Treatment with pioglitazone is associated with decreased preprandial ghrelin levels: A randomized clinical trial

Peptides

Volumn 40, Issue , 2013, Pages 89-92

  Taslimi, Shervin ^a   Esteghamati, Alireza ^a   Rashidi, Armin ^b   Tavakkoli, Hosein Moin ^a   Nakhjavani, Manouchehr ^a   Kebriaee Zadeh, Abbas ^c  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Ghrelin; Glucose tolerance; Leptin; Metformin

Indexed keywords

GHRELIN; GLUCOSE; HEMOGLOBIN A1C; METFORMIN; PIOGLITAZONE;

ARTICLE; BLOOD GLUCOSE MONITORING; BODY MASS; BODY WEIGHT; CONTROLLED STUDY; DIABETIC PATIENT; DRUG EFFECT; GLUCOSE BLOOD LEVEL; HEMOGLOBIN BLOOD LEVEL; HUMAN; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT DURATION; WEIGHT GAIN;

ADULT; BLOOD GLUCOSE; BODY WEIGHT; DIABETES MELLITUS, TYPE 2; FEMALE; GHRELIN; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN; LEPTIN; MALE; METFORMIN; MIDDLE AGED; THIAZOLIDINEDIONES;

EID: 84876960963     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2012.12.020     Document Type: Article

References (17)

1. American Diabetes Association, J.P. Bantle, J. Wylie-Rosett, A.L. Albright, C.M. Apovian, and N.G. Clark Nutrition recommendations and interventions for diabetes: a position statement of the American Diabetes Association Diabetes Care 31 2008 S61 S78
2. H. Ariyasu, K. Takaya, T. Tagami, Y. Ogawa, K. Hosoda, and T. Akamizu Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans J Clin Endocrinol Metab 86 2001 4753 4758
3. M. Bassi, J.M. do Carmo, J.E. Hall, and A.A. da Silva Chronic effects of centrally administered adiponectin on appetite, metabolism and blood pressure regulation in normotensive and hypertensive rats Peptides 37 2012 1 5
4. M. Blatnik, and C.I. Soderstrom A practical guide for the stabilization of acylghrelin in human blood collections Clin Endocrinol (Oxf) 74 2011 325 331
5. D.E. Cummings, J.Q. Purnell, R.S. Frayo, K. Schmidova, B.E. Wisse, and D.S. Weigle A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans Diabetes 50 2001 1714 1719
6. D.E. Flanagan, M.L. Evans, T.P. Monsod, F. Rife, R.A. Heptulla, and W.V. Tamborlane The influence of insulin on circulating ghrelin Am J Physiol Endocrinol Metab 284 2003 313 316
7. L. Gautron, and J.K. Elmquist Sixteen years and counting: an update on leptin in energy balance J Clin Invest 121 2011 2087 2093
8. A. Katsuki, H. Urakawa, E.C. Gabazza, S. Murashima, K. Nakatani, and K. Togashi Circulating levels of active ghrelin is associated with abdominal adiposity, hyperinsulinemia and insulin resistance in patients with type 2 diabetes mellitus Eur J Endocrinol 151 2004 573 577
9. S. Kiyici, C. Ersoy, O. Oz Gul, E. Sarandol, M. Demirci, and E. Tuncel Total and acylated ghrelin levels in type 2 diabetic patients: similar levels observed after treatment with metformin, pioglitazone or diet therapy Exp Clin Endocrinol Diabetes 117 2009 386 390
10. I. Kusaka, S. Nagasaka, H. Horie, and S. Ishibashi Metformin, but not pioglitazone, decreases postchallenge plasma ghrelin levels in type 2 diabetic patients: a possible role in weight stability Diabetes Obes Metab 10 2008 1039 1046
11. C.K. Martin, A.K. Gupta, S.R. Smith, F.L. Greenway, H. Han, and G.A. Bray Effect of pioglitazone on energy intake and ghrelin in diabetic patients Diabetes Care 33 2010 742 744
12. D.R. Matthews, J.P. Hosker, A.S. Rudenski, B.A. Naylor, D.F. Treacher, and R.C. Turner Homeostasis model assessment: insulin resistance and b-cell function from fasting plasma glucose and insulin concentrations in man Diabetologia 28 1985 412 419
13. Y. Saitoh, R. Liu, H. Ueno, M. Mizuta, and M. Nakazato Oral pioglitazone administration increases food intake through ghrelin-independent pathway in Zucker fatty rat Diabetes Res Clin Pract 77 2007 351 356
14. P.K. Sharma, A. Bhansali, R. Sialy, S. Malhotra, and P. Pandhi Effects of pioglitazone and metformin on plasma adiponectin in newly detected type 2 diabetes mellitus Clin Endocrinol (Oxf) 65 2006 722 728
15. K. Tsuchiya, I. Akaza, T. Yoshimoto, and Y. Hirata Pioglitazone improves endothelial function with increased adiponectin and high-density lipoprotein cholesterol levels in type 2 diabetes Endocr J 56 2009 691 698
16. A.M. Wren, L.J. Seal, M.A. Cohen, R.L. Batterham, S. Taheri, and S.A. Stanley Ghrelin enhances appetite and increases food intake in humans J Clin Endocrinol Metab 86 2001 5992 5995
17. H. Yki-Jarvinen Thiazolidinediones N Engl J Med 351 2004 1106 1118