Banff initiative for quality assurance in transplantation (BIFQUIT): Reproducibility of C4d immunohistochemistry in kidney allografts

American Journal of Transplantation

Volumn 13, Issue 5, 2013, Pages 1235-1245

  Mengel, M ^a   Chan, S ^a   Climenhaga, J ^a   Kushner, Y B ^b   Regele, H ^c   Colvin, R B ^b   Randhawa, P ^d  

^a UNIVERSITY OF ALBERTA   (Canada)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c MEDICAL UNIVERSITY OF INNSBRUCK   (Austria)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Banff classification; C4d; immunohistochemistry; transplantation

Indexed keywords

COMPLEMENT COMPONENT C4D; PARAFFIN;

ARTICLE; HUMAN; IMMUNOHISTOCHEMISTRY; KAPPA STATISTICS; KIDNEY ALLOGRAFT; KIDNEY TRANSPLANTATION; PRIORITY JOURNAL; QUALITY CONTROL; REPRODUCIBILITY; TISSUE MICROARRAY;

COMPLEMENT C4B; GRAFT REJECTION; HUMANS; IMMUNOHISTOCHEMISTRY; KIDNEY; KIDNEY TRANSPLANTATION; OBSERVER VARIATION; PEPTIDE FRAGMENTS; QUALITY ASSURANCE, HEALTH CARE; REPRODUCIBILITY OF RESULTS; TRANSPLANTATION, HOMOLOGOUS;

EID: 84876902083     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.12193     Document Type: Article

References (29)

1. Berry GJ, Angelini A, Burke MM, et al. The ISHLT working formulation for pathologic diagnosis of antibody-mediated rejection in heart transplantation: evolution and current status (2005-2011). J Heart Lung Transplant 2011; 30: 601-611.
2. Drachenberg CB, Torrealba JR, Nankivell BJ, et al. Guidelines for the diagnosis of antibody-mediated rejection in pancreas allograftsupdated Banff grading schema. Am J Transplant 2011; 11: 1792-1802.
3. Racusen LC, Colvin RB, Solez K, et al. Antibody-mediated rejection criteria-an addition to the Banff 97 classification of renal allograft rejection. Am J Transplant 2003; 3: 708-714.
4. Solez K, Colvin RB, Racusen LC, et al. Banff 07 classification of renal allograft pathology: updates and future directions. Am J Transplant 2008; 8: 753-760.
5. Mengel M, Sis B, Haas M, et al. Banff 2011 Meeting Report: New Concepts in Antibody-Mediated Rejection. Am J Transplant 2012; 12: 563-570.
6. Sis B, Mengel M, Haas M, et al. Banff '09 Meeting Report: Antibody Mediated Graft Deterioration and Implementation of Banff Working Groups. Am J Transplant 2010; 10: 464-471.
7. Goldstein NS, Hewitt SM, Taylor CR, Yaziji H, Hicks DG. Recommendations for improved standardization of immunohistochemistry. Appl Immunohistochem Mol Morphol 2007; 15: 124-133.
8. Torlakovic EE, Riddell R, Banerjee D, et al. Canadian Association of Pathologists-Association canadienne des pathologistes National Standards Committee/Immunohistochemistry: best practice recommendations for standardization of immunohistochemistry tests. Am J Clin Pathol 2010; 133: 354-365.
9. Clinical and Laboratory Standards Institute. Quality Assurance for Design Control and Implementation of Immunohistochemistry Assays: Approved Guideline. 2 ed. Wayne, PA, USA: CLSI, 2011.
10. Taylor CR. New revised Clinical and Laboratory Standards Institute Guidelines for Immunohistochemistry and Immunocytochemistry. Appl Immunohistochem Mol Morphol 2011; 19: 289-290.
11. Mengel M, von Wasielewski R, Wiese B, Rudiger T, Muller-Hermelink HK, Kreipe H. Inter-laboratory and inter-observer reproducibility of immunohistochemical assessment of the Ki-67 labelling index in a large multi-centre trial. J Pathol 2002; 198: 292-299.
12. Mengel M, Kreipe H, von Wasielewski R. Rapid and large-scale transition of new tumor biomarkers to clinical biopsy material by innovative tissue microarray systems. Appl Immunohistochem Mol Morphol 2003; 11: 261-268.
13. Altman DG, Bland JM. Measurement in medicine: the analysis of method comparison studies. Statistician 1983; 32: 307-317.
14. Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics 1977; 33: 159-174.
15. Wasielewski R, Hasselmann S, Ruschoff J, Fisseler-Eckhoff A, Kreipe H. Proficiency testing of immunohistochemical biomarker assays in breast cancer. Virchows Arch 2008; 453: 537-543.
16. Sis B, Jhangri G, Bunnag S, Allanach K, Kaplan B, Halloran PF. Endothelial gene expression in kidney transplants with alloantibody indicates antibody-mediated damage despite lack of C4d staining. Am J Transplant 2009; 9: 2312-2323.
17. Archdeacon P, Chan M, Neuland C, et al. Summary of FDA antibody-mediated rejection workshop. Am J Transplant 2011; 11: 896-906.
18. Colvin RB. Antibody-mediated renal allograft rejection: diagnosis and pathogenesis. J Am Soc Nephrol 2007; 18: 1046-1056.
19. Wiebe C, Gibson IW, Blydt-Hansen TD, et al. Evolution and clinical pathologic correlations of de novo donor-specific HLA antibody post kidney transplant. Am J Transplant 2012; 12: 1157-1167.
20. Seemayer CA, Gaspert A, Nickeleit V, Mihatsch MJ. C4d staining of renal allograft biopsies: a comparative analysis of different staining techniques. Nephrol Dial Transplant 2007; 22: 568-576.
21. Chantranuwat C, Qiao JH, Kobashigawa J, Hong L, Shintaku P, Fishbein MC. Immunoperoxidase staining for C4d on paraffinembedded tissue in cardiac allograft endomyocardial biopsies: comparison to frozen tissue immunofluorescence. Appl Immunohistochem Mol Morphol 2004; 12: 166-171.
22. Nadasdy GM, Bott C, Cowden D, Pelletier R, Ferguson R, Nadasdy T. Comparative study for the detection of peritubular capillary C4d deposition in human renal allografts using different methodologies. Human Pathol 2005; 36: 1178-1185.
23. Mengel M, Sis B, Halloran PF. SWOT analysis of Banff: Strengths, Weaknesses, Opportunities, and Threats of the international Banff consensus process and classification system for renal allograft pathology. Am J Transplant 2007; 7: 2221-2226.
24. Furness PN, Taub N, Assmann KJ, et al. International variation in histologic grading is large, and persistent feedback does not improve reproducibility. Am J Surg Pathol 2003; 27: 805-810.
25. Kedainis RL, Koch MJ, Brennan DC, Liapis H. Focal C4d+ in renal allografts is associated with the presence of donor-specific antibodies and decreased allograft survival. Am J Transplant 2009; 9: 812-819.
26. Kikic Z, Regele H, Nordmeyer V, et al. Significance of peritubular capillary, glomerular, and arteriolar C4d staining patterns in paraffin sections of early kidney transplant biopsies. Transplant 2011; 91: 440-446.
27. Magil AB, Tinckam KJ. Focal peritubular capillary C4d deposition in acute rejection. Nephrol Dial Transplant 2006; 21: 1382-1388.
28. Worthington JE, McEwen A, McWilliam LJ, Picton ML, Martin S. Association between C4d staining in renal transplant biopsies, production of donor-specific HLA antibodies, and graft outcome. Transplant 2007; 83: 398-403.
29. Brazdziute E, Laurinavicius A. Digital pathology evaluation of complement C4d component deposition in the kidney allograft biopsies is a useful tool to improve reproducibility of the scoring. Diagn Pathol 2011; 6(Suppl 1): S5.