Drink Too Much: A Clinician's Guide and Related Professional Support Resources", [online] Available: www.niaaa.nih.gov/guide.
20. O. Kaplan, D. Kaplan, E. Casif, A. Siegal, H. Paran, and E. Graf Effects of delayed administration of octreotide in acute experimental pancreatitis J Surg Res 62 1996 109 117 [PMID: 8606496]
21. A.A. Khan, D. Parekh, Y. Cho, R. Ruiz, R.R. Selby, and N. Jabbour Improved prediction of outcome in patients with severe acute pancreatitis by the APACHE II score at 48 h after hospital admission compared with the APACHE II score at admission. Acute Physiology and Chronic Health Evaluation Arch Surg 137 2002 1136 1140 [PMID: 12361419]
22. S.W. Lamberts, A.J. van der Lely, and L.J. Hofland New somatostatin analogs: will they fulfil old promises? Eur J Endocrinol 146 2002 701 705 [PMID: 11980627]
23. P.G. Lankisch, and M.M. Lerch Pharmacological prevention and treatment of acute pancreatitis: where are we now? Dig Dis 24 2006 148 159 [PMID: 16699273]
24. M. Larvin, and M.J. McMahon APACHE-II score for assessment and monitoring of acute pancreatitis Lancet 2 1989 201 205 [PMID: 2568529]
25. R. Lefering, R.J. Goris, E.J. van Nieuwenhoven, and E. Neugebauer Revision of the multiple organ failure score Langenbecks Arch Surg 387 2002 14 20 [PMID: 11981679]
26. J. Li, R. Wang, and C. Tang Somatostatin and octreotide on the treatment of acute pancreatitis-basic and clinical studies for three decades Curr Pharm Des 17 2011 1594 1601 [PMID: 21548873]
27. J. Marton, Z. Szasz, Z. Nagy, K. Jarmay, T. Takacs, and J. Lonovics Beneficial effect of octreotide treatment in acute pancreatitis in rats Int J Pancreatol 24 1998 203 210 [PMID: 9873955]
28. W.R. Matull, S.P. Pereira, and J.W. O'Donohue Biochemical markers of acute pancreatitis J Clin Pathol 59 2006 340 344 [PMID: 16567468]
29. C. McKay, J. Baxter, and C. Imrie A randomized, controlled trial of octreotide in the management of patients with acute pancreatitis Int J Pancreatol 21 1997 13 19 [PMID: 9127169]
30. J.P. Neoptolemos, E.A. Kemppainen, J.M. Mayer, J.M. Fitzpatrick, M.G. Raraty, and J. Slavin Early prediction of severity in acute pancreatitis by urinary trypsinogen activation peptide: a multicentre study Lancet 355 2000 1955 1960 [PMID: 10859041]
31. G.C. Nikou, T.P. Arnaoutis, E.J. Giamarellos-Bourboulis, O. Samolada, I. Vafiadis-Zouboulis, and N. Katsilambros The significance of the dosage adjustment of octreotide in the treatment of acute pancreatitis of moderate severity Hepatogastroenterology 48 2001 1754 1757 [PMID: 11813617]
32. G.C. Nikou, E.J. Giamarellos-Bourboulis, P. Grecka, Toumpanakis Ch, G. Giannikopoulos, and N. Katsilambros Effect of octreotide administration on serum interleukin-6 (IL-6) levels of patients with acute edematous pancreatitis Hepatogastroenterology 51 2004 599 602 [PMID: 15086213]
33. H. Paran, A. Mayo, D. Paran, D. Neufeld, I. Shwartz, and R. Zissin Octreotide treatment in patients with severe acute pancreatitis Dig Dis Sci 45 2000 2247 2251 [PMID: 11215748]
34. E. Pintér, Z. Helyes, and J. Szolcsányi Inhibitory effect of somatostatin on inflammation and nociception Pharmacol Ther 112 2006 440 456 [PMID: 16764934]
35. B. Rau, K. Baumgart, C.M. Krüger, M. Schilling, and H.G. Beger CC-chemokine activation in acute pancreatitis: enhanced release of monocyte chemoattractant protein-1 in patients with local and systemic complications Intensive Care Med 29 2003 622 629 [PMID: 12589535]
36. J.C. Reubi, B. Waser, R. Cescato, B. Gloor, C. Stettler, and E. Christ Internalized somatostatin receptor subtype 2 in neuroendocrine tumors of octreotide-treated patients J Clin Endocrinol Metab 95 2010 2343 2350 [PMID: 20228164]
37. R.M. Roumen, T.J. Schers, H.H. de Boer, and R.J. Goris Scoring systems for predicting outcome in acute hemorrhagic necrotizing pancreatitis Eur J Surg 158 1992 167 171 [PMID: 1356457]
