Toxicological Effects of the Different Substances in Tobacco Smoke on Human Embryonic Development by a Systems Chemo-Biology Approach

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Feltes, Bruno César ^a   Poloni, Joice de Faria ^b   Notari, Daniel Luis ^b   Bonatto, Diego ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b UNIVERSITY OF CAXIAS DO SUL   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINE; RETINOIC ACID; RETINOIC ACID RECEPTOR; TOBACCO SMOKE; PROSTAGLANDIN; SMOKE;

ARTICLE; CELL CYCLE ARREST; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EMBRYOTOXICITY; FEMALE; FETUS; FETUS MALFORMATION; HUMAN; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PREGNANT WOMAN; PRENATAL EXPOSURE; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION; SYSTEMS BIOLOGY; BONE; CELL COMMUNICATION; CELL PROLIFERATION; CHEMISTRY; CLUSTER ANALYSIS; CYTOLOGY; DRUG EFFECTS; EMBRYOLOGY; METABOLISM; OXIDATION REDUCTION REACTION; PREGNANCY; PROCEDURES; PROTEIN PROTEIN INTERACTION; SMOKE; TOBACCO; TOXICITY; TOXICOLOGY;

NICOTIANA TABACUM;

BONE AND BONES; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CLUSTER ANALYSIS; EMBRYONIC DEVELOPMENT; FEMALE; FETUS; HUMANS; NICOTINE; OXIDATION-REDUCTION; PREGNANCY; PROSTAGLANDINS; PROTEIN INTERACTION MAPS; SIGNAL TRANSDUCTION; SMOKE; SYSTEMS BIOLOGY; TOBACCO; TOXICOLOGY; TRETINOIN;

EID: 84876941422     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061743     Document Type: Article

References (62)

