Differences in interaction and subgroup-specific effects were observed between randomized and nonrandomized studies in three empirical examples

Journal of Clinical Epidemiology

Volumn 66, Issue 6, 2013, Pages 599-607

  Schmidt, Amand F ^a,b,c   Rovers, Maroeska M ^d   Klungel, Olaf H ^a,b   Hoes, Arno W ^a   Knol, Mirjam J ^a   Nielen, Mirjam ^c   De Boer, Antonius ^b   Groenwold, Rolf H H ^a,b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

^d RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Effect modification; Individual patient data meta analyses; Interaction; Nonrandomized; Randomized; Subgroups

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PLACEBO;

BREAST CANCER; CANCER MORTALITY; COMPARATIVE STUDY; CONFIDENCE INTERVAL; CORONARY ARTERY BYPASS SURGERY; DRUG EFFECT; GROUP DYNAMICS; HUMAN; MAMMOGRAPHY; OBSERVATIONAL STUDY; PATIENT CODING; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW;

BREAST NEOPLASMS; CORONARY ARTERY BYPASS; CORONARY DISEASE; DIABETES MELLITUS; EFFECT MODIFIER, EPIDEMIOLOGIC; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MAMMOGRAPHY; MASS SCREENING; META-ANALYSIS AS TOPIC; ODDS RATIO; PERCUTANEOUS CORONARY INTERVENTION; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RESEARCH DESIGN;

EID: 84876907682     PISSN: 08954356     EISSN: 18785921     Source Type: Journal    
DOI: 10.1016/j.jclinepi.2012.08.008     Document Type: Review

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