38. A.K. Siriwardena, J.M. Mason, S. Balachandra, A. Bagul, S. Galloway, and L. Formela Randomized, double blind, placebo controlled trial of intravenous antioxidant (n-acetylcysteine, selenium, vitamin C) therapy in severe acute pancreatitis Gut 56 2007 1439 1444 [PMID: 17356040]
39. W.M. Steinberg, and S.E. Schlesselman Treatment of acute pancreatitis. Comparison of animal and human studies Gastroenterology 93 1987 1420 1427 [PMID: 2445620]
40. J. Szolcsányi, Z. Helyes, G. Oroszi, J. Németh, and E. Pintér Release of somatostatin and its role in the mediation of the anti-inflammatory effect induced by antidromic stimulation of sensory fibres of rat sciatic nerve Br J Pharmacol 123 1998 936 942 [PMID: 9535023]
41. C. Tang, C. Lan, C. Wang, and R. Liu Amelioration of the development of multiple organ dysfunction syndrome by somatostatin via suppression of intestinal mucosal mast cells Shock 23 2005 470 475 [PMID: 15834315]
42. H. Tian, X. Zhang, C. Wu, L. Chen, R. Ying, and J. Ye Effects of Baicalin and Octreotide on the serum TNF-α level and apoptosis in multiple organs of rats with severe acute pancreatitis Inflammation 32 2009 191 201 [PMID: 19387806]
43. W. Uhl, M.W. Büchler, P. Malfertheiner, H.G. Beger, G. Adler, and W. Gaus A randomized, double blind, multicentre trial of octreotide in moderate to severe acute pancreatitis Gut 45 1999 97 104 [PMID: 10369711]
44. UK Working Party on Acute Pancreatitis UK guidelines for the management of acute, pancreatitis Gut 54 2005 iii1 iii9 [PMID: 15831893]
45. H.C. van Santvoort, M.G. Besselink, A.C. de Vries, M.A. Boermeester, K. Fischer, and T.L. Bollen Early endoscopic retrograde cholangiopancreatography in predicted severe acute biliary pancreatitis: a prospective multicenter study Ann Surg 250 2009 68 75 [PMID: 19561460]
46. B. Waser, M.L. Tamma, R. Cescato, H.R. Maecke, and J.C. Reubi Highly efficient in vivo agonist-induced internalization of sst2 receptors in somatostatin target tissues J Nucl Med 50 2009 936 941 [PMID: 19443580]
47. J. Werner, W. Hartwig, W. Uhl, C. Müller, and M.W. Büchler Useful markers for predicting severity and monitoring progression of acute pancreatitis Pancreatology 3 2003 115 127 [PMID: 12748420]
48. A. Wilmer ICU management of severe acute pancreatitis Eur J Intern Med 15 2004 274 280 [PMID: 15450983]
49. C. Wilson, D.I. Heath, and C.W. Imrie Prediction of outcome in acute pancreatitis: a comparative study of APACHE II, clinical assessment and multiple factor scoring systems Br J Surg 77 1990 1260 1264 [PMID: 2253005]
50. G. Woeste, C. Wullstein, S. Meyer, K.H. Usadel, U.T. Hopt, and W.O. Bechstein Octreotide attenuates impaired microcirculation in postischemic pancreatitis when administered before induction of ischemia Transplantation 86 2008 961 967 [PMID: 18852663]
51. H. Wu, Y.Y. Deng, Y. Kang, M.H. Huang, L. Hu, and C.W. Tang Clinical implication of blood somatostatin determination in critically ill patients Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 21 2009 307 310 (Article in Chinese). [PMID: 19439122]
52. H. Wu, L. Liu, Q. Tan, C. Wang, M. Guo, and Y. Xie Somatostatin limits intestinal ischemia-reperfusion injury in macaques via suppression of TLR4-NF-kappaB cytokine pathway J Gastrointest Surg 13 2009 983 993 [PMID: 19184243]
53. X.N. Wu Guidelines for treatment of severe acute pancreatitis Hepatobiliary Pancreat Dis Int 1 2002 446 451 [PMID: 14607725]
54. F. Yang, H. Wu, Y.Q. Li, Z.S. Li, C.H. Wang, and J.L. Yang Prevention of severe acute pancreatitis with octreotide in obese patients: a prospective multi-center randomized controlled trial Pancreas 41 2012 1206 1212
55. X.P. Zhang, L. Zhang, P. Yang, R.P. Zhang, and Q.H. Cheng Protective effects of baicalin and octreotide on multiple organ injury in severe acute pancreatitis Dig Dis Sci 53 2008 581 591 [PMID: 17549629]
56. C. Zhou, J. Li, H.Y. Wang, and C. Tang Decreased somatostatin is related to the hypersensitivity of intestinal epithelia to LPS via up-regulated TLR4-TBK1 pathway in rats chronically exposed to ethanol Alcohol 43 2009 293 303 [PMID: 19375882]