1. Pfeifer GP, Denissenko MF, Olivier M, Tretyakova N, Hecht SS, et al. (2002) Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers. Oncogene 21(48): 7435-7451.
2. Fowles J, Bates M (2000). The chemical constituents in cigarette and cigarette smoke: priorities for harm reduction. Available: http://www.moh.govt.nz/moh.nsf/pagescm/1003/File/chemicalconstituentscigarettespriorities.pdf. Accessed 2013 March 26.
3. Hackshaw A, Rodeck C, Boniface S, (2011) Maternal smoking in pregnancy and birth defects: a systematic review based on 173 687 malformed cases and 11.7 million controls. Human Reprod Update 17(5): 589-604.
4. Florescu A, Ferrence R, Einarson T, Selby P, Soldin O, et al. (2009) Methods for quantification of exposure to cigarette smoking and environmental tobacco smoke: focus on developmental toxicology. Ther Drug Monit 31(1): 14-30.
5. Morris CV, DiNieri JA, Szutorisz H, Hurd YL, (2011) Molecular mechanisms of maternal cannabis and cigarette use on human neurodevelopment. Eur J Neurosci 34(10): 1574-1583.
6. Sadeu JC, Foster WG, (2011) Cigarette smoke condensate exposure delays follicular development and function in a stage-dependent manner. Fertil Steril 95(7): 2410-2417.
7. Jauniaux E, Burton GJ, (2007) Morphological and biological effects of maternal exposure to tobacco smoke on the feto-placental unit. Early Hum Dev 83(11): 699-706.
8. Duester G, (2008) Retinoic acid synthesis and signaling during early organogenesis. Cell 134(6): 921-931.
9. Daftary GS, Taylor HS, (2006) Endocrine regulation of HOX genes. Endocr Rev 27(4): 331-355.
10. Cheng CG, Lin B, Dawson MI, Zhang XK, (2002) Nicotine modulates the effects of retinoids on growth inhibition and RARβ expression in lung cancer cells. Int J Cancer 99 (2): 171-178.
11. Votavova H, Dostalova M, Krejcik Z, Fejglova K, Vasikova A, et al. (2012) Deregulation of gene expression induced by environmental tobacco smoke exposure in pregnancy. Nicotine Tob Res 14(9): 1073-1082.
12. Jensen LJ, Kuhn M, Stark M, Chaffron S, Creevey C, et al. (2009) STRING 8- a global view on proteins and their functional interactions in 630 organisms. Nucleic Acids Res 37: D412-D416.
13. Snel B, Lehmann G, Bork P, Huynen MA, (2000) STRING: a web-server to retrieve and display the repeatedly occurring neighbourhood of a gene. Nucleic Acid Res 28(18): 3442-3444.
14. Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, et al. (2003) Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res 13: 2498-2504.
15. Rebhan M, Chalifa-Caspi V, Prilusky J, Lancet D, (1997) GeneCards: integrating information about genes, proteins and diseases. Trends Genet 13: 163.
16. Safran M, Dalah I, Alexander J, Rosen N, Iny Stein T, et al. (2010) GeneCards Version 3: the human gene integrator Database. Database (Oxford) 2010: baq020.
17. Kanehisa M, Goto S, (2000) KEGG: Kyoto encyclopedia of genes and genomes. Nucleic Acids Res 28: 27-30.
18. Hoffmann R, Valencia A, (2004) A gene network for navigating the literature. Nature Genetics 36: 664.
19. Tetko IV, Tanchuk VY, (2002) Application of associative neural networks for prediction of lipophilicity in ALOGPS 2.1 program. J Chem Inf Comput Sci 42(5): 1136-1145.
20. Carbon S, Ireland A, Mungall CJ, Shu S, Marshall B, et al. (2009) AmiGO: online access to ontology and annotation data. Bioinformatics 25(2): 288-289.
21. Kapushesky M, Emam I, Holloway E, Kurnosov P, Zorin A (2010) Gene expression atlas at the european bioinformatics institute. Nucleic Acids Res 38(Database issue): D690-D698.
22. Kapushesky M, Adamusiak T, Burdett T, Culhane A, Farne A, et al. (2012) Gene Expression Atlas update-a value-added database of microarray and sequencing-based functional genomics experiments. Nucleic Acids Res (Database issue): D1077-D1081.
23. Castro MA, Filho JL, Dalmolin RJ, Sinigaglia M, Moreira JC, et al. (2009) ViaComplex: software for landscape analysis of gene expression networks in genomic context. Bioinformatics 25(11): 1468-1469.
24. Bader GD, Hogue CW, (2003) An automated method for finding molecular complexes in large protein interaction networks. BMC Bioinformatics 4: 2.
25. Scardoni G, Petrerlini M, Laudanna C, (2009) Analyzing biological network parameters with CentiScaPe. Bioinformatics 25(21): 2857-2859.
26. Newman MEJ, (2005) A measure of betweenness centrality based on random walks. Soc Networks 27: 39-54.
27. Maere S, Heymans K, Kuiper M, (2005) BiNGO: a Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks. Bioinformatics 21(16): 3448-3449.
28. Benjamini Y, Hochberg Y, (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc B 57: 289-300.
29. Rosado JO, Henriques JP, Bonatto D, (2011) A systems pharmacology analysis of major chemotherapy combination regimens used in gastric cancer treatment: predicting potential new protein targets and drugs. Curr Cancer Drug Targets 11(7): 849-869.
30. Yu H, Kim PM, Sprecher E, Trifonov V, Gerstein M, (2007) The importance of bottlenecks in protein networks: correlation with gene essentiality and expression dynamics. PLoS Comput Biol 3(4): e59.
31. van der Toorn M, Rezayat D, Kauffman HF, Bakker SJ, Gans RO, et al. (2009) Lipid-soluble components in cigarette smoke induce mitochondrial production of reactive oxygen species in lung epithelial cells. Am J Physiol Lung Cell Mol Physiol 297(1): L109-L114.
32. Menon R, Fortunato SJ, Yu J, Milne GL, Sanchez S, et al. (2011) Cigarette smoke induces oxidative stress and apoptosis in normal term fetal membranes. Placenta 32(4): 317-322.
33. Yao H, Yang SR, Kode A, Rajendrasozhan S, Caito S, et al. (2007) Redox regulation of lung inflammation: role of NADPH oxidase and NF-kappaB signaling. Biochem Soc Trans 35(Pt 5): 1151-1155.
34. Yao H, Edirisinghe I, Yang SR, Rajendrasozhan S, Kode A, et al. (2008) Genetic ablation of NADPH oxidase enhances susceptibility to cigarette smoke-induced lung inflammation and emphysema in mice. Am J Pathol 172(5): 1222-1237.
35. Haeggström JZ, Funk CD, (2011) Lipoxygenase and leukotriene pathways: biochemistry, biology, and roles in disease. Chem Rev 111(10): 5866-5898.
36. Ylikorkala O, Viinikka L, (1992) The role of prostaglandins in obstetrical disorders. Baillieres Clin Obstet Gynaecol 6(4): 809-827.
37. Lantz RC, Hays AM, (2006) Role of oxidative stress in arsenic-induced toxicity. Drug Metab Rev 38(4): 791-804.
38. Board PG, Menon D (2012) Glutathione transferases, regulators of cellular metabolism and physiology. Biochim Biophys Acta.
39. Moledina F, Clarke G, Oskooei A, Onishi K, Günther A, et al. (2012) Predictive microfluidic control of regulatory ligand trajectories in individual pluripotent cells. Proc Natl Acad Sci U S A 109(9): 3264-3269.
40. Loureiro B, Oliveira LJ, Favoreto MG, Hansen PJ, (2011) Colony-stimulating factor 2 inhibits induction of apoptosis in the bovine preimplantation embryo. Am J Reprod Immunol 65(6): 578-588.
41. Kim YJ, Lee GS, Hyun SH, Ka HH, Choi KC, et al. (2009) Uterine expression of epidermal growth factor family during the course of pregnancy in pigs. Reprod Domest Anim 44(5): 797-804.
42. Shilo BZ, (2005) Regulating the dynamics of EGF receptor signaling in space and time. Development 132(18): 4017-4027.
43. Delpretti S, Zakany J, Duboule D, (2012) A function for all posterior Hoxd genes during digit development? Dev Dyn 241(4): 792-802.
44. Singh AB, Harris RC, (2005) Autocrine, paracrine and juxtacrine signaling by EGFR ligands. Cell Signal 17(10): 1183-1193.
45. Nyhan WL, (2005) Disorders of purine and pyrimidine metabolism. Mol Genet Metab 86(1-2): 25-33.
46. Goggin M, Sangaraju D, Walker VE, Wickliffe J, Swenberg JA, et al. (2011) Persistence and repair of bifunctional DNA adducts in tissues of laboratory animals exposed to 1,3-butadiene by inhalation. Chem Res Toxicol 24(6): 809-817.
47. Koturbash I, Scherhag A, Sorrentino J, Sexton K, Bodnar W, et al. (2011) Epigenetic mechanisms of mouse interstrain variability in genotoxicity of the environmental toxicant 1,3-butadiene. Toxicol Sci 122(2): 448-456.
48. Kauffman SL, (1969) Cell proliferation in embryonic mouse neural tube following urethane exposure. Dev Biol 20(2): 146-157.
49. Breiling A, Sessa L, Orlando V, (2007) Biology of polycomb and trithorax group proteins. Int Rev Cytol 258: 83-136.
50. Matarazzo MR, De Bonis ML, Strazzullo M, Cerase A, Ferraro M, et al. (2007) Multiple binding of methyl-CpG and polycomb proteins in long-term gene silencing events. J Cell Physiol 210(3): 711-719.
51. Ma L, Zheng LW, Sham MH, Cheung LK, (2010) Uncoupled angiogenesis and osteogenesis in nicotine-compromised bone healing. J Bone Miner Res 26(6): 1305-1313.
52. Lopatina N, Haskell JF, Andrews LG, Poole JC, Saldanha S, et al. (2002) Differential maintenance and de novo methylating activity by three DNA methyltransferases in aging and immortalized fibroblasts. J Cell Biochem 84(2): 324-334.
53. Xu Y, Zhang Y, Cardell LO, (2010) Nicotine enhances murine airway contractile responses to kinin receptor agonists via activation of JNK- and PDE4-related intracellular pathways. Respir Res 11: 13.
54. León Y, Sanchez JA, Miner C, Ariza-McNaughton L, Represa JJ, et al. (1995) Developmental regulation of Fos-protein during proliferative growth of the otic vesicle and its relation to differentiation induced by retinoic acid. Dev Biol 167(1): 75-86.
55. Srinivas H, Juroske DM, Kalyankrishna S, Cody D, Price RE, et al. (2005) c-Jun N-terminal kinase contributes to aberrant retinoid signaling in lung cancer cells by phosphorylating and inducing proteasomal degradation of retinoic acid receptor alpha. Mol Cell Biol 25(3): 1054-1069.
56. Han BC, Xia HF, Sun J, Yang Y, Peng JP, (2010) Retinoic acid-metabolizing enzyme cytochrome P450 26a1 (CYP26A1) is essential for implantation- functional study of its role in early pregnancy. J Cell Physiol 223(2): 471-479.
57. Feltes BC, de Faria Poloni J, Bonatto D, (2011) The developmental aging and origins of health and disease hypotheses explained by different protein networks. Biogerontology 12(4): 293-308.
58. David P, Sabapathy K, Hoffmann O, Idarraga MH, Wagner EF, (2002) JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and-independent mechanisms. J Cell Sci 115(22): 4317-4325.
59. Yildiz D, (2004) Nicotine, its metabolism and an overview of its biological effects. Toxicon 43: 619-632.
60. Kawakita A, Sato K, Makino H, Ikegami H, Takayama S, et al. (2008) Nicotine Acts on Growth Plate Chondrocytes to Delay Skeletal Growth through the α7 Neuronal Nicotinic Acetylcholine Receptor. PLoS One 3(12): e3945.
61. Nakayama Y, Mezawa M, Araki S, Sasaki Y, Wang S, et al. (2009) Nicotine suppresses bone sialoprotein gene expression. J Periodont Res 44: 657-663.
62. Benowitz NL, Hukkanen J, Jacob P 3rd (2009) Nicotine chemistry, metabolism, kinetics and biomarkers. Handb Exp Pharmacol 192: 29-60.