New radioligands for describing the molecular pharmacology of MT1 and MT2 melatonin receptors

International Journal of Molecular Sciences

Volumn 14, Issue 5, 2013, Pages 8948-8962

  Legros, Céline ^a   Matthey, Ulrich ^b   Grelak, Teresa ^b   Pedragona Moreau, Sandrine ^c   Hassler, Werner ^d   Yous, Saïd ^e   Thomas, Emmanuel ^f   Suzenet, Franck ^g   Folleas, Benoît ^f   Lefoulon, François ^c   Berthelot, Pascal ^e   Caignard, Daniel Henri ^a   Guillaumet, Gérald ^g   Delagrange, Philippe ^a   Brayer, Jean Louis ^f   Nosjean, Olivier ^a   Boutin, Jean A ^a  

^a INSTITUT DE RECHERCHES SERVIER   (France)

^b CELERION   (United States)

^c INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

^d ANAWA Trading SA   (Switzerland)

^e UNIV LILLE   (France)

^f DIVERCHIM   (France)

^g UNIVERSITÉ D'ORLÉANS   (France)

Author keywords

2 iodomelatonin; Alternative radioligands; Melatonin receptors; Radiolabeling; Synthesis

Indexed keywords

2 IODO N 2 [5 METHOXY 2 (NAPHTHALEN 1 YL) 1H PYRROLO[3,2 B]PYRIDINE 3 YL]ACETAMIDE; 2 [2 [(2 IODO 4,5 DIMETHOXYPHENYL)METHYL] 4,5 DIMETHOXYPHENYL]ACETATE; ACETAMIDE DERIVATIVE; ACETIC ACID DERIVATIVE; CHEMICAL COMPOUND; GUANOSINE TRIPHOSPHATE; IODINE 125; ISOPROTEIN; MELATONIN; MELATONIN 1 RECEPTOR; MELATONIN 2 RECEPTOR; N [2 (5 METHOXY 1H INDOL 3 YL)ETHYL]IODOACETAMIDE; RADIOLIGAND; RECOMBINANT MELATONIN 1 RECEPTOR; RECOMBINANT MELATONIN 2 RECEPTOR; RECOMBINANT RECEPTOR; UNCLASSIFIED DRUG; 2-IODOMELATONIN; LIGAND; RADIOPHARMACEUTICAL AGENT; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; MOLECULAR BIOLOGY; NONHUMAN; PHARMACOLOGY; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RECEPTOR AFFINITY; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; CHO CELL LINE; CRICETULUS; HAMSTER; HUMAN; KINETICS; METABOLISM; REGRESSION ANALYSIS;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; KINETICS; LIGANDS; MELATONIN; RADIOPHARMACEUTICALS; RECEPTOR, MELATONIN, MT1; RECEPTOR, MELATONIN, MT2; RECOMBINANT PROTEINS; REGRESSION ANALYSIS;

EID: 84876900594     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms14058948     Document Type: Article